Akt Inhibitor II

Basic Information

CAS ID: 701976-54-7
Molecular Formula: C29H59O10P
Molecular Weight: 598.8 g/mol
Monoisotopic Mass: 598.3846 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

O O P O OH O HO HO OH O O

Compound Structure and Identifier

InChI: InChI=1S/C29H59O10P/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-37-22-24(35-2)23-38-40(33,34)39-29-26(36-3)21-25(30)27(31)28(29)32/h24-32H,4-23H2,1-3H3,(H,33,34)/t24-,25-,26-,27+,28-,29-/m1/s1 See All
InChI Key: NRLLDDPUQZQEDV-MWJQJBPESA-N
Smiles: CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)O[C@H]1[C@H](O)[C@@H](O)[C@H](O)C[C@H]1OC)OC See All
Molfile: Download

Related Target

Target ID Name Interaction
T0991 Protein kinase B inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 18495798 Target ID T0991
Uniprot ID Protein kinase B Name Protein kinase B
Model vitro,rat Fibrosis Disease Renal fibrosis
Process I
Process II EMT
Process III
Mechanism Targeting PKB/Akt signaling

Reference Record 2

PubMed ID 18323784 Target ID T0360
Uniprot ID RAC-alpha serine/threonine-protein kinase Name RAC-alpha serine/threonine-protein kinase
Model vitro Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 3

PubMed ID 18323784 Target ID T0361
Uniprot ID RAC-beta serine/threonine-protein kinase Name RAC-beta serine/threonine-protein kinase
Model vitro Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 4

PubMed ID 18323784 Target ID T0362
Uniprot ID RAC-gamma serine/threonine-protein kinase Name RAC-gamma serine/threonine-protein kinase
Model vitro Fibrosis Disease Systemic sclerosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 9938589
ChEMBL: CHEMBL452304