| Uniprot ID: | Q13887 |
| Secondary ID: | A2TJX0 |
| Symbol: | KLF5 |
| Other Name: | BTEB2,Basic transcription element-binding protein 2,BTE-binding protein 2,Colon krueppel-like factor,GC-box-binding protein 2,Intestinal-enriched krueppel-like factor,Transcription factor BTEB2 |
| Class: | Single Protein |
| Type: | pro-fibrotic |
| Molecular Function: | Activator,DNA-binding |
| Category I | Category II | Category III |
|---|---|---|
| Intracellular | Other transcription factor | Transcription activator |
| Target ID | Name | Interaction |
|---|---|---|
| D0509 | LE135 | antagonist |
Reference Record 1
| PubMed ID | 20038803 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | fibroblasts proliferation | ||
| Process III | prevenet collagen deposition | ||
| Mechanism | Targeting IGF-1 | ||
Reference Record 2
| PubMed ID | 12101409 | Compound ID | |
| CAS | Name | ||
| Model | vitro,mice | Fibrosis Disease | Cardiac fibrosis |
| Process I | |||
| Process II | |||
| Process III | prevenet collagen deposition | ||
| Mechanism | |||
Reference Record 3