Metitepine

Basic Information

CAS ID: 20229-30-5
Molecular Formula: C20H24N2S2
Molecular Weight: 356.6 g/mol
Monoisotopic Mass: 356.1381 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Methiothepin Mesylate | Metitepine | METHIOTHEPIN
Analysis: Drug repositioning mechanism analysis

S S N N

Compound Structure and Identifier

InChI: InChI=1S/C20H24N2S2/c1-21-9-11-22(12-10-21)18-13-15-5-3-4-6-19(15)24-20-8-7-16(23-2)14-17(18)20/h3-8,14,18H,9-13H2,1-2H3 See All
InChI Key: RLJFTICUTYVZDG-UHFFFAOYSA-N
Smiles: CSc1ccc2Sc3ccccc3CC(N4CCN(C)CC4)c2c1 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0145 5-hydroxytryptamine receptor 2A antagonist
T0146 5-hydroxytryptamine receptor 2B antagonist

Related Fibrosis Property

Reference Record 1

PubMed ID 16936262 Target ID T0146
Uniprot ID 5-hydroxytryptamine receptor 2B Name 5-hydroxytryptamine receptor 2B
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation,HSCs apoptosis
Process III
Mechanism

Reference Record 2

PubMed ID 16936262 Target ID T0145
Uniprot ID 5-hydroxytryptamine receptor 2A Name 5-hydroxytryptamine receptor 2A
Model vitro Fibrosis Disease Liver fibrosis
Process I
Process II HSCs proliferation,HSCs apoptosis
Process III
Mechanism

Related Link

PubChem: 4106
ChEMBL: CHEMBL93240