The “HUABIAO” whole-exome public database was launched in November 2017 by the Key Laboratory of Modern Anthropology of the Ministry of Education of Fudan University in collaboration with iGeneTech company. It is the first whole-exome public database with the main purpose of sharing in China, whose architecture was designed by the research team of academician Jin Li in Fudan University. The AIwholeExome whole-exome capture chip, independently developed by iGeneTech, was used for sequence capture. At present, sequencing of all samples and data analysis of 5000 cases have been completed, which constitutes the first version of the whole-exome database by the research team of academician Jin Li in Fudan University. Full version of whole-exome database will be launched in 2020.