Disorder "Sepsis"
Found 39 records
Disorder information
Disorder name:
Sepsis
Disoder ID:
Synonyms:
Infection in blood stream
Definition:
Systemic inflammatory response to infection.
Modifier statisitcs
Record:
39
Gene:
38
Variant:
39
Reference:
1
Effect type:
Penetrance(39)
Modifier effect:
Altered incidence(39)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| UNC119 | UNC119:rs143353275 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| TRPC7 | TRPC7:c.314G-C(p.R105P) | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| TOLLIP | TOLLIP:rs144425237 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| TNK2 | TNK2:rs143787673 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| TLR10 | TLR10:rs145139818 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| TIMELESS | TIMELESS:rs776826265 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| TIAM1 | TIAM1:rs372955793 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| TACR3 | TACR3:rs201886341 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| RP1 | RP1:rs769522856 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| PRKCQ | PRKCQ:c.1885C-T(p.R629C) | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |