1) Transfers an alpha-D-mannosyl residue from GDP-mannose into lipid-linked oligosaccharide, forming an alpha-(1->6)-D-mannosyl-D-mannose linkage
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2.4.1.232 Initiation-specific alpha-1,6-mannosyltransferase.
Bioparts catalyze this reaction
Biopart ID | Organisms | pH | temperature(ºC) | km |
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Qualitative and quantitative parameters:
Temperature
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30.0
pH
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7.5
Taxonomy
Protein sequence
Sequence
Protein family
Nucleotide sequences (Optimized nucleotide sequences according to different chassises)
Sequence
- C L Yip; S K Welch; F Klebl; T Gilbert; P Seidel; F J Grant; P J O'Hara; V L MacKay; . 1994: Cloning and analysis of the Saccharomyces cerevisiae MNN9 and MNN1 genes required for complex glycosylation of secreted proteins. Proceedings of the National Academy of Sciences of the United States of America, 91 2723-7.
- Y Nakanishi-Shindo; K Nakayama; A Tanaka; Y Toda; Y Jigami; . 1993: Structure of the N-linked oligosaccharides that show the complete loss of alpha-1,6-polymannose outer chain from och1, och1 mnn1, and och1 mnn1 alg3 mutants of Saccharomyces cerevisiae. The Journal of Biological Chemistry, 268 26338-45.
- H Kojima; H Hashimoto; K Yoda; . 1999: Interaction among the subunits of Golgi membrane mannosyltransferase complexes of the yeast Saccharomyces cerevisiae. Bioscience, biotechnology, and biochemistry, 63 1970-6.
- T Yoko-o; K Tsukahara; T Watanabe; N Hata-Sugi; K Yoshimatsu; T Nagasu; Y Jigami; . 2001: Schizosaccharomyces pombe och1(+) encodes alpha-1,6-mannosyltransferase that is involved in outer chain elongation of N-linked oligosaccharides. Febs Letters, 489 75-80.
- V Wood; R Gwilliam; M-A Rajandream; M Lyne; R Lyne; A Stewart; J Sgouros; N Peat; J Hayles; S Baker; D Basham; S Bowman; K Brooks; D Brown; S Brown; T Chillingworth; C Churcher; M Collins; R Connor; A Cronin; P Davis; T Feltwell; A Fraser; S Gentles; A Goble; N Hamlin; D Harris; J Hidalgo; G Hodgson; S Holroyd; T Hornsby; S Howarth; E J Huckle; S Hunt; K Jagels; K James; L Jones; M Jones; S Leather; S McDonald; J McLean; P Mooney; S Moule; K Mungall; L Murphy; D Niblett; C Odell; K Oliver; S O'Neil; D Pearson; M A Quail; E Rabbinowitsch; K Rutherford; S Rutter; D Saunders; K Seeger; S Sharp; J Skelton; M Simmonds; R Squares; S Squares; K Stevens; K Taylor; R G Taylor; A Tivey; S Walsh; T Warren; S Whitehead; J Woodward; G Volckaert; R Aert; J Robben; B Grymonprez; I Weltjens; E Vanstreels; M Rieger; M Schäfer; S Müller-Auer; C Gabel; M Fuchs; A Düsterhöft; C Fritzc; E Holzer; D Moestl; H Hilbert; K Borzym; I Langer; A Beck; H Lehrach; R Reinhardt; T M Pohl; P Eger; W Zimmermann; H Wedler; R Wambutt; B Purnelle; A Goffeau; E Cadieu; S Dréano; S Gloux; V Lelaure; S Mottier; F Galibert; S J Aves; Z Xiang; C Hunt; K Moore; S M Hurst; M Lucas; M Rochet; C Gaillardin; V A Tallada; A Garzon; G Thode; R R Daga; L Cruzado; J Jimenez; M Sánchez; F del Rey; J Benito; A Domínguez; J L Revuelta; S Moreno; J Armstrong; S L Forsburg; L Cerutti; T Lowe; W R McCombie; I Paulsen; J Potashkin; G V Shpakovski; D Ussery; B G Barrell; P Nurse; L Cerrutti; . 2002: The genome sequence of Schizosaccharomyces pombe. Nature, 415 871-80.
- Katsuyoshi Yamamoto; Michiyo Okamoto; Takehiko Yoko-o; Yoshifumi Jigami; . 2003: Salt stress induces the expression of Schizosaccharomyces pombe och1+, which encodes an initiation-specific alpha-1,6-mannosyltransferase for N-linked outer chain synthesis of cell wall mannoproteins. Bioscience, biotechnology, and biochemistry, 67 927-9.
- Leena Karhinen; Marja Makarow; . 2004: Activity of recycling Golgi mannosyltransferases in the yeast endoplasmic reticulum. Journal of Cell Science, 117 351-8.
- Stéphanie Barnay-Verdier; Anita Boisramé; Jean-Marie Beckerich; . 2004: Identification and characterization of two alpha-1,6-mannosyltransferases, Anl1p and Och1p, in the yeast Yarrowia lipolytica. Microbiology (Reading, England), 150 2185-95.
- Kouji Goto; Yoshio Okawa; . 2008: Activity and stability of alpha- and beta-mannosyltransferases in Candida albicans cells cultured at high temperature and at low pH. Biological & pharmaceutical bulletin, 31 1333-6.
- Alexander Striebeck; David A Robinson; Alexander W Schüttelkopf; Daan M F van Aalten; . 2013: Yeast Mnn9 is both a priming glycosyltransferase and an allosteric activator of mannan biosynthesis. Open Biology, 3 130022.