Disorder "Sepsis"
Found 39 records
Disorder information
Disorder name:
Sepsis
Disoder ID:
Synonyms:
Infection in blood stream
Definition:
Systemic inflammatory response to infection.
Modifier statisitcs
Record:
39
Gene:
38
Variant:
39
Reference:
1
Effect type:
Penetrance(39)
Modifier effect:
Altered incidence(39)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| ERBB3 | ERBB3:c.3396C-G(p.Y1132*) | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| ELOVL5 | ELOVL5:c.32A-G(p.Y11C) | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| EDNRB | EDNRB:rs200548885 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| DGKD | DGKD:rs139085833 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| BCAR1 | BCAR1:rs769793248 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| AP3S2 | AP3S2:c.203A-G(p.Y68C) | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| AGT | AGT:rs61731497 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| ADRA1D | ADRA1D:rs55926349 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| ACLY | ACLY:rs79062040 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |