Transcription factor AP-1

Basic Information

Uniprot ID:	P05412
Secondary ID:	Q6FHM7, Q96G93
Symbol:	JUN
Other Name:	Activator protein 1,AP1,Proto-oncogene c-Jun,V-jun avian sarcoma virus 17 oncogene homolog,p39
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Activator,DNA-binding

Target Classification

Category I	Category II	Category III
Intracellular	Other transcription factor	Transcription activator

Related Compound

Target ID	Name	Interaction
D0351	T-5224	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	22139817	Compound ID	D0351
CAS	530141-72-1	Name	T-5224
Model	vitro,human,mice	Fibrosis Disease	Systemic sclerosis
Process I
Process II	fibroblasts activation,fibroblasts differentiation
Process III	prevenet collagen deposition
Mechanism