RAC-gamma serine/threonine-protein kinase

Basic Information

Uniprot ID:	Q9Y243
Secondary ID:	Q0VAA6
Symbol:	AKT3
Other Name:	PKBG,Protein kinase Akt-3,Protein kinase B gamma,PKB gamma,RAC-PK-gamma,STK-2
Class:	Single Protein
Type:	pro-fibrotic
Molecular Function:	Kinase,Serine/threonine-protein kinase,Transferase

Target Classification

Category I	Category II	Category III
Intracellular	Enzyme	Kinase

Related Compound

Target ID	Name	Interaction
D0207	Triciribine	inhibitor
D0441	Akt Inhibitor VIII	inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID	26033700	Compound ID	D0207
CAS	35943-35-2	Name	Triciribine
Model	vitro,mice	Fibrosis Disease	Pulmonary fibrosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID	18323784	Compound ID	D0432
CAS	701976-54-7	Name	Akt Inhibitor II
Model	vitro	Fibrosis Disease	Systemic sclerosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID	18323784	Compound ID	D0441
CAS	612847-09-3	Name	Akt Inhibitor VIII
Model	vitro	Fibrosis Disease	Systemic sclerosis
Process I
Process II
Process III	prevenet collagen deposition
Mechanism