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Escherichia coli strain BL21(DE3)
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2.7.7.84 2'-5' oligoadenylate synthase.
Bioparts catalyze this reaction
Biopart ID | Organisms | pH | temperature(ºC) | km |
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Qualitative and quantitative parameters:
Taxonomy
Protein sequence
Sequence
Protein family
Protein structure
Nucleotide sequences (Optimized nucleotide sequences according to different chassises)
Sequence
- D Ferbus; J Justesen; F Besançon; M N Thang; . 1981: The 2'5' oligoadenylate synthetase has a multifunctional 2'5' nucleotidyl-transferase activity. Biochemical and Biophysical Research Communications, 100 847-56.
- R J Suhadolnik; M B Flick; J D Mosca; Y Sawada; P W Doetsch; E C Vonderheid; . 1983: 2',5'-oligoadenylate synthetase from cutaneous T-cell lymphoma: biosynthesis, identification, quantitation, molecular size of the 2',5'-oligoadenylates, and inhibition of protein synthesis. Biochemistry, 22 4153-8.
- A K Wintero; M Fredholm; W Davies; . 1996: Evaluation and characterization of a porcine small intestine cDNA library: analysis of 839 clones. Mammalian genome : official journal of the International Mammalian Genome Society, 7 509-17.
- R Hartmann; G Walko; J Justesen; . 2001: Inhibition of 2'-5' oligoadenylate synthetase by divalent metal ions. Febs Letters, 507 54-8.
- Aruna K Behera; Mukesh Kumar; Richard F Lockey; Shyam S Mohapatra; . 2002: 2'-5' Oligoadenylate synthetase plays a critical role in interferon-gamma inhibition of respiratory syncytial virus infection of human epithelial cells. The Journal of Biological Chemistry, 277 25601-8.
- Rune Hartmann; Just Justesen; Saumendra N Sarkar; Ganes C Sen; Vivien C Yee; . 2003: Crystal structure of the 2'-specific and double-stranded RNA-activated interferon-induced antiviral protein 2'-5'-oligoadenylate synthetase. Molecular Cell, 12 1173-85.
- Anna Kajaste-Rudnitski; Tomoji Mashimo; Marie-Pascale Frenkiel; Jean-Louis Guénet; Marianne Lucas; Philippe Desprès; . 2006: The 2',5'-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells. The Journal of Biological Chemistry, 281 4624-37.
- Ara G Hovanessian; Just Justesen; . 2007: The human 2'-5'oligoadenylate synthetase family: unique interferon-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation. Biochimie, 89 779-88.
- Heinz C Schröder; Filipe Natalio; Matthias Wiens; Muhammad Nawaz Tahir; Mohammed Ibrahim Shukoor; Wolfgang Tremel; Sergey I Belikov; Anatoli Krasko; Werner E G Müller; . 2008: The 2'-5'-oligoadenylate synthetase in the lowest metazoa: isolation, cloning, expression and functional activity in the sponge Lubomirskia baicalensis. Molecular Immunology, 45 945-53.
- S Torralba; J Sojat; R Hartmann; . 2008: 2'-5' oligoadenylate synthetase shares active site architecture with the archaeal CCA-adding enzyme. Cellular and Molecular Life Sciences, 65 2613-20.
- Helle Kristiansen; Christina A Scherer; Maralee McVean; Shawn P Iadonato; Susanne Vends; Karthiga Thavachelvam; Thomas B Steffensen; Kristy A Horan; Thomas Kuri; Friedemann Weber; Søren R Paludan; Rune Hartmann; . 2010: Extracellular 2'-5' oligoadenylate synthetase stimulates RNase L-independent antiviral activity: a novel mechanism of virus-induced innate immunity. Journal of Virology, 84 11898-904.
- Hui Meng; Soumya Deo; Shawn Xiong; Edis Dzananovic; Lynda J Donald; Cody W van Dijk; Sean A McKenna; . 2012: Regulation of the interferon-inducible 2'-5'-oligoadenylate synthetases by adenovirus VA(I) RNA. Journal of Molecular Biology, 422 635-49.