2. PATHOGENS
Basic Information
Accession number
GCA_000170195.2
Release date
2008-07-25
Organism
Salmonella enterica subsp. enterica serovar Kentucky str. CVM29188
Species name
Salmonella enterica
Assembly level
Contig
Assembly name
ASM17019v2
Assembly submitter
TIGR
Assembly Type
haploid
Genome size
5.1 Mb
GC percent
52.0
Contig count
4
Collection date
-
Sample location
-
Host
-
Isolation source
-
Isolate type
-
Strain
CVM29188
Isolate
-
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
CP001121.1_13 # 9322 # 10467 700.0 785.793 CMY-2 100.0 ARO:3002013 protein homolog model carbapenem; cephalosporin; cephamycin; penam antibiotic inactivation CMY beta-lactamase CMY-2 is a beta-lactamase found in Klebsiella pneumoniae.
CP001122.1_3 # 2144 # 2980 500.0 568.155 APH(6)-Id 99.64 ARO:3002660 protein homolog model aminoglycoside antibiotic antibiotic inactivation APH(6) APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum.
CP001122.1_4 # 2980 # 3783 500.0 541.191 APH(3'')-Ib 99.63 ARO:3002639 protein homolog model aminoglycoside antibiotic antibiotic inactivation APH(3'') APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp.
CP001122.1_12 # 8481 # 9686 700.0 785.023 tet(B) 99.25 ARO:3000166 protein homolog model tetracycline antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline, doxycycline, and minocycline, but not tigecycline.
ABAK02000001.1_8 # 3620 # 4765 700.0 785.793 CMY-2 100.0 ARO:3002013 protein homolog model carbapenem; cephalosporin; cephamycin; penam antibiotic inactivation CMY beta-lactamase CMY-2 is a beta-lactamase found in Klebsiella pneumoniae.
ABAK02000001.1_150 # 158246 # 158923 400.0 426.402 kdpE 92.41 ARO:3003841 protein homolog model aminoglycoside antibiotic antibiotic efflux kdpDE kdpE is a transcriptional activator that is part of the two-component system KdpD/KdpE that is studied for its regulatory role in potassium transport and has been identified as an adaptive regulator involved in the virulence and intracellular survival of pathogenic bacteria. kdpE regulates a range of virulence loci through direct promoter binding.
ABAK02000001.1_299 # 318699 # 319931 700.0 726.087 Escherichia coli mdfA 87.93 ARO:3001328 protein homolog model tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Multidrug efflux pump in E. coli. This multidrug efflux system was originally identified as the Cmr/CmlA chloramphenicol exporter.
ABAK02000001.1_399 # 429917 # 431665 1000.0 1160.59 msbA 96.39 ARO:3003950 protein homolog model nitroimidazole antibiotic antibiotic efflux ATP-binding cassette (ABC) antibiotic efflux pump MsbA is a multidrug resistance transporter homolog from E. coli and belongs to a superfamily of transporters that contain an adenosine triphosphate (ATP) binding cassette (ABC) which is also called a nucleotide-binding domain (NBD). MsbA is a member of the MDR-ABC transporter group by sequence homology. MsbA transports lipid A, a major component of the bacterial outer cell membrane, and is the only bacterial ABC transporter that is essential for cell viability.
ABAK02000001.1_845 # 877399 # 877761 150.0 177.178 Klebsiella pneumoniae KpnE 76.67 ARO:3004580 protein homolog model macrolide antibiotic; aminoglycoside antibiotic; cephalosporin; tetracycline antibiotic; peptide antibiotic; rifamycin antibiotic; disinfecting agents and antiseptics antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump KpnE subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime, ceftriaxon, colistin, erythromycin, rifampin, tetracycline, and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate, deoxycholate, dyes, benzalkonium chloride, chlorhexidine, and triclosan.
ABAK02000001.1_846 # 877748 # 878077 150.0 185.267 Klebsiella pneumoniae KpnF 87.16 ARO:3004583 protein homolog model macrolide antibiotic; aminoglycoside antibiotic; cephalosporin; tetracycline antibiotic; peptide antibiotic; rifamycin antibiotic; disinfecting agents and antiseptics antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump KpnF subunit of KpnEF resembles EbrAB from E. coli. Mutation in KpnEF resulted in increased susceptibility to cefepime, ceftriaxon, colistin, erythromycin, rifampin, tetracycline, and streptomycin as well as enhanced sensitivity toward sodium dodecyl sulfate, deoxycholate, dyes, benzalkonium chloride, chlorhexidine, and triclosan.
ABAK02000001.1_883 # 914244 # 914627 230.0 251.136 marA 95.24 ARO:3000263 protein homolog model fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; glycylcycline; cephamycin; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic efflux; reduced permeability to antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump; General Bacterial Porin with reduced permeability to beta-lactams In the presence of antibiotic stress, E. coli overexpresses the global activator protein MarA, which besides inducing MDR efflux pump AcrAB, also down- regulates synthesis of the porin OmpF.
ABAK02000001.1_994 # 1032016 # 1032453 275.0 303.523 AAC(6')-Iy 99.31 ARO:3002569 protein homolog model aminoglycoside antibiotic antibiotic inactivation AAC(6') AAC(6')-Iy is a chromosomal-encoded aminoglycoside acetyltransferase in S. enteritidis and S. enterica. Regulatory mutation required to increase expression of this chromosomally-encoded gene for resistance. In the specific system, aminoglycoside resistance was due to a transcriptional fusion secondary to a chromosomal deletion in which the downstream aac(6')-Iy gene was placed under the control of the upstream nmpC promoter.
ABAK02000001.1_1368 # 1419753 # 1420475 470.0 502.286 sdiA 99.17 ARO:3000826 protein homolog model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump SdiA is a cell division regulator that is also a positive regulator of AcrAB only when it's expressed from a plasmid. When the sdiA gene is on the chromosome, it has no effect on expression of acrAB.
ABAK02000001.1_1425 # 1476105 # 1477529 900.0 930.243 MdtK 99.58 ARO:3001327 protein homolog model fluoroquinolone antibiotic antibiotic efflux multidrug and toxic compound extrusion (MATE) transporter A multidrug and toxic compound extrusions (MATE) transporter conferring resistance to norfloxacin, doxorubicin and acriflavine.
ABAK02000001.1_1498 # 1544834 # 1546000 700.0 714.531 ugd 88.92 ARO:3003577 protein homolog model peptide antibiotic antibiotic target alteration pmr phosphoethanolamine transferase PmrE is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A, which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin.
ABAK02000001.1_1549 # 1605108 # 1608230 1800.0 1874.37 mdtB 92.02 ARO:3000793 protein homolog model aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MdtB is a transporter that forms a heteromultimer complex with MdtC to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex.
ABAK02000001.1_1550 # 1608231 # 1611311 1800.0 1859.73 mdtC 91.61 ARO:3000794 protein homolog model aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MdtC is a transporter that forms a heteromultimer complex with MdtB to form a multidrug transporter. MdtBC is part of the MdtABC-TolC efflux complex. In the absence of MdtB, MdtC can form a homomultimer complex that results in a functioning efflux complex with a narrower drug specificity. mdtC corresponds to 3 loci in Pseudomonas aeruginosa PAO1 (gene name: muxC/muxB) and 3 loci in Pseudomonas aeruginosa LESB58.
ABAK02000001.1_1553 # 1614120 # 1614842 450.0 469.544 baeR 96.67 ARO:3000828 protein homolog model aminoglycoside antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump BaeR is a response regulator that promotes the expression of MdtABC and AcrD efflux complexes.
ABAK02000001.1_1722 # 1792754 # 1793899 700.0 785.793 CMY-2 100.0 ARO:3002013 protein homolog model carbapenem; cephalosporin; cephamycin; penam antibiotic inactivation CMY beta-lactamase CMY-2 is a beta-lactamase found in Klebsiella pneumoniae.
ABAK02000001.1_1725 # 1796310 # 1797293 550.0 588.186 PmrF 87.42 ARO:3003578 protein homolog model peptide antibiotic antibiotic target alteration pmr phosphoethanolamine transferase PmrF is required for the synthesis and transfer of 4-amino-4-deoxy-L-arabinose (Ara4N) to Lipid A, which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. pmrF corresponds to 1 locus in Pseudomonas aeruginosa PAO1 and 1 locus in Pseudomonas aeruginosa LESB58.
ABAK02000001.1_1728 # 1800165 # 1801811 400.0 710.679 ArnT 62.61 ARO:3005053 protein homolog model peptide antibiotic antibiotic target alteration pmr phosphoethanolamine transferase ArnT is involved in Cell Wall Biosynthesis, specifically 4-amino-4-deoxy-L-arabinose (Ara4N). It confers resistance to peptide antibiotics.
ABAK02000001.1_1902 # 1991935 # 1995048 1900.0 2018.43 acrD 94.21 ARO:3000491 protein homolog model aminoglycoside antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AcrD is an aminoglycoside efflux pump expressed in E. coli. Its expression can be induced by indole, and is regulated by baeRS and cpxAR.
ABAK02000001.1_2130 # 2265476 # 2266006 280.0 337.806 emrR 93.14 ARO:3000516 protein homolog model fluoroquinolone antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump EmrR is a negative regulator for the EmrAB-TolC multidrug efflux pump in E. coli. Mutations lead to EmrAB-TolC overexpression.
ABAK02000001.1_2131 # 2266133 # 2267305 675.0 708.368 emrA 90.0 ARO:3000027 protein homolog model fluoroquinolone antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump EmrA is a membrane fusion protein, providing an efflux pathway with EmrB and TolC between the inner and outer membranes of E. coli, a Gram-negative bacterium.
ABAK02000001.1_2132 # 2267322 # 2268860 900.0 996.882 emrB 95.7 ARO:3000074 protein homolog model fluoroquinolone antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump emrB is a translocase in the emrB -TolC efflux protein in E. coli. It recognizes substrates including carbonyl cyanide m-chlorophenylhydrazone (CCCP), nalidixic acid, and thioloactomycin.
ABAK02000001.1_2138 # 2275033 # 2275218 100.0 109.383 rsmA 85.25 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
ABAK02000001.1_2513 # 2664799 # 2665944 700.0 785.793 CMY-2 100.0 ARO:3002013 protein homolog model carbapenem; cephalosporin; cephamycin; penam antibiotic inactivation CMY beta-lactamase CMY-2 is a beta-lactamase found in Klebsiella pneumoniae.
ABAK02000001.1_2538 # 2691153 # 2691974 500.0 532.717 bacA 97.07 ARO:3002986 protein homolog model peptide antibiotic antibiotic target alteration undecaprenyl pyrophosphate related proteins The bacA gene product (BacA) recycles undecaprenyl pyrophosphate during cell wall biosynthesis which confers resistance to bacitracin.
ABAK02000001.1_2552 # 2706803 # 2707948 700.0 785.793 CMY-2 100.0 ARO:3002013 protein homolog model carbapenem; cephalosporin; cephamycin; penam antibiotic inactivation CMY beta-lactamase CMY-2 is a beta-lactamase found in Klebsiella pneumoniae.
ABAK02000001.1_2792 # 2933042 # 2933674 400.0 432.95 CRP 99.05 ARO:3000518 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; penam antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump CRP is a global regulator that represses MdtEF multidrug efflux pump expression.
ABAK02000001.1_3360 # 3582322 # 3583695 890.0 908.286 cpxA 96.94 ARO:3000830 protein homolog model aminoglycoside antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump CpxA is a membrane-localized sensor kinase that is activated by envelope stress. It starts a kinase cascade that activates CpxR, which promotes efflux complex expression.
ABAK02000001.1_3784 # 4058268 # 4059509 700.0 708.753 mdtM 86.03 ARO:3001214 protein homolog model fluoroquinolone antibiotic; lincosamide antibiotic; nucleoside antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Multidrug resistance protein MdtM.
ABAK02000001.1_3974 # 4272882 # 4273826 500.0 583.178 leuO 86.94 ARO:3003843 protein homolog model nucleoside antibiotic; disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump leuO, a LysR family transcription factor, exists in a wide variety of bacteria of the family Enterobacteriaceae and is involved in the regulation of as yet unidentified genes affecting the stress response and pathogenesis expression. LeuO is also an activator of the MdtNOP efflux pump.
ABAK02000001.1_4226 # 4557494 # 4558951 940.0 956.822 mdsC 98.35 ARO:3000791 protein homolog model monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MdsC is the outer membrane channel of the multidrug and metal efflux complex MdsABC.
ABAK02000001.1_4227 # 4558968 # 4562135 2090.0 2117.04 mdsB 99.72 ARO:3000790 protein homolog model monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MdsB is the inner membrane transporter of the multidrug and metal efflux complex MdsABC. mdsB corresponds to 1 locus in Pseudomonas aeruginosa PAO1 (gene name: mexQ) and 2 loci in Pseudomonas aeruginosa LESB58.
ABAK02000001.1_4228 # 4562132 # 4563358 770.0 808.135 mdsA 99.02 ARO:3000789 protein homolog model monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MdsA is the membrane fusion protein of the multidrug and metal efflux complex MdsABC.
ABAK02000001.1_4230 # 4565935 # 4566399 290.0 319.316 golS 100.0 ARO:3000504 protein homolog model monobactam; carbapenem; cephalosporin; cephamycin; penam; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump GolS is a regulator activated by the presence of golD, and promotes the expression of the MdsABC efflux pump.
ABAK02000001.1_4256 # 4598697 # 4599809 250.0 268.47 vanG 38.98 ARO:3002909 protein homolog model glycopeptide antibiotic antibiotic target alteration glycopeptide resistance gene cluster; Van ligase VanG is a D-Ala-D-Ala ligase homolog that can synthesize D-Ala-D-Ser, an alternative substrate for peptidoglycan synthesis that reduces vancomycin binding affinity in Enterococcus faecalis.
ABAK02000001.1_4350 # 4694347 # 4697496 1900.0 2001.87 acrB 94.57 ARO:3000216 protein homolog model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump Protein subunit of AcrA-AcrB-TolC multidrug efflux complex. AcrB functions as a herterotrimer which forms the inner membrane component and is primarily responsible for substrate recognition and energy transduction by acting as a drug/proton antiporter.
ABAK02000001.1_4351 # 4697519 # 4698712 670.0 694.886 Escherichia coli acrA 91.44 ARO:3004043 protein homolog model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AcrA is a subunit of the AcrAB-TolC multidrug efflux system found in E. coli.
ABAK02000001.1_1707 # 1776594 # 1777952 850.0 895.575 Escherichia coli GlpT with mutation conferring resistance to fosfomycin 96.9 ARO:3003889 protein variant model E448K phosphonic acid antibiotic antibiotic target alteration antibiotic-resistant GlpT Point mutations to the active importer GlpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria.
ABAK02000001.1_2771 # 2915697 # 2916881 700.0 796.579 Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin 99.49 ARO:3003369 protein variant model R234F elfamycin antibiotic antibiotic target alteration elfamycin resistant EF-Tu Sequence variants of Escherichia coli elongation factor Tu that confer resistance to Pulvomycin.
ABAK02000001.1_3103 # 3297859 # 3299250 850.0 905.975 Escherichia coli UhpT with mutation conferring resistance to fosfomycin 95.68 ARO:3003890 protein variant model E350Q phosphonic acid antibiotic antibiotic target alteration antibiotic-resistant UhpT Mutations to the active importer UhpT, which is involved with the uptake of many phosphorylated sugars, confer resistance to fosfomycin by reducing import of the drug into the bacteria.
ABAK02000001.1_3432 # 3666807 # 3667991 700.0 796.579 Escherichia coli EF-Tu mutants conferring resistance to Pulvomycin 99.49 ARO:3003369 protein variant model R234F elfamycin antibiotic antibiotic target alteration elfamycin resistant EF-Tu Sequence variants of Escherichia coli elongation factor Tu that confer resistance to Pulvomycin.
ABAK02000001.1_3981 # 4280038 # 4281804 500.0 587.8 Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics 52.9 ARO:3004446 protein variant model D350N, S357N cephalosporin; cephamycin; penam antibiotic target alteration Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics PBP3 is a penicillin-binding protein and beta-lactam resistance enzyme encoded by the ftsI gene in Haemophilus influenzae. Mutations in ftsI confer resistance to beta-lactam antibiotics.
CP001122.1_13 # 9768 # 10391 400.0 427.172 tetR 100.0 ARO:3003479 protein overexpression model tetracycline antibiotic antibiotic target alteration; antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. Mutations arise within tetR results in lower affinity for tetracyclin.
ABAK02000001.1_884 # 914647 # 915081 210.0 273.478 Escherichia coli AcrAB-TolC with MarR mutations conferring resistance to ciprofloxacin and tetracycline 92.36 ARO:3003378 protein overexpression model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic target alteration; antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MarR is a repressor of the mar operon marRAB, thus regulating the expression of marA, the activator of multidrug efflux pump AcrAB.
ABAK02000001.1_3544 # 3809512 # 3809835 200.0 212.231 Escherichia coli soxS with mutation conferring antibiotic resistance 95.33 ARO:3003511 protein overexpression model fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; glycylcycline; cephamycin; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic target alteration; antibiotic efflux; reduced permeability to antibiotic ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump; General Bacterial Porin with reduced permeability to beta-lactams SoxS is a global regulator that up-regulates the expression of AcrAB efflux genes. It also reduces OmpF expression to decrease cell membrane permeability.
ABAK02000001.1_3545 # 3809922 # 3810380 300.0 300.056 Escherichia coli soxR with mutation conferring antibiotic resistance 96.05 ARO:3003381 protein overexpression model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic target alteration; antibiotic efflux ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump SoxR is a sensory protein that upregulates soxS expression in the presence of redox-cycling drugs. This stress response leads to the expression many multidrug efflux pumps.
ABAK02000001.1_4352 # 4698854 # 4699507 375.0 394.815 Escherichia coli AcrAB-TolC with AcrR mutation conferring resistance to ciprofloxacin, tetracycline, and ceftazidime 87.38 ARO:3003807 protein overexpression model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic target alteration; antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AcrR is a repressor of the AcrAB-TolC multidrug efflux complex. AcrR mutations result in high level antibiotic resistance. The mutations associated with this model are specific to E. coli.
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
CP001122.1_83 99.591 0.0 iutA VF0565 Aerobactin Nutritional/Metabolic factor VFC0272 Aer is typically plasmid-encoded; the siderophore Aer has been distinguished as the most common siderophore secreted by hypervirulent K. pneumoniae (iutA) ferric aerobactin receptor IutA [Aerobactin (VF0565) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
CP001122.1_84 97.882 0.0 iucD VF0229 Aerobactin Nutritional/Metabolic factor VFC0272 A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae; TonB-dependent iron transport (iucD) L-lysine 6-monooxygenase IucD [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
CP001122.1_85 97.414 0.0 iucC VF0123 Aerobactin Nutritional/Metabolic factor VFC0272 A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae (iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301] Shigella flexneri
CP001122.1_86 95.873 0.0 iucB VF0229 Aerobactin Nutritional/Metabolic factor VFC0272 A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae; TonB-dependent iron transport (iucB) aerobactin siderophore biosynthesis protein IucB [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
CP001122.1_87 94.948 0.0 iucA VF0229 Aerobactin Nutritional/Metabolic factor VFC0272 A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae; TonB-dependent iron transport (iucA) aerobactin siderophore biosynthesis protein IucD [Aerobactin (VF0229) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
CP001122.1_125 99.461 0.0 iroB VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
CP001122.1_126 99.59 0.0 iroC VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroC) ATP binding cassette transporter [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
CP001122.1_127 99.267 0.0 iroD VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroD) esterase [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
CP001122.1_128 99.371 0.0 iroE VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroE) esterase [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
CP001122.1_129 99.034 0.0 iroN VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroN) salmochelin receptor IroN [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_12 87.908 0.0 gtrB VF0124 LPS Immune modulation VFC0258 Composed of the O-antigen, core polysaccharides and lipid A; the genes involved in the biosynthesis of the basic O-antigen are located in the rfb/rfc loci; O-antigen modification is associated with temperate bacteriophages. Four different serotype-converting phages have been found: SfII, Sf6, SfV and SfX, which are involved in conversion of a serotype Y stain to serotypes 2a, 3b, 5a and X, respectively (gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301] Shigella flexneri
ABAK02000001.1_13 79.167 1.61E-70 gtrA VF0124 LPS Immune modulation VFC0258 Composed of the O-antigen, core polysaccharides and lipid A; the genes involved in the biosynthesis of the basic O-antigen are located in the rfb/rfc loci; O-antigen modification is associated with temperate bacteriophages. Four different serotype-converting phages have been found: SfII, Sf6, SfV and SfX, which are involved in conversion of a serotype Y stain to serotypes 2a, 3b, 5a and X, respectively (gtrA) bactoprenol-linked glucose translocase/flippase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301] Shigella flexneri
