Calpain

Basic Information

Uniprot ID:	PF00648
Secondary ID:
Symbol:
Other Name:
Class:	Protein Famliy
Type:	pro-fibrotic
Molecular Function:

Target Classification

Category I	Category II	Category III
Other

Related Compound

Target ID	Name	Interaction
D0129	ALLN	inhibitor
D0139	MDL28170	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	27472894	Compound ID	D0129
CAS	110044-82-1	Name	ALLN
Model	vitro	Fibrosis Disease	Cardiac fibrosis
Process I
Process II	fibroblasts migration
Process III
Mechanism

Reference Record 2

PubMed ID	27261452	Compound ID	D0139
CAS	88191-84-8	Name	MDL28170
Model	vitro,human	Fibrosis Disease	Pleural fibrosis
Process I
Process II	cells proliferation
Process III	prevenet collagen deposition
Mechanism	Targeting PI3K/Akt/NF-κB signaling pathway