Disorder "Sepsis"
Found 39 records
Disorder information
Disorder name:
Sepsis
Disoder ID:
Synonyms:
Infection in blood stream
Definition:
Systemic inflammatory response to infection.
Modifier statisitcs
Record:
39
Gene:
38
Variant:
39
Reference:
1
Effect type:
Penetrance(39)
Modifier effect:
Altered incidence(39)
| Modifier gene | Variant | Effect type | Modifier effect | Evidence | Effect | PubMed ID |
|---|---|---|---|---|---|---|
| P2RY2 | P2RY2:rs755037985 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| P2RY11 | P2RY11:rs200236974 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| NTSR2 | NTSR2:rs186016078 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| NOD1 | NOD1:c.689T-G(p.F230C) | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| NMS | NMS:rs368460081 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| NLRC4 | NLRC4:c.557G-A(p.W186*) | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| NLRC4:rs199475953 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more | |
| MTOR | MTOR:rs151082401 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| MESP1 | MESP1:rs771329728 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |
| MAP3K1 | MAP3K1:rs749900834 | Penetrance | Altered incidence | Identified by leave-one-out cross-validation (LOOCV)experiments | the putative protein damaging alleles may be protective in case of sepsismore | more |