Spiperone

Basic Information

CAS ID: 749-02-0
Molecular Formula: C23H26FN3O2
Molecular Weight: 395.5 g/mol
Monoisotopic Mass: 395.2009 g/mol
Class: Small Molecule
Natural Product: No
Other Names: SPIROPITAN | SPIPERONE | R 5147
Analysis: Drug repositioning mechanism analysis

F O N N NH O

Compound Structure and Identifier

InChI: InChI=1S/C23H26FN3O2/c24-19-10-8-18(9-11-19)21(28)7-4-14-26-15-12-23(13-16-26)22(29)25-17-27(23)20-5-2-1-3-6-20/h1-3,5-6,8-11H,4,7,12-17H2,(H,25,29) See All
InChI Key: DKGZKTPJOSAWFA-UHFFFAOYSA-N
Smiles: Fc1ccc(cc1)C(=O)CCCN2CCC3(CC2)N(CNC3=O)c4ccccc4 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0145 5-hydroxytryptamine receptor 2A antagonist
T0146 5-hydroxytryptamine receptor 2B antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 21765932 Target ID
Uniprot ID Name
Model vitro Fibrosis Disease Cystic fibrosis
Process I
Process II
Process III
Mechanism Targeting PYK2

Reference Record 2

PubMed ID 16936262 Target ID T0145
Uniprot ID 5-hydroxytryptamine receptor 2A Name 5-hydroxytryptamine receptor 2A
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation,HSCs apoptosis
Process III
Mechanism

Reference Record 3

PubMed ID 16936262 Target ID T0146
Uniprot ID 5-hydroxytryptamine receptor 2B Name 5-hydroxytryptamine receptor 2B
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation,HSCs apoptosis
Process III
Mechanism

Related Link

PubChem: 5265
ChEMBL: CHEMBL267930