| AEOW01000007.1_1 |
78.641 |
3.9E-57 |
tufA |
VF0460 |
EF-Tu |
Adherence |
VFC0001 |
|
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| GL636781.1_9 |
66.23 |
1.07E-156 |
lpxL |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636786.1_2 |
97.377 |
0.0 |
ata |
VF1333 |
Ata |
Adherence |
VFC0001 |
|
(ata) trimeric autotransporter adhesin Ata [Ata (VF1333) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| AEOW01000066.1_1 |
96.203 |
6.4E-175 |
abaR |
VF0471 |
Quorom sensing |
Biofilm |
VFC0271 |
|
(abaR) DNA-binding HTH domain-containing protein [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636789.1_7 |
69.432 |
1.41E-91 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| AEOW01000088.1_1 |
76.512 |
3.05E-147 |
tufA |
VF0460 |
EF-Tu |
Adherence |
VFC0001 |
|
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| GL636797.1_2 |
65.145 |
1.25E-112 |
carB |
VF0558 |
Pyrimidine biosynthesis |
Nutritional/Metabolic factor |
VFC0272 |
CarB, CarA, and PyrB encode the large and small subunits of carbamoylphosphate synthetase and aspartate carbamoyl transferase, respectively. These enzymes catalyze the first two steps in the pyrimidine nucleotide biosynthetic pathway in many bacteria, including Francisella, and are required for the virulence of several pathogens, including Salmonella and E. coli |
(carB) carbamoyl phosphate synthase large subunit [Pyrimidine biosynthesis (VF0558) - Nutritional/Metabolic factor (VFC0272)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| GL636800.1_34 |
66.359 |
1.69E-98 |
rpe |
VF0543 |
Capsule |
Immune modulation |
VFC0258 |
Group 4 capsule; high molecular weight (HMW) O-antigen capsule |
(rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| GL636801.1_3 |
64.591 |
1.61E-105 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636801.1_4 |
75.698 |
0.0 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636801.1_5 |
77.512 |
1.85E-112 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| AEOW01000169.1_1 |
100.0 |
4.4E-120 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636810.1_55 |
99.744 |
0.0 |
lpxB |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpxB) lipid-A-disaccharide synthase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| AEOW01000233.1_1 |
98.592 |
6.04E-98 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636812.1_15 |
69.202 |
0.0 |
htpB |
VF0159 |
Hsp60 |
Adherence |
VFC0001 |
|
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] |
Legionella pneumophila |
| GL636819.1_1 |
73.626 |
3.17E-92 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636819.1_2 |
67.059 |
6.01E-37 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636819.1_3 |
74.51 |
0.0 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636823.1_6 |
98.201 |
0.0 |
basJ |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basJ) acinetobactin biosynthesis protein BasJ [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636823.1_7 |
97.211 |
0.0 |
basI |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basI) phosphopantetheinyl transferase component of acinetobactin biosynthesis protein BasI [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636823.1_8 |
97.541 |
0.0 |
basH |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basH) non-ribosomal peptide biosynthesis thioesterase BasH [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636823.1_9 |
97.363 |
0.0 |
barB |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(barB) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636823.1_10 |
96.269 |
0.0 |
barA |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(barA) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636823.1_12 |
98.873 |
0.0 |
basG |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636830.1_30 |
100.0 |
0.0 |
plcD |
VF0469 |
Phospholipase D |
Exotoxin |
VFC0235 |
|
(plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636835.1_3 |
99.225 |
2.72E-89 |
pgaB |
VF0472 |
PNAG |
Biofilm |
VFC0271 |
PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. |
(pgaB) poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636835.1_4 |
97.137 |
0.0 |
pgaB |
VF0472 |
PNAG |
Biofilm |
VFC0271 |
PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. |
(pgaB) poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636835.1_6 |
99.676 |
0.0 |
pgaC |
VF0472 |
PNAG |
Biofilm |
VFC0271 |
PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. |
(pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636835.1_7 |
99.351 |
2.22E-112 |
pgaD |
VF0472 |
PNAG |
Biofilm |
VFC0271 |
PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. |
(pgaD) poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636836.1_21 |
100.0 |
0.0 |
lpxM |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpxM) lysophospholipid acyltransferase family protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| AEOW01000415.1_2 |
60.816 |
4.42E-101 |
CBU_1566 |
VF0696 |
T4SS secreted effectors |
Effector delivery system |
VFC0086 |
|
(CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] |
Coxiella burnetii |
| GL636840.1_7 |
61.429 |
2.0E-131 |
kdsA |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| GL636844.1_26 |
100.0 |
6.83E-138 |
abaI |
VF0471 |
Quorom sensing |
Biofilm |
VFC0271 |
|
(abaI) N-acyl-L-homoserine lactone synthetase [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636858.1_13 |
99.374 |
0.0 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_6 |
96.93 |
0.0 |
ACICU_RS00500 |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(ACICU_RS00500) phosphomannomutase/phosphoglucomutase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_8 |
97.03 |
0.0 |
pgi |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(pgi) glucose-6-phosphate isomerase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_10 |
95.952 |
0.0 |
ACICU_RS00485 |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(ACICU_RS00485) nucleotide sugar dehydrogenase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_11 |
87.629 |
0.0 |
galU |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(galU) UTP--glucose-1-phosphate uridylyltransferase GalU [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_12 |
74.257 |
5.15E-110 |
ACICU_RS00475 |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(ACICU_RS00475) sugar transferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_24 |
66.667 |
2.52E-143 |
wbtL |
VF0542 |
LPS |
Immune modulation |
VFC0258 |
The structure of Francisella spp. lipid A is unique in that it is modified by various carbohydrates that greatly reduce TLR4 activation and allow for immune evasion |
(wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| GL636865.1_28 |
64.228 |
5.98E-120 |
rffG |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(rffG) dTDP-glucose 46-dehydratase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| GL636865.1_29 |
86.174 |
0.0 |
tviB |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(tviB) Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_32 |
60.49 |
4.95E-164 |
ACICU_RS00405 |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(ACICU_RS00405) polysaccharide biosynthesis/export family protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_33 |
73.381 |
8.25E-79 |
ACICU_RS00400 |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(ACICU_RS00400) low molecular weight phosphotyrosine protein phosphatase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_34 |
69.85 |
0.0 |
ACICU_RS00395 |
VF0465 |
Capsule |
Immune modulation |
VFC0258 |
A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. |
(ACICU_RS00395) polysaccharide biosynthesis tyrosine autokinase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636865.1_43 |
97.091 |
0.0 |
plc1 |
VF0470 |
Phospholipase C |
Exotoxin |
VFC0235 |
|
(plc1) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_5 |
99.091 |
1.47E-72 |
gspD |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspD) general secretion pathway protein D [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_13 |
99.497 |
0.0 |
gspD |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspD) general secretion pathway protein D [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_14 |
98.347 |
2.66E-84 |
gspC |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspC) general secretion pathway protein C [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_16 |
99.595 |
0.0 |
gspN |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspN) type II secretion system protein N [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_50 |
100.0 |
3.95E-158 |
pbpG |
VF0468 |
PbpG |
Immune modulation |
VFC0258 |
|
(pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_51 |
99.174 |
3.4E-81 |
pbpG |
VF0468 |
PbpG |
Immune modulation |
VFC0258 |
|
(pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_53 |
99.738 |
0.0 |
pilS |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_54 |
95.918 |
9.56E-66 |
pilS |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_55 |
97.207 |
4.3E-121 |
pilR |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilR) sigma-54 dependent transcriptional regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636870.1_56 |
96.791 |
8.11E-135 |
pilR |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilR) sigma-54 dependent transcriptional regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636871.1_26 |
98.383 |
0.0 |
plc2 |
VF0470 |
Phospholipase C |
Exotoxin |
VFC0235 |
|
(plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636872.1_11 |
100.0 |
0.0 |
lpxA |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636872.1_13 |
100.0 |
0.0 |
lpxD |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpxD) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636874.1_8 |
61.0 |
2.5E-34 |
ureA |
VF0050 |
Urease |
Stress survival |
VFC0282 |
|
(ureA) urease alpha subunit UreA [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] |
Helicobacter pylori |
| GL636876.1_4 |
98.311 |
0.0 |
ACICU_RS04565 |
VF0636 |
HemO cluster |
Nutritional/Metabolic factor |
VFC0272 |
|
(ACICU_RS04565) LysR family transcriptional regulator [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636876.1_5 |
84.615 |
3.14E-53 |
ACICU_RS04610 |
VF0636 |
HemO cluster |
Nutritional/Metabolic factor |
VFC0272 |
|
(ACICU_RS04610) hypothetical protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636877.1_46 |
97.902 |
0.0 |
gspO/pilD |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(gspO/pilD) A24 family peptidase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636877.1_47 |
99.755 |
0.0 |
pilC |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilC) type II secretion system F family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636877.1_48 |
99.298 |
0.0 |
pilB |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilB) type IV-A pilus assembly ATPase PilB [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636877.1_94 |
100.0 |
0.0 |
gspF |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspF) general secretion pathway protein F [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636877.1_95 |
99.429 |
1.34E-130 |
gspG |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspG) general secretion pathway protein G [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636878.1_26 |
64.286 |
2.02E-29 |
vfr |
VF0082 |
Type IV pili |
Adherence |
VFC0001 |
PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili |
(vfr) cAMP-regulatory protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] |
Pseudomonas aeruginosa |
| GL636880.1_128 |
98.961 |
0.0 |
bfmS |
VF0463 |
BfmRS |
Regulation |
VFC0301 |
Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions |
(bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636880.1_129 |
100.0 |
8.33E-113 |
bfmS |
VF0463 |
BfmRS |
Regulation |
VFC0301 |
Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions |
(bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636880.1_130 |
100.0 |
3.98E-173 |
bfmR |
VF0463 |
BfmRS |
Regulation |
VFC0301 |
Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions |
(bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636890.1_32 |
98.945 |
0.0 |
gspL |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspL) general secretion pathway protein L [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636890.1_33 |
99.371 |
2.43E-114 |
gspM |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspM) general secretion pathway protein M [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636892.1_5 |
94.92 |
0.0 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636893.1_9 |
99.206 |
0.0 |
gspE2 |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636893.1_10 |
99.457 |
1.19E-133 |
gspE2 |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636895.1_66 |
100.0 |
3.99E-129 |
gspE1 |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspE1) general secretion pathway protein E [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636895.1_67 |
98.107 |
0.0 |
gspE1 |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspE1) general secretion pathway protein E [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636896.1_35 |
62.857 |
1.48E-136 |
acrB |
VF0568 |
AcrAB |
Antimicrobial activity/Competitive advantage |
VFC0325 |
|
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| GL636900.1_1 |
100.0 |
4.81E-21 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636901.1_15 |
64.444 |
2.71E-49 |
msbA |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| GL636901.1_22 |
100.0 |
3.61E-137 |
gspH |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspH) general secretion pathway protein H [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636901.1_23 |
99.206 |
4.39E-90 |
gspI |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspI) general secretion pathway protein I [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636901.1_25 |
98.119 |
0.0 |
gspK |
VF1335 |
T2SS |
Effector delivery system |
VFC0086 |
Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB |
(gspK) general secretion pathway protein K [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636905.1_16 |
96.916 |
0.0 |
fimV |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(fimV) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636905.1_20 |
98.634 |
0.0 |
lpsB |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpsB) glycosyltransferase family 4 protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636905.1_21 |
94.855 |
0.0 |
lpxL |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636905.1_74 |
66.667 |
2.43E-84 |
clpP |
VF0074 |
ClpP |
Stress survival |
VFC0282 |
21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] |
Listeria monocytogenes |
| GL636905.1_101 |
99.624 |
0.0 |
pilF |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilF) type IV pilus biogenesis/stability protein PilW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_9 |
100.0 |
0.0 |
tagX |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tagX) type VI-associated gene X, peptidoglycan hydrolase [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_12 |
98.876 |
2.29E-60 |
tssL |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssL) type IVB secretion system protein TssL [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_13 |
100.0 |
8.63E-63 |
tssL |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssL) type IVB secretion system protein TssL [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_14 |
95.349 |
1.47E-23 |
tssK |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssK) type VI secretion system baseplate subunit TssK [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_15 |
98.611 |
1.34E-98 |
tssK |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssK) type VI secretion system baseplate subunit TssK [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_16 |
95.492 |
8.32E-172 |
tssK |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssK) type VI secretion system baseplate subunit TssK [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_17 |
99.725 |
0.0 |
tssA |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssA) type VI secretion system protein TssA [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_18 |
99.552 |
0.0 |
clpV/tssH |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(clpV/tssH) type VI secretion system ATPase TssH [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_22 |
99.686 |
0.0 |
tssM |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssM) type VI secretion system membrane subunit TssM [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_24 |
99.096 |
0.0 |
tssG |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssG) type VI secretion system baseplate subunit TssG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_25 |
96.689 |
0.0 |
tssF |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssF) type VI secretion system baseplate subunit TssF [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_26 |
100.0 |
2.59E-116 |
tssE |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssE) type VI secretion system baseplate subunit TssE [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_27 |
100.0 |
5.53E-126 |
hcp/tssD |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(hcp/tssD) type VI secretion system tube protein Hcp [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_28 |
100.0 |
0.0 |
tssC |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_29 |
100.0 |
4.65E-120 |
tssB |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(tssB) type VI secretion system contractile sheath small subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_39 |
85.196 |
0.0 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636908.1_40 |
94.969 |
6.32E-106 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636914.1_1 |
62.944 |
1.11E-87 |
sodB |
VF0169 |
SodB |
Stress survival |
VFC0282 |
|
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] |
Legionella pneumophila |
| GL636914.1_107 |
97.872 |
6.32E-95 |
adeH |
VF0504 |
AdeFGH efflux pump |
Biofilm |
VFC0271 |
Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii |
(adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636914.1_108 |
98.983 |
0.0 |
adeH |
VF0504 |
AdeFGH efflux pump |
Biofilm |
VFC0271 |
Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii |
(adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636914.1_109 |
99.905 |
0.0 |
adeG |
VF0504 |
AdeFGH efflux pump |
Biofilm |
VFC0271 |
Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii |
(adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636914.1_110 |
97.927 |
1.58E-138 |
adeF |
VF0504 |
AdeFGH efflux pump |
Biofilm |
VFC0271 |
Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii |
(adeF) membrane-fusion protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636914.1_111 |
100.0 |
1.48E-113 |
adeF |
VF0504 |
AdeFGH efflux pump |
Biofilm |
VFC0271 |
Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii |
(adeF) membrane-fusion protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636915.1_9 |
89.691 |
1.06E-62 |
pilE |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilE) type IV pilin protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636915.1_11 |
96.25 |
5.46E-114 |
ACICU_RS16840 |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(ACICU_RS16840) prepilin-type N-terminal cleavage/methylation domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636915.1_12 |
97.664 |
0.0 |
pilY1 |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilY1) VWA domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636915.1_13 |
98.776 |
4.97E-180 |
pilX |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilX) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636915.1_14 |
98.864 |
0.0 |
pilW |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilW) PilW family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636915.1_15 |
100.0 |
3.74E-138 |
pilV |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilV) type IV pilus modification protein PilV [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636915.1_16 |
99.363 |
1.07E-110 |
fimU |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(fimU) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636917.1_4 |
65.185 |
8.02E-55 |
katB |
VF0168 |
KatAB |
Stress survival |
VFC0282 |
|
(katB) catalase-peroxidase KatB [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] |
Legionella pneumophila |
| GL636919.1_29 |
100.0 |
0.0 |
lpxC |
VF0466 |
LPS |
Immune modulation |
VFC0258 |
|
(lpxC) UDP-3-O-acyl-N-acetylglucosamine deacetylase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_8 |
98.601 |
0.0 |
bauF |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(bauF) siderophore-interacting protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_10 |
95.504 |
0.0 |
basA |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basA) acinetobactin biosynthesis protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_11 |
97.959 |
0.0 |
basB |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basB) non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_12 |
94.737 |
0.0 |
basB |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basB) non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_13 |
98.333 |
0.0 |
bauD |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(bauD) ferric siderophore ABC transporter, permease protein BauD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_14 |
98.73 |
0.0 |
bauC |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(bauC) ferric siderophore ABC transporter, permease protein BauC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_15 |
99.219 |
0.0 |
bauE |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(bauE) ferric siderophore ABC transporter, ATP-binding protein BauE [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_16 |
98.758 |
0.0 |
bauB |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(bauB) ferric siderophore ABC transporter, periplasmic siderophore-binding protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_17 |
68.594 |
0.0 |
bauA |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(bauA) TonB-dependent siderophore receptor BauA [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_18 |
99.541 |
0.0 |
basC |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basC) acinetobactin biosynthesis protein BasC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_19 |
94.908 |
0.0 |
basD |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basD) acinetobactin biosynthesis protein BasD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_20 |
90.769 |
1.76E-38 |
entE |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(entE) non-ribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_21 |
98.901 |
1.77E-58 |
entE |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(entE) non-ribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_22 |
98.328 |
0.0 |
entE |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(entE) non-ribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_23 |
97.692 |
1.48E-93 |
basF |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basF) aryl carrier protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_24 |
100.0 |
1.69E-110 |
basF |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basF) aryl carrier protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636921.1_25 |
100.0 |
3.2E-21 |
basG |
VF0467 |
Acinetobactin |
Nutritional/Metabolic factor |
VFC0272 |
|
(basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636922.1_51 |
96.243 |
0.0 |
pilJ |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilJ) methyl-accepting chemotaxis protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636922.1_52 |
99.438 |
3.64E-134 |
pilI |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilI) chemotaxis protein CheW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636922.1_53 |
100.0 |
1.26E-86 |
pilH |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilH) response regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636922.1_54 |
100.0 |
9.66E-94 |
pilG |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilG) twitching motility response regulator PilG [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636922.1_82 |
93.966 |
0.0 |
ompA |
VF0464 |
OmpA |
Immune modulation |
VFC0258 |
|
(ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636922.1_83 |
98.83 |
6.65E-126 |
fimT |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(fimT) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636922.1_94 |
87.117 |
6.2E-97 |
vgrG/tssI |
VF1337 |
T6SS |
Effector delivery system |
VFC0086 |
|
(vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636927.1_77 |
100.0 |
4.02E-76 |
csuE |
VF0461 |
Csu fimbriae |
Biofilm |
VFC0271 |
Chaperone-usher pathway assembled fimbriae |
(csuE) Csu pilus tip adhesin CsuE [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636927.1_78 |
96.774 |
8.73E-155 |
csuE |
VF0461 |
Csu fimbriae |
Biofilm |
VFC0271 |
Chaperone-usher pathway assembled fimbriae |
(csuE) Csu pilus tip adhesin CsuE [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636927.1_79 |
99.399 |
0.0 |
csuD |
VF0461 |
Csu fimbriae |
Biofilm |
VFC0271 |
Chaperone-usher pathway assembled fimbriae |
(csuD) Csu pilus usher protein CsuD [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636927.1_80 |
99.639 |
0.0 |
csuC |
VF0461 |
Csu fimbriae |
Biofilm |
VFC0271 |
Chaperone-usher pathway assembled fimbriae |
(csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636927.1_81 |
97.093 |
6.31E-124 |
csuB |
VF0461 |
Csu fimbriae |
Biofilm |
VFC0271 |
Chaperone-usher pathway assembled fimbriae |
(csuB) Csu pilus subunit CsuB [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636927.1_83 |
99.438 |
1.5E-128 |
csuA/B |
VF0461 |
Csu fimbriae |
Biofilm |
VFC0271 |
Chaperone-usher pathway assembled fimbriae |
(csuA/B) Csu pilus major pilin subunit CsuA/B [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636928.1_6 |
100.0 |
0.0 |
pilQ |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilQ) type IV pilus secretin PilQ [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636928.1_7 |
100.0 |
1.17E-46 |
pilP |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilP) pilus assembly protein PilP [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636928.1_9 |
99.187 |
0.0 |
pilO |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilO) type 4a pilus biogenesis protein PilO [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636928.1_10 |
100.0 |
1.36E-161 |
pilN |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilN) PilN domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636928.1_11 |
94.602 |
0.0 |
pilM |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilM) pilus assembly protein PilM [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636929.1_31 |
99.433 |
0.0 |
pilU |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilU) PilT/PilU family type 4a pilus ATPase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |
| GL636929.1_32 |
100.0 |
0.0 |
pilT |
VF1334 |
TFP |
Adherence |
VFC0001 |
|
(pilT) type IV pilus twitching motility protein PilT [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] |
Acinetobacter baumannii |