Mitogen-activated protein kinase

Basic Information


Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class: Protein Famliy
Type: pro-fibrotic
Molecular Function:


Target Classification


Category I Category II Category III
Other

Related Compound


Target ID Name Interaction
D0419 UO126 inhibitor

Fibrosis Related Property


Reference Record 1

PubMed ID 19434726 Compound ID D0419
CAS 109511-58-2 Name UO126
Model vitro,human Fibrosis Disease Liver fibrosis
Process I
Process II HSCs activation,HSCs proliferation
Process III prevenet collagen deposition
Mechanism Targeting ERK 1/2 and PI3K-Akt pathways