ABAK02000001.1_39 81.854 0.0 fepA VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_40 74.121 0.0 fes VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fes) enterobactin/ferric enterobactin esterase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_42 79.212 0.0 entF VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (entF) enterobactin synthase multienzyme complex component, ATP-dependent [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_43 73.19 0.0 fepE VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fepE) LPS O-antigen length regulator [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_44 92.395 0.0 fepC VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_45 86.93 0.0 fepG VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_46 84.478 0.0 fepD VF0562 Ent Nutritional/Metabolic factor VFC0272 Various iron acquisition systems in Klebsiella are needed to overcome host defenses in different anatomical compartments. (fepD) iron-enterobactin transporter membrane protein [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_47 90.465 0.0 entS VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (entS) enterobactin exporter, iron-regulated [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_48 79.56 0.0 fepB VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_49 84.143 0.0 entC VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (entC) isochorismate synthase 1 [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_50 86.517 0.0 entE VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (entE) 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_51 88.07 0.0 entB VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (entB) isochorismatase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_52 89.516 2.19E-164 entA VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (entA) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase EntA [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_140 100.0 4.99E-111 fur VF0113 Fur Regulation VFC0301 (fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_229 92.539 0.0 slrP VF0948 TTSS effectors secreted via both systems Effector delivery system VFC0086 (slrP) type III secretion system effector SlrP (Salmonella leucine-rich repeat protein),novel E3 ubiquitin ligase [TTSS effectors secreted via both systems (VF0948) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_384 86.207 0.0 sopD2 VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (sopD2) type III secretion system effector SopD2 [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_399 66.263 0.0 msbA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_403 69.478 2.28E-125 nueA VF0473 Polar flagella Motility VFC0204 Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments (nueA) NeuA protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
ABAK02000001.1_432 92.33 0.0 ompA VF0236 OmpA Invasion VFC0083 Major outer membrane protein in E. coli, homologous to Neisseria Opa proteins which have been shown to be involved in invasion of eukaryotic cells (ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218] Escherichia coli (NMEC)
ABAK02000001.1_449 96.564 0.0 pipB VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (pipB) type III secretion system effector PipB [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_451 97.148 0.0 sopB/sigD VF0949 TTSS-1 secreted effectors Effector delivery system VFC0086 (sopB/sigD) type III secretion system effector SopB, phosphoinositide phosphatase [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_498 100.0 0.0 csgG VF0103 Agf Adherence VFC0001 Homology to csg of E.coli; nucleator-dependent assembly pathway (csgG) curli production assembly/transport protein CsgG [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_499 100.0 2.24E-100 csgF VF0103 Agf Adherence VFC0001 Homology to csg of E.coli; nucleator-dependent assembly pathway (csgF) curli production assembly/transport protein CsgF [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_500 100.0 1.59E-96 csgE VF0103 Agf Adherence VFC0001 Homology to csg of E.coli; nucleator-dependent assembly pathway (csgE) curli production assembly/transport protein CsgE [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_501 100.0 8.63E-164 csgD VF0103 Agf Adherence VFC0001 Homology to csg of E.coli; nucleator-dependent assembly pathway (csgD) DNA-binding transcriptional regulator CsgD [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_502 100.0 1.03E-108 csgB VF0103 Agf Adherence VFC0001 Homology to csg of E.coli; nucleator-dependent assembly pathway (csgB) minor curlin subunit precursor, curli nucleator protein CsgB [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_503 100.0 3.01E-106 csgA VF0103 Agf Adherence VFC0001 Homology to csg of E.coli; nucleator-dependent assembly pathway (csgA) curlin major subunit CsgA [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_504 100.0 5.6E-75 csgC VF0103 Agf Adherence VFC0001 Homology to csg of E.coli; nucleator-dependent assembly pathway (csgC) curli assembly protein CsgC [Agf (VF0103) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_533 77.372 1.37E-76 flgB VF0394 Flagella Motility VFC0204 (flgB) flagellar basal-body rod protein FlgB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_534 81.343 1.06E-80 flgC VF0394 Flagella Motility VFC0204 (flgC) flagellar basal-body rod protein FlgC [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_535 71.287 9.94E-99 flgD VF0394 Flagella Motility VFC0204 (flgD) flagellar basal-body rod modification protein FlgD [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_536 62.269 0.0 flgE VF0394 Flagella Motility VFC0204 (flgE) flagellar hook protein FlgE [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_537 69.721 8.16E-126 flgF VF0394 Flagella Motility VFC0204 (flgF) flagellar basal-body rod protein FlgF [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_538 87.308 5.49E-170 flgG VF0394 Flagella Motility VFC0204 (flgG) flagellar basal-body rod protein FlgG [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_539 82.16 4.37E-122 flgH VF0394 Flagella Motility VFC0204 (flgH) flagellar L-ring protein precursor FlgH [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_540 79.05 0.0 flgI VF0394 Flagella Motility VFC0204 (flgI) flagellar P-ring protein precursor FlgI [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_541 61.146 2.97E-137 flgJ VF0394 Flagella Motility VFC0204 (flgJ) <beta>-N-acetylglucosaminidase [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_554 77.459 1.72E-139 flmH VF0473 Polar flagella Motility VFC0204 Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments (flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
ABAK02000001.1_555 61.538 1.93E-27 acpXL VF0367 LPS Immune modulation VFC0258 Brucella possesses a non-classical LPS as compared with the so-called classical LPS from enterobacteria such as Escherichia coli. B. abortus lipid A possesses a diaminoglucose backbone (rather than glucosamine), and acyl groups are longer (C28 rather than C12 and C16) and are only linked to the core by amide bounds (rather than ester and amide bonds).; In contrast to enterobacterial LPSs, Brucella LPS is several-hundred-times less active and toxic than E. coli LPS.; this is an evolutionary adaptation to an intracellular lifestyle, low endotoxic activity is shared by other intracellular pathogens such as Bartonella and Legionella. (acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M] Brucella melitensis
ABAK02000001.1_583 91.369 0.0 sifA VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (sifA) type III secretion system effector SifA (Salmonella induced filament protein A) [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_589 100.0 0.0 phoQ VF0111 PhoPQ Regulation VFC0301 (phoQ) sensor protein PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_590 100.0 1.34E-166 phoP VF0111 PhoPQ Regulation VFC0301 (phoP) response regulator in two-component regulatory system with PhoQ [PhoPQ (VF0111) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_755 99.528 3.35E-158 ssrB VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssrB) DNA-binding response regulator [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_756 98.804 0.0 ssrA VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssrA) hybrid sensor histidine kinase/response regulator [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_757 99.213 1.66E-92 spiC/ssaB VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (spiC/ssaB) Salmonella pathogenicity island 2 protein C (SpiC); Type III secretion system apparatus protein B (SsaB) [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_758 99.598 0.0 ssaC VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaC) type III secretion system secretin SsaC [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_759 98.759 0.0 ssaD VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaD) type III secretion system outer MS ring protein SsaD [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_760 100.0 1.75E-53 ssaE VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaE) chaperone for sseB [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_761 99.065 1.98E-75 sseA VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sseA) chaperone for sseB and sseD [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_762 93.878 7.92E-137 sseB VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sseB) type III secretion system effector SseB [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_763 98.726 3.84E-116 sscA VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sscA) chaperone for sseC [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_764 92.562 0.0 sseC VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sseC) type III secretion system hydrophilic translocator, pore protein SseC [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_765 95.385 8.77E-135 sseD VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sseD) type III secretion system hydrophilic translocator, pore protein SseD [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_766 99.275 7.9E-100 sseE VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sseE) type III secretion system effector SseE [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_767 99.296 6.3E-106 sscB VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sscB) chaperone for sseF [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_768 96.154 0.0 sseF VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sseF) type III secretion system effector SseF [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_769 97.38 1.29E-168 sseG VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (sseG) type III secretion system effector SseG [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_770 100.0 1.02E-47 ssaG VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaG) type III secretion system needle filament protein SsaG [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_772 97.531 3.27E-54 ssaI VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaI) type III secretion system inner rod protein SsaI [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_773 98.795 0.0 ssaJ VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaJ) type III secretion system inner MS ring protein SsaJ [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_774 97.59 1.01E-54 ssaX VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaX) type III secretion system base-pod connector [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_775 98.214 3.15E-165 ssaK VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaK) type III secretion system stator SsaK [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_776 98.485 0.0 ssaL VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaL) type III secretion system gatekeeper SsaL [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_777 96.721 1.57E-87 ssaM VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaM) type III secretion system protein SsaM [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_778 99.413 0.0 ssaV VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaV) type III secretion system major export apparatus protein ssaV [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_779 99.538 0.0 ssaN VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaN) type III secretion system ATPase SsaN [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_780 100.0 7.09E-88 ssaO VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaO) type III secretion system stalk protein SsaO [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_781 100.0 2.45E-92 ssaP VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaP) type III secretion system needle length regulator SsaP [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_782 98.447 0.0 ssaQ VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaQ) type III secretion system C ring protein SsaQ [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_783 100.0 1.64E-153 ssaR VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaR) type III secretion system minor export apparatus protein SsaR [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_784 100.0 7.18E-59 ssaS VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaS) type III secretion system minor export apparatus protein SsaS [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_785 97.683 0.0 ssaT VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaT) type III secretion system minor export apparatus protein SsaT [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_786 99.716 0.0 ssaU VF0321 TTSS (SPI-2 encode) Effector delivery system VFC0086 SPI-2 T3SS effector repertoire varies greatly among different Salmonella serovars.; All serovars seem to have a set of 'core' effectors (SseF, SseG, PipB, SteA, SifA, SteD and PipB2), suggesting that they are critical for virulence in different hosts.; Another group of effectors (SseL, SifB, SopD2, SseJ, SteB, SteC, SlrP, and SseK2) always seem to be present in intestinal serovars but are frequently non-functional in extraintestinal or highly host-adapted serovars, suggesting these effectors contribute to virulence in the intestine, but not always in deeper tissues.;A further group of 'accessory' effectors (SspH2, SseK1, SrfJ, GtgA, GtgE, SseI, GogB, SteE, SseK3, SspH1, SpvB, SpvC, and SpvD) encoded on mobile genetic elements (MGEs) or DNA close to the remnants of MGEs are found sporadically across different serovars.;The only known effector genes in SPI-2, sseF and sseG, are likely to have conferred an early selective advantage to intracellular bacteria.;several sets of effectors that share high levels of sequence similarity. Examples of paralog effectors include Pathogenicity island-encoded protein B (PipB) and PipB2, which share 33% identity and 67% similarity, SifA and SifB that share 26% identity and 46% similarity, SopE and SopE2, which share 69% similarity, SopD and SopD2 that share 43% identity and 63% similarity. These effector protein paralogs often share structural similarity and/or biochemical activities but demonstrate functional divergence in intracellular localization and/or host protein targets or interaction partners. (ssaU) type III secretion system export apparatus switch protein SsaU [TTSS (SPI-2 encode) (VF0321) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_795 68.063 3.66E-100 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
ABAK02000001.1_959 87.619 9.66E-137 steA VF0948 TTSS effectors secreted via both systems Effector delivery system VFC0086 (steA) type III secretion system effector SteA (Salmonella translocated effector A) [TTSS effectors secreted via both systems (VF0948) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_977 93.038 0.0 sifB VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (sifB) type III secretion system effector SifB (Salmonella induced filament protein B) [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1008 98.529 0.0 sseJ VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (sseJ) type III secretion system effector SseJ, glycerophospholipid:cholesterol acyltransferase [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1076 92.56 0.0 steC VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (steC) type III secretion system effector SteC (Salmonella translocated effector C), kinase [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1131 74.653 5.92E-159 galU VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (galU) glucosephosphate uridylyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_1148 81.915 1.9E-178 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_1232 96.667 1.96E-177 sopE2 VF0949 TTSS-1 secreted effectors Effector delivery system VFC0086 (sopE2) type III secretion system effector SopE2, guanine nucleotide exchange factor [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1239 75.853 0.0 sspH2 VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (sspH2) type III secretion system effector SspH2 (Salmonella secreted protein H2), novel E3 ubiquitin ligase [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1322 60.494 6.26E-107 CBU_1566 VF0696 T4SS secreted effectors Effector delivery system VFC0086 (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] Coxiella burnetii
ABAK02000001.1_1336 85.507 0.0 flhA VF0394 Flagella Motility VFC0204 (flhA) flagellar biosynthesis protein FlhA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1337 66.053 0.0 flhB VF0394 Flagella Motility VFC0204 (flhB) flagellar biosynthetic protein FlhB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1338 78.641 5.68E-111 cheZ VF0394 Flagella Motility VFC0204 (cheZ) chemotaxis regulator CheZ [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1339 90.698 5.38E-84 cheY VF0394 Flagella Motility VFC0204 (cheY) chemotaxis regulatory protein CheY [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1340 85.387 0.0 cheB VF0394 Flagella Motility VFC0204 (cheB) chemotaxis-specific methylesterase CheB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1341 73.592 2.43E-151 cheR VF0394 Flagella Motility VFC0204 (cheR) chemotaxis methyltransferase CheR [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1343 85.0 2.26E-97 cheW VF0394 Flagella Motility VFC0204 (cheW) purine-binding chemotaxis protein CheW [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1344 75.811 0.0 cheA VF0394 Flagella Motility VFC0204 (cheA) chemotaxis protein CheA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1345 68.571 3.59E-154 motB VF0394 Flagella Motility VFC0204 (motB) flagellar motor protein MotB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1346 83.051 0.0 motA VF0394 Flagella Motility VFC0204 (motA) flagellar motor protein MotA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1347 81.865 1.31E-116 flhC VF0394 Flagella Motility VFC0204 (flhC) flagellar biosynthesis transcription activator FlhC [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1348 75.862 5.28E-53 flhD VF0394 Flagella Motility VFC0204 (flhD) flagellar transcriptional activator FlhD [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1374 83.193 9.01E-144 fliA VF0394 Flagella Motility VFC0204 (fliA) flagellar biosynthesis sigma factor [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1378 71.875 9.53E-63 fliS VF0394 Flagella Motility VFC0204 (fliS) flagellar protein FliS [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1386 63.669 0.0 fliF VF0394 Flagella Motility VFC0204 (fliF) flagellar M-ring protein FliF [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1387 83.283 0.0 fliG VF0394 Flagella Motility VFC0204 (fliG) flagellar motor switch protein G [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1389 83.921 0.0 fliI VF0394 Flagella Motility VFC0204 (fliI) flagellum-specific ATP synthase FliI [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1393 84.685 0.0 fliM VF0394 Flagella Motility VFC0204 (fliM) flagellar motor switch protein FliM [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1394 76.812 9.48E-71 fliN VF0394 Flagella Motility VFC0204 (fliN) flagellar motor switch protein FliN [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1396 85.652 1.94E-141 fliP VF0394 Flagella Motility VFC0204 (fliP) flagellar biosynthetic protein FliP [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1397 74.157 2.47E-36 fliQ VF0394 Flagella Motility VFC0204 (fliQ) flagellar biosynthetic protein FliQ [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1398 65.891 2.28E-103 fliR VF0394 Flagella Motility VFC0204 (fliR) flagellar biosynthetic protein FliR [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1399 65.217 1.71E-99 rcsA VF0571 RcsAB Regulation VFC0301 (rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1484 96.803 0.0 sopA VF0949 TTSS-1 secreted effectors Effector delivery system VFC0086 (sopA) type III secretion system effector SopA, HECT-like E3 ubiquitin ligase [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1498 81.959 0.0 ugd VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (ugd) UDP-glucose 6-dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1499 95.513 0.0 gndA VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (gndA) NADP-dependent phosphogluconate dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1512 69.944 0.0 rfbG VF0392 O-antigen Immune modulation VFC0258 Clinical Y. enterocolitica isolates from humans predominantly belong to serotypes O:3, O:9, O:8 and O:5,27; Y. enterocolitica O antigen expression is temperature regulated. (rfbG) CDP-glucose 4,6-dehydratase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1513 79.377 3.74E-162 rfbF VF0392 O-antigen Immune modulation VFC0258 Clinical Y. enterocolitica isolates from humans predominantly belong to serotypes O:3, O:9, O:8 and O:5,27; Y. enterocolitica O antigen expression is temperature regulated. (rfbF) glucose-1-phosphate cytidylyltransferase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_1516 62.759 1.38E-139 wbtL VF0542 LPS Immune modulation VFC0258 The structure of Francisella spp. lipid A is unique in that it is modified by various carbohydrates that greatly reduce TLR4 activation and allow for immune evasion (wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABAK02000001.1_1518 62.573 5.89E-159 rffG VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rffG) dTDP-glucose 46-dehydratase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_1519 92.542 0.0 galF VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (galF) GalU regulator GalF [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1524 64.24 0.0 wcaJ VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (wcaJ) undecaprenyl-phosphate glucose phosphotransferase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1525 76.484 0.0 rfbK1 VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (rfbK1) O9 family phosphomannomutase RfbK1 [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1526 61.864 0.0 KP1_RS17280 VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (KP1_RS17280) mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1527 60.688 0.0 KP1_RS17295 VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (KP1_RS17295) glycosyltransferase WbuB [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1529 76.803 0.0 KP1_RS17305 VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1530 88.378 0.0 gmd VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (gmd) GDP-mannose 4,6-dehydratase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1539 64.644 0.0 KP1_RS17340 VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (KP1_RS17340) polysaccharide export protein [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1564 73.333 3.18E-31 rhs/PAAR VF0579 T6SS Effector delivery system VFC0086 (rhs/PAAR) Type VI secretion system protein, PAAR family [T6SS (VF0579) - Effector delivery system (VFC0086)] [Shigella sonnei Ss046] Shigella sonnei
ABAK02000001.1_1575 89.189 2.15E-61 steD VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (steD) type III secretion system effector SteD [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1711 91.798 0.0 sseL VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (sseL) type III secretion system effector SseL, deubiquitinase [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_1821 72.436 3.86E-174 pla VF0139 Pla Exoenzyme VFC0251 Belongs to the family of OM proteases/adhesins known as omptins that share high sequence identity but differ in biological function; Omptins appear to constitute a unique class of proteases. Other omptin family outer membrane proteases include PgtE from S. enterica, OmpT and OmpR from E. coli, and SopA/IcsP from S. flexneri. Their catalytic residues are conserved. They require the presence of rough LPS for enzymatic activity and are inhibited by the O-antigen chains present in smooth LPS; unique to Y. pestis encoded by the pPCP1 plasmid not present in the enteropathogenic yersiniae Y. pseudotuberculosis and Y. enterocolitica (pla) plasminogen activator protease precursor [Pla (VF0139) - Exoenzyme (VFC0251)] [Yersinia pestis CO92] Yersinia pestis
ABAK02000001.1_1902 64.931 0.0 acrB VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_1953 98.904 0.0 sinH VF0400 SinH Adherence VFC0001 N-terminal 350 residues exhibits homology with invasin of Yersinia pseudotuberculosis (49.5% identity) and intimin of E. coli O111 (enteropathogenic E. coli) (48% identity). The amino termini of invasin and intimin serve as membrane-spanning anchors in the bacterial outer membrane. (sinH) intimin-like protein [SinH (VF0400) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2024 65.445 1.05E-90 algU VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABAK02000001.1_2068 98.719 0.0 bapA VF0971 BapA Adherence VFC0001 "
ABAK02000001.1_2088 87.062 0.0 iroB VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroB) glucosyltransferase IroB [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_2089 82.051 0.0 iroC VF0563 Sal Nutritional/Metabolic factor VFC0272 Salmochelin is a glycosylated Ent that requires the iroA locus for production and transport (iroC) ABC transporter [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_2090 68.101 0.0 iroD VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroD) esterase [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_2091 62.222 1.18E-133 iroE VF0230 Salmochelin siderophore Nutritional/Metabolic factor VFC0272 Also identified as virulence factors in extracellular pathogenic Escherichia coli and Salmonella enterica serotype Typhi (iroE) esterase [Salmochelin siderophore (VF0230) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABAK02000001.1_2092 84.116 0.0 iroN VF0563 Sal Nutritional/Metabolic factor VFC0272 Salmochelin is a glycosylated Ent that requires the iroA locus for production and transport (iroN) salmochelin receptor IroN [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_2094 89.714 0.0 pipB2 VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (pipB2) type III secretion system effector PipB3 [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2096 95.973 0.0 mig-14 VF0395 Mig-14 Antimicrobial activity/Competitive advantage VFC0325 Mig-14 expression is induced within macrophages and is under the control of the global regulator PhoP (mig-14) antimicrobial peptide resistance protein Mig-14 [Mig-14 (VF0395) - Antimicrobial activity/Competitive advantage (VFC0325)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2134 71.93 2.39E-93 luxS VF0406 AI-2 Biofilm VFC0271 AI-2 is produced and detected by a wide variety of bacteria and is presumed to facilitate interspecies communications. (luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
ABAK02000001.1_2138 76.667 1.4E-30 csrA VF0261 CsrA Regulation VFC0301 Belongs to a highly conserved family of global regulators that typically control stationary phase traits post-transcriptionally (csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
ABAK02000001.1_2178 99.306 0.0 avrA VF0949 TTSS-1 secreted effectors Effector delivery system VFC0086 (avrA) type III secretion system effector AvrA, acetyltransferease [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2179 98.406 0.0 sprB VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (sprB) transcriptional regulator [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2180 99.661 0.0 hilC VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (hilC) AraC family transcriptional regulator [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2181 97.333 5.6E-108 orgC VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (orgC) type III secretion system effector OrgC [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2182 100.0 1.82E-169 orgB/SctL VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (orgB/SctL) type III secretion system stator OrgB [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2183 98.438 8.15E-139 orgA/sctK VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (orgA/sctK) type III secretion system accessory cytosolic protein OrgA [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2184 100.0 0.0 prgK VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (prgK) type III secretion system inner MS ring protein PrgK [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2185 100.0 4.28E-70 prgJ VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (prgJ) type III secretion system inner rod protein PrgJ [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2186 100.0 1.28E-55 prgI VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (prgI) type III secretion system needle filament protein PrgI [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2187 99.49 0.0 prgH VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (prgH) type III secretion system outer MS ring protein PrgH [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2188 100.0 0.0 hilD VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (hilD) AraC family transcriptional regulator [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2189 100.0 0.0 hilA VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (hilA) transcriptional regulator [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2190 99.375 4.39E-119 iagB VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (iagB) invasion protein IagB [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2191 97.57 0.0 sptP VF0949 TTSS-1 secreted effectors Effector delivery system VFC0086 (sptP) type III secretion system effector SptP, tyrosine phosphatase and GTPase-activating protein [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2192 99.231 6.34E-93 sicP VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (sicP) chaparone for SptP [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2194 97.561 1.53E-54 iacP VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (iacP) putative acyl carrier protein [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2195 97.664 0.0 sipA/sspA VF0949 TTSS-1 secreted effectors Effector delivery system VFC0086 (sipA/sspA) type III secretion system effector SipA (Salmonella invasion protein A) [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2196 98.834 0.0 sipD VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (sipD) type III secretion system hydrophilic translocator, needle tip protein SipD [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2197 99.756 0.0 sipC/sspC VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (sipC/sspC) type III secretion system hydrophilic translocator, pore protein SipC [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2198 99.663 0.0 sipB/sspB VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (sipB/sspB) type III secretion system hydrophilic translocator, pore protein SipB (Salmonella invasion protein B) [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2199 100.0 1.17E-124 sicA VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (sicA) chaparone for SipC and SipB [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2200 100.0 0.0 spaS VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (spaS) type III secretion system export apparatus switch protein SpaS [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2201 100.0 0.0 spaR VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (spaR) type III secretion system minor export apparatus protein SpaR [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2202 100.0 1.03E-56 spaQ VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (spaQ) type III secretion system minor export apparatus protein SpaQ [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2203 100.0 1.06E-165 spaP VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (spaP) type III secretion system minor export apparatus protein SpaP [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2204 100.0 0.0 spaO/sctQ VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (spaO/sctQ) type III secretion system C ring protein SpaO [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2205 98.214 0.0 invJ VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invJ) type III secretion system needle length regulator InvJ [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2206 99.32 2.44E-99 invI VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invI) type III secretion system stalk protein InvI [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2207 100.0 0.0 invC/sctN VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invC/sctN) type III secretion system ATPase InvC [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2208 100.0 5.36E-99 invB VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invB) type III secretion system protein InvB [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2209 100.0 0.0 invA VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invA) type III secretion system major export apparatus protein InvA [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2210 100.0 0.0 invE VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invE) type III secretion system gatekeeper invE [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2211 99.822 0.0 invG VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invG) type III secretion system secretin invG [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2212 99.537 4.23E-163 invF VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invF) type III secretion system regulatory protein InvF [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2213 98.639 2.25E-105 invH VF0116 TTSS (SPI-1 encode) Effector delivery system VFC0086 (invH) type III secretion system pilotin invG [TTSS (SPI-1 encode) (VF0116) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2238 100.0 0.0 rpoS VF0112 RpoS Regulation VFC0301 (rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2259 99.369 0.0 sopD VF0949 TTSS-1 secreted effectors Effector delivery system VFC0086 (sopD) type III secretion system effector SopD [TTSS-1 secreted effectors (VF0949) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2454 61.212 6.88E-73 hcp/tssD VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (hcp/tssD) Hcp family type VI secretion system effector [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABAK02000001.1_2533 69.892 0.0 rfaE VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rfaE) ADP-heptose synthase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_2721 68.533 0.0 acrA VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrA) acriflavine resistance protein A [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_2722 80.845 0.0 acrB VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_2771 80.153 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABAK02000001.1_2792 67.327 4.54E-100 vfr VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (vfr) cAMP-regulatory protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABAK02000001.1_2808 63.964 1.04E-101 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABAK02000001.1_2957 98.857 1.13E-128 lpfE VF0105 Lpf Adherence VFC0001 Chaperone-usher assembly pathway (lpfE) long polar fimbrial minor subunit LpfE, adhesin [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2958 74.652 0.0 lpfD VF0105 Lpf Adherence VFC0001 Chaperone-usher assembly pathway (lpfD) long polar fimbrial protein LpfD [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2959 99.287 0.0 lpfC VF0105 Lpf Adherence VFC0001 Chaperone-usher assembly pathway (lpfC) long polar fimbrial usher protein LpfC [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2960 99.569 1.86E-172 lpfB VF0105 Lpf Adherence VFC0001 Chaperone-usher assembly pathway (lpfB) long polar fimbrial chaperone protein LpfB [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_2961 97.701 1.66E-120 lpfA VF0105 Lpf Adherence VFC0001 Chaperone-usher assembly pathway (lpfA) long polar fimbria protein LpfA [Lpf (VF0105) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3027 77.922 0.0 rfaD VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rfaD) ADP-L-glycero-D-mannoheptose-6-epimerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_3028 63.714 1.96E-157 rfaF VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rfaF) ADP-heptose-LPS heptosyltransferase II [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_3070 98.01 0.0 misL VF0397 MisL Adherence VFC0001 MisL is located within Salmonella Pathogenicity Island SPI-3 (misL) putative autotransporter [MisL (VF0397) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3076 99.78 0.0 mgtB VF0106 MgtB Nutritional/Metabolic factor VFC0272 A magnesium transporter (mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3078 99.119 1.42E-166 mgtC VF1365 MgtC Nutritional/Metabolic factor VFC0272 An inner membrane protein; anti-virulence protein CigR inhibits the virulence functions of MgtC at early times inside macrophages (mgtC) Salmonella virulence protein MgtC [MgtC (VF1365) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3226 65.179 1.46E-169 rffG VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rffG) dTDP-glucose 46-dehydratase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_3415 89.081 0.0 ibeC VF0237 Ibes Invasion VFC0083 IbeA is unique to E. coli K1. The ibeB and ibeC are found to have K12 homologues p77211 and yijP respectively. (ibeC) phosphoethanolamine transferase CptA [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88] Escherichia coli (NMEC)
ABAK02000001.1_3432 80.153 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABAK02000001.1_3444 99.107 0.0 sseK1 VF0947 TTSS-2 secreted effectors Effector delivery system VFC0086 (sseK1) type III secretion system effector SseK1, Arginine N-Glycosyltransferase [TTSS-2 secreted effectors (VF0947) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3466 61.827 0.0 icl VF0253 Isocitrate lyase Others VFC0346 (icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv] Mycobacterium tuberculosis
ABAK02000001.1_3485 84.437 0.0 gtrB VF0124 LPS Immune modulation VFC0258 Composed of the O-antigen, core polysaccharides and lipid A; the genes involved in the biosynthesis of the basic O-antigen are located in the rfb/rfc loci; O-antigen modification is associated with temperate bacteriophages. Four different serotype-converting phages have been found: SfII, Sf6, SfV and SfX, which are involved in conversion of a serotype Y stain to serotypes 2a, 3b, 5a and X, respectively (gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301] Shigella flexneri
ABAK02000001.1_3540 94.695 0.0 siiE VF0970 SiiE Adherence VFC0001 SiiE is located within Salmonella Pathogenicity Island SPI-4, a 27-kb region that carries six genes designated siiABCDEF. SiiC, SiiD, and SiiF form a type I secretion apparatus for the secretion of SiiE.;With 595 kDa, SiiE is the largest protein of the Salmonella proteome.;SiiE, like many other non-fimbrial adhesins binds to glycostructures at the cell surface. (siiE) non-fimbrial adhesin SiiE [SiiE (VF0970) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3572 99.719 0.0 pmrB VF1355 PmrAB Regulation VFC0301 (pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3573 100.0 4.18E-165 pmrA VF1355 PmrAB Regulation VFC0301 (pmrA) response regulator PmrA [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_3619 75.758 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
ABAK02000001.1_3799 72.352 0.0 cheD VF0394 Flagella Motility VFC0204 (cheD) methyl-accepting chemotaxis protein CheD [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
ABAK02000001.1_3993 77.303 0.0 lpxC VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lpxC) UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_4100 64.201 5.76E-159 lpxD VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lpxD) UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_4102 67.939 4.76E-131 lpxA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lpxA) UDP-N-acetylglucosamine acyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_4103 64.987 5.01E-180 lpxB VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lpxB) lipid-A-disaccharide synthase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_4119 67.897 1.25E-127 IlpA VF0513 IlpA Adherence VFC0001 (IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016] Vibrio vulnificus
ABAK02000001.1_4134 99.43 0.0 STM0266 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4135 99.396 0.0 STM0267 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4136 99.841 0.0 STM0268 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4137 100.0 1.42E-121 STM0269 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4138 98.54 0.0 STM0270 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4139 98.667 0.0 STM0271 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4140 99.09 0.0 STM0272 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4141 99.444 6.21E-130 STM0273 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4142 99.801 0.0 STM0274 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4144 100.0 2.36E-121 STM0276 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4145 100.0 2.56E-120 tae4 VF1195 SCI T6SS secreted effectors Effector delivery system VFC0086 (tae4) type VI secretion system effector tae4, L,D-endopeptidase [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4146 98.374 3.56E-89 STM0278 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4147 100.0 1.32E-120 STM0279 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4148 97.191 2.3E-128 tssJ VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4149 100.0 0.0 tssK VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4150 99.77 0.0 STM0282 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4151 97.656 0.0 STM0283 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4152 99.301 3.7E-102 STM0284 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4153 99.69 0.0 STM0285 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4154 98.431 0.0 STM0286 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4159 80.137 0.0 vgrG VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4165 98.438 7.95E-95 STM0287 VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4166 100.0 5.13E-130 tlde1 VF1195 SCI T6SS secreted effectors Effector delivery system VFC0086 (tlde1) type VI secretion system effector tlde1, L,D-transpeptidase [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4167 86.853 0.0 vgrG VF0974 SCI (Salmonella centrisome island)/SPI-6 T6SS Effector delivery system VFC0086 "The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1,
ABAK02000001.1_4184 99.163 1.46E-176 pagN VF0968 PagN Invasion VFC0083 Unlike rck, pagN is encoded on bacterial chromosome.;PagN is well conserved and widely distributed among the different species and subspecies of Salmonella.;PagN protein displays similarity to the Hek and Tia invasins/adhesins of pathogenic E. coli (pagN) outer membrane adhesin/invasin protein [PagN (VF0968) - Invasion (VFC0083)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4188 76.042 9.67E-111 gmhA/lpcA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (gmhA/lpcA) phosphoheptose isomerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABAK02000001.1_4227 60.478 0.0 adeG VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
ABAK02000001.1_4324 66.495 2.42E-98 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
ABAK02000001.1_4350 92.088 0.0 acrB VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4351 85.025 0.0 acrA VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrA) acriflavine resistance protein A [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4390 73.77 4.84E-172 allS VF0572 Allantion utilization Nutritional/Metabolic factor VFC0272 An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. (allS) DNA-binding transcriptional activator AllS [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4391 78.75 1.05E-94 allA VF0572 Allantion utilization Nutritional/Metabolic factor VFC0272 An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. (allA) ureidoglycolate hydrolase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4392 85.874 9.99E-177 allR VF0572 Allantion utilization Nutritional/Metabolic factor VFC0272 An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. (allR) DNA-binding transcriptional repressor AllR [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4398 93.377 0.0 allB VF0572 Allantion utilization Nutritional/Metabolic factor VFC0272 An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. (allB) allantoinase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4402 80.44 0.0 allC VF0572 Allantion utilization Nutritional/Metabolic factor VFC0272 An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. (allC) allantoate amidohydrolase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4403 81.948 0.0 allD VF0572 Allantion utilization Nutritional/Metabolic factor VFC0272 An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. (allD) ureidoglycolate dehydrogenase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABAK02000001.1_4418 97.297 2.31E-130 fimA VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimA) type-1 fimbrial protein subunit A [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4419 98.305 5.28E-130 fimI VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimI) fimbrial protein internal segment [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4420 98.261 3.74E-168 fimC VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimC) chaperone protein FimC [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4421 99.195 0.0 fimD VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimD) usher protein FimD [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4422 98.507 0.0 fimH VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimH) type I fimbriae minor fimbrial subunit FimH, adhesin [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4423 98.256 2.74E-124 fimF VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimF) type I fimbriae adaptor protein FimF [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4424 99.524 1.09E-154 fimZ VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimZ) DNA-binding response regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4425 99.167 6.84E-178 fimY VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimY) fimbriae Y protein [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABAK02000001.1_4427 98.485 4.85E-148 fimW VF0102 Type 1 fimbriae Adherence VFC0001 Chaperone-usher assembly pathway (fimW) helix-turn-helix transcriptional regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)