CREB-binding protein

Basic Information

Uniprot ID:	Q92793
Secondary ID:	D3DUC9
Symbol:	CREBBP
Other Name:	CBP
Class:	Epigenetics
Type:	pro-fibrotic
Molecular Function:	Activator,Acyltransferase,Transferase

Target Classification

Category I	Category II	Category III
Intracellular	Epigenetics	Writer

Related Compound

Target ID	Name	Interaction
D0045	ICG-001	antagonist

Fibrosis Related Property

Reference Record 1

PubMed ID	28578904	Compound ID	D0045
CAS	780757-88-2	Name	ICG-001
Model	vitro	Fibrosis Disease	Renal fibrosis
Process I	attenue inflammation
Process II
Process III	prevenet collagen deposition
Mechanism	Targeting RAS signaling, Wnt/β-catenin signaling

Reference Record 2

PubMed ID	27307790	Compound ID	D0045
CAS	780757-88-2	Name	ICG-001
Model	vitro,mice	Fibrosis Disease	Liver fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 3

PubMed ID	25012166	Compound ID	D0045
CAS	780757-88-2	Name	ICG-001
Model	vitro,mice	Fibrosis Disease	Renal fibrosis
Process I	attenue inflammation
Process II
Process III	prevenet collagen deposition
Mechanism	Targeting Wnt/β-catenin signaling