NAD(P)H oxidase

Basic Information

Uniprot ID:
Secondary ID:
Symbol:
Other Name:
Class: Protein Famliy
Type: pro-fibrotic
Molecular Function:

Target Classification

Category I Category II Category III
Other

Related Compound

Target ID Name Interaction
D0061 Apocynin inhibitor
D0260 Diphenylene iodonium inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 21537828 Compound ID D0260
CAS 244-54-2 Name Diphenylene iodonium
Model vitro Fibrosis Disease Peritoneal fibrosis
Process I
Process II EMT,myofibroblasts differentiation
Process III
Mechanism Targeting Pai-i and α-Sma

Reference Record 2

PubMed ID 18534653 Compound ID
CAS Name
Model mice Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II cells apoptosis
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 17962358 Compound ID D0260
CAS 244-54-2 Name Diphenylene iodonium
Model vitro,mice Fibrosis Disease Pancreatic fibrosis
Process I
Process II cells proliferation
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 17962358 Compound ID D0061
CAS 498-02-2 Name Apocynin
Model vitro,mice Fibrosis Disease Pancreatic fibrosis
Process I
Process II cells proliferation
Process III
Mechanism