Rho-associated protein kinase

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class: Protein Famliy
Type: pro-fibrotic
Molecular Function:

Target Classification

Category I Category II Category III
Other

Related Compound

Target ID Name Interaction
D0306 Y27632 inhibitor
D1044 Poly (ADP-ribose) polymerase inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 23550216 Compound ID D0306
CAS 146986-50-7 Name Y27632
Model vitro Fibrosis Disease Eye fibrosis
Process I
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 14615290 Compound ID
CAS Name
Model mice Fibrosis Disease Vascular fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 11967018 Compound ID D0306
CAS 146986-50-7 Name Y27632
Model vitro,mice Fibrosis Disease Renal fibrosis
Process I attenue inflammation
Process II fibroblasts proliferation
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 11961044 Compound ID D0306
CAS 146986-50-7 Name Y27632
Model rat Fibrosis Disease Vascular fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 5

PubMed ID 11961044 Compound ID D0306
CAS 146986-50-7 Name Y27632
Model rat Fibrosis Disease Cardiac fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 6

PubMed ID 21439370 Compound ID D1044
CAS 58319-92-9 Name Poly (ADP-ribose) polymerase
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism

Reference Record 7

PubMed ID 21439370 Compound ID D0306
CAS 146986-50-7 Name Y27632
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism