2. PATHOGENS
Basic Information
Accession number
GCA_000172395.1
Release date
2009-09-15
Organism
Pseudomonas aeruginosa PAb1
Species name
Pseudomonas aeruginosa
Assembly level
Contig
Assembly name
ASM17239v1
Assembly submitter
The University of Maryland Center For Bioinformatics & Computational Biology
Assembly Type
haploid
Genome size
6.1 Mb
GC percent
67.0
Contig count
658
Collection date
-
Sample location
-
Host
Homo sapiens
Isolation source
clininal isolate from frostbite patient
Isolate type
-
Strain
PAb1
Isolate
-
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
ABKZ01000650.1_9 # 9408 # 10196 500.0 535.413 OXA-848 99.62 ARO:3006041 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-848 is a OXA beta-lactamase.
ABKZ01000610.1_10 # 10770 # 11102 170.0 206.838 Pseudomonas aeruginosa emrE 100.0 ARO:3004038 protein homolog model aminoglycoside antibiotic antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump EmrE is a small multidrug transporter that functions as a homodimer and that couples the efflux of small polyaromatic cations from the cell with the import of protons down an electrochemical gradient. Confers resistance to tetraphenylphosphonium, methyl viologen, gentamicin, kanamycin, and neomycin.
ABKZ01000593.1_3 # 1474 # 2907 900.0 940.258 basS 99.16 ARO:3003583 protein homolog model peptide antibiotic antibiotic target alteration; antibiotic efflux pmr phosphoethanolamine transferase Histidine protein kinase sensor Lipid A modification gene; part of a two-component system involved in polymyxin resistance that senses high extracellular Fe(2+).
ABKZ01000575.1_10 # 10712 # 12151 850.0 933.71 OprJ 99.37 ARO:3000802 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OprJ is the outer membrane channel component of the MexCD-OprJ multidrug efflux complex.
ABKZ01000575.1_11 # 12157 # 15288 1800.0 1922.52 MexD 94.76 ARO:3000801 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexD is the multidrug inner membrane transporter of the MexCD-OprJ complex.
ABKZ01000575.1_12 # 15316 # 16380 600.0 680.633 MexC 98.87 ARO:3000800 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexC is the membrane fusion protein of the MexCD-OprJ multidrug efflux complex.
ABKZ01000484.1_18 # 17410 # 18540 650.0 744.191 MexV 99.47 ARO:3003030 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexV is the membrane fusion protein of the MexVW-OprM multidrug efflux complex.
ABKZ01000484.1_19 # 18591 # 21647 1900.0 2045.4 MexW 99.8 ARO:3003031 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexW is the RND-type membrane protein of the efflux complex MexVW-OprM.
ABKZ01000466.1_6 # 3094 # 3732 400.0 437.958 Pseudomonas aeruginosa catB7 98.58 ARO:3002679 protein homolog model phenicol antibiotic antibiotic inactivation chloramphenicol acetyltransferase (CAT) catB7 is a chromosome-encoded variant of the cat gene found in Pseudomonas aeruginosa.
ABKZ01000460.1_33 # 31288 # 32109 50.0 149.443 vanW gene in vanG cluster 32.58 ARO:3002965 protein homolog model glycopeptide antibiotic antibiotic target alteration vanW; glycopeptide resistance gene cluster Also known as vanWG, is a vanW variant found in the vanG gene cluster.
ABKZ01000451.1_13 # 10745 # 10930 100.0 122.865 rsmA 100.0 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
ABKZ01000449.1_4 # 4051 # 5040 200.0 200.29 vanH gene in vanB cluster 40.91 ARO:3002943 protein homolog model glycopeptide antibiotic antibiotic target alteration vanH; glycopeptide resistance gene cluster Also known as vanHB, is a vanH variant in the vanB gene cluster.
ABKZ01000430.1_2 # 538 # 945 200.0 273.478 FosA 100.0 ARO:3000149 protein homolog model phosphonic acid antibiotic antibiotic inactivation fosfomycin thiol transferase An enzyme that confers resistance to fosfomycin in Serratia marcescens by breaking the epoxide ring of the molecule. It depends on the cofactors Manganese (II) and Potassium and uses Glutathione (GSH) as the nucleophilic molecule. In Pseudomonas aeruginosa, FosA catalyzes the conjugation of glutathione to carbon-1 of fosfomycin, rendering it ineffective as an antibacterial drug.
ABKZ01000412.1_5 # 4925 # 6358 900.0 941.028 PmpM 99.79 ARO:3004077 protein homolog model fluoroquinolone antibiotic; aminoglycoside antibiotic; disinfecting agents and antiseptics antibiotic efflux multidrug and toxic compound extrusion (MATE) transporter PmpM is a multidrug efflux pump belonging to the MATE family of Pseudomonas aeruginosa. PmpM is an H+ drug antiporter and is the first reported case of an H+ coupled efflux pump in the MATE family. PmpM confers resistance to fluoroquinolones, fradiomycin, benzalkonium chloride, chlorhexidine gluconate, ethidium bromide, tetraphenylphosphonium chloride (TPPCl), and rhodamine 6G.
ABKZ01000401.1_49 # 42456 # 45566 1900.0 2059.26 mexN 99.71 ARO:3003705 protein homolog model phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexN is the inner membrane transporter of the MexMN-OprM multidrug efflux complex.
ABKZ01000401.1_50 # 45563 # 46720 650.0 737.643 mexM 98.96 ARO:3003704 protein homolog model phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump mexM is the membrane fusion protein of the MexMN-OprM multidrug efflux complex.
ABKZ01000381.1_7 # 8724 # 9431 400.0 469.159 ParR 99.15 ARO:3005068 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic efflux; reduced permeability to antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump; Outer Membrane Porin (Opr) ParR is a component of the two-component sensor ParRS. Alongside its counterpart ParS, it confers resistance to polycationic antibiotics through the regulation of efflux components and porins.
ABKZ01000381.1_8 # 9432 # 10718 800.0 857.055 ParS 99.53 ARO:3005067 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic efflux; reduced permeability to antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump; Outer Membrane Porin (Opr) ParS is the sensor component of the two-component ParRS system. Alongside its counterpart ParR, it confers resistance to polycationic antibiotics though regulation of efflux pumps and porins.
ABKZ01000353.1_6 # 4715 # 7852 1800.0 1912.5 mexY 93.21 ARO:3003033 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexY is the RND-type membrane protein of the efflux complex MexXY-OprM.
ABKZ01000318.1_7 # 4890 # 5360 200.0 314.694 Pseudomonas aeruginosa soxR 100.0 ARO:3004107 protein homolog model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic target alteration; antibiotic efflux ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump SoxR is a redox-sensitive transcriptional activator that induces expression of a small regulon that includes the RND efflux pump-encoding operon mexGHI-opmD. SoxR was shown to be activated by pyocyanin.
ABKZ01000277.1_9 # 6396 # 7814 800.0 916.761 OprN 99.58 ARO:3000805 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OprN is the outer membrane channel component of the MexEF-OprN multidrug efflux complex.
ABKZ01000277.1_10 # 7811 # 10999 2110.0 2147.09 MexF 100.0 ARO:3000804 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB).
ABKZ01000277.1_11 # 11021 # 12265 750.0 833.558 MexE 99.76 ARO:3000803 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexE is the membrane fusion protein of the MexEF-OprN multidrug efflux complex.
ABKZ01000275.1_12 # 11549 # 12829 800.0 846.269 MuxA 99.77 ARO:3004073 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MuxA is a membrane fusion protein component of the efflux pump system MuxABC-OpmB in Pseudomonas aeruginosa.
