GW3965

Basic Information

CAS ID: 405911-17-3
Molecular Formula: C33H32Cl2F3NO3
Molecular Weight: 618.5 g/mol
Monoisotopic Mass: 617.171 g/mol
Class: Small Molecule
Natural Product: No
Other Names:
Analysis: Drug repositioning mechanism analysis

N O O OH F F F Cl HCl

Compound Structure and Identifier

InChI: InChI=1S/C33H31ClF3NO3.ClH/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26;/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40);1H See All
InChI Key: NMPUWJFHNOUNQU-UHFFFAOYSA-N
Smiles: C1=CC=C(C=C1)C(CN(CCCOC2=CC=CC(=C2)CC(=O)O)CC3=C(C(=CC=C3)C(F)(F)F)Cl)C4=CC=CC=C4.Cl See All
Molfile: Download

Related Target

Target ID Name Interaction
T0532 Oxysterols receptor LXR-alpha agonist
T0533 Oxysterols receptor LXR-beta agonist

Related Fibrosis Property

Reference Record 1

PubMed ID 26667495 Target ID T0533
Uniprot ID Oxysterols receptor LXR-beta Name Oxysterols receptor LXR-beta
Model mice Fibrosis Disease Arteriolar fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Reference Record 2

PubMed ID 26667495 Target ID T0532
Uniprot ID Oxysterols receptor LXR-alpha Name Oxysterols receptor LXR-alpha
Model mice Fibrosis Disease Arteriolar fibrosis
Process I
Process II
Process III prevenet collagen deposition
Mechanism

Related Link

PubChem: 16078973
ChEMBL: