2. PATHOGENS
Basic Information
Accession number
GCA_000018445.1
Release date
2008-04-15
Organism
Acinetobacter baumannii ACICU
Species name
Acinetobacter baumannii
Assembly level
Complete Genome
Assembly name
ASM1844v1
Assembly submitter
CNR - National Research Council
Assembly Type
haploid
Genome size
4.0 Mb
GC percent
39.0
Contig count
3
Collection date
-
Sample location
-
Host
-
Isolation source
-
Isolate type
-
Strain
ACICU
Isolate
-
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
CP000863.1_160 # 180225 # 181013 200.0 374.785 ANT(3'')-IIc 68.99 ARO:3004091 protein homolog model aminoglycoside antibiotic antibiotic inactivation ANT(3'') ANT(3'')-IIc is a aminoglycoside nucleotidyltransferase identified in Acinetobacter spp. via horizontal gene transfer mechanisms.
CP000863.1_227 # 250782 # 251414 275.0 412.92 AAC(6')-Ib10 96.67 ARO:3002581 protein homolog model aminoglycoside antibiotic antibiotic inactivation AAC(6') AAC(6')-Ib10 is an integron-encoded aminoglycoside acetyltransferase in P. aeruginosa.
CP000863.1_229 # 251962 # 252762 500.0 551.977 OXA-20 100.0 ARO:3001415 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-20 is a beta-lactamase found in P. aeruginosa.
CP000863.1_230 # 253002 # 253349 190.0 219.55 qacEdelta1 100.0 ARO:3005010 protein homolog model disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump QacEdelta1 is a resistance gene conferring resistance to antiseptics. It is different from QacE only at the 3'-terminus.
CP000863.1_231 # 253343 # 254182 500.0 553.132 sul1 100.0 ARO:3000410 protein homolog model sulfonamide antibiotic antibiotic target replacement sulfonamide resistant sul Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons.
CP000863.1_409 # 445926 # 447272 850.0 887.1 abeM 99.78 ARO:3000753 protein homolog model fluoroquinolone antibiotic; disinfecting agents and antiseptics antibiotic efflux multidrug and toxic compound extrusion (MATE) transporter AbeM is an multidrug efflux pump found in Acinetobacter baumannii.
CP000863.1_446 # 488623 # 489723 700.0 741.11 LpsB 97.81 ARO:3005051 protein homolog model peptide antibiotic reduced permeability to antibiotic Intrinsic peptide antibiotic resistant Lps LpsB is involved in lipopolysaccharide synthesis. It confers intrinsic resistance to colistin and other peptide antibiotics.
CP000863.1_1156 # 1250942 # 1251196 100.0 102.064 rsmA 89.09 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
CP000863.1_1331 # 1435199 # 1436488 700.0 863.218 Acinetobacter baumannii AbaF 100.0 ARO:3004573 protein homolog model phosphonic acid antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Expression of abaF in E. coli resulted in increased resistance to fosfomycin.
CP000863.1_1559 # 1672369 # 1673193 500.0 566.614 OXA-66 100.0 ARO:3001615 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-66 is a beta-lactamase found in A. baumannii.
CP000863.1_1822 # 1946601 # 1947998 850.0 952.97 adeC 100.0 ARO:3003811 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeC is the outer membrane factor of the AdeABC multidrug efflux complex. It can be replaced by other outer membrane channels, and is not essential for antibiotic resistance.
CP000863.1_1823 # 1948075 # 1951185 2000.0 2091.62 adeB 100.0 ARO:3000775 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeB is the multidrug transporter of the adeABC efflux system.
CP000863.1_1824 # 1951182 # 1952372 750.0 802.357 adeA 100.0 ARO:3000774 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeA is the membrane fusion protein of the multidrug efflux complex AdeABC.
CP000863.1_1825 # 1952518 # 1953261 480.0 505.368 adeR 99.19 ARO:3000553 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeR is a positive regulator of AdeABC efflux system. AdeR inactivation leads to susceptibility to aminoglycoside antibiotics.
CP000863.1_1826 # 1953293 # 1954366 700.0 705.671 adeS 96.36 ARO:3000549 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeS is a sensor kinase in the AdeRS regulatory system of AdeABC. It is essential for AdeABC expression.
CP000863.1_1947 # 2083032 # 2084336 600.0 864.759 Acinetobacter baumannii AbaQ 100.0 ARO:3004574 protein homolog model fluoroquinolone antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AbaQ is an MFS transporter mainly involved in the extrusion of quinolone-type drugs in A. baumannii.
CP000863.1_2099 # 2239913 # 2240566 420.0 446.817 adeN 98.62 ARO:3000559 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeN is a repressor of AdeIJK, a RND-type efflux pump in Acinetobacter baumannii. Its inactivation increases expression of AdeJ.
CP000863.1_2248 # 2376438 # 2377916 600.0 964.14 Acinetobacter baumannii AmvA 98.98 ARO:3004577 protein homolog model macrolide antibiotic; disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AmvA has 14 alpha-helical transmembrane segments, qualifying it as a member of the DHA2 transporter family of the major facilitator superfamily (MFS). When AmvA was expressed in E. coli, the cells had at least four-fold decreased susceptibility to erythromycin, acridine orange, acriflavine, deoxycholate and methyl viologen. AmvA from the AC0037 strain of A. baumannii was tested.
CP000863.1_2492 # 2636203 # 2636532 175.0 209.92 abeS 100.0 ARO:3000768 protein homolog model macrolide antibiotic; aminocoumarin antibiotic antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump AbeS in an efflux pump of the SMR family of transporters found in Acinetobacter baumannii.
CP000863.1_2497 # 2639841 # 2640872 650.0 694.501 adeL 100.0 ARO:3000620 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeL is a regulator of AdeFGH in Acinetobacter baumannii. AdeL mutations are associated with AdeFGH overexpression and multidrug resistance.
CP000863.1_2498 # 2641070 # 2642290 800.0 818.15 adeG 100.0 ARO:3000778 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeG is the inner membrane transporter of the AdeFGH multidrug efflux complex.
CP000863.1_2499 # 2642297 # 2645476 750.0 2135.53 adeF 99.81 ARO:3000777 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH.
CP000863.1_2500 # 2645489 # 2646937 900.0 958.748 adeH 99.59 ARO:3000779 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeH is the outer membrane channel protein of the AdeFGH multidrug efflux complex.
CP000863.1_2558 # 2715809 # 2716939 700.0 758.059 ADC-175 99.46 ARO:3006347 protein homolog model cephalosporin antibiotic inactivation ADC beta-lactamases pending classification for carbapenemase activity ADC-175 is a ADC beta-lactamase.
CP000863.1_2977 # 3171149 # 3172399 800.0 832.787 adeI 100.0 ARO:3000780 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeI is the membrane fusion protein of the AdeIJK multidrug efflux complex.
CP000863.1_2978 # 3172412 # 3175588 2000.0 2149.4 adeJ 99.91 ARO:3000781 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeJ is a RND efflux protein that acts as the inner membrane transporter of the AdeIJK efflux complex. It has 57% identity with E. coli AcrB.
CP000863.1_2979 # 3175588 # 3177042 950.0 974.926 adeK 100.0 ARO:3000782 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeK is the outer membrane factor protein in the adeIJK multidrug efflux complex.
CP000864.1_20 # 13453 # 14226 500.0 534.643 OXA-58 100.0 ARO:3001611 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-58 is a beta-lactamase found in A. baumannii.
CP000864.1_25 # 17467 # 18240 500.0 534.643 OXA-58 100.0 ARO:3001611 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-58 is a beta-lactamase found in A. baumannii.
CP000863.1_218 # 240839 # 243058 1400.0 1502.26 Acinetobacter baumannii parC conferring resistance to fluoroquinolones 99.59 ARO:3003818 protein variant model V104I, D105E fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant parC Mutations in Acinetobacter baumannii parC that result in resistance to fluoroquinolones.
CP000863.1_2863 # 3027667 # 3030381 1500.0 1835.08 Acinetobacter baumannii gyrA conferring resistance to fluoroquinolones 99.78 ARO:3003817 protein variant model S81L fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant gyrA Mutations in the A subunit of DNA gyrase reduce its affinity for fluoroquinolones, thereby conferring resistance.
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
CP000863.1_68 100.0 0.0 plc1 VF0470 Phospholipase C Exotoxin VFC0235 (plc1) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_75 100.0 0.0 ACICU_RS00395 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00395) polysaccharide biosynthesis tyrosine autokinase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_76 100.0 6.62E-107 ACICU_RS00400 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00400) low molecular weight phosphotyrosine protein phosphatase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_77 100.0 0.0 ACICU_RS00405 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00405) polysaccharide biosynthesis/export family protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_78 100.0 0.0 tviB VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (tviB) Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_79 100.0 0.0 pseB VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pseB) UDP-N-acetylglucosamine 4,6-dehydratase (inverting) [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_80 100.0 0.0 pseC VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pseC) UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_81 100.0 7.21E-176 pseF VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pseF) pseudaminic acid cytidylyltransferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_82 99.713 0.0 pseG VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pseG) UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_83 100.0 9.2E-128 pseH VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pseH) UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_84 100.0 0.0 pseI VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pseI) pseudaminic acid synthase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_85 100.0 0.0 ACICU_RS00445 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00445) hypothetical protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_86 100.0 0.0 ACICU_RS00450 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00450) capsular polysaccharide synthesis protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_89 100.0 1.11E-145 ACICU_RS00460 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00460) hypothetical protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_90 100.0 0.0 ACICU_RS00465 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00465) hypothetical protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_92 100.0 2.46E-154 ACICU_RS00475 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00475) sugar transferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_93 100.0 0.0 galU VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galU) UTP--glucose-1-phosphate uridylyltransferase GalU [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_94 100.0 0.0 ACICU_RS00485 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00485) nucleotide sugar dehydrogenase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_95 100.0 0.0 pgi VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pgi) glucose-6-phosphate isomerase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_96 100.0 0.0 galE VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_97 100.0 0.0 ACICU_RS00500 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00500) phosphomannomutase/phosphoglucomutase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_115 100.0 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_140 100.0 6.83E-138 abaI VF0471 Quorom sensing Biofilm VFC0271 (abaI) N-acyl-L-homoserine lactone synthetase [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_142 100.0 0.0 abaR VF0471 Quorom sensing Biofilm VFC0271 (abaR) DNA-binding HTH domain-containing protein [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_193 100.0 0.0 tsaP VF1334 TFP Adherence VFC0001 (tsaP) LysM peptidoglycan-binding domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_259 100.0 0.0 pilR VF1334 TFP Adherence VFC0001 (pilR) sigma-54 dependent transcriptional regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_260 100.0 0.0 pilS VF1334 TFP Adherence VFC0001 (pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_262 100.0 0.0 pbpG VF0468 PbpG Immune modulation VFC0258 (pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_292 100.0 0.0 gspN VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspN) type II secretion system protein N [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_293 100.0 0.0 gspC VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspC) general secretion pathway protein C [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_294 100.0 0.0 gspD VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspD) general secretion pathway protein D [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_299 78.894 2.32E-101 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP000863.1_300 79.444 1.2E-103 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP000863.1_348 100.0 0.0 gspO/pilD VF1334 TFP Adherence VFC0001 (gspO/pilD) A24 family peptidase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_349 100.0 0.0 pilC VF1334 TFP Adherence VFC0001 (pilC) type II secretion system F family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_350 100.0 0.0 pilB VF1334 TFP Adherence VFC0001 (pilB) type IV-A pilus assembly ATPase PilB [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_386 100.0 0.0 gspF VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspF) general secretion pathway protein F [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_387 100.0 7.06E-147 gspG VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspG) general secretion pathway protein G [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_442 100.0 0.0 fimV VF1334 TFP Adherence VFC0001 (fimV) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_446 100.0 0.0 lpsB VF0466 LPS Immune modulation VFC0258 (lpsB) glycosyltransferase family 4 protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_447 100.0 0.0 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_493 67.021 6.67E-97 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
CP000863.1_515 100.0 0.0 pilF VF1334 TFP Adherence VFC0001 (pilF) type IV pilus biogenesis/stability protein PilW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_626 100.0 0.0 gspE1 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE1) general secretion pathway protein E [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_656 66.359 1.69E-98 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP000863.1_713 100.0 3.98E-173 bfmR VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_714 100.0 0.0 bfmS VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_826 78.894 2.32E-101 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP000863.1_827 79.444 1.2E-103 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP000863.1_855 100.0 0.0 pilU VF1334 TFP Adherence VFC0001 (pilU) PilT/PilU family type 4a pilus ATPase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_856 100.0 0.0 pilT VF1334 TFP Adherence VFC0001 (pilT) type IV pilus twitching motility protein PilT [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_879 100.0 0.0 ACICU_RS04565 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04565) LysR family transcriptional regulator [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_880 100.0 5.18E-129 ACICU_RS04570 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04570) sigma-70 family RNA polymerase sigma factor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_881 100.0 0.0 ACICU_RS04575 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04575) FecR domain-containing protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_882 99.903 0.0 ACICU_RS04580 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04580) TonB-dependent receptor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_883 100.0 0.0 ACICU_RS04585 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04585) transferrin-binding protein-like solute binding protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_884 99.795 0.0 ACICU_RS04590 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04590) porin family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_885 100.0 0.0 ACICU_RS04595 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04595) TonB family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_886 100.0 5.03E-147 hemO VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (hemO) biliverdin-producing heme oxygenase [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_887 100.0 1.2E-106 ACICU_RS04605 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04605) YbaN family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_888 100.0 1.17E-65 ACICU_RS04610 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04610) hypothetical protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_981 61.0 2.5E-34 ureA VF0050 Urease Stress survival VFC0282 (ureA) urease alpha subunit UreA [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
CP000863.1_984 60.052 3.34E-175 ureB VF0050 Urease Stress survival VFC0282 (ureB) urease beta subunit UreB, urea amidohydrolase [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
CP000863.1_987 61.421 8.95E-94 ureG VF0050 Urease Stress survival VFC0282 (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
CP000863.1_1001 100.0 0.0 ata VF1333 Ata Adherence VFC0001 (ata) trimeric autotransporter adhesin Ata [Ata (VF1333) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1121 78.256 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1249 66.23 1.07E-156 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1260 100.0 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1295 100.0 4.65E-120 tssB VF1337 T6SS Effector delivery system VFC0086 (tssB) type VI secretion system contractile sheath small subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1296 100.0 0.0 tssC VF1337 T6SS Effector delivery system VFC0086 (tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1297 100.0 5.53E-126 hcp/tssD VF1337 T6SS Effector delivery system VFC0086 (hcp/tssD) type VI secretion system tube protein Hcp [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1298 100.0 2.59E-116 tssE VF1337 T6SS Effector delivery system VFC0086 (tssE) type VI secretion system baseplate subunit TssE [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1299 100.0 0.0 tssF VF1337 T6SS Effector delivery system VFC0086 (tssF) type VI secretion system baseplate subunit TssF [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1300 100.0 0.0 tssG VF1337 T6SS Effector delivery system VFC0086 (tssG) type VI secretion system baseplate subunit TssG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1302 100.0 0.0 tssM VF1337 T6SS Effector delivery system VFC0086 (tssM) type VI secretion system membrane subunit TssM [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1306 100.0 0.0 clpV/tssH VF1337 T6SS Effector delivery system VFC0086 (clpV/tssH) type VI secretion system ATPase TssH [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1307 