Terguride

Basic Information

CAS ID: 37686-84-3
Molecular Formula: C20H28N4O
Molecular Weight: 340.5 g/mol
Monoisotopic Mass: 340.2263 g/mol
Class: Small Molecule
Natural Product: No
Other Names: TERGURIDE
Analysis: Drug repositioning mechanism analysis

N O NH NH N

Compound Structure and Identifier

InChI: InChI=1S/C20H28N4O/c1-4-24(5-2)20(25)22-14-10-16-15-7-6-8-17-19(15)13(11-21-17)9-18(16)23(3)12-14/h6-8,11,14,16,18,21H,4-5,9-10,12H2,1-3H3,(H,22,25)/t14-,16+,18+/m0/s1 See All
InChI Key: JOAHPSVPXZTVEP-YXJHDRRASA-N
Smiles: CCN(CC)C(=O)N[C@H]1C[C@H]2[C@@H](Cc3c[nH]c4cccc2c34)N(C)C1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0145 5-hydroxytryptamine receptor 2A antagonist
T0146 5-hydroxytryptamine receptor 2B antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 28821451 Target ID T0146
Uniprot ID 5-hydroxytryptamine receptor 2B Name 5-hydroxytryptamine receptor 2B
Model rat Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1 signaling

Reference Record 2

PubMed ID 28821451 Target ID T0145
Uniprot ID 5-hydroxytryptamine receptor 2A Name 5-hydroxytryptamine receptor 2A
Model rat Fibrosis Disease Pulmonary fibrosis
Process I attenue inflammation
Process II
Process III prevenet collagen deposition
Mechanism Targeting TGF-β1 signaling

Related Link

PubChem: 443951
ChEMBL: CHEMBL73151