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General Information
GT Name
UDP-GlcNAc: ursodeoxycholic acid β-N-acetylglucosaminyltransferase (UGT3A1;LOC133688)
Genbank Accession
AAH35012.1    AAH68446.1    ABA67139.1    ABE15394.1    BAB71358.1   
BAC03783.1    BAF83498.1    BAF98742.1    BAH12266.1    BAH14044.1   
CAC42674.1    CAD23353.1    NP_689617.2
Uniprot Accession
A8K444    Q6NUS8
Organism
Homo sapiens
Classification
eukaryota
Expression Status
Subcellular Location
 
Membrane ; Single-pass membrane protein . [A8K444]
Membrane ; Single-pass type I membrane protein . [Q6NUS8]
Catalytic Activity
Mechanism
Inverting
EC
2.4.1.-
Reaction

1) glucuronate acceptor + UDP-alpha-D-glucuronate = acceptor beta-D-glucuronoside + H(+) + UDP [A8K444  Q6NUS8]

Functional Annotation
GO
Cellular Component
Molecular Function
Pathway DIAMOND
Protein Family
GT Family
GT1
Pfam Accession
PF00201, UDPGT
3D Structure Status
GT-B
Structure Information No data available.
Sequence Information
Genbank 
>AAH35012.1 UGT3A1 protein [Homo sapiens]
MLHQSGKFLIPDIKEEEKSYQVIRWFSPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIMDSL
KNENYDLVFVEAFDFCSFLIAEKLVKPFVAILPTTFGSLDFGLPSPLSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQ
WDMQSTFDNTIKEHFPEGSRPVLSHLLLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQNGQPALFTTPSLF
SSGVYPEPLRRL
CDS

All...

Uniprot 
>tr|A8K444|A8K444_HUMAN UDP-glucuronosyltransferase OS=Homo sapiens OX=9606 GN=UGT3A1 PE=2 SV=1
MVGQRVLLLVAFLLSGVLLSEAAKILTISTLGGSHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWF
SPEDHQKRIKKHFDSYIETALDGRKESEALVKLMEIFGTQCSYLLSRKDIMDSLKNENYDLVFVEAFDFCSFLIAEKLVK
PFVAILPTTFGSLDFGLPSPLSYVPVFPSLLTDHMDFWGRVKNFLMFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHL
LLKAELWFVNSDFAFDFARPLLPNTVYIGGLMEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLNTHQSQEVLKKMHNAF
AHLPQGVIWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNGDQHGNMVR
VVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVGWIDHILQTGGATHLKPYAFQQPW
HEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLRGARKVKKT

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References

1. Ota,T.,et al.Complete sequencing and characterization of 21,243 full-length human cDNAs.Nat. Genet. 36 (1), 40-45 (2004).14702039.

2. Strausberg RL,et al.Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.Proc. Natl. Acad. Sci. U.S.A. 99 (26), 16899-16903 (2002).12477932.

3. Mackenzie,P.I.,et al.Identification of UDP glycosyltransferase 3A1 as a UDP N-acetylglucosaminyltransferase.J. Biol. Chem. 283 (52), 36205-36210 (2008).18981171.

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