100.0 0.0 tssA VF1337 T6SS Effector delivery system VFC0086 (tssA) type VI secretion system protein TssA [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1308 100.0 0.0 tssK VF1337 T6SS Effector delivery system VFC0086 (tssK) type VI secretion system baseplate subunit TssK [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1309 100.0 0.0 tssL VF1337 T6SS Effector delivery system VFC0086 (tssL) type IVB secretion system protein TssL [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1311 100.0 0.0 tagX VF1337 T6SS Effector delivery system VFC0086 (tagX) type VI-associated gene X, peptidoglycan hydrolase [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1534 60.816 4.42E-101 CBU_1566 VF0696 T4SS secreted effectors Effector delivery system VFC0086 (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] Coxiella burnetii
CP000863.1_1607 100.0 3.61E-137 gspH VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspH) general secretion pathway protein H [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1608 100.0 2.76E-91 gspI VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspI) general secretion pathway protein I [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1610 100.0 0.0 gspK VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspK) general secretion pathway protein K [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1696 100.0 0.0 lpxB VF0466 LPS Immune modulation VFC0258 (lpxB) lipid-A-disaccharide synthase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_1930 84.661 0.0 katA VF0454 KatA Stress survival VFC0282 (katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58] Neisseria meningitidis
CP000863.1_2004 61.429 2.0E-131 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
CP000863.1_2085 100.0 0.0 lpxA VF0466 LPS Immune modulation VFC0258 (lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2087 100.0 0.0 lpxD VF0466 LPS Immune modulation VFC0258 (lpxD) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2245 100.0 0.0 plc2 VF0470 Phospholipase C Exotoxin VFC0235 (plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2357 100.0 7.33E-113 pgaD VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaD) poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2358 100.0 0.0 pgaC VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2359 100.0 0.0 pgaB VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaB) poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2408 100.0 0.0 csuE VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuE) Csu pilus tip adhesin CsuE [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2409 100.0 0.0 csuD VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuD) Csu pilus usher protein CsuD [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2410 100.0 0.0 csuC VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2411 100.0 3.75E-127 csuB VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuB) Csu pilus subunit CsuB [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2414 100.0 9.77E-129 csuA/B VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuA/B) Csu pilus major pilin subunit CsuA/B [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2450 100.0 1.73E-114 gspM VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspM) general secretion pathway protein M [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2451 100.0 0.0 gspL VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspL) general secretion pathway protein L [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2484 100.0 0.0 gspE2 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2498 100.0 0.0 adeF VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeF) membrane-fusion protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2499 100.0 0.0 adeG VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2500 100.0 0.0 adeH VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2538 62.944 1.11E-87 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
CP000863.1_2564 100.0 0.0 basJ VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basJ) acinetobactin biosynthesis protein BasJ [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2565 100.0 0.0 basI VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basI) phosphopantetheinyl transferase component of acinetobactin biosynthesis protein BasI [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2566 100.0 0.0 basH VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basH) non-ribosomal peptide biosynthesis thioesterase BasH [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2567 100.0 0.0 barB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barB) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2568 100.0 0.0 barA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barA) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2570 100.0 0.0 basG VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2571 100.0 0.0 basF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basF) aryl carrier protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2572 100.0 0.0 entE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (entE) non-ribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2573 100.0 0.0 basD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basD) acinetobactin biosynthesis protein BasD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2574 100.0 0.0 basC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basC) acinetobactin biosynthesis protein BasC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2575 100.0 0.0 bauA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauA) TonB-dependent siderophore receptor BauA [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2576 100.0 0.0 bauB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauB) ferric siderophore ABC transporter, periplasmic siderophore-binding protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2577 100.0 0.0 bauE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauE) ferric siderophore ABC transporter, ATP-binding protein BauE [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2578 100.0 0.0 bauC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauC) ferric siderophore ABC transporter, permease protein BauC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2579 100.0 0.0 bauD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauD) ferric siderophore ABC transporter, permease protein BauD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2582 100.0 0.0 basB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basB) non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2583 100.0 0.0 basA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basA) acinetobactin biosynthesis protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2584 100.0 0.0 bauF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauF) siderophore-interacting protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2846 100.0 0.0 lpxM VF0466 LPS Immune modulation VFC0258 (lpxM) lysophospholipid acyltransferase family protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2900 73.004 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
CP000863.1_2930 99.951 0.0 bap VF0462 Bap Biofilm VFC0271 A large cell surface protein comprised of multiple copies of repeat elements; Bap homologues have also been identified and characterized in other bacteria, including members of other genera typically associated with hospital-acquired infection, such as Staphylococcus, Enterococcus, and Pseudomonas (bap) biofilm-associated protein [Bap (VF0462) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2931 81.25 3.42E-29 bap VF0462 Bap Biofilm VFC0271 A large cell surface protein comprised of multiple copies of repeat elements; Bap homologues have also been identified and characterized in other bacteria, including members of other genera typically associated with hospital-acquired infection, such as Staphylococcus, Enterococcus, and Pseudomonas (bap) biofilm-associated protein [Bap (VF0462) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_2932 77.778 1.96E-49 bap VF0462 Bap Biofilm VFC0271 A large cell surface protein comprised of multiple copies of repeat elements; Bap homologues have also been identified and characterized in other bacteria, including members of other genera typically associated with hospital-acquired infection, such as Staphylococcus, Enterococcus, and Pseudomonas (bap) biofilm-associated protein [Bap (VF0462) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3049 100.0 0.0 pilJ VF1334 TFP Adherence VFC0001 (pilJ) methyl-accepting chemotaxis protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3050 100.0 4.53E-135 pilI VF1334 TFP Adherence VFC0001 (pilI) chemotaxis protein CheW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3051 100.0 1.26E-86 pilH VF1334 TFP Adherence VFC0001 (pilH) response regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3052 100.0 9.66E-94 pilG VF1334 TFP Adherence VFC0001 (pilG) twitching motility response regulator PilG [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3078 100.0 0.0 ompA VF0464 OmpA Immune modulation VFC0258 (ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3079 100.0 1.11E-127 fimT VF1334 TFP Adherence VFC0001 (fimT) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3179 100.0 0.0 plcD VF0469 Phospholipase D Exotoxin VFC0235 (plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3352 100.0 8.32E-104 pilE VF1334 TFP Adherence VFC0001 (pilE) type IV pilin protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3353 100.0 1.95E-118 ACICU_RS16840 VF1334 TFP Adherence VFC0001 (ACICU_RS16840) prepilin-type N-terminal cleavage/methylation domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3354 100.0 0.0 pilY1 VF1334 TFP Adherence VFC0001 (pilY1) VWA domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3355 100.0 0.0 pilX VF1334 TFP Adherence VFC0001 (pilX) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3356 100.0 0.0 pilW VF1334 TFP Adherence VFC0001 (pilW) PilW family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3357 100.0 3.74E-138 pilV VF1334 TFP Adherence VFC0001 (pilV) type IV pilus modification protein PilV [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3358 100.0 1.53E-111 fimU VF1334 TFP Adherence VFC0001 (fimU) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3368 100.0 9.35E-103 pilA VF1334 TFP Adherence VFC0001 (pilA) pilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3378 100.0 0.0 pilQ VF1334 TFP Adherence VFC0001 (pilQ) type IV pilus secretin PilQ [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3379 100.0 2.48E-129 pilP VF1334 TFP Adherence VFC0001 (pilP) pilus assembly protein PilP [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3380 100.0 0.0 pilO VF1334 TFP Adherence VFC0001 (pilO) type 4a pilus biogenesis protein PilO [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3381 100.0 1.36E-161 pilN VF1334 TFP Adherence VFC0001 (pilN) PilN domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3382 100.0 0.0 pilM VF1334 TFP Adherence VFC0001 (pilM) pilus assembly protein PilM [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3515 100.0 0.0 lpxC VF0466 LPS Immune modulation VFC0258 (lpxC) UDP-3-O-acyl-N-acetylglucosamine deacetylase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP000863.1_3550 100.0 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii