Sterol regulatory element-binding protein 1

Basic Information


Uniprot ID: P36956
Secondary ID: B0I4X3
Symbol: SREBF1
Other Name: BHLHD1,SREBP-1,Class D basic helix-loop-helix protein 1,bHLHd1,Sterol regulatory element-binding transcription factor 1,Processed sterol regulatory element-binding protein 1
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Activator,DNA-binding


Target Classification


Category I Category II Category III
Intracellular Other transcription factor Transcription activator

Related Compound


Target ID Name Interaction
D0552 Fatostatin inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 27385736 Compound ID D0552
CAS 298197-04-3 Name Fatostatin
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II fibroblasts activation
Process III prevenet collagen deposition
Mechanism