| AFHB01000047.1_1 |
81.6 |
1.37E-75 |
tufA |
VF0460 |
EF-Tu |
Adherence |
VFC0001 |
|
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| AFHB01000045.1_31 |
69.052 |
0.0 |
cheD |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(cheD) methyl-accepting chemotaxis protein CheD [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000043.1_19 |
98.333 |
0.0 |
fimH |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimH) FimH protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_20 |
98.204 |
2.66E-119 |
fimG |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimG) FimG protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_21 |
98.295 |
5.3E-128 |
fimF |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimF) FimF protein precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_22 |
99.482 |
0.0 |
fimD |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_24 |
96.0 |
1.07E-138 |
fimD |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimD) Outer membrane usher protein fimD precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_25 |
98.755 |
3.5E-179 |
fimC |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimC) Chaperone protein fimC precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_26 |
96.97 |
4.73E-121 |
fimI |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimI) Fimbrin-like protein fimI precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_27 |
90.11 |
2.52E-103 |
fimA |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimA) Type-1 fimbrial protein, A chain precursor [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000043.1_28 |
100.0 |
7.59E-149 |
fimE |
VF0221 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Mannose-sensitive (MSHA) fimbriae, the ability to hemagglutinate erythrocytes was blocked by the presence of mannose; the genes responsible for type I fimbriae are found in almost all subgroups of E.coli, not just in UPEC strains, but the fimbriae function as a virulence factor in the pathogenesis of E.coli UTI; Expression of type I fimbriae undergoes phase variation controlled at the transcriptional level by invertible element. The sigma70 promoter for FimA is located within this 314bp invertible DNA element flanked on both ends by inverted DNA repeats of 9bp in length. Leucine-responsive protein (LRP), integration host factor (IHF), and the histone-like protein (H-NS) affect the switching of the invertible element by binding to DNA sequences around and within the invertible element region, thus assisting or blocking the switching actions of the FimB and FimE recombinases |
(fimE) Type 1 fimbriae Regulatory protein fimE [Type 1 fimbriae (VF0221) - Adherence (VFC0001)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000042.1_29 |
63.964 |
5.49E-101 |
rpe |
VF0543 |
Capsule |
Immune modulation |
VFC0258 |
Group 4 capsule; high molecular weight (HMW) O-antigen capsule |
(rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| AFHB01000042.1_59 |
66.832 |
1.28E-99 |
vfr |
VF0082 |
Type IV pili |
Adherence |
VFC0001 |
PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili |
(vfr) cAMP-regulatory protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] |
Pseudomonas aeruginosa |
| AFHB01000042.1_78 |
80.153 |
0.0 |
tufA |
VF0460 |
EF-Tu |
Adherence |
VFC0001 |
|
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| AFHB01000041.1_2 |
99.479 |
2.41E-128 |
sat |
VF0231 |
Sat |
Effector delivery system |
VFC0086 |
Belongs to SPATE (serine protease autotransporters to Enterobacteriaceae) proteins (eight known SPATE proteins: Sat of UPEC, Pet of EAEC, EspC of EPEC, Pic of EAEC and Shigella, SigA of Shigella, SepA of Shigella, Tsh of avian E. coli, and EspP of EHEC); reside within PAI II of E. coli CFT073 |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000041.1_3 |
100.0 |
0.0 |
iutA |
VF0123 |
Aerobactin |
Nutritional/Metabolic factor |
VFC0272 |
A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae |
(iutA) aerobactin receptor IutA [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000041.1_4 |
99.775 |
0.0 |
iucD |
VF0123 |
Aerobactin |
Nutritional/Metabolic factor |
VFC0272 |
A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae |
(iucD) aerobactin synthesis protein IucC, lysine 6-monooxygenase [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000041.1_5 |
100.0 |
0.0 |
iucC |
VF0123 |
Aerobactin |
Nutritional/Metabolic factor |
VFC0272 |
A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae |
(iucC) aerobactin synthesis protein IucC [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000041.1_6 |
100.0 |
0.0 |
iucB |
VF0123 |
Aerobactin |
Nutritional/Metabolic factor |
VFC0272 |
A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae |
(iucB) aerobactin synthesis protein IucB [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000041.1_7 |
100.0 |
0.0 |
iucA |
VF0123 |
Aerobactin |
Nutritional/Metabolic factor |
VFC0272 |
A hydroxamate siderophore expressed in many strains of E. coli, Shigella flexneri and Klebsiella pneumoniae |
(iucA) aerobactin synthesis protein IucA [Aerobactin (VF0123) - Nutritional/Metabolic factor (VFC0272)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000041.1_64 |
63.506 |
4.74E-158 |
rfaF |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(rfaF) ADP-heptose-LPS heptosyltransferase II [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000041.1_65 |
78.571 |
0.0 |
rfaD |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(rfaD) ADP-L-glycero-D-mannoheptose-6-epimerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000041.1_129 |
69.64 |
0.0 |
acrB |
VF0568 |
AcrAB |
Antimicrobial activity/Competitive advantage |
VFC0325 |
|
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000041.1_130 |
73.379 |
9.01E-154 |
acrB |
VF0568 |
AcrAB |
Antimicrobial activity/Competitive advantage |
VFC0325 |
|
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000040.1_40 |
97.838 |
6.84E-121 |
sat |
VF0231 |
Sat |
Effector delivery system |
VFC0086 |
Belongs to SPATE (serine protease autotransporters to Enterobacteriaceae) proteins (eight known SPATE proteins: Sat of UPEC, Pet of EAEC, EspC of EPEC, Pic of EAEC and Shigella, SigA of Shigella, SepA of Shigella, Tsh of avian E. coli, and EspP of EHEC); reside within PAI II of E. coli CFT073 |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000040.1_41 |
98.742 |
0.0 |
sat |
VF0231 |
Sat |
Effector delivery system |
VFC0086 |
Belongs to SPATE (serine protease autotransporters to Enterobacteriaceae) proteins (eight known SPATE proteins: Sat of UPEC, Pet of EAEC, EspC of EPEC, Pic of EAEC and Shigella, SigA of Shigella, SepA of Shigella, Tsh of avian E. coli, and EspP of EHEC); reside within PAI II of E. coli CFT073 |
(sat) Aecreted auto transpoter toxin [Sat (VF0231) - Effector delivery system (VFC0086)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000039.1_29 |
67.01 |
7.32E-144 |
wbtL |
VF0542 |
LPS |
Immune modulation |
VFC0258 |
The structure of Francisella spp. lipid A is unique in that it is modified by various carbohydrates that greatly reduce TLR4 activation and allow for immune evasion |
(wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| AFHB01000039.1_30 |
66.369 |
2.5E-171 |
rffG |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(rffG) dTDP-glucose 46-dehydratase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000037.1_1 |
85.714 |
5.5E-73 |
tufA |
VF0460 |
EF-Tu |
Adherence |
VFC0001 |
|
(tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| AFHB01000036.1_21 |
98.614 |
0.0 |
ibeC |
VF0237 |
Ibes |
Invasion |
VFC0083 |
IbeA is unique to E. coli K1. The ibeB and ibeC are found to have K12 homologues p77211 and yijP respectively. |
(ibeC) phosphoethanolamine transferase CptA [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88] |
Escherichia coli (NMEC) |
| AFHB01000034.1_1 |
87.037 |
4.91E-170 |
espX4 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000034.1_44 |
92.791 |
0.0 |
espX5 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espX5) Type III secretion system effector EspX5 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000034.1_64 |
86.197 |
0.0 |
pmrB |
VF1355 |
PmrAB |
Regulation |
VFC0301 |
|
(pmrB) sensory kinase PmrB [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000034.1_65 |
90.991 |
2.75E-150 |
pmrA |
VF1355 |
PmrAB |
Regulation |
VFC0301 |
|
(pmrA) response regulator PmrA [PmrAB (VF1355) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000034.1_94 |
92.0 |
8.27E-96 |
espL4 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espL4) Type III secretion system effector EspL4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000034.1_95 |
97.436 |
0.0 |
espL4 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espL4) Type III secretion system effector EspL4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000034.1_96 |
94.845 |
6.91E-126 |
espL4 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espL4) Type III secretion system effector EspL4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000034.1_97 |
96.61 |
3.03E-78 |
espL4 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espL4) Type III secretion system effector EspL4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000034.1_100 |
62.061 |
0.0 |
icl |
VF0253 |
Isocitrate lyase |
Others |
VFC0346 |
|
(icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv] |
Mycobacterium tuberculosis |
| AFHB01000033.1_21 |
78.689 |
3.42E-26 |
espX4 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000033.1_22 |
83.459 |
1.23E-75 |
espX4 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espX4) Type III secretion system effector EspX4 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000030.1_8 |
61.29 |
3.98E-39 |
STM0271 |
VF0974 |
SCI (Salmonella centrisome island)/SPI-6 T6SS |
Effector delivery system |
VFC0086 |
"The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1, |
|
|
| AFHB01000030.1_10 |
70.0 |
5.09E-110 |
STM0270 |
VF0974 |
SCI (Salmonella centrisome island)/SPI-6 T6SS |
Effector delivery system |
VFC0086 |
"The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1, |
|
|
| AFHB01000030.1_11 |
78.049 |
2.14E-92 |
STM0269 |
VF0974 |
SCI (Salmonella centrisome island)/SPI-6 T6SS |
Effector delivery system |
VFC0086 |
"The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1, |
|
|
| AFHB01000030.1_12 |
91.547 |
0.0 |
STM0268 |
VF0974 |
SCI (Salmonella centrisome island)/SPI-6 T6SS |
Effector delivery system |
VFC0086 |
"The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1, |
|
|
| AFHB01000030.1_13 |
79.208 |
2.38E-56 |
STM0267 |
VF0974 |
SCI (Salmonella centrisome island)/SPI-6 T6SS |
Effector delivery system |
VFC0086 |
"The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1, |
|
|
| AFHB01000030.1_14 |
71.795 |
4.07E-168 |
STM0266 |
VF0974 |
SCI (Salmonella centrisome island)/SPI-6 T6SS |
Effector delivery system |
VFC0086 |
"The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1, |
|
|
| AFHB01000029.1_281 |
70.815 |
0.0 |
rfaE |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(rfaE) ADP-heptose synthase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000029.1_331 |
99.724 |
0.0 |
cfaD/cfaE |
VF0213 |
Adhesive fimbriae |
Adherence |
VFC0001 |
Adherence is mediated by proteinaceous surface structures that are referred to as colonization factors (CFs), colonization factor antigens (CFAs), coli surface antigens (CSAs), or putative colonization factors (PCFs); ETEC strains are host-specific. The CFs confer host specificity on the strain. In human-specific ETEC strains, 21 different CFs have been identified. Approximately 75% of human ETEC express either CFA/I, CFA/II or CFA/IV. Animal-specific ETEC strains produce a variety of CFs that are distinct from those produced by human-specific isolates, such as K88 and K99; ETEC strains typically possess multiple plasmids with a wide range of molecular masses. The genes encoding CFs generally are found on a plasmid that also encodes ST and/or LT |
(cfaD/cfaE) minor pilin and initiator [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A] |
Escherichia coli (ETEC) |
| AFHB01000029.1_332 |
99.142 |
0.0 |
cfaC |
VF0213 |
Adhesive fimbriae |
Adherence |
VFC0001 |
Adherence is mediated by proteinaceous surface structures that are referred to as colonization factors (CFs), colonization factor antigens (CFAs), coli surface antigens (CSAs), or putative colonization factors (PCFs); ETEC strains are host-specific. The CFs confer host specificity on the strain. In human-specific ETEC strains, 21 different CFs have been identified. Approximately 75% of human ETEC express either CFA/I, CFA/II or CFA/IV. Animal-specific ETEC strains produce a variety of CFs that are distinct from those produced by human-specific isolates, such as K88 and K99; ETEC strains typically possess multiple plasmids with a wide range of molecular masses. The genes encoding CFs generally are found on a plasmid that also encodes ST and/or LT |
(cfaC) colonisation factor antigen c, usher [Adhesive fimbriae (VF0213) - Adherence (VFC0001)] [Escherichia coli E24377A] |
Escherichia coli (ETEC) |
| AFHB01000028.1_68 |
73.099 |
6.29E-96 |
luxS |
VF0406 |
AI-2 |
Biofilm |
VFC0271 |
AI-2 is produced and detected by a wide variety of bacteria and is presumed to facilitate interspecies communications. |
(luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961] |
Vibrio cholerae |
| AFHB01000028.1_72 |
76.667 |
1.4E-30 |
csrA |
VF0261 |
CsrA |
Regulation |
VFC0301 |
Belongs to a highly conserved family of global regulators that typically control stationary phase traits post-transcriptionally |
(csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] |
Legionella pneumophila |
| AFHB01000028.1_121 |
98.496 |
8.51E-89 |
rpoS |
VF0112 |
RpoS |
Regulation |
VFC0301 |
|
(rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000027.1_29 |
65.969 |
5.37E-91 |
algU |
VF0091 |
Alginate |
Biofilm |
VFC0271 |
Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC |
(algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] |
Pseudomonas aeruginosa |
| AFHB01000026.1_2 |
98.675 |
5.08E-104 |
ipaH9.8 |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH9.8) type III secretion system effector ipaH9.8, E3 ubiquitin ligase [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000025.1_109 |
96.759 |
1.41E-152 |
rcsB |
VF0571 |
RcsAB |
Regulation |
VFC0301 |
|
(rcsB) transcriptional regulator RcsB [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000025.1_342 |
64.637 |
0.0 |
acrB |
VF0568 |
AcrAB |
Antimicrobial activity/Competitive advantage |
VFC0325 |
|
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000024.1_23 |
97.231 |
0.0 |
ipaH0722 |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH0722) type III secretion system effector IpaH0722, E3 ubiquitin ligase [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000023.1_35 |
85.714 |
9.77E-52 |
ugd |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(ugd) UDP-glucose 6-dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_36 |
80.836 |
1.7E-176 |
ugd |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(ugd) UDP-glucose 6-dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_37 |
94.872 |
0.0 |
gndA |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(gndA) NADP-dependent phosphogluconate dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_49 |
64.483 |
1.17E-142 |
wbtL |
VF0542 |
LPS |
Immune modulation |
VFC0258 |
The structure of Francisella spp. lipid A is unique in that it is modified by various carbohydrates that greatly reduce TLR4 activation and allow for immune evasion |
(wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] |
Francisella tularensis |
| AFHB01000023.1_53 |
89.189 |
0.0 |
galF |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(galF) GalU regulator GalF [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_58 |
83.333 |
7.36E-55 |
wcaJ |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(wcaJ) undecaprenyl-phosphate glucose phosphotransferase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_59 |
60.106 |
1.63E-150 |
wcaJ |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(wcaJ) undecaprenyl-phosphate glucose phosphotransferase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_60 |
75.604 |
0.0 |
rfbK1 |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(rfbK1) O9 family phosphomannomutase RfbK1 [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_61 |
61.441 |
0.0 |
KP1_RS17280 |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(KP1_RS17280) mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_62 |
71.186 |
2.43E-56 |
KP1_RS17295 |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(KP1_RS17295) glycosyltransferase WbuB [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_65 |
77.987 |
0.0 |
KP1_RS17305 |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(KP1_RS17305) GDP-L-fucose synthase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_66 |
88.919 |
0.0 |
gmd |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(gmd) GDP-mannose 4,6-dehydratase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000023.1_76 |
64.644 |
0.0 |
KP1_RS17340 |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(KP1_RS17340) polysaccharide export protein [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000022.1_4 |
99.219 |
5.68E-87 |
ipaH |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH) invasion plasmid antigen IpaH [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000022.1_5 |
99.338 |
4.48E-106 |
ipaH |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH) invasion plasmid antigen IpaH [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000021.1_47 |
81.004 |
0.0 |
flhA |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flhA) flagellar biosynthesis protein FlhA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_48 |
94.301 |
5.13E-116 |
flhA |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flhA) flagellar biosynthesis protein FlhA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_49 |
64.305 |
3.52E-169 |
flhB |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flhB) flagellar biosynthetic protein FlhB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_55 |
76.699 |
2.62E-106 |
cheZ |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(cheZ) chemotaxis regulator CheZ [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_56 |
91.473 |
1.1E-84 |
cheY |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(cheY) chemotaxis regulatory protein CheY [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_57 |
86.246 |
0.0 |
cheB |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(cheB) chemotaxis-specific methylesterase CheB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_58 |
72.101 |
3.95E-145 |
cheR |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(cheR) chemotaxis methyltransferase CheR [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_61 |
85.093 |
3.74E-98 |
cheW |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(cheW) purine-binding chemotaxis protein CheW [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_62 |
73.225 |
0.0 |
cheA |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(cheA) chemotaxis protein CheA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_63 |
68.671 |
2.92E-151 |
motB |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(motB) flagellar motor protein MotB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_64 |
80.678 |
1.72E-179 |
motA |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(motA) flagellar motor protein MotA [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_65 |
82.902 |
5.06E-117 |
flhC |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flhC) flagellar biosynthesis transcription activator FlhC [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_66 |
66.667 |
4.12E-21 |
flhD |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flhD) flagellar transcriptional activator FlhD [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_82 |
60.417 |
2.82E-15 |
letA |
VF0262 |
LetA/S |
Regulation |
VFC0301 |
|
(letA) UvrY/SirA/GacA family response regulator transcription factor [LetA/S (VF0262) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] |
Legionella pneumophila |
| AFHB01000021.1_91 |
78.481 |
1.93E-86 |
fliA |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliA) flagellar biosynthesis sigma factor [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_92 |
95.833 |
1.15E-45 |
fliA |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliA) flagellar biosynthesis sigma factor [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_110 |
75.403 |
5.23E-129 |
fliF |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliF) flagellar M-ring protein FliF [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_112 |
83.283 |
0.0 |
fliG |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliG) flagellar motor switch protein G [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_114 |
83.48 |
0.0 |
fliI |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliI) flagellum-specific ATP synthase FliI [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_115 |
63.636 |
1.31E-43 |
fliJ |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliJ) flagellar protein FliJ [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_118 |
84.084 |
0.0 |
fliM |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliM) flagellar motor switch protein FliM [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_119 |
74.638 |
2.28E-69 |
fliN |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliN) flagellar motor switch protein FliN [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_122 |
86.022 |
6.58E-116 |
fliP |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliP) flagellar biosynthetic protein FliP [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_123 |
77.528 |
1.94E-37 |
fliQ |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliQ) flagellar biosynthetic protein FliQ [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_124 |
68.217 |
2.46E-106 |
fliR |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(fliR) flagellar biosynthetic protein FliR [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000021.1_125 |
67.633 |
2.11E-102 |
rcsA |
VF0571 |
RcsAB |
Regulation |
VFC0301 |
|
(rcsA) transcriptional activator for ctr capsule biosynthesis [RcsAB (VF0571) - Regulation (VFC0301)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000021.1_154 |
74.081 |
0.0 |
ipaH |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH) invasion plasmid antigen IpaH [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000020.1_53 |
99.497 |
2.67E-143 |
ipaH |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH) invasion plasmid antigen IpaH [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000019.1_6 |
67.539 |
7.96E-100 |
sodB |
VF0169 |
SodB |
Stress survival |
VFC0282 |
|
(sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] |
Legionella pneumophila |
| AFHB01000016.1_60 |
97.203 |
6.63E-97 |
espL1 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espL1) Type III secretion system effector espL1 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000016.1_61 |
92.623 |
1.66E-74 |
espL1 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espL1) Type III secretion system effector espL1 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000016.1_150 |
62.162 |
1.93E-140 |
narH |
VF0302 |
Nitrate reductase |
Nutritional/Metabolic factor |
VFC0272 |
NarX function as a respiratory fused nitrate reductase (three different domains present in this protein encode the difference subunits of nitrate reductase: the N-terminal domain showing similarity to narG, the central domain showing homology with narJ and the C-terminus showing homology to narI); NarGHJI is a membrane-bound nitrate reductase complex; NarK2, a putative nitrite-extrusion protein |
(narH) nitrate reductase subunit beta [Nitrate reductase (VF0302) - Nutritional/Metabolic factor (VFC0272)] [Mycobacterium tuberculosis H37Rv] |
Mycobacterium tuberculosis |
| AFHB01000016.1_155 |
90.789 |
9.01E-46 |
espR1 |
VF1110 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(espR1) Type III secretion system effector espR1 [TTSS secreted effectors (VF1110) - Effector delivery system (VFC0086)] [Escherichia coli O157:H7 str. EDL933] |
Escherichia coli (EHEC) |
| AFHB01000013.1_3 |
77.459 |
7.98E-140 |
flmH |
VF0473 |
Polar flagella |
Motility |
VFC0204 |
Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments |
(flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] |
Aeromonas hydrophila |
| AFHB01000013.1_4 |
61.538 |
1.93E-27 |
acpXL |
VF0367 |
LPS |
Immune modulation |
VFC0258 |
Brucella possesses a non-classical LPS as compared with the so-called classical LPS from enterobacteria such as Escherichia coli. B. abortus lipid A possesses a diaminoglucose backbone (rather than glucosamine), and acyl groups are longer (C28 rather than C12 and C16) and are only linked to the core by amide bounds (rather than ester and amide bonds).; In contrast to enterobacterial LPSs, Brucella LPS is several-hundred-times less active and toxic than E. coli LPS.; this is an evolutionary adaptation to an intracellular lifestyle, low endotoxic activity is shared by other intracellular pathogens such as Bartonella and Legionella. |
(acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M] |
Brucella melitensis |
| AFHB01000013.1_136 |
81.625 |
1.99E-178 |
kdsA |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000013.1_156 |
73.958 |
2.16E-159 |
galU |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(galU) glucosephosphate uridylyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000012.1_27 |
62.626 |
1.86E-34 |
flgM |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgM) negative regulator of flagellin synthesis [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_29 |
71.533 |
1.67E-73 |
flgB |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgB) flagellar basal-body rod protein FlgB [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_31 |
90.476 |
1.97E-22 |
flgC |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgC) flagellar basal-body rod protein FlgC [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_32 |
75.248 |
1.51E-104 |
flgD |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgD) flagellar basal-body rod modification protein FlgD [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_33 |
61.337 |
5.14E-174 |
flgE |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgE) flagellar hook protein FlgE [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_34 |
63.291 |
1.24E-68 |
flgF |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgF) flagellar basal-body rod protein FlgF [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_35 |
86.538 |
4.81E-169 |
flgG |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgG) flagellar basal-body rod protein FlgG [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_36 |
81.193 |
3.69E-122 |
flgH |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgH) flagellar L-ring protein precursor FlgH [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_37 |
78.356 |
0.0 |
flgI |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgI) flagellar P-ring protein precursor FlgI [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_39 |
63.436 |
1.02E-93 |
flgK |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgK) flagellar hook-associated protein 1 FlgK [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000012.1_41 |
67.407 |
5.1E-63 |
flgL |
VF0394 |
Flagella |
Motility |
VFC0204 |
|
(flgL) flagellar hook-associated protein 3 FlgL [Flagella (VF0394) - Motility (VFC0204)] [Yersinia enterocolitica subsp. enterocolitica 8081] |
Yersinia enterocolitica |
| AFHB01000011.1_78 |
94.857 |
0.0 |
ompA |
VF0236 |
OmpA |
Invasion |
VFC0083 |
Major outer membrane protein in E. coli, homologous to Neisseria Opa proteins which have been shown to be involved in invasion of eukaryotic cells |
(ompA) outer membrane protein A [OmpA (VF0236) - Invasion (VFC0083)] [Escherichia coli O18:K1:H7 str. RS218] |
Escherichia coli (NMEC) |
| AFHB01000011.1_107 |
72.414 |
0.0 |
KP1_RS17340 |
VF0560 |
Capsule |
Immune modulation |
VFC0258 |
The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. |
(KP1_RS17340) polysaccharide export protein [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000011.1_156 |
100.0 |
3.62E-83 |
cgsG |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(cgsG) curli production assembly/transport protein CsgG [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000011.1_157 |
78.182 |
1.21E-56 |
cgsG |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(cgsG) curli production assembly/transport protein CsgG [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000011.1_158 |
99.275 |
1.6E-99 |
cgsF |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(cgsF) curli production assembly/transport protein CsgF [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000011.1_159 |
98.45 |
8.36E-93 |
cgsE |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(cgsE) curli production assembly/transport protein CsgE [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000011.1_160 |
100.0 |
9.54E-163 |
cgsD |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(cgsD) transcriptional regulator CsgD [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000011.1_161 |
99.338 |
5.9E-106 |
csgB |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(csgB) curlin minor subunit CsgB [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000011.1_164 |
97.391 |
1.05E-76 |
csgA |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(csgA) curlin major subunit CsgA [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000011.1_165 |
97.273 |
8.44E-75 |
csgC |
VF1138 |
Curli fibers |
Adherence |
VFC0001 |
Many commensal E. coli strains and the commonly studied lab strains express curli at temperatures of <30°C. In contrast, pathogenic E. coli strains like UPECs, EAECs including the 2012 German outbreak strain and S. Typhimurium, have been shown to express curli at 37°C |
(csgC) curli assembly protein CsgC [Curli fibers (VF1138) - Adherence (VFC0001)] [Escherichia coli O25b:H4-ST131] |
Escherichia coli (UPEC) |
| AFHB01000010.1_31 |
66.955 |
0.0 |
msbA |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000010.1_35 |
69.076 |
4.95E-125 |
nueA |
VF0473 |
Polar flagella |
Motility |
VFC0204 |
Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments |
(nueA) NeuA protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] |
Aeromonas hydrophila |
| AFHB01000009.1_3 |
98.227 |
0.0 |
ipaH |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH) invasion plasmid antigen IpaH [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000007.1_4 |
100.0 |
0.0 |
ipaH0722 |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH0722) type III secretion system effector IpaH0722, E3 ubiquitin ligase [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000007.1_146 |
99.825 |
0.0 |
ipaH |
VF0978 |
TTSS secreted effectors |
Effector delivery system |
VFC0086 |
|
(ipaH) invasion plasmid antigen IpaH [TTSS secreted effectors (VF0978) - Effector delivery system (VFC0086)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000006.1_5 |
94.416 |
5.51E-140 |
entD |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entD) phosphopantetheinyl transferase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_6 |
99.464 |
0.0 |
fepA |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fepA) ferrienterobactin outer membrane transporter [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_7 |
96.0 |
0.0 |
fes |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fes) enterobactin/ferric enterobactin esterase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_9 |
95.666 |
0.0 |
entF |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entF) enterobactin synthase multienzyme complex component, ATP-dependent [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_10 |
94.795 |
0.0 |
entF |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entF) enterobactin synthase multienzyme complex component, ATP-dependent [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_12 |
86.813 |
5.45E-54 |
fepE |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fepE) LPS O-antigen length regulator [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_13 |
94.69 |
6.26E-158 |
fepE |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fepE) LPS O-antigen length regulator [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_14 |
98.889 |
0.0 |
fepC |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_15 |
96.667 |
0.0 |
fepG |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fepG) iron-enterobactin ABC transporter permease [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_16 |
99.401 |
0.0 |
fepD |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fepD) ferrienterobactin ABC transporter permease [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_17 |
97.115 |
0.0 |
entS |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entS) enterobactin exporter, iron-regulated [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_18 |
99.371 |
0.0 |
fepB |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(fepB) ferrienterobactin ABC transporter periplasmic binding protein [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_19 |
100.0 |
5.36E-64 |
entC |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entC) isochorismate synthase 1 [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_20 |
98.182 |
0.0 |
entC |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entC) isochorismate synthase 1 [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_21 |
97.948 |
0.0 |
entE |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entE) 2,3-dihydroxybenzoate-AMP ligase component of enterobactin synthase multienzyme complex [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_22 |
99.649 |
0.0 |
entB |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entB) isochorismatase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_23 |
97.581 |
1.72E-180 |
entA |
VF0228 |
Enterobactin |
Nutritional/Metabolic factor |
VFC0272 |
An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three |
(entA) 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase EntA [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] |
Escherichia coli (UPEC) |
| AFHB01000006.1_137 |
99.315 |
1.76E-107 |
fur |
VF0113 |
Fur |
Regulation |
VFC0301 |
|
(fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000005.1_7 |
66.495 |
8.54E-98 |
clpP |
VF0074 |
ClpP |
Stress survival |
VFC0282 |
21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes |
(clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] |
Listeria monocytogenes |
| AFHB01000005.1_37 |
91.325 |
0.0 |
acrB |
VF0568 |
AcrAB |
Antimicrobial activity/Competitive advantage |
VFC0325 |
|
(acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000005.1_38 |
84.635 |
0.0 |
acrA |
VF0568 |
AcrAB |
Antimicrobial activity/Competitive advantage |
VFC0325 |
|
(acrA) acriflavine resistance protein A [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000005.1_74 |
73.267 |
1.7E-170 |
allS |
VF0572 |
Allantion utilization |
Nutritional/Metabolic factor |
VFC0272 |
An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. |
(allS) DNA-binding transcriptional activator AllS [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000005.1_75 |
74.375 |
1.46E-91 |
allA |
VF0572 |
Allantion utilization |
Nutritional/Metabolic factor |
VFC0272 |
An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. |
(allA) ureidoglycolate hydrolase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000005.1_76 |
85.821 |
8.99E-176 |
allR |
VF0572 |
Allantion utilization |
Nutritional/Metabolic factor |
VFC0272 |
An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. |
(allR) DNA-binding transcriptional repressor AllR [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000005.1_81 |
80.274 |
0.0 |
allC |
VF0572 |
Allantion utilization |
Nutritional/Metabolic factor |
VFC0272 |
An allantoin utilization operon has been associated with hypervirulent K. pneumoniae strains that cause pyogenic liver abscesses. |
(allC) allantoate amidohydrolase [Allantion utilization (VF0572) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] |
Klebsiella pneumoniae |
| AFHB01000005.1_92 |
64.865 |
4.65E-83 |
fimA |
VF0102 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Chaperone-usher assembly pathway |
(fimA) type-1 fimbrial protein subunit A [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000005.1_93 |
61.135 |
1.65E-103 |
fimC |
VF0102 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Chaperone-usher assembly pathway |
(fimC) chaperone protein FimC [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000005.1_96 |
76.056 |
1.3E-35 |
fimZ |
VF0102 |
Type 1 fimbriae |
Adherence |
VFC0001 |
Chaperone-usher assembly pathway |
(fimZ) DNA-binding response regulator [Type 1 fimbriae (VF0102) - Adherence (VFC0001)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000005.1_107 |
97.99 |
0.0 |
ibeB |
VF0237 |
Ibes |
Invasion |
VFC0083 |
IbeA is unique to E. coli K1. The ibeB and ibeC are found to have K12 homologues p77211 and yijP respectively. |
(ibeB) Cu(+)/Ag(+) efflux RND transporter outer membrane channel CusC [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88] |
Escherichia coli (NMEC) |
| AFHB01000004.1_26 |
84.469 |
0.0 |
vgrG |
VF0974 |
SCI (Salmonella centrisome island)/SPI-6 T6SS |
Effector delivery system |
VFC0086 |
"The T6SS is widely distributed in all Salmonella species and subspecies.; Salmonella T6SSs are located on five different Salmonella pathogenicity island and phylogenetically belong to i1, |
|
|
| AFHB01000004.1_28 |
85.827 |
9.62E-55 |
tre<sup>Tu</sup> |
VF1195 |
SCI T6SS secreted effectors |
Effector delivery system |
VFC0086 |
|
(tre<up>Tu</up>) Rhs polymorphic toxin, ADP-ribosyltransferase, type VI ribosyltransferase effector targeting EF-Tu [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000004.1_29 |
68.735 |
0.0 |
tre<sup>Tu</sup> |
VF1195 |
SCI T6SS secreted effectors |
Effector delivery system |
VFC0086 |
|
(tre<up>Tu</up>) Rhs polymorphic toxin, ADP-ribosyltransferase, type VI ribosyltransferase effector targeting EF-Tu [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000004.1_30 |
78.498 |
1.02E-155 |
tre<sup>Tu</sup> |
VF1195 |
SCI T6SS secreted effectors |
Effector delivery system |
VFC0086 |
|
(tre<up>Tu</up>) Rhs polymorphic toxin, ADP-ribosyltransferase, type VI ribosyltransferase effector targeting EF-Tu [SCI T6SS secreted effectors (VF1195) - Effector delivery system (VFC0086)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] |
Salmonella enterica (serovar typhimurium) |
| AFHB01000004.1_35 |
74.479 |
8.28E-108 |
gmhA/lpcA |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(gmhA/lpcA) phosphoheptose isomerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000004.1_70 |
100.0 |
1.88E-84 |
gtrA |
VF0124 |
LPS |
Immune modulation |
VFC0258 |
Composed of the O-antigen, core polysaccharides and lipid A; the genes involved in the biosynthesis of the basic O-antigen are located in the rfb/rfc loci; O-antigen modification is associated with temperate bacteriophages. Four different serotype-converting phages have been found: SfII, Sf6, SfV and SfX, which are involved in conversion of a serotype Y stain to serotypes 2a, 3b, 5a and X, respectively |
(gtrA) bactoprenol-linked glucose translocase/flippase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000004.1_71 |
100.0 |
0.0 |
gtrB |
VF0124 |
LPS |
Immune modulation |
VFC0258 |
Composed of the O-antigen, core polysaccharides and lipid A; the genes involved in the biosynthesis of the basic O-antigen are located in the rfb/rfc loci; O-antigen modification is associated with temperate bacteriophages. Four different serotype-converting phages have been found: SfII, Sf6, SfV and SfX, which are involved in conversion of a serotype Y stain to serotypes 2a, 3b, 5a and X, respectively |
(gtrB) bactoprenol glucosyl transferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000004.1_72 |
98.847 |
0.0 |
gtr |
VF0124 |
LPS |
Immune modulation |
VFC0258 |
Composed of the O-antigen, core polysaccharides and lipid A; the genes involved in the biosynthesis of the basic O-antigen are located in the rfb/rfc loci; O-antigen modification is associated with temperate bacteriophages. Four different serotype-converting phages have been found: SfII, Sf6, SfV and SfX, which are involved in conversion of a serotype Y stain to serotypes 2a, 3b, 5a and X, respectively |
(gtr) glucosyl tranferase [LPS (VF0124) - Immune modulation (VFC0258)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000003.1_67 |
75.568 |
0.0 |
htpB |
VF0159 |
Hsp60 |
Adherence |
VFC0001 |
|
(htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] |
Legionella pneumophila |
| AFHB01000003.1_80 |
100.0 |
0.0 |
sigA |
VF0119 |
SigA |
Exoenzyme |
VFC0251 |
Belongs to the SPATEs (serine protease autotransporters of Enterobacteriaceae) subfamily, cytotoxic SPATE;carried on the she pathogenicity island of Shigella flexneri 2a |
(sigA) serine protease, autotransporter SigA [SigA (VF0119) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000003.1_86 |
100.0 |
0.0 |
pic |
VF0120 |
Pic |
Exoenzyme |
VFC0251 |
Produced by Shigella flexneri, EAEC and UPEC; belongs to the SPATEs (serine protease autotransporters of Enterobacteriaceae) subfamily, noncytotoxic (class 2) SPATE; the pic gene overlaps two other virulence genes, set1A and set1B |
(pic) serine protease, autotransporter Pic [Pic (VF0120) - Exoenzyme (VFC0251)] [Shigella flexneri 2a str. 301] |
Shigella flexneri |
| AFHB01000002.1_31 |
65.089 |
1.35E-160 |
lpxD |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(lpxD) UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000002.1_33 |
67.557 |
1.62E-132 |
lpxA |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(lpxA) UDP-N-acetylglucosamine acyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000002.1_34 |
63.281 |
6.64E-176 |
lpxB |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(lpxB) lipid-A-disaccharide synthase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |
| AFHB01000002.1_49 |
67.528 |
1.16E-127 |
IlpA |
VF0513 |
IlpA |
Adherence |
VFC0001 |
|
(IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016] |
Vibrio vulnificus |
| AFHB01000001.1_85 |
77.303 |
0.0 |
lpxC |
VF0044 |
LOS |
Immune modulation |
VFC0258 |
Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. |
(lpxC) UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] |
Haemophilus influenzae |