Non-lysosomal glucosylceramidase

Basic Information

Uniprot ID: Q9HCG7
Secondary ID: D3DRP2
Symbol: GBA2
Other Name: KIAA1605,NLGase,Beta-glucocerebrosidase 2,Beta-glucosidase 2,Glucosylceramidase 2
Class: Single Protein
Type: pro-fibrotic
Molecular Function: Glycosidase,Hydrolase

Target Classification

Category I Category II Category III
Intracellular Enzyme Hydrolase

Related Compound

Target ID Name Interaction
D0203 Miglustat inhibitor
D0254 Genz-529648 inhibitor

Fibrosis Related Property

Reference Record 1

PubMed ID 25141135 Compound ID D0203
CAS 72599-27-0 Name Miglustat
Model vitro Fibrosis Disease Cystic fibrosis
Process I attenue inflammation
Process II
Process III
Mechanism

Reference Record 2

PubMed ID 25141135 Compound ID D0254
CAS 216758-20-2 Name Genz-529648
Model vitro Fibrosis Disease Cystic fibrosis
Process I attenue inflammation
Process II
Process III
Mechanism