Wortmannin

Basic Information

CAS ID: 19545-26-7
Molecular Formula: C23H24O8
Molecular Weight: 428.4 g/mol
Monoisotopic Mass: 428.1471 g/mol
Class: Small Molecule
Natural Product: No
Other Names: Wortmannin
Analysis: Drug repositioning mechanism analysis

O O O O O O O O

Compound Structure and Identifier

InChI: InChI=1S/C23H24O8/c1-10(24)30-13-7-22(2)12(5-6-14(22)25)16-18(13)23(3)15(9-28-4)31-21(27)11-8-29-20(17(11)23)19(16)26/h8,12-13,15H,5-7,9H2,1-4H3/t12-,13+,15+,22-,23-/m0/s1 See All
InChI Key: QDLHCMPXEPAAMD-QAIWCSMKSA-N
Smiles: COC[C@H]1OC(=O)c2coc3C(=O)C4=C([C@@H](C[C@@]5(C)[C@H]4CCC5=O)OC(=O)C)[C@]1(C)c23 See All
Molfile: Download

Related Target

Target ID Name Interaction
T0232 Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform inhibitor

Related Fibrosis Property

Reference Record 1

PubMed ID 16841034 Target ID T0232
Uniprot ID Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Name Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Model vitro Fibrosis Disease Keloid
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 16289155 Target ID T0383
Uniprot ID Dual specificity mitogen-activated protein kinase kinase 1 Name Dual specificity mitogen-activated protein kinase kinase 1
Model vitro Fibrosis Disease Keloid
Process I
Process II
Process III
Mechanism

Reference Record 3

PubMed ID 16289155 Target ID T0384
Uniprot ID Dual specificity mitogen-activated protein kinase kinase 2 Name Dual specificity mitogen-activated protein kinase kinase 2
Model vitro Fibrosis Disease Keloid
Process I
Process II
Process III
Mechanism

Related Link

PubChem: 312145
ChEMBL: CHEMBL428496