2. PATHOGENS
Basic Information
Accession number
GCA_000021245.2
Release date
2017-06-27
Organism
Acinetobacter baumannii AB0057
Species name
Acinetobacter baumannii
Assembly level
Complete Genome
Assembly name
ASM2124v2
Assembly submitter
Case Western Reserve University
Assembly Type
haploid
Genome size
4.1 Mb
GC percent
39.0
Contig count
2
Collection date
-
Sample location
-
Host
-
Isolation source
-
Isolate type
-
Strain
AB0057
Isolate
-
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
CP001182.2_9 # 7866 # 9032 700.0 795.423 ADC-176 100.0 ARO:3006348 protein homolog model cephalosporin antibiotic inactivation ADC beta-lactamases pending classification for carbapenemase activity ADC-176 is a ADC beta-lactamase.
CP001182.2_166 # 190623 # 191411 200.0 374.015 ANT(3'')-IIc 69.77 ARO:3004091 protein homolog model aminoglycoside antibiotic antibiotic inactivation ANT(3'') ANT(3'')-IIc is a aminoglycoside nucleotidyltransferase identified in Acinetobacter spp. via horizontal gene transfer mechanisms.
CP001182.2_256 # 283631 # 284470 500.0 553.132 sul1 100.0 ARO:3000410 protein homolog model sulfonamide antibiotic antibiotic target replacement sulfonamide resistant sul Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons.
CP001182.2_267 # 291954 # 293228 700.0 822.002 tet(A) 98.81 ARO:3000165 protein homolog model tetracycline antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump TetA is a tetracycline efflux pump found in many species of Gram-negative bacteria.
CP001182.2_270 # 297074 # 297733 400.0 465.692 catI 100.0 ARO:3002683 protein homolog model phenicol antibiotic antibiotic inactivation chloramphenicol acetyltransferase (CAT) catA1 (formerly in CARD as catI) is a chromosome and transposon-encoded variant of the cat gene found in Escherichia coli and Acinetobacter baumannii.
CP001182.2_274 # 302629 # 303489 500.0 591.267 TEM-1 100.0 ARO:3000873 protein homolog model monobactam; cephalosporin; penam; penem antibiotic inactivation TEM beta-lactamase TEM-1 is a broad-spectrum beta-lactamase found in many Gram-negative bacteria. Confers resistance to penicillins and first generation cephalosphorins.
CP001182.2_278 # 309263 # 310078 500.0 565.459 APH(3')-Ia 100.0 ARO:3002641 protein homolog model aminoglycoside antibiotic antibiotic inactivation APH(3') APH(3')-Ia is a transposon-encoded aminoglycoside phosphotransferase in E. coli and S. enterica. It is identical at the protein sequence to APH(3')-Ic, an aminoglycoside phosphotransferase encoded by plasmids, transposons and genomic islands in K. pneumoniae, A. baumannii, S. marcescens, Corynebacterium spp., Photobacterium spp. and Citrobacter spp.
CP001182.2_281 # 312619 # 313152 300.0 313.153 AAC(3)-Ia 98.7 ARO:3002528 protein homolog model aminoglycoside antibiotic antibiotic inactivation AAC(3) AAC(3)-Ia is an aminoglycoside acetyltransferase encoded by plasmids, transposons, integrons in S. marcescens, E. coli, Acinetobacter baumannii, Klebsiella pneumoniae, Klebsiella oxytoca, P. aeruginosa, Salmonella typhimurium and Proteus mirabilis.
CP001182.2_283 # 314208 # 314987 450.0 519.62 ANT(3'')-IIa 99.61 ARO:3004089 protein homolog model aminoglycoside antibiotic antibiotic inactivation ANT(3'') ANT(3'')-IIa is a aminoglycoside nucleotidyltransferase identified in Acinetobacter spp. via horizontal gene transfer mechanisms.
CP001182.2_284 # 315151 # 315498 190.0 219.55 qacEdelta1 100.0 ARO:3005010 protein homolog model disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump QacEdelta1 is a resistance gene conferring resistance to antiseptics. It is different from QacE only at the 3'-terminus.
CP001182.2_285 # 315492 # 316331 500.0 553.132 sul1 100.0 ARO:3000410 protein homolog model sulfonamide antibiotic antibiotic target replacement sulfonamide resistant sul Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons.
CP001182.2_461 # 508015 # 509361 850.0 886.33 abeM 99.55 ARO:3000753 protein homolog model fluoroquinolone antibiotic; disinfecting agents and antiseptics antibiotic efflux multidrug and toxic compound extrusion (MATE) transporter AbeM is an multidrug efflux pump found in Acinetobacter baumannii.
CP001182.2_496 # 549631 # 550731 700.0 743.421 LpsB 98.09 ARO:3005051 protein homolog model peptide antibiotic reduced permeability to antibiotic Intrinsic peptide antibiotic resistant Lps LpsB is involved in lipopolysaccharide synthesis. It confers intrinsic resistance to colistin and other peptide antibiotics.
CP001182.2_537 # 585563 # 586384 500.0 565.459 OXA-23 100.0 ARO:3001418 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-23 is a beta-lactamase found in A. baumannii.
CP001182.2_1186 # 1312789 # 1313043 100.0 102.064 rsmA 89.09 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
CP001182.2_1472 # 1596955 # 1598244 700.0 860.907 Acinetobacter baumannii AbaF 99.77 ARO:3004573 protein homolog model phosphonic acid antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Expression of abaF in E. coli resulted in increased resistance to fosfomycin.
CP001182.2_1706 # 1844595 # 1845419 500.0 567.77 OXA-69 100.0 ARO:3001617 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-69 is a beta-lactamase found in A. baumannii.
CP001182.2_2033 # 2157543 # 2158940 850.0 932.169 adeC 97.2 ARO:3003811 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeC is the outer membrane factor of the AdeABC multidrug efflux complex. It can be replaced by other outer membrane channels, and is not essential for antibiotic resistance.
CP001182.2_2034 # 2159017 # 2162127 2000.0 2082.37 adeB 99.52 ARO:3000775 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeB is the multidrug transporter of the adeABC efflux system.
CP001182.2_2035 # 2162124 # 2163314 750.0 797.349 adeA 98.99 ARO:3000774 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeA is the membrane fusion protein of the multidrug efflux complex AdeABC.
CP001182.2_2036 # 2163460 # 2164203 480.0 508.064 adeR 100.0 ARO:3000553 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeR is a positive regulator of AdeABC efflux system. AdeR inactivation leads to susceptibility to aminoglycoside antibiotics.
CP001182.2_2037 # 2164235 # 2165320 700.0 734.947 adeS 99.72 ARO:3000549 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeS is a sensor kinase in the AdeRS regulatory system of AdeABC. It is essential for AdeABC expression.
CP001182.2_2126 # 2255585 # 2256889 600.0 864.759 Acinetobacter baumannii AbaQ 100.0 ARO:3004574 protein homolog model fluoroquinolone antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AbaQ is an MFS transporter mainly involved in the extrusion of quinolone-type drugs in A. baumannii.
CP001182.2_2272 # 2409530 # 2410183 420.0 448.743 adeN 99.08 ARO:3000559 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeN is a repressor of AdeIJK, a RND-type efflux pump in Acinetobacter baumannii. Its inactivation increases expression of AdeJ.
CP001182.2_2323 # 2464197 # 2465675 600.0 969.148 Acinetobacter baumannii AmvA 100.0 ARO:3004577 protein homolog model macrolide antibiotic; disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AmvA has 14 alpha-helical transmembrane segments, qualifying it as a member of the DHA2 transporter family of the major facilitator superfamily (MFS). When AmvA was expressed in E. coli, the cells had at least four-fold decreased susceptibility to erythromycin, acridine orange, acriflavine, deoxycholate and methyl viologen. AmvA from the AC0037 strain of A. baumannii was tested.
CP001182.2_2340 # 2480776 # 2481597 500.0 565.459 OXA-23 100.0 ARO:3001418 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-23 is a beta-lactamase found in A. baumannii.
CP001182.2_2595 # 2748233 # 2748562 175.0 209.92 abeS 100.0 ARO:3000768 protein homolog model macrolide antibiotic; aminocoumarin antibiotic antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump AbeS in an efflux pump of the SMR family of transporters found in Acinetobacter baumannii.
CP001182.2_2601 # 2751871 # 2752902 650.0 692.575 adeL 99.7 ARO:3000620 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeL is a regulator of AdeFGH in Acinetobacter baumannii. AdeL mutations are associated with AdeFGH overexpression and multidrug resistance.
CP001182.2_2602 # 2753100 # 2754320 800.0 818.15 adeG 100.0 ARO:3000778 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeG is the inner membrane transporter of the AdeFGH multidrug efflux complex.
CP001182.2_2603 # 2754327 # 2757506 750.0 2139.38 adeF 100.0 ARO:3000777 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH.
CP001182.2_2604 # 2757519 # 2758967 900.0 962.6 adeH 99.79 ARO:3000779 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeH is the outer membrane channel protein of the AdeFGH multidrug efflux complex.
CP001182.2_2741 # 2877549 # 2878700 700.0 787.334 ADC-11 100.0 ARO:3004615 protein homolog model cephalosporin antibiotic inactivation ADC beta-lactamase without carbapenemase activity ADC-11 is a class C beta-lactamase found in Acinetobacter baumannii.
CP001182.2_3078 # 3283427 # 3284677 800.0 832.787 adeI 100.0 ARO:3000780 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeI is the membrane fusion protein of the AdeIJK multidrug efflux complex.
CP001182.2_3079 # 3284690 # 3287866 2000.0 2149.4 adeJ 99.91 ARO:3000781 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeJ is a RND efflux protein that acts as the inner membrane transporter of the AdeIJK efflux complex. It has 57% identity with E. coli AcrB.
CP001182.2_3080 # 3287866 # 3289320 950.0 974.926 adeK 100.0 ARO:3000782 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeK is the outer membrane factor protein in the adeIJK multidrug efflux complex.
CP001182.2_223 # 250587 # 252806 1400.0 1509.2 Acinetobacter baumannii parC conferring resistance to fluoroquinolones 100.0 ARO:3003818 protein variant model S84L, V104I, D105E fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant parC Mutations in Acinetobacter baumannii parC that result in resistance to fluoroquinolones.
CP001182.2_2968 # 3134316 # 3137030 1500.0 1835.08 Acinetobacter baumannii gyrA conferring resistance to fluoroquinolones 99.78 ARO:3003817 protein variant model S81L fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant gyrA Mutations in the A subunit of DNA gyrase reduce its affinity for fluoroquinolones, thereby conferring resistance.
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
CP001182.2_82 97.23 0.0 plc1 VF0470 Phospholipase C Exotoxin VFC0235 (plc1) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_89 93.269 0.0 ACICU_RS00395 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00395) polysaccharide biosynthesis tyrosine autokinase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_90 90.845 3.9E-98 ACICU_RS00400 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00400) low molecular weight phosphotyrosine protein phosphatase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_91 91.257 0.0 ACICU_RS00405 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00405) polysaccharide biosynthesis/export family protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_92 79.009 0.0 tviB VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (tviB) Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_93 65.689 2.58E-174 tviC VF0101 Vi antigen Immune modulation VFC0258 Vi is abbreviation for virulence; the viaB locus is within Salmonella pathogenicity island SPI-7, which also encodes SopE and a type IVB pilus; The viaB locus encodes genes involved in regulation (tviA), Vi biosynthesis (tviBCDE), export, and retention of the Vi on the bacterial cell surface (vexABCDE); A viaB locus is absent from S. Paratyphi A, and most gastroenteritis-causing serovars including S. Typhimurium (tviC) Vi polysaccharide biosynthesis protein, UDP-GlcNAcA 4-epimerase TviC [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18] Salmonella enterica (serovar typhi)
CP001182.2_104 89.911 0.0 galE VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_107 94.502 0.0 galU VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galU) UTP--glucose-1-phosphate uridylyltransferase GalU [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_108 92.619 0.0 ACICU_RS00485 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00485) nucleotide sugar dehydrogenase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_109 93.885 0.0 pgi VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pgi) glucose-6-phosphate isomerase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_110 99.112 0.0 galE VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_111 99.123 0.0 ACICU_RS00500 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00500) phosphomannomutase/phosphoglucomutase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_146 99.454 1.79E-137 abaI VF0471 Quorom sensing Biofilm VFC0271 (abaI) N-acyl-L-homoserine lactone synthetase [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_148 98.739 4.95E-180 abaR VF0471 Quorom sensing Biofilm VFC0271 (abaR) DNA-binding HTH domain-containing protein [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_198 98.958 0.0 tsaP VF1334 TFP Adherence VFC0001 (tsaP) LysM peptidoglycan-binding domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_313 100.0 0.0 pilR VF1334 TFP Adherence VFC0001 (pilR) sigma-54 dependent transcriptional regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_314 100.0 0.0 pilS VF1334 TFP Adherence VFC0001 (pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_316 99.701 0.0 pbpG VF0468 PbpG Immune modulation VFC0258 (pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_346 99.595 0.0 gspN VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspN) type II secretion system protein N [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_347 99.281 0.0 gspC VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspC) general secretion pathway protein C [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_348 100.0 0.0 gspD VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspD) general secretion pathway protein D [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_352 78.173 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP001182.2_398 97.902 0.0 gspO/pilD VF1334 TFP Adherence VFC0001 (gspO/pilD) A24 family peptidase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_399 100.0 0.0 pilC VF1334 TFP Adherence VFC0001 (pilC) type II secretion system F family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_400 99.649 0.0 pilB VF1334 TFP Adherence VFC0001 (pilB) type IV-A pilus assembly ATPase PilB [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_437 99.751 0.0 gspF VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspF) general secretion pathway protein F [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_438 98.964 3.47E-145 gspG VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspG) general secretion pathway protein G [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_492 96.916 0.0 fimV VF1334 TFP Adherence VFC0001 (fimV) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_496 99.18 0.0 lpsB VF0466 LPS Immune modulation VFC0258 (lpsB) glycosyltransferase family 4 protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_497 99.035 0.0 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_565 67.021 6.67E-97 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
CP001182.2_587 98.872 0.0 pilF VF1334 TFP Adherence VFC0001 (pilF) type IV pilus biogenesis/stability protein PilW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_699 99.798 0.0 gspE1 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE1) general secretion pathway protein E [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_729 66.359 1.69E-98 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP001182.2_771 100.0 3.98E-173 bfmR VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_772 99.636 0.0 bfmS VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_885 78.173 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
CP001182.2_914 99.731 0.0 pilU VF1334 TFP Adherence VFC0001 (pilU) PilT/PilU family type 4a pilus ATPase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_915 99.71 0.0 pilT VF1334 TFP Adherence VFC0001 (pilT) type IV pilus twitching motility protein PilT [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_954 97.973 0.0 ACICU_RS04565 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04565) LysR family transcriptional regulator [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_955 98.266 4.12E-126 ACICU_RS04570 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04570) sigma-70 family RNA polymerase sigma factor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_956 97.633 0.0 ACICU_RS04575 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04575) FecR domain-containing protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_957 97.679 0.0 ACICU_RS04580 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04580) TonB-dependent receptor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_958 99.24 0.0 ACICU_RS04585 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04585) transferrin-binding protein-like solute binding protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_959 96.311 0.0 ACICU_RS04590 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04590) porin family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_960 93.137 0.0 ACICU_RS04595 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04595) TonB family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_961 99.495 1.88E-146 hemO VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (hemO) biliverdin-producing heme oxygenase [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_962 100.0 1.2E-106 ACICU_RS04605 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04605) YbaN family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_963 100.0 1.17E-65 ACICU_RS04610 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04610) hypothetical protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1056 61.0 2.5E-34 ureA VF0050 Urease Stress survival VFC0282 (ureA) urease alpha subunit UreA [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
CP001182.2_1061 61.421 8.95E-94 ureG VF0050 Urease Stress survival VFC0282 (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
CP001182.2_1119 78.364 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1391 65.902 3.81E-156 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1401 91.775 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1436 100.0 4.65E-120 tssB VF1337 T6SS Effector delivery system VFC0086 (tssB) type VI secretion system contractile sheath small subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1437 100.0 0.0 tssC VF1337 T6SS Effector delivery system VFC0086 (tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1438 100.0 5.53E-126 hcp/tssD VF1337 T6SS Effector delivery system VFC0086 (hcp/tssD) type VI secretion system tube protein Hcp [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1439 100.0 2.59E-116 tssE VF1337 T6SS Effector delivery system VFC0086 (tssE) type VI secretion system baseplate subunit TssE [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1440 99.337 0.0 tssF VF1337 T6SS Effector delivery system VFC0086 (tssF) type VI secretion system baseplate subunit TssF [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1441 99.398 0.0 tssG VF1337 T6SS Effector delivery system VFC0086 (tssG) type VI secretion system baseplate subunit TssG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1443 99.686 0.0 tssM VF1337 T6SS Effector delivery system VFC0086 (tssM) type VI secretion system membrane subunit TssM [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1447 99.664 0.0 clpV/tssH VF1337 T6SS Effector delivery system VFC0086 (clpV/tssH) type VI secretion system ATPase TssH [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1448 100.0 0.0 tssA VF1337 T6SS Effector delivery system VFC0086 (tssA) type VI secretion system protein TssA [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1449 99.559 0.0 tssK VF1337 T6SS Effector delivery system VFC0086 (tssK) type VI secretion system baseplate subunit TssK [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1450 99.627 0.0 tssL VF1337 T6SS Effector delivery system VFC0086 (tssL) type IVB secretion system protein TssL [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1452 100.0 0.0 tagX VF1337 T6SS Effector delivery system VFC0086 (tagX) type VI-associated gene X, peptidoglycan hydrolase [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1681 60.816 4.42E-101 CBU_1566 VF0696 T4SS secreted effectors Effector delivery system VFC0086 (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] Coxiella burnetii
CP001182.2_1755 100.0 3.61E-137 gspH VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspH) general secretion pathway protein H [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1756 99.206 4.39E-90 gspI VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspI) general secretion pathway protein I [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1758 99.06 0.0 gspK VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspK) general secretion pathway protein K [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_1842 99.229 0.0 lpxB VF0466 LPS Immune modulation VFC0258 (lpxB) lipid-A-disaccharide synthase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2182 61.429 2.0E-131 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
CP001182.2_2258 100.0 0.0 lpxA VF0466 LPS Immune modulation VFC0258 (lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2260 99.438 0.0 lpxD VF0466 LPS Immune modulation VFC0258 (lpxD) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2320 98.922 0.0 plc2 VF0470 Phospholipase C Exotoxin VFC0235 (plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2442 99.351 4.29E-112 pgaD VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaD) poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2443 99.759 0.0 pgaC VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2444 98.194 0.0 pgaB VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaB) poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2509 97.935 0.0 csuE VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuE) Csu pilus tip adhesin CsuE [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2510 99.159 0.0 csuD VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuD) Csu pilus usher protein CsuD [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2511 98.917 0.0 csuC VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2512 96.512 1.11E-123 csuB VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuB) Csu pilus subunit CsuB [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2514 100.0 9.77E-129 csuA/B VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuA/B) Csu pilus major pilin subunit CsuA/B [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2554 100.0 1.73E-114 gspM VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspM) general secretion pathway protein M [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2555 99.208 0.0 gspL VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspL) general secretion pathway protein L [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2587 99.145 0.0 gspE2 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2602 100.0 0.0 adeF VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeF) membrane-fusion protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2603 99.811 0.0 adeG VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2604 99.793 0.0 adeH VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2722 62.944 1.11E-87 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
CP001182.2_2747 98.201 0.0 basJ VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basJ) acinetobactin biosynthesis protein BasJ [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2748 94.422 8.47E-177 basI VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basI) phosphopantetheinyl transferase component of acinetobactin biosynthesis protein BasI [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2749 98.77 0.0 basH VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basH) non-ribosomal peptide biosynthesis thioesterase BasH [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2750 97.74 0.0 barB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barB) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2751 96.082 0.0 barA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barA) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2753 99.478 0.0 basG VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2754 99.654 0.0 basF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basF) aryl carrier protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2755 98.155 0.0 entE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (entE) non-ribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2756 95.918 0.0 basD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basD) acinetobactin biosynthesis protein BasD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2757 99.771 0.0 basC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basC) acinetobactin biosynthesis protein BasC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2758 68.725 0.0 bauA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauA) TonB-dependent siderophore receptor BauA [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2759 99.379 0.0 bauB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauB) ferric siderophore ABC transporter, periplasmic siderophore-binding protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2760 99.609 0.0 bauE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauE) ferric siderophore ABC transporter, ATP-binding protein BauE [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2761 98.095 0.0 bauC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauC) ferric siderophore ABC transporter, permease protein BauC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2762 99.333 0.0 bauD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauD) ferric siderophore ABC transporter, permease protein BauD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2765 95.858 0.0 basB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basB) non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2766 95.285 0.0 basA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basA) acinetobactin biosynthesis protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2767 98.252 0.0 bauF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauF) siderophore-interacting protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_2951 99.694 0.0 lpxM VF0466 LPS Immune modulation VFC0258 (lpxM) lysophospholipid acyltransferase family protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3008 73.004 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
CP001182.2_3233 100.0 0.0 pilJ VF1334 TFP Adherence VFC0001 (pilJ) methyl-accepting chemotaxis protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3234 98.876 1.14E-133 pilI VF1334 TFP Adherence VFC0001 (pilI) chemotaxis protein CheW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3235 100.0 1.26E-86 pilH VF1334 TFP Adherence VFC0001 (pilH) response regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3236 100.0 9.66E-94 pilG VF1334 TFP Adherence VFC0001 (pilG) twitching motility response regulator PilG [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3263 94.101 0.0 ompA VF0464 OmpA Immune modulation VFC0258 (ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3264 99.415 1.2E-126 fimT VF1334 TFP Adherence VFC0001 (fimT) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3357 99.261 0.0 plcD VF0469 Phospholipase D Exotoxin VFC0235 (plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3529 94.326 4.3E-88 pilE VF1334 TFP Adherence VFC0001 (pilE) type IV pilin protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3530 94.375 3.67E-103 ACICU_RS16840 VF1334 TFP Adherence VFC0001 (ACICU_RS16840) prepilin-type N-terminal cleavage/methylation domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3531 97.741 0.0 pilY1 VF1334 TFP Adherence VFC0001 (pilY1) VWA domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3532 99.632 0.0 pilX VF1334 TFP Adherence VFC0001 (pilX) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3533 98.799 0.0 pilW VF1334 TFP Adherence VFC0001 (pilW) PilW family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3534 100.0 3.74E-138 pilV VF1334 TFP Adherence VFC0001 (pilV) type IV pilus modification protein PilV [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3535 98.089 4.55E-109 fimU VF1334 TFP Adherence VFC0001 (fimU) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3554 99.861 0.0 pilQ VF1334 TFP Adherence VFC0001 (pilQ) type IV pilus secretin PilQ [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3555 98.286 6.07E-126 pilP VF1334 TFP Adherence VFC0001 (pilP) pilus assembly protein PilP [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3556 99.187 0.0 pilO VF1334 TFP Adherence VFC0001 (pilO) type 4a pilus biogenesis protein PilO [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3557 99.061 2.16E-160 pilN VF1334 TFP Adherence VFC0001 (pilN) PilN domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3558 99.716 0.0 pilM VF1334 TFP Adherence VFC0001 (pilM) pilus assembly protein PilM [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3686 100.0 0.0 lpxC VF0466 LPS Immune modulation VFC0258 (lpxC) UDP-3-O-acyl-N-acetylglucosamine deacetylase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
CP001182.2_3722 99.008 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii