Triciribine

Basic Information

CAS ID: 35943-35-2
Molecular Formula: C13H16N6O4
Molecular Weight: 320.3 g/mol
Monoisotopic Mass: 320.1233 g/mol
Class: Small Molecule
Natural Product: No
Other Names: NSC-154020
Analysis: Drug repositioning mechanism analysis

N N NH2 N O HO HO OH N N

Compound Structure and Identifier

InChI: InChI=1S/C13H16N6O4/c1-18-11-7-5(10(14)17-18)2-19(12(7)16-4-15-11)13-9(22)8(21)6(3-20)23-13/h2,4,6,8-9,13,20-22H,3H2,1H3,(H2,14,17)/t6-,8-,9-,13-/m1/s1 See All
InChI Key: HOGVTUZUJGHKPL-HTVVRFAVSA-N
Smiles: CN1N=C(N)c2cn([C@@H]3O[C@H](CO)[C@@H](O)[C@H]3O)c4ncnc1c24 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0360 RAC-alpha serine/threonine-protein kinase inhibitor
T0361 RAC-beta serine/threonine-protein kinase inhibitor
T0362 RAC-gamma serine/threonine-protein kinase inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 26033700 Target ID T0360
Uniprot ID RAC-alpha serine/threonine-protein kinase Name RAC-alpha serine/threonine-protein kinase
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 26033700 Target ID T0361
Uniprot ID RAC-beta serine/threonine-protein kinase Name RAC-beta serine/threonine-protein kinase
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 26033700 Target ID T0362
Uniprot ID RAC-gamma serine/threonine-protein kinase Name RAC-gamma serine/threonine-protein kinase
Model vitro,mice Fibrosis Disease Pulmonary fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 65399
ChEMBL: CHEMBL331237