Serpin H1

Basic Information

Uniprot ID: P50454
Secondary ID: B3KVJ3
Symbol: SERPINH1
Other Name: CBP1,47 kDa heat shock protein,Arsenic-transactivated protein 3,AsTP3,Cell proliferation-inducing gene 14 protein,Collagen-binding protein,Colligin,Rheumatoid arthritis-related antigen RA-A47
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Chaperone

Target Classification

Category I Category II Category III
Intracellular Other

Related Compound

Target ID Name Interaction
D0232 ZINC15085064 inhibitor
D0233 ZINC65001938 inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 26091621 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 25525267 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Liver fibrosis
Process I
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 25522881 Compound ID D0232
CAS 1240753-77-8 Name ZINC15085064
Model Fibrosis Disease Fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 4

PubMed ID 25522881 Compound ID D0233
CAS 1358547-63-3 Name ZINC65001938
Model Fibrosis Disease Fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 5

PubMed ID 24295791 Compound ID
CAS Name
Model vitro,human,mice Fibrosis Disease Liver fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 6

PubMed ID 21144841 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Intestinal fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 7

PubMed ID 18376398 Compound ID
CAS Name
Model vitro,rat Fibrosis Disease Liver fibrosis
Process I
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism

Reference Record 8

PubMed ID 17890856 Compound ID
CAS Name
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 9

PubMed ID 29035148 Compound ID
CAS Name
Model rat Fibrosis Disease Pulmonary fibrosis
Process I
Process II myofibroblast apoptosis
Process III
Mechanism

Reference Record 10

PubMed ID 29025875 Compound ID
CAS Name
Model vitro Fibrosis Disease Fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism