BEable-GPS: Base Editable prediction of Global Pathogenic-related SNVs

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BE	Cas	APOBEC	UGI	PAM	Editing window	Reference
BE3	nSpCas9	rA1	1	NGG	4-8	Komor et.al,2016
BE4max	nSpCas9	rA1	2	NGG	4-8	Koblan et.al,2018
YE1-BE3	nSpCas9	rA1W90Y/R126E	1	NGG	5-7	Kim et.al.,2017
YEE-BE3	nSpCas9	rA1W90Y/R126E/R132E	1	NGG	5-6	Kim et.al.,2017
VQR-BE3	nSpCas9(VQR)	rA1	1	NGAN	4-11	Kim et.al.,2017
VRER-BE3	nSpCas9(VRER)	rA1	1	NGCG	3-10	Kim et.al.,2017
SaBE3	nSaCas9	rA1	1	NNGRRT	3-12	Kim et.al.,2017
Sa(KKH)BE3	nSaCas9(KKH)	rA1	1	NNNRRT	3-12	Kim et.al.,2017
eBE-S3	nSpCas9	rA1	1+3Xfree	NNG	4-8	Wang et.al.,2017
dCpf1-eBE	dLbfCas12a	rA1	1+3Xfree	TTTV	8-13	Li et.al.,2018
dCpf1-eBE-YE	dLbfCas12a	rA1W90Y/R126E	1+3Xfree	TTTV	10-12	Li et.al.,2018
Target-AID	nSpCas9	CDA1	1	NGG	2-4	Nishida et.al.,2016
Target-AID-NG	nSpCas9(NG)	CDA1	1	NG	2-4	Nishimasu et.al.,2018
xBE3	xSpCas9	rA1	1	NG	4-8	Hu et.al.,2018
hA3A-eBE	nSpCas9	hA3A	1+3Xfree	NGG	2-13	Wang et.al.,2018
hA3A-eBE-Y130F	nSpCas9	hA3AY130F	1+3Xfree	NGG	3-8	Wang et.al.,2018
hA3A-eBE-Y132D	nSpCas9	hA3AY132D	1+3Xfree	NGG	3-7	Wang et.al.,2018
eA3A-BE3	nSpCas9	hA3AN37G	1	NGG	4-8(TC)	Gehrke et.al.,2018
BE3-R33A	nSpCas9	rA1R33A	1	NGG	5-7	Grunewald et.al.,2019
BE3-R33A/K34A	nSpCas9	rA1R33A/K34A	1	NGG	5-6(TC)	Grunewald et.al.,2019

Correcting pathogenic T-to-C mutation for disease treatment
Creating pathogenic C-to-T mutation for disease model