ABKZ01000275.1_13 # 12826 # 15957 1900.0 2071.2 MuxB 99.81 ARO:3004074 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MuxB is one of the two necessary RND components in the Pseudomonas aeruginosa efflux pump system MuxABC-OpmB.
ABKZ01000275.1_14 # 15954 # 19064 1900.0 2078.91 MuxC 100.0 ARO:3004075 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MuxC is one of the two necessary RND components of the MuxABC-OpmB efflux pumps system in Pseudomonas aeruginosa.
ABKZ01000275.1_15 # 19061 # 20557 850.0 1004.2 OpmB 100.0 ARO:3004072 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OpmB is an outer membrane efflux protein in Pseudomonas aeruginosa that shows functional cooperation with MuxABC, to form the efflux pump system MuxABC-OpmB.
ABKZ01000187.1_13 # 15460 # 16755 800.0 869.766 cprS 99.77 ARO:3005064 protein homolog model peptide antibiotic antibiotic target alteration; antibiotic efflux pmr phosphoethanolamine transferase cprS is part of a two-component regulatory system that, with its counterpart cprR, induces the Arn operon in the presence of cationic peptides to confer resistance.
ABKZ01000187.1_14 # 16752 # 17423 400.0 453.366 cprR 100.0 ARO:3005063 protein homolog model peptide antibiotic antibiotic target alteration; antibiotic efflux pmr phosphoethanolamine transferase cprR is one part of a two-component regulatory system. It with its counterpart cprS induce the Arn operon to confer resistance to peptide antibiotics.
ABKZ01000177.1_14 # 10680 # 11357 400.0 441.039 Pseudomonas aeruginosa CpxR 100.0 ARO:3004054 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump CpxR is directly involved in activation of expression of RND efflux pump MexAB-OprM in P. aeruginosa. CpxR is required to enhance mexAB-oprM expression and drug resistance, in the absence of repressor MexR.
ABKZ01000149.1_19 # 19821 # 21470 400.0 443.351 ArnT 43.75 ARO:3005053 protein homolog model peptide antibiotic antibiotic target alteration pmr phosphoethanolamine transferase ArnT is involved in Cell Wall Biosynthesis, specifically 4-amino-4-deoxy-L-arabinose (Ara4N). It confers resistance to peptide antibiotics.
ABKZ01000149.1_21 # 22351 # 24339 1200.0 1345.49 arnA 99.55 ARO:3002985 protein homolog model peptide antibiotic antibiotic target alteration pmr phosphoethanolamine transferase arnA modifies lipid A with 4-amino-4-deoxy-L-arabinose (Ara4N) which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. arnA is found in E. coli and P. aeruginosa.
ABKZ01000149.1_52 # 62560 # 63717 650.0 753.821 mexP 99.48 ARO:3003698 protein homolog model macrolide antibiotic; carbapenem; tetracycline antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexP is the membrane fusion protein of the MexPQ-OpmE multidrug efflux complex.
ABKZ01000149.1_53 # 63714 # 66875 1900.0 2081.99 mexQ 99.72 ARO:3003699 protein homolog model macrolide antibiotic; carbapenem; tetracycline antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexQ is the inner membrane transporter of the multidrug efflux pump MexPQ-OpmE.
ABKZ01000149.1_54 # 66872 # 68347 850.0 947.577 opmE 99.39 ARO:3003700 protein homolog model macrolide antibiotic; carbapenem; tetracycline antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump opmE is an outer membrane factor protein that is part of the multidrug efflux pump MexPQ-OpmE.
ABKZ01000141.1_13 # 12710 # 13348 400.0 426.402 MexL 99.53 ARO:3003710 protein homolog model macrolide antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexL is a specific repressor of mexJK transcription and autoregulates its own expression.
ABKZ01000141.1_14 # 13444 # 14547 690.0 721.079 MexJ 99.18 ARO:3003692 protein homolog model macrolide antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexJ is the membrane fusion protein of the MexJK multidrug efflux protein.
ABKZ01000141.1_15 # 14552 # 17629 1900.0 2061.57 MexK 99.9 ARO:3003693 protein homolog model macrolide antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexK is the inner membrane resistance-nodulation-cell division (RND) transporter in the MexJK multidrug efflux protein.
ABKZ01000134.1_3 # 2489 # 2827 200.0 223.787 YajC 100.0 ARO:3005040 protein homolog model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; oxazolidinone antibiotic; glycopeptide antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump YajC interacts with the AcrAB-TolC efflux pump in a way that in uncharacterized but is shown to grant increased fitness in the presence of linezolid, rifampicin, and vancomycin.
ABKZ01000101.1_3 # 4991 # 6184 700.0 806.209 PDC-30 100.0 ARO:3006670 protein homolog model monobactam; carbapenem; cephalosporin antibiotic inactivation PDC beta-lactamase PDC-30 is a PDC beta-lactamase.
ABKZ01000095.1_1 # 203 # 1411 500.0 754.592 bcr-1 99.75 ARO:3003801 protein homolog model bicyclomycin-like antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Transmembrane protein which expels bicyclomycin from the cell, leading to bicyclomycin resistance. Identified in Pseudomonas aeruginosa strains responsible for outbreaks in Brazil, often appearing with blaSPM-1, another bicyclomycin resistance gene.
ABKZ01000089.1_4 # 2571 # 4034 920.0 948.347 OpmD 99.59 ARO:3000809 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OpmD is the outer membrane channel protein of the efflux complex MexGHI-OpmD.
ABKZ01000089.1_5 # 4031 # 7120 1900.0 2057.72 MexI 99.9 ARO:3000808 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexI is the inner membrane transporter of the efflux complex MexGHI-OpmD.
ABKZ01000089.1_6 # 7133 # 8245 650.0 730.709 MexH 100.0 ARO:3000807 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexH is the membrane fusion protein of the efflux complex MexGHI-OpmD.
ABKZ01000089.1_7 # 8253 # 8699 260.0 291.197 MexG 100.0 ARO:3000806 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexG is a membrane protein required for MexGHI-OpmD efflux activity.
ABKZ01000047.1_1 # 3 # 1475 850.0 963.37 OprM 100.0 ARO:3000379 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OprM is an outer membrane factor protein found in Pseudomonas aeruginosa and Burkholderia vietnamiensis. It is part of the MexAB-OprM, MexVW-OprM, MexXY-OprM and the AmrAB-OprM complex.
ABKZ01000046.1_99 # 99293 # 100444 650.0 768.074 MexA 100.0 ARO:3000377 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexA is the membrane fusion protein of the MexAB-OprM multidrug efflux complex.
ABKZ01000046.1_100 # 100460 # 103573 1950.0 2102.79 MexB 99.9 ARO:3000378 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexB is the inner membrane multidrug exporter of the efflux complex MexAB-OprM.
ABKZ01000026.1_16 # 15389 # 16492 650.0 719.153 TriA 98.64 ARO:3003679 protein homolog model disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump TriA is a membrane protein that is fused to TriB and both are required for the triclosan efflux pump function of TriABC-OpmH in P. aeruginosa.
ABKZ01000026.1_17 # 16489 # 17559 600.0 698.353 TriB 99.72 ARO:3003680 protein homolog model disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump TriB is a membrane protein that is fused to TriA and both are required for the triclosan efflux pump function of TriABC-OpmH in P. aeruginosa.
ABKZ01000026.1_18 # 17556 # 20603 1900.0 2050.79 TriC 99.9 ARO:3003681 protein homolog model disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump TriC is a resistance nodulation cell division (RND) transporter that is a part of TriABC-OpmH, a triclosan-specific efflux protein.
ABKZ01000575.1_13 # 16640 # 17203 310.0 384.03 Type B NfxB 100.0 ARO:3004060 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump Type B NfxB mutants are more resistant to tetracycline and chloramphenicol, as well as ofloxacin, erythromycin, and the new zwitterionic cephems, than was PAO1, and they are four to eight times more susceptible to carbenicillin, sulbenicillin, imipenem, panipenem, biapenem, moxalactam, aztreonam, gentamicin, and kanamycin than PAO1. The mutation at the 46th amino acid position is sufficient for overproduction of OprJ and the multidrug resistance. nfxB corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: esrC/nfxB) and 2 loci in Pseudomonas aeruginosa LESB58 (gene name: nfxB).
ABKZ01000353.1_4 # 2712 # 3344 390.0 423.705 MexZ 100.0 ARO:3003709 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexZ is a transcriptional regulator that downregulates the mexXY multidrug transporter operon, which confers to aminoglycoside resistance on Pseudomonas aeruginosa.
ABKZ01000277.1_12 # 12496 # 13410 500.0 534.258 MexT 99.63 ARO:3000814 protein overexpression model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexT is a LysR-type transcriptional activator that positively regulates the expression of MexEF-OprN, OprD, and MexS.
ABKZ01000277.1_13 # 13631 # 14650 660.0 689.493 MexS 100.0 ARO:3000813 protein overexpression model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexS is a suppressor of MexT, which is an activator of the multidrug pump MexEF-OprN. Mutations in MexS lead to multidrug resistance.
ABKZ01000148.1_5 # 1530 # 2168 375.0 436.032 nalD 100.0 ARO:3000819 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump NalD is a repressor of MexAB-OprM. Mutations lead to multidrug resistance and MexAB-OprM overexpression.
ABKZ01000139.1_13 # 17832 # 18473 400.0 427.557 nalC 99.06 ARO:3000818 protein overexpression model S209R, G71E macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump NalC is a repressor of PA3720-PA3719, which are positive regulators of MexAB-OprM. Thus, nalC mutants confer multidrug resistance.
ABKZ01000046.1_98 # 98575 # 99018 270.0 297.745 MexR 100.0 ARO:3000506 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic target alteration; antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexR is the repressor of the MexRAB-OprM operon. Mutant forms of mexR result in up-regulation of efflux pump system MexAB-OprM.
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
ABKZ01000647.1_9 99.332 0.0 algB VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algB) two-component response regulator AlgB [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000639.1_9 100.0 0.0 crc VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (crc) catabolite repression control protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000638.1_13 99.078 0.0 algC VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algC) phosphomannomutase AlgC [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000636.1_2 100.0 1.69E-130 hcpA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (hcpA) Hcp family type VI secretion system effector [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000635.1_56 97.727 0.0 algP/algR3 VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algP/algR3) alginate regulatory protein AlgP [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000635.1_58 100.0 1.13E-117 algQ VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algQ) Alginate regulatory protein AlgQ [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000635.1_64 100.0 0.0 algR VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algR) alginate biosynthesis regulatory protein AlgR [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000635.1_65 100.0 0.0 algZ VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algZ) sigma factor AlgU [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000633.1_3 61.856 8.41E-132 wbtL VF0542 LPS Immune modulation VFC0258 The structure of Francisella spp. lipid A is unique in that it is modified by various carbohydrates that greatly reduce TLR4 activation and allow for immune evasion (wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABKZ01000626.1_1 99.277 0.0 pldB/tle5b VF1350 HSI-3 T6SS secreted effectors Effector delivery system VFC0086 (pldB/tle5b) phospholipase D [HSI-3 T6SS secreted effectors (VF1350) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000617.1_1 100.0 1.55E-14 pilN VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilN) type IV pilus inner membrane platform protein PilN [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000617.1_2 100.0 0.0 pilM VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilM) type IV pilus inner membrane platform protein PilM [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000616.1_1 100.0 3.17E-95 pilN VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilN) type IV pilus inner membrane platform protein PilN [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000615.1_1 99.749 0.0 pilQ VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilQ) type 4 fimbrial biogenesis protein PilQ [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000615.1_2 100.0 2.97E-33 pilP VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilP) type IV pilus biogenesis protein PilP [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000614.1_18 92.593 8.9E-12 pilQ VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilQ) type 4 fimbrial biogenesis protein PilQ [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000611.1_4 99.627 0.0 waaP VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaP) UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase WaaG [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000611.1_5 98.928 0.0 waaG VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaG) B-band O-antigen polymerase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000611.1_6 100.0 0.0 waaC VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaC) 3-deoxy-D-manno-octulosonic-acid (KDO) transferase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000611.1_7 100.0 0.0 waaF VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaF) heptosyltransferase I [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000610.1_8 99.529 0.0 waaA VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaA) lipopolysaccharide core biosynthesis protein WaaP [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000607.1_27 99.712 0.0 motB VF0273 Flagella Motility VFC0204 (motB) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000607.1_28 98.94 0.0 motA VF0273 Flagella Motility VFC0204 (motA) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000607.1_33 100.0 0.0 fimX VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimX) protein FimX [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000601.1_13 67.347 4.7E-102 ureG VF0050 Urease Stress survival VFC0282 (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
ABKZ01000598.1_1 61.728 0.0 ureB VF0050 Urease Stress survival VFC0282 (ureB) urease beta subunit UreB, urea amidohydrolase [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
ABKZ01000595.1_17 71.023 0.0 mgtB VF0106 MgtB Nutritional/Metabolic factor VFC0272 A magnesium transporter (mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
ABKZ01000573.1_6 99.811 0.0 pilS VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilS) two-component sensor PilS [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000573.1_7 99.775 0.0 pilR VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilR) two-component response regulator PilR [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000501.1_1 98.958 0.0 xcpA/pilD VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (xcpA/pilD) type 4 prepilin peptidase PilD [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000500.1_1 100.0 2.01E-40 pilB VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilB) type 4 fimbrial biogenesis protein PilB [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000499.1_1 98.425 8.92E-88 pilB VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilB) type 4 fimbrial biogenesis protein PilB [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000498.1_1 100.0 2.34E-75 pilB VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilB) type 4 fimbrial biogenesis protein PilB [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000496.1_4 60.971 0.0 ibeC VF0237 Ibes Invasion VFC0083 IbeA is unique to E. coli K1. The ibeB and ibeC are found to have K12 homologues p77211 and yijP respectively. (ibeC) phosphoethanolamine transferase CptA [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88] Escherichia coli (NMEC)
ABKZ01000487.1_3 99.229 0.0 algW VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algW) AlgW protein [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000487.1_20 100.0 0.0 rpoN VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (rpoN) RNA polymerase factor sigma-54 [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000484.1_10 66.492 3.06E-99 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
ABKZ01000484.1_30 76.908 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
ABKZ01000460.1_15 99.578 0.0 mucD VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucD) serine protease MucD precursor [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000460.1_16 100.0 1.12E-104 mucC VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucC) negative regulator for alginate biosynthesis MucB [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000460.1_17 99.684 0.0 mucB VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucB) anti-sigma factor MucA, inhibitor of alg gene expression [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000460.1_18 100.0 3.9E-141 mucA VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucA) alkaline metalloproteinase precursor [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000460.1_19 100.0 4.9E-143 algU VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000453.1_5 99.452 0.0 plcH VF0092 PLC Exotoxin VFC0235 (plcH) hemolytic phospholipase C precursor [PLC (VF0092) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000451.1_13 73.333 4.53E-30 csrA VF0261 CsrA Regulation VFC0301 Belongs to a highly conserved family of global regulators that typically control stationary phase traits post-transcriptionally (csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
ABKZ01000448.1_8 60.402 0.0 iroN VF0563 Sal Nutritional/Metabolic factor VFC0272 Salmochelin is a glycosylated Ent that requires the iroA locus for production and transport (iroN) salmochelin receptor IroN [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABKZ01000444.1_13 63.525 7.28E-113 CBU_1566 VF0696 T4SS secreted effectors Effector delivery system VFC0086 (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] Coxiella burnetii
ABKZ01000441.1_3 100.0 0.0 exoU VF0853 TTSS secreted effectors Effector delivery system VFC0086 (exoU) type III secretion system effector ExoU, phospholipase A2 activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa UCBPP-PA14] Pseudomonas aeruginosa
ABKZ01000432.1_5 99.772 0.0 flgL VF0273 Flagella Motility VFC0204 (flgL) flagellar hook-associated protein 3 FlgL [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_6 99.414 0.0 flgK VF0273 Flagella Motility VFC0204 (flgK) flagellar hook-associated protein 1 FlgK [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_7 99.5 0.0 flgJ VF0273 Flagella Motility VFC0204 (flgJ) flagellar rod assembly protein/muramidase FlgJ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_8 100.0 0.0 flgI VF0273 Flagella Motility VFC0204 (flgI) flagellar P-ring protein precursor FlgI [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_9 100.0 7.18E-172 flgH VF0273 Flagella Motility VFC0204 (flgH) flagellar L-ring protein precursor FlgH [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_10 100.0 0.0 flgG VF0273 Flagella Motility VFC0204 (flgG) flagellar basal-body rod protein FlgG [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_11 100.0 0.0 flgF VF0273 Flagella Motility VFC0204 (flgF) flagellar basal-body rod protein FlgF [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_12 99.784 0.0 flgE VF0273 Flagella Motility VFC0204 (flgE) flagellar hook protein FlgE [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_13 99.578 1.97E-171 flgD VF0273 Flagella Motility VFC0204 (flgD) flagellar basal-body rod modification protein FlgD [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_14 100.0 3.05E-107 flgC VF0273 Flagella Motility VFC0204 (flgC) flagellar basal-body rod protein FlgC [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000432.1_15 100.0 7.62E-99 flgB VF0273 Flagella Motility VFC0204 (flgB) flagellar basal body rod protein FlgB [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_1 99.441 8.45E-124 rhlC VF0089 Rhamnolipid Immune modulation VFC0258 Nonenzyme glycolipid (rhlC) rhamnosyltransferase 2 [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_28 99.32 1.1E-102 fliJ VF0273 Flagella Motility VFC0204 (fliJ) flagellar protein FliJ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_29 100.0 0.0 fliI VF0273 Flagella Motility VFC0204 (fliI) flagellum-specific ATP synthase FliI [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_30 99.254 0.0 fliH VF0273 Flagella Motility VFC0204 (fliH) flagellar assembly protein H [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_31 100.0 0.0 fliG VF0273 Flagella Motility VFC0204 (fliG) flagellar motor switch protein G [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_32 100.0 0.0 fliF VF0273 Flagella Motility VFC0204 (fliF) flagellar M-ring protein FliF [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_33 100.0 7.9E-76 fliE VF0273 Flagella Motility VFC0204 (fliE) flagellar hook-basal body complex protein FliE [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_34 99.789 0.0 fleR VF0273 Flagella Motility VFC0204 (fleR) two-component response regulator [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_35 99.751 0.0 fleS VF0273 Flagella Motility VFC0204 (fleS) two-component sensor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_36 99.796 0.0 fleQ VF0273 Flagella Motility VFC0204 (fleQ) transcriptional regulator FleQ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_37 100.0 6.91E-68 fleP/fliT VF0273 Flagella Motility VFC0204 (fleP/fliT) flagellar protein FliT [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_38 99.206 2.72E-88 fliS VF0273 Flagella Motility VFC0204 (fliS) flagellar protein FliS [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_39 99.789 0.0 fliD VF0273 Flagella Motility VFC0204 (fliD) flagellar capping protein FliD [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_40 99.187 6.66E-84 fleI/flaG VF0273 Flagella Motility VFC0204 (fleI/flaG) flagellar protein FlaG [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000430.1_41 99.795 0.0 fliC VF0273 Flagella Motility VFC0204 (fliC) B-type flagellin [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000429.1_8 100.0 2.45E-96 rhlC VF0089 Rhamnolipid Immune modulation VFC0258 Nonenzyme glycolipid (rhlC) rhamnosyltransferase 2 [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000428.1_1 98.746 0.0 toxA VF0086 ExoA Exotoxin VFC0235 Secreted by type II secretion pathway; transported to the endoplasmic reticulum (ER) via a coat protein COPI-dependent retrograde pathway dependent on a KDEL motif (toxA) exotoxin A precursor [ExoA (VF0086) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000421.1_20 68.803 2.2E-110 bfmR VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
ABKZ01000415.1_20 99.582 0.0 aprA VF0090 Alkaline protease Exoenzyme VFC0251 Secreted by type I secretion pathway (aprA) alkaline metalloproteinase precursor [Alkaline protease (VF0090) - Exoenzyme (VFC0251)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_21 100.0 2.34E-115 PA1464 VF0273 Flagella Motility VFC0204 (PA1464) purine-binding chemotaxis protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_24 99.662 0.0 motD VF0273 Flagella Motility VFC0204 (motD) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_25 100.0 9.14E-176 motC VF0273 Flagella Motility VFC0204 (motC) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_26 98.641 0.0 PA1459 VF0273 Flagella Motility VFC0204 (PA1459) chemotaxis-specific methylesterase [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_27 99.336 0.0 PA1458 VF0273 Flagella Motility VFC0204 (PA1458) two-component sensor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_28 100.0 0.0 cheZ VF0273 Flagella Motility VFC0204 (cheZ) protein phosphatase CheZ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_29 100.0 5.08E-90 cheY VF0273 Flagella Motility VFC0204 (cheY) chemotaxis protein CheY [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_30 100.0 3.38E-177 fliA VF0273 Flagella Motility VFC0204 (fliA) flagellar biosynthesis sigma factor FliA [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_31 100.0 0.0 fleN VF0273 Flagella Motility VFC0204 (fleN) flagellar synthesis regulator FleN [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_32 99.068 0.0 flhF VF0273 Flagella Motility VFC0204 (flhF) flagellar biosynthesis protein FlhF [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_33 99.859 0.0 flhA VF0273 Flagella Motility VFC0204 (flhA) flagellar biosynthesis protein FlhA [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_36 100.0 0.0 flhB VF0273 Flagella Motility VFC0204 (flhB) flagellar biosynthetic protein FlhB [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_37 99.612 3.26E-180 fliR VF0273 Flagella Motility VFC0204 (fliR) flagellar biosynthetic protein FliR [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_38 100.0 1.48E-57 fliQ VF0273 Flagella Motility VFC0204 (fliQ) flagellar biosynthetic protein FliQ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_39 100.0 0.0 fliP VF0273 Flagella Motility VFC0204 (fliP) flagellar biosynthetic protein FliP [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_40 100.0 3.57E-103 fliO VF0273 Flagella Motility VFC0204 (fliO) flagellar protein FliO [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_41 100.0 1.09E-111 fliN VF0273 Flagella Motility VFC0204 (fliN) flagellar motor switch protein FliN [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_42 100.0 0.0 fliM VF0273 Flagella Motility VFC0204 (fliM) flagellar motor switch protein FliM [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_43 100.0 2.92E-125 fliL VF0273 Flagella Motility VFC0204 (fliL) flagellar basal body protein FliL [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_44 97.424 0.0 fliK VF0273 Flagella Motility VFC0204 (fliK) flagellar hook-length control protein FliK [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_53 100.0 1.49E-152 lasI VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (lasI) autoinducer synthesis protein LasI [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000401.1_55 100.0 0.0 lasR VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (lasR) transcriptional regulator LasR [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000400.1_21 100.0 1.69E-130 hcpA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (hcpA) Hcp family type VI secretion system effector [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000400.1_22 99.05 0.0 vgrG VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (vgrG) type VI secretion system tip protein VgrG [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000391.1_1 100.0 1.1E-29 hcpA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (hcpA) Hcp family type VI secretion system effector [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000390.1_1 100.0 1.55E-92 hcpA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (hcpA) Hcp family type VI secretion system effector [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_12 98.784 0.0 stk1 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (stk1) serine-threonine kinase Stk1 [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_13 99.587 3.93E-175 stp1 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (stp1) serine/threonine phosphoprotein phosphatase Stp1 [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_14 99.574 0.0 tssM VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssM) type VI secretion system membrane subunit TssM [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_15 100.0 0.0 icmH/tssL VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (icmH/tssL) type IVB secretion system protein IcmH/DotU [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_16 99.549 0.0 tssK VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssK) type VI secretion system baseplate subunit TssK [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_17 99.405 4.09E-118 tssJ VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssJ) type VI secretion system lipoprotein TssJ [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_18 97.229 0.0 PA1665 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (PA1665) hypothetical protein [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_19 100.0 2.58E-30 PA1664 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (PA1664) hypothetical protein [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_20 99.404 0.0 PA1663 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (PA1663) transcriptional regulator [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_21 99.429 0.0 tssH VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssH) type VI secretion system ATPase TssH [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_22 99.403 0.0 tssG VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssG) type VI secretion system baseplate subunit TssG [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_23 99.62 0.0 tssF VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssF) type VI secretion system baseplate subunit TssF [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_24 99.259 2.13E-96 tssE VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssE) type VI secretion system baseplate subunit TssE [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_25 100.0 0.0 tssC VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssC) type VI secretion system contractile sheath large subunit [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_26 99.405 4.92E-119 tssB VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssB) type VI secretion system contractile sheath small subunit [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000388.1_27 99.807 0.0 tssA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssA) type VI secretion system protein TssA [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000386.1_1 99.242 1.48E-89 pscP VF0083 TTSS Effector delivery system VFC0086 (pscP) type III secretion system protein PscP [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000386.1_2 99.029 0.0 pscQ VF0083 TTSS Effector delivery system VFC0086 (pscQ) type III secretion system protein PscQ [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000386.1_3 100.0 1.53E-157 pscR VF0083 TTSS Effector delivery system VFC0086 (pscR) type III secretion system protein PscR [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000386.1_4 100.0 1.14E-57 pscS VF0083 TTSS Effector delivery system VFC0086 (pscS) type III secretion system protein PscS [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000386.1_5 99.237 0.0 pscT VF0083 TTSS Effector delivery system VFC0086 (pscT) type III secretion system protein PscT [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000386.1_6 99.427 0.0 pscU VF0083 TTSS Effector delivery system VFC0086 (pscU) type III secretion system protein PscU [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_14 99.065 5.62E-150 pscL VF0083 TTSS Effector delivery system VFC0086 (pscL) type III secretion systemt protein PscL [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_15 98.558 8.74E-146 pscK VF0083 TTSS Effector delivery system VFC0086 (pscK) type III secretion system protein PscK [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_16 99.59 3.84E-178 pscJ VF0083 TTSS Effector delivery system VFC0086 (pscJ) type III secretion system inner MS ring protein [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_17 98.214 2.55E-77 pscI VF0083 TTSS Effector delivery system VFC0086 (pscI) type III secretion system inner rod protein PscI [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_18 100.0 1.52E-98 pscH VF0083 TTSS Effector delivery system VFC0086 (pscH) type III secretion system protein PscH [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_19 99.13 8.11E-80 pscG VF0083 TTSS Effector delivery system VFC0086 (pscG) type III secretion system chaperone PscG for PscF [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_20 100.0 3.43E-58 pscF VF0083 TTSS Effector delivery system VFC0086 (pscF) type III secretion system needle filament protein PscF [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_21 97.015 1.96E-40 pscE VF0083 TTSS Effector delivery system VFC0086 (pscE) type III secretion system cochaperone PscE for PscG [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_22 98.611 0.0 pscD VF0083 TTSS Effector delivery system VFC0086 (pscD) type III secretion system basal body protein PscD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_23 99.833 0.0 pscC VF0083 TTSS Effector delivery system VFC0086 (pscC) type III secretion system secretin PscC [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_24 99.286 1.56E-92 pscB VF0083 TTSS Effector delivery system VFC0086 (pscB) type III secretion system protein PscB [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_25 99.275 0.0 exsD VF0083 TTSS Effector delivery system VFC0086 (exsD) type III secretion system regulatory protein ExsD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_26 100.0 0.0 exsA VF0083 TTSS Effector delivery system VFC0086 (exsA) type III secretion system regulatory protein ExsA [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_27 98.54 6.87E-95 exsB VF0083 TTSS Effector delivery system VFC0086 (exsB) type III secretion system pilotin ExsB [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_28 97.531 1.5E-52 exsE VF0083 TTSS Effector delivery system VFC0086 (exsE) type III secretion system regulatory protein ExsE [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_29 99.31 3.77E-102 exsC VF0083 TTSS Effector delivery system VFC0086 (exsC) type III secretion system regulatory protein ExsC [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_30 98.644 0.0 popD VF0083 TTSS Effector delivery system VFC0086 (popD) type III secretion system hydrophobic translocator, pore protein PopD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_31 98.974 0.0 popB VF0083 TTSS Effector delivery system VFC0086 (popB) type III secretion system hydrophobic translocator, pore protein PopB [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_32 98.214 2.13E-118 pcrH VF0083 TTSS Effector delivery system VFC0086 (pcrH) type III secretion system regulatory protein PcrH [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_33 98.98 0.0 pcrV VF0083 TTSS Effector delivery system VFC0086 (pcrV) type III secretion system hydrophilic translocator, needle tip protein PcrV [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_34 98.98 5.31E-64 pcrG VF0083 TTSS Effector delivery system VFC0086 (pcrG) type III secretion system cytoplasmic regulator PcrG [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_35 100.0 6.66E-103 pcrR VF0083 TTSS Effector delivery system VFC0086 (pcrR) type III secretion system regulatory protein PcrR [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_36 100.0 0.0 pcrD VF0083 TTSS Effector delivery system VFC0086 (pcrD) type III secretion system protein PcrD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_37 98.165 1.22E-68 pcr4 VF0083 TTSS Effector delivery system VFC0086 (pcr4) type III secretion system protein Pcr4 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_38 99.174 3.01E-83 pcr3 VF0083 TTSS Effector delivery system VFC0086 (pcr3) type III secretion system protein Pcr3 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_39 99.187 6.22E-85 pcr2 VF0083 TTSS Effector delivery system VFC0086 (pcr2) type III secretion system protein Pcr2 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_40 100.0 1.02E-63 pcr1 VF0083 TTSS Effector delivery system VFC0086 (pcr1) type III secretion system protein Pcr1 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_41 100.0 0.0 popN VF0083 TTSS Effector delivery system VFC0086 (popN) type III secretion system outer membrane protein PopN [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_42 99.534 0.0 pscN VF0083 TTSS Effector delivery system VFC0086 (pscN) type III secretion system ATPase PscN [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000385.1_43 99.367 1.86E-103 pscO VF0083 TTSS Effector delivery system VFC0086 (pscO) type III secretion system protein PscO [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000381.1_5 62.827 8.71E-91 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
ABKZ01000379.1_13 100.0 3.28E-114 tse1 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse1) type VI secretion system effector Tse1, peptidoglycanhydrolase [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000379.1_37 99.822 0.0 fimL VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimL) hypothetical protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000377.1_4 97.847 0.0 lasA VF0088 LasA Effector delivery system VFC0086 Secreted by type II secretion pathway (lasA) LasA protease precursor [LasA (VF0088) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000374.1_1 100.0 8.82E-63 phzC1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzC1) phenazine biosynthesis protein PhzC [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000374.1_2 100.0 3.64E-123 phzB2 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzB2) phenazine biosynthesis protein PhzB [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000374.1_3 99.383 6.05E-122 phzA2 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzA2) phenazine biosynthesis protein PhzA [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000373.1_1 100.0 2.9E-131 phzC1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzC1) phenazine biosynthesis protein PhzC [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000372.1_1 100.0 8.77E-14 phzD1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzD1) phenazine biosynthesis protein PhzD, isochorismatase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000372.1_2 99.187 1.18E-84 phzC1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzC1) phenazine biosynthesis protein PhzC [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000371.1_1 99.563 1.34E-159 phzE1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzE1) phenazine biosynthesis protein PhzE [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000371.1_2 100.0 3.63E-133 phzD1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzD1) phenazine biosynthesis protein PhzD, isochorismatase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000370.1_1 100.0 2.01E-86 phzG2 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzG2) pyridoxamine 5'-phosphate oxidase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000370.1_2 100.0 0.0 phzF1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzF1) phenazine biosynthesis protein PhzF, isomerase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000370.1_3 99.723 0.0 phzE1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzE1) phenazine biosynthesis protein PhzE [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000369.1_12 98.876 9.83E-63 phzG2 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzG2) pyridoxamine 5'-phosphate oxidase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000362.1_5 95.706 3.08E-105 fapA VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapA) periplasmic accessory protein FapA [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000362.1_6 98.942 5.84E-130 fapB VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapB) minor amyloid subunit FapB [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000362.1_7 99.412 0.0 fapC VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapC) major amyloid subunit FapC [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000362.1_8 99.115 6.48E-167 fapD VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapD) periplasmic accessory protein FapD [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000362.1_9 98.8 6.28E-179 fapE VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapE) chaprone FapE [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000362.1_10 100.0 0.0 fapF VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapF) outer membrane secretin FapF [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000330.1_1 98.148 0.0 exoY VF0853 TTSS secreted effectors Effector delivery system VFC0086 (exoY) type III secretion system effector ExoY, adenylate cyclase [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000319.1_1 95.745 5.3E-27 ptxR VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (ptxR) transcriptional regulator PtxR [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000319.1_2 99.07 5.88E-157 pvcD VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcD) paerucumarin biosynthesis protein PvcD [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000319.1_3 99.6 0.0 pvcC VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcC) paerucumarin biosynthesis protein PvcC [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000319.1_4 99.656 0.0 pvcB VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcB) paerucumarin biosynthesis protein PvcB [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000319.1_5 99.39 0.0 pvcA VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcA) paerucumarin biosynthesis protein PvcA [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000318.1_22 100.0 0.0 ptxR VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (ptxR) transcriptional regulator PtxR [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000309.1_2 65.242 6.11E-161 PA2359 VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (PA2359) transcriptional regulator [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000308.1_1 98.75 1.21E-49 tssM VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssM) type VI secretion system membrane subunit [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000308.1_2 98.361 0.0 tssA VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssA) type VI secretion system protein TssA [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000308.1_3 99.446 0.0 PA2359 VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (PA2359) transcriptional regulator [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000307.1_1 100.0 1.2E-37 icmH/tssL VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (icmH/tssL) DotU/TssL family secretion system protein [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000307.1_2 97.903 0.0 tssM VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssM) type VI secretion system membrane subunit [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_1 100.0 4.37E-28 pvdA VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdA) L-ornithine N5-oxygenase PvdA [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_2 99.738 0.0 pvdQ VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdQ) 3-oxo-C12-homoserine lactone acylase PvdQ [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_3 100.0 2.14E-74 PA2384 VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (PA2384) hypothetical protein [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_4 99.346 0.0 PA2383 VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (PA2383) transcriptional regulator [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_14 96.257 0.0 tssI VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssI) type VI secretion system tip protein VgrG [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_17 99.529 0.0 tssH VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssH) type VI secretion system ATPase TssH [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_18 99.408 0.0 tssG VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssG) type VI secretion system baseplate subunit TssG [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_19 99.832 0.0 tssF VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssF) type VI secretion system baseplate subunit TssF [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_20 97.163 6.46E-94 tssE VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssE) type VI secretion system baseplate subunit TssE [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_21 100.0 1.26E-122 hcp/tssD VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (hcp/tssD) Hcp family type VI secretion system effector [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_22 100.0 0.0 tssC VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssC) type VI secretion system contractile sheath large subunit [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_23 100.0 1.72E-129 tssB VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssB) type VI secretion system contractile sheath small subunit [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_24 99.363 3.23E-115 PA2364 VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (PA2364) hypothetical protein [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_25 98.871 0.0 tssK VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssK) type VI secretion system baseplate subunit TssK [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000306.1_26 99.476 1.47E-136 icmH/tssL VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (icmH/tssL) DotU/TssL family secretion system protein [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000305.1_1 99.291 5.08E-99 pvdP VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdP) tyrosinase required for pyoverdine maturation [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000304.1_1 97.826 2.95E-62 pvdM VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdM) dipeptidase precursor [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000303.1_1 99.248 0.0 pvdO VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdO) pyoverdine biosynthesis protein PvdO [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000303.1_2 99.297 0.0 pvdN VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdN) pyoverdine biosynthesis protein PvdN [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000303.1_3 100.0 8.41E-166 pvdM VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdM) dipeptidase precursor [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000302.1_1 99.091 3.5E-68 pvdI VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdI) peptide synthase [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000301.1_1 97.826 4.59E-55 pvdI VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdI) peptide synthase [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000300.1_1 98.736 0.0 pvdI VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdI) peptide synthase [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000299.1_7 100.0 0.0 pvdH VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdH) diaminobutyrate-2-oxoglutarate aminotransferase PvdH [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000299.1_8 100.0 4.21E-52 mbtH-like VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (mbtH-like) MbtH-like protein from the pyoverdine cluster [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000299.1_18 99.411 0.0 pvdI VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdI) peptide synthase [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000296.1_1 99.386 0.0 pvdL VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdL) peptide synthase PvdL [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000295.1_1 100.0 1.33E-134 pvdS VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdS) extracytoplasmic-function sigma-70 factor [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000295.1_2 99.606 0.0 pvdG VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdG) pyoverdine biosynthesis protein PvdG [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000295.1_3 99.63 0.0 pvdL VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdL) peptide synthase PvdL [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000277.1_10 67.395 0.0 adeG VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
ABKZ01000224.1_2 99.544 0.0 tse5/rhsP1 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse5/rhsP1) Toxin protein Tse5 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000223.1_1 96.0 2.84E-84 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000222.1_1 88.929 0.0 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000221.1_1 80.0 1.47E-55 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000219.1_2 63.725 0.0 fepA VF0562 Ent Nutritional/Metabolic factor VFC0272 Various iron acquisition systems in Klebsiella are needed to overcome host defenses in different anatomical compartments. (fepA) outer membrane receptor FepA [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABKZ01000216.1_2 98.734 8.48E-115 tse2 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse2) type VI secretion system effector Tse2 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000206.1_4 99.487 4.22E-133 tse4 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse4) Toxin protein Tse4 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000198.1_4 100.0 1.8E-85 pilZ VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilZ) type 4 fimbrial biogenesis protein PilZ [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000197.1_23 64.228 2.73E-106 flmH VF0473 Polar flagella Motility VFC0204 Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments (flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
ABKZ01000197.1_24 65.753 1.64E-28 acpXL VF0367 LPS Immune modulation VFC0258 Brucella possesses a non-classical LPS as compared with the so-called classical LPS from enterobacteria such as Escherichia coli. B. abortus lipid A possesses a diaminoglucose backbone (rather than glucosamine), and acyl groups are longer (C28 rather than C12 and C16) and are only linked to the core by amide bounds (rather than ester and amide bonds).; In contrast to enterobacterial LPSs, Brucella LPS is several-hundred-times less active and toxic than E. coli LPS.; this is an evolutionary adaptation to an intracellular lifestyle, low endotoxic activity is shared by other intracellular pathogens such as Bartonella and Legionella. (acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M] Brucella melitensis
ABKZ01000186.1_1 100.0 8.69E-38 xcpX VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpX) general secretion pathway protein K [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000186.1_2 99.476 0.0 xcpY VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpY) general secretion pathway protein L [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000186.1_3 100.0 1.14E-122 xcpZ VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpZ) general secretion pathway protein M [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_1 95.0 9.16E-20 xcpQ VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpQ) general secretion pathway protein D [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_2 99.541 3.11E-158 xcpP VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpP) secretion protein XcpP [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_3 100.0 0.0 xcpR VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpR) general secretion pathway protein E [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_4 100.0 0.0 xcpS VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpS) general secretion pathway protein F [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_5 99.324 8.73E-107 xcpT VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpT) general secretion pathway protein G [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_6 99.419 1.04E-120 xcpU VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpU) general secretion pathway protein H [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_7 99.225 1.07E-89 xcpV VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpV) general secretion pathway protein I [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_8 100.0 1.07E-173 xcpW VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpW) general secretion pathway protein J [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000185.1_9 99.587 5.03E-177 xcpX VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpX) general secretion pathway protein K [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000184.1_1 99.44 0.0 xcpQ VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpQ) general secretion pathway protein D [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000181.1_1 100.0 0.0 wbpM VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000181.1_27 98.81 0.0 fimV VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimV) a polar peptidoglycan-binding protein involved in type IV pilus assembly [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000180.1_1 99.259 3.77E-91 wbpM VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000164.1_5 99.359 3.75E-107 flgN VF0273 Flagella Motility VFC0204 (flgN) flagella synthesis protein FlgN [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000164.1_6 100.0 2.75E-75 flgM VF0273 Flagella Motility VFC0204 (flgM) negative regulator of flagellin synthesis [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000164.1_7 98.707 2.72E-169 flgA VF0273 Flagella Motility VFC0204 (flgA) flagellar basal body P-ring biosynthesis protein FlgA [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000164.1_8 99.355 0.0 PA3349 VF0273 Flagella Motility VFC0204 (PA3349) chemotaxis protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000164.1_9 100.0 0.0 PA3348 VF0273 Flagella Motility VFC0204 (PA3348) chemotaxis protein methyltransferase [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000152.1_3 100.0 0.0 tse3 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse3) type VI secretion system effector Tse3, glycoside hydrolase [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000152.1_8 99.661 0.0 rhlA VF0089 Rhamnolipid Immune modulation VFC0258 Nonenzyme glycolipid (rhlA) rhamnosyltransferase chain A [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000152.1_9 100.0 0.0 rhlB VF0089 Rhamnolipid Immune modulation VFC0258 Nonenzyme glycolipid (rhlB) rhamnosyltransferase chain B [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000152.1_10 100.0 0.0 rhlR VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (rhlR) transcriptional regulator RhlR [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000152.1_11 99.005 5.69E-150 rhlI VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (rhlI) autoinducer synthesis protein RhlL [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000150.1_5 99.456 0.0 pldA/tle5a VF0915 HSI-2 T6SS secreted effectors Effector delivery system VFC0086 (pldA/tle5a) phospholipase D [HSI-2 T6SS secreted effectors (VF0915) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_24 100.0 0.0 algA VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algA) phosphomannose isomerase / guanosine 5'-diphospho-D-mannose pyrophosphorylase [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_25 100.0 2.36E-159 algF VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algF) alginate o-acetyltransferase AlgF [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_26 100.0 0.0 algJ VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algJ) alginate o-acetyltransferase AlgJ [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_27 99.423 0.0 algI VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algI) alginate o-acetyltransferase AlgI [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_28 99.728 0.0 algL VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algL) poly(beta-d-mannuronate) lyase precursor AlgL [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_29 99.578 0.0 algX VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algX) alginate biosynthesis protein AlgX [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_30 99.816 0.0 algG VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algG) outer membrane protein AlgE [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_31 99.796 0.0 algE VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algE) alginate biosynthetic protein AlgK precursor [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_32 99.789 0.0 algK VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algK) alginate biosynthesis protein Alg44 [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_33 100.0 0.0 alg44 VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (alg44) alginate biosynthesis protein Alg8 [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_34 100.0 0.0 alg8 VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (alg8) alginate-c5-mannuronan-epimerase AlgG [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_35 100.0 0.0 algD VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algD) GDP-mannose 6-dehydrogenase AlgD [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000149.1_49 99.688 0.0 motY VF0273 Flagella Motility VFC0204 (motY) probable outer membrane protein precursor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000145.1_12 99.701 0.0 rpoS VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (rpoS) RNA polymerase sigma factor RpoS [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000144.1_8 66.784 3.34E-145 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABKZ01000143.1_6 61.017 4.02E-20 lpxB VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lpxB) lipid-A-disaccharide synthase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
ABKZ01000142.1_15 99.111 0.0 mucP VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucP) metalloprotease protease [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000139.1_10 98.996 0.0 lasB VF0087 LasB Effector delivery system VFC0086 Secreted by type II secretion pathway (lasB) elastase LasB [LasB (VF0087) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000134.1_20 99.603 0.0 pilF VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilF) type 4 fimbrial biogenesis protein PilF [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000130.1_10 99.138 4.26E-82 spcS VF0083 TTSS Effector delivery system VFC0086 (spcS) chaperone for exoS [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000107.1_1 98.876 6.36E-61 mucE VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucE) small envelope protein MucE [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000093.1_4 61.328 3.23E-112 fepC VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
ABKZ01000089.1_1 100.0 1.27E-84 phzB1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzB1) phenazine biosynthesis protein PhzB [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000089.1_2 98.765 1.56E-120 phzA1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzA1) phenazine biosynthesis protein PhzA [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000089.1_3 100.0 0.0 phzM VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzM) phenazine-specific methyltransferase PhzM (adenosylmethionine dependent methyltransferase) [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000088.1_1 100.0 5.17E-104 phzC1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzC1) phenazine biosynthesis protein PhzC [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000088.1_2 97.826 1.64E-28 phzB1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzB1) phenazine biosynthesis protein PhzB [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000087.1_1 99.167 2.39E-175 phzC1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzC1) phenazine biosynthesis protein PhzC [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000086.1_1 100.0 9.81E-124 phzG2 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzG2) pyridoxamine 5'-phosphate oxidase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000086.1_2 100.0 0.0 phzF1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzF1) phenazine biosynthesis protein PhzF, isomerase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000086.1_3 99.681 0.0 phzE1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzE1) phenazine biosynthesis protein PhzE [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000086.1_4 100.0 6.37E-155 phzD1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzD1) phenazine biosynthesis protein PhzD, isochorismatase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000085.1_1 99.005 0.0 phzS VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzS) flavin dependent hydroxylase PhzS [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000085.1_2 100.0 2.21E-28 phzG1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzG1) phenazine biosynthesis protein PhzG, pyridoxamine 5'-phosphate oxidase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_1 98.02 0.0 pchF VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchF) pyochelin synthetase PchF [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_2 99.14 0.0 pchG VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchG) pyochelin biosynthetic protein PchG [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_3 99.649 0.0 pchH VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchH) ABC transporter ATP-binding protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_4 98.432 0.0 pchI VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchI) ABC transporter ATP-binding protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_5 100.0 0.0 fptA VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (fptA) Fe(III)-pyochelin receptor precursor [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_6 95.699 4.91E-53 PA4220 VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (PA4220) hypothetical protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_7 99.002 0.0 PA4219 VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (PA4219) hypothetical protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000084.1_8 99.758 0.0 PA4218 VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (PA4218) transporter [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000083.1_1 100.0 1.84E-51 pchF VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchF) pyochelin synthetase PchF [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000082.1_1 99.552 0.0 pchF VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchF) pyochelin synthetase PchF [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000081.1_12 80.101 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABKZ01000081.1_40 69.102 0.0 katA VF0454 KatA Stress survival VFC0282 (katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58] Neisseria meningitidis
ABKZ01000081.1_45 99.79 0.0 pchA VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchA) salicylate biosynthesis isochorismate synthase PchA [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000081.1_46 100.0 1.42E-71 pchB VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchB) salicylate biosynthesis protein PchB [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000081.1_47 99.602 3.02E-177 pchC VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchC) pyochelin biosynthetic protein PchC [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000081.1_48 98.905 0.0 pchD VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchD) pyochelin biosynthesis protein PchD [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000081.1_49 99.662 0.0 pchR VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchR) transcriptional regulator PchR [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000081.1_50 98.609 0.0 pchE VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchE) dihydroaeruginoic acid synthetase PchE [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000081.1_51 99.071 0.0 pchF VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchF) pyochelin synthetase PchF [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000080.1_1 79.36 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABKZ01000079.1_4 81.818 1.17E-19 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABKZ01000075.1_3 100.0 4.07E-160 vfr VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (vfr) cAMP-regulatory protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000071.1_9 63.801 7.18E-99 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
ABKZ01000046.1_69 100.0 0.0 pilT VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilT) twitching motility protein PilT [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_70 99.738 0.0 pilU VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilU) twitching motility protein PilU [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_82 100.0 2.88E-98 pilG VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilG) twitching motility protein PilG [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_83 100.0 3.45E-77 pilH VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilH) twitching motility protein PilH [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_84 100.0 6.64E-130 pilI VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilI) twitching motility protein PilI [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_85 99.853 0.0 pilJ VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilJ) twitching motility protein PilJ [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_86 99.656 0.0 pilK VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilK) methyltransferase PilK [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_87 98.91 0.0 chpA VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpA) still frameshift probable component of chemotactic signal transduction system [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_88 99.417 0.0 chpB VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpB) probable methylesterase [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_89 98.214 1.02E-115 chpC VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpC) probable chemotaxis protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_90 100.0 0.0 chpD VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpD) probable transcriptional regulator [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_91 99.507 3.49E-141 chpE VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpE) probable chemotaxis protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000046.1_100 71.344 0.0 acrB VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
ABKZ01000036.1_1 100.0 1.69E-130 hcpA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (hcpA) Hcp family type VI secretion system effector [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000035.1_1 99.608 0.0 vgrG2b VF0915 HSI-2 T6SS secreted effectors Effector delivery system VFC0086 (vgrG2b) Type VI secretion system spike protein VgrG2b; metallopeptidase effector VgrG2b [HSI-2 T6SS secreted effectors (VF0915) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000034.1_1 98.734 2.19E-46 vgrG2b VF0915 HSI-2 T6SS secreted effectors Effector delivery system VFC0086 (vgrG2b) Type VI secretion system spike protein VgrG2b; metallopeptidase effector VgrG2b [HSI-2 T6SS secreted effectors (VF0915) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000033.1_12 98.956 0.0 vgrG2b VF0915 HSI-2 T6SS secreted effectors Effector delivery system VFC0086 (vgrG2b) Type VI secretion system spike protein VgrG2b; metallopeptidase effector VgrG2b [HSI-2 T6SS secreted effectors (VF0915) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000026.1_36 66.242 9.28E-71 cheW VF0430 Flagella Motility VFC0204 (cheW) chemotaxis protein CheW [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243] Burkholderia pseudomallei
ABKZ01000020.1_1 100.0 2.02E-73 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000019.1_1 98.565 5.23E-145 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000018.1_1 99.519 2.53E-143 tse6 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse6) NAD(P)(+) glycohydrolase toxin Tse6 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000018.1_3 99.268 0.0 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_1 98.905 0.0 fha1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (fha1) type VI secretion system forkhead-associated protein Fha1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_2 98.256 0.0 hsiA1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiA1) type VI secretion system hcp secretion island protein HsiA1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_3 100.0 4.29E-125 hsiB1/vipA/tssB VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiB1/vipA/tssB) type VI secretion system tubule-forming protein VipA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_4 100.0 0.0 hsiC1/vipB/tssC VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiC1/vipB/tssC) type VI secretion system tubule-forming protein VipB [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_5 100.0 2.12E-120 hcp1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hcp1) type VI secretion system substrate Hcp1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_6 100.0 0.0 hsiE1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiE1) type VI secretion system hcp secretion island protein HsiE1, interacting with HsiB1 to form a novel subcomplex of the T6SS [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_7 99.408 1.65E-120 hsiF1/tssE VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiF1/tssE) type VI secretion system hcp secretion island protein HsiF1, a gp25-like protein, but not exhibit lysozyme activity [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_8 99.677 0.0 hsiG1/tssF VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiG1/tssF) type VI secretion system hcp secretion island protein HsiG1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_9 100.0 0.0 hsiH1/tssG VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiH1/tssG) type VI secretion system hcp secretion island protein HsiH1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_10 99.667 0.0 clpV1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (clpV1) type VI secretion system AAA+ family ATPase [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000017.1_11 99.689 0.0 vgrG1a VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1a) type VI secretion system substrate VgrG1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_17 98.355 0.0 tagQ VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagQ) type VI secretiona ssociated protein TagQ, outer membrane lipoprotein [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_18 99.298 0.0 tagR VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagR) type VI secretion associated protein TagR, positively regulates PpkA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_19 99.306 0.0 tagS VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagS) type VI secretion associated protein TagS, forming a stable inner membrane complex with TagT [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_20 94.059 2.73E-58 tagS VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagS) type VI secretion associated protein TagS, forming a stable inner membrane complex with TagT [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_21 98.745 1.76E-166 tagT VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagT) type VI secretion associated protein TagT, ATP-binding component of ABC transporter [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_22 99.516 0.0 ppkA VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (ppkA) serine/threonine protein kinase PpkA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_23 99.587 2.45E-176 pppA VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (pppA) Pseudomonas protein phosphatase PppA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_24 99.558 5.97E-163 tagF/pppB VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagF/pppB) Pseudomonas protein phosphatase PppB [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_25 99.546 0.0 icmF1/tssM1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (icmF1/tssM1) type VI secretion system protein IcmF1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_26 100.0 0.0 dotU1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (dotU1) type VI secretion system protein DotU [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_27 99.775 0.0 hsiJ1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiJ1) type VI secretion system hcp secretion island protein HsiJ1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_28 100.0 9.67E-112 lip1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (lip1) lipoprotein [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000016.1_29 99.548 2.81E-155 fha1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (fha1) type VI secretion system forkhead-associated protein Fha1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000015.1_1 99.672 0.0 phzH VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzH) phenazine-modifying enzyme [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
ABKZ01000014.1_3 99.781 0.0 exoT VF0853 TTSS secreted effectors Effector delivery system VFC0086 (exoT) type III secretion system effector ExoT, ADP ribosyltransferase activity and GTPase-activating protein activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa