2. PATHOGENS
Basic Information
Accession number
GCA_000233495.1
Release date
2011-11-02
Organism
Pseudomonas aeruginosa
Species name
Pseudomonas aeruginosa
Assembly level
Scaffold
Assembly name
Pseudomonas_sp_2_1_26_V1
Assembly submitter
Broad Institute
Assembly Type
haploid
Genome size
6.4 Mb
GC percent
66.5
Contig count
295
Collection date
-
Sample location
-
Host
Homo sapiens
Isolation source
gastrointestinal tract
Isolate type
-
Strain
2_1_26
Isolate
-
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
JH376461.1_3 # 2262 # 3725 920.0 946.806 OpmD 99.59 ARO:3000809 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OpmD is the outer membrane channel protein of the efflux complex MexGHI-OpmD.
JH376461.1_4 # 3722 # 6811 1900.0 2057.72 MexI 99.9 ARO:3000808 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexI is the inner membrane transporter of the efflux complex MexGHI-OpmD.
JH376461.1_5 # 6824 # 7936 650.0 726.857 MexH 99.46 ARO:3000807 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexH is the membrane fusion protein of the efflux complex MexGHI-OpmD.
JH376461.1_6 # 7944 # 8390 260.0 290.041 MexG 99.32 ARO:3000806 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexG is a membrane protein required for MexGHI-OpmD efflux activity.
JH376461.1_75 # 88561 # 89769 500.0 754.592 bcr-1 99.75 ARO:3003801 protein homolog model bicyclomycin-like antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Transmembrane protein which expels bicyclomycin from the cell, leading to bicyclomycin resistance. Identified in Pseudomonas aeruginosa strains responsible for outbreaks in Brazil, often appearing with blaSPM-1, another bicyclomycin resistance gene.
JH376461.1_92 # 106474 # 107280 500.0 528.48 APH(3')-IIb 98.88 ARO:3002645 protein homolog model aminoglycoside antibiotic antibiotic inactivation APH(3') APH(3')-IIb is a chromosomal-encoded aminoglycoside phosphotransferase in P. aeruginosa.
JH376461.1_101 # 119636 # 120829 700.0 806.209 PDC-12 100.0 ARO:3006495 protein homolog model monobactam; carbapenem; cephalosporin antibiotic inactivation PDC beta-lactamase PDC-12 is a PDC beta-lactamase.
JH376461.1_393 # 434198 # 434536 200.0 223.787 YajC 100.0 ARO:3005040 protein homolog model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; oxazolidinone antibiotic; glycopeptide antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump YajC interacts with the AcrAB-TolC efflux pump in a way that in uncharacterized but is shown to grant increased fitness in the presence of linezolid, rifampicin, and vancomycin.
JH376461.1_548 # 599714 # 600352 400.0 426.402 MexL 99.53 ARO:3003710 protein homolog model macrolide antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexL is a specific repressor of mexJK transcription and autoregulates its own expression.
JH376461.1_549 # 600448 # 601551 690.0 721.079 MexJ 99.46 ARO:3003692 protein homolog model macrolide antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexJ is the membrane fusion protein of the MexJK multidrug efflux protein.
JH376461.1_550 # 601556 # 604633 1900.0 2061.57 MexK 99.9 ARO:3003693 protein homolog model macrolide antibiotic; tetracycline antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexK is the inner membrane resistance-nodulation-cell division (RND) transporter in the MexJK multidrug efflux protein.
JH376461.1_673 # 735061 # 736710 400.0 443.351 ArnT 43.75 ARO:3005053 protein homolog model peptide antibiotic antibiotic target alteration pmr phosphoethanolamine transferase ArnT is involved in Cell Wall Biosynthesis, specifically 4-amino-4-deoxy-L-arabinose (Ara4N). It confers resistance to peptide antibiotics.
JH376461.1_675 # 737591 # 739579 1200.0 1344.72 arnA 99.4 ARO:3002985 protein homolog model peptide antibiotic antibiotic target alteration pmr phosphoethanolamine transferase arnA modifies lipid A with 4-amino-4-deoxy-L-arabinose (Ara4N) which allows gram-negative bacteria to resist the antimicrobial activity of cationic antimicrobial peptides and antibiotics such as polymyxin. arnA is found in E. coli and P. aeruginosa.
JH376461.1_705 # 777929 # 779086 650.0 753.821 mexP 99.48 ARO:3003698 protein homolog model macrolide antibiotic; carbapenem; tetracycline antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexP is the membrane fusion protein of the MexPQ-OpmE multidrug efflux complex.
JH376461.1_706 # 779083 # 782244 1900.0 2078.91 mexQ 99.53 ARO:3003699 protein homolog model macrolide antibiotic; carbapenem; tetracycline antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexQ is the inner membrane transporter of the multidrug efflux pump MexPQ-OpmE.
JH376461.1_707 # 782241 # 783716 850.0 949.503 opmE 99.59 ARO:3003700 protein homolog model macrolide antibiotic; carbapenem; tetracycline antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump opmE is an outer membrane factor protein that is part of the multidrug efflux pump MexPQ-OpmE.
JH376461.1_1019 # 1114798 # 1115475 400.0 441.039 Pseudomonas aeruginosa CpxR 100.0 ARO:3004054 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump CpxR is directly involved in activation of expression of RND efflux pump MexAB-OprM in P. aeruginosa. CpxR is required to enhance mexAB-oprM expression and drug resistance, in the absence of repressor MexR.
JH376461.1_1140 # 1253193 # 1254488 800.0 869.381 cprS 99.3 ARO:3005064 protein homolog model peptide antibiotic antibiotic target alteration; antibiotic efflux pmr phosphoethanolamine transferase cprS is part of a two-component regulatory system that, with its counterpart cprR, induces the Arn operon in the presence of cationic peptides to confer resistance.
JH376461.1_1141 # 1254485 # 1255156 400.0 453.366 cprR 100.0 ARO:3005063 protein homolog model peptide antibiotic antibiotic target alteration; antibiotic efflux pmr phosphoethanolamine transferase cprR is one part of a two-component regulatory system. It with its counterpart cprS induce the Arn operon to confer resistance to peptide antibiotics.
JH376461.1_1791 # 1920513 # 1921793 800.0 846.269 MuxA 99.77 ARO:3004073 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MuxA is a membrane fusion protein component of the efflux pump system MuxABC-OpmB in Pseudomonas aeruginosa.
JH376461.1_1792 # 1921790 # 1924921 1900.0 2073.13 MuxB 99.9 ARO:3004074 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MuxB is one of the two necessary RND components in the Pseudomonas aeruginosa efflux pump system MuxABC-OpmB.
JH376461.1_1793 # 1924918 # 1928028 1900.0 2078.91 MuxC 100.0 ARO:3004075 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MuxC is one of the two necessary RND components of the MuxABC-OpmB efflux pumps system in Pseudomonas aeruginosa.
JH376461.1_1794 # 1928025 # 1929521 850.0 1003.05 OpmB 99.8 ARO:3004072 protein homolog model macrolide antibiotic; monobactam; tetracycline antibiotic; aminocoumarin antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OpmB is an outer membrane efflux protein in Pseudomonas aeruginosa that shows functional cooperation with MuxABC, to form the efflux pump system MuxABC-OpmB.
JH376461.1_1826 # 1961705 # 1963123 800.0 918.302 OprN 99.79 ARO:3000805 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OprN is the outer membrane channel component of the MexEF-OprN multidrug efflux complex.
JH376461.1_1827 # 1963120 # 1966308 2110.0 2147.09 MexF 100.0 ARO:3000804 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexF is the multidrug inner membrane transporter of the MexEF-OprN complex. mexF corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: mexF/mexB) and 4 loci in Pseudomonas aeruginosa LESB58 (gene name: mexD/mexB).
JH376461.1_1828 # 1966330 # 1967574 750.0 836.639 MexE 100.0 ARO:3000803 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexE is the membrane fusion protein of the MexEF-OprN multidrug efflux complex.
JH376462.1_87 # 96311 # 97744 900.0 938.332 basS 98.95 ARO:3003583 protein homolog model peptide antibiotic antibiotic target alteration; antibiotic efflux pmr phosphoethanolamine transferase Histidine protein kinase sensor Lipid A modification gene; part of a two-component system involved in polymyxin resistance that senses high extracellular Fe(2+).
JH376462.1_291 # 315647 # 317095 850.0 967.222 OpmH 100.0 ARO:3003682 protein homolog model disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OpmH is an outer membrane efflux protein required for triclosan-specific efflux pump function.
JH376462.1_309 # 337353 # 337685 170.0 206.838 Pseudomonas aeruginosa emrE 100.0 ARO:3004038 protein homolog model aminoglycoside antibiotic antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump EmrE is a small multidrug transporter that functions as a homodimer and that couples the efflux of small polyaromatic cations from the cell with the import of protons down an electrochemical gradient. Confers resistance to tetraphenylphosphonium, methyl viologen, gentamicin, kanamycin, and neomycin.
JH376463.1_110 # 123287 # 123994 400.0 469.159 ParR 99.15 ARO:3005068 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic efflux; reduced permeability to antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump; Outer Membrane Porin (Opr) ParR is a component of the two-component sensor ParRS. Alongside its counterpart ParS, it confers resistance to polycationic antibiotics through the regulation of efflux components and porins.
JH376463.1_111 # 123995 # 125281 800.0 857.055 ParS 99.53 ARO:3005067 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic efflux; reduced permeability to antibiotic resistance-nodulation-cell division (RND) antibiotic efflux pump; Outer Membrane Porin (Opr) ParS is the sensor component of the two-component ParRS system. Alongside its counterpart ParR, it confers resistance to polycationic antibiotics though regulation of efflux pumps and porins.
JH376463.1_487 # 517879 # 519036 650.0 734.947 mexM 98.7 ARO:3003704 protein homolog model phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump mexM is the membrane fusion protein of the MexMN-OprM multidrug efflux complex.
JH376464.1_124 # 131092 # 132195 650.0 715.687 TriA 98.37 ARO:3003679 protein homolog model disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump TriA is a membrane protein that is fused to TriB and both are required for the triclosan efflux pump function of TriABC-OpmH in P. aeruginosa.
JH376464.1_125 # 132192 # 133262 600.0 699.123 TriB 100.0 ARO:3003680 protein homolog model disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump TriB is a membrane protein that is fused to TriA and both are required for the triclosan efflux pump function of TriABC-OpmH in P. aeruginosa.
JH376464.1_126 # 133259 # 136306 1900.0 2047.32 TriC 99.7 ARO:3003681 protein homolog model disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump TriC is a resistance nodulation cell division (RND) transporter that is a part of TriABC-OpmH, a triclosan-specific efflux protein.
JH376464.1_391 # 414284 # 415435 650.0 768.074 MexA 100.0 ARO:3000377 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexA is the membrane fusion protein of the MexAB-OprM multidrug efflux complex.
JH376464.1_392 # 415451 # 418591 1950.0 2120.12 MexB 99.9 ARO:3000378 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexB is the inner membrane multidrug exporter of the efflux complex MexAB-OprM.
JH376464.1_393 # 418593 # 420050 850.0 963.37 OprM 100.0 ARO:3000379 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OprM is an outer membrane factor protein found in Pseudomonas aeruginosa and Burkholderia vietnamiensis. It is part of the MexAB-OprM, MexVW-OprM, MexXY-OprM and the AmrAB-OprM complex.
JH376465.1_40 # 52827 # 53465 400.0 438.728 Pseudomonas aeruginosa catB7 98.58 ARO:3002679 protein homolog model phenicol antibiotic antibiotic inactivation chloramphenicol acetyltransferase (CAT) catB7 is a chromosome-encoded variant of the cat gene found in Pseudomonas aeruginosa.
JH376465.1_85 # 90203 # 91024 50.0 149.828 vanW gene in vanG cluster 32.58 ARO:3002965 protein homolog model glycopeptide antibiotic antibiotic target alteration vanW; glycopeptide resistance gene cluster Also known as vanWG, is a vanW variant found in the vanG gene cluster.
JH376465.1_251 # 272857 # 273042 100.0 122.865 rsmA 100.0 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
JH376465.1_273 # 294202 # 295191 200.0 200.29 vanH gene in vanB cluster 40.91 ARO:3002943 protein homolog model glycopeptide antibiotic antibiotic target alteration vanH; glycopeptide resistance gene cluster Also known as vanHB, is a vanH variant in the vanB gene cluster.
JH376465.1_483 # 502803 # 503210 200.0 273.478 FosA 100.0 ARO:3000149 protein homolog model phosphonic acid antibiotic antibiotic inactivation fosfomycin thiol transferase An enzyme that confers resistance to fosfomycin in Serratia marcescens by breaking the epoxide ring of the molecule. It depends on the cofactors Manganese (II) and Potassium and uses Glutathione (GSH) as the nucleophilic molecule. In Pseudomonas aeruginosa, FosA catalyzes the conjugation of glutathione to carbon-1 of fosfomycin, rendering it ineffective as an antibacterial drug.
JH376466.1_115 # 128046 # 131183 1800.0 1922.52 mexY 93.69 ARO:3003033 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexY is the RND-type membrane protein of the efflux complex MexXY-OprM.
JH376466.1_369 # 409512 # 409982 200.0 314.694 Pseudomonas aeruginosa soxR 100.0 ARO:3004107 protein homolog model fluoroquinolone antibiotic; cephalosporin; glycylcycline; penam; tetracycline antibiotic; rifamycin antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic target alteration; antibiotic efflux ATP-binding cassette (ABC) antibiotic efflux pump; major facilitator superfamily (MFS) antibiotic efflux pump; resistance-nodulation-cell division (RND) antibiotic efflux pump SoxR is a redox-sensitive transcriptional activator that induces expression of a small regulon that includes the RND efflux pump-encoding operon mexGHI-opmD. SoxR was shown to be activated by pyocyanin.
JH376467.1_232 # 238407 # 241463 1900.0 2045.4 MexW 99.8 ARO:3003031 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexW is the RND-type membrane protein of the efflux complex MexVW-OprM.
JH376467.1_233 # 241514 # 242644 650.0 744.191 MexV 99.47 ARO:3003030 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexV is the membrane fusion protein of the MexVW-OprM multidrug efflux complex.
JH376468.1_148 # 162686 # 163474 500.0 536.569 OXA-905 100.0 ARO:3006093 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-905 is a OXA beta-lactamase.
JH376470.1_100 # 112912 # 113976 600.0 676.396 MexC 98.02 ARO:3000800 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexC is the membrane fusion protein of the MexCD-OprJ multidrug efflux complex.
JH376470.1_101 # 114004 # 117135 1800.0 1920.98 MexD 94.86 ARO:3000801 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexD is the multidrug inner membrane transporter of the MexCD-OprJ complex.
JH376470.1_102 # 117141 # 118580 850.0 932.554 OprJ 99.16 ARO:3000802 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump OprJ is the outer membrane channel component of the MexCD-OprJ multidrug efflux complex.
JH376461.1_506 # 553636 # 554277 400.0 425.246 nalC 99.06 ARO:3000818 protein overexpression model S209R, G71E macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump NalC is a repressor of PA3720-PA3719, which are positive regulators of MexAB-OprM. Thus, nalC mutants confer multidrug resistance.
JH376461.1_653 # 714471 # 715109 375.0 436.032 nalD 100.0 ARO:3000819 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump NalD is a repressor of MexAB-OprM. Mutations lead to multidrug resistance and MexAB-OprM overexpression.
JH376461.1_1829 # 1967805 # 1968719 500.0 534.258 MexT 99.63 ARO:3000814 protein overexpression model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexT is a LysR-type transcriptional activator that positively regulates the expression of MexEF-OprN, OprD, and MexS.
JH376461.1_1830 # 1968940 # 1969959 660.0 689.493 MexS 100.0 ARO:3000813 protein overexpression model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexS is a suppressor of MexT, which is an activator of the multidrug pump MexEF-OprN. Mutations in MexS lead to multidrug resistance.
JH376464.1_390 # 413566 # 414009 270.0 295.049 MexR 99.32 ARO:3000506 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; monobactam; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; peptide antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; sulfonamide antibiotic; phenicol antibiotic; penem antibiotic target alteration; antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexR is the repressor of the MexRAB-OprM operon. Mutant forms of mexR result in up-regulation of efflux pump system MexAB-OprM.
JH376466.1_117 # 132554 # 133186 390.0 423.705 MexZ 100.0 ARO:3003709 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; carbapenem; cephalosporin; cephamycin; penam; tetracycline antibiotic; phenicol antibiotic; disinfecting agents and antiseptics antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump MexZ is a transcriptional regulator that downregulates the mexXY multidrug transporter operon, which confers to aminoglycoside resistance on Pseudomonas aeruginosa.
JH376470.1_99 # 112089 # 112652 310.0 378.637 Type B NfxB 98.93 ARO:3004060 protein overexpression model macrolide antibiotic; fluoroquinolone antibiotic; aminoglycoside antibiotic; cephalosporin; penam; tetracycline antibiotic; aminocoumarin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump Type B NfxB mutants are more resistant to tetracycline and chloramphenicol, as well as ofloxacin, erythromycin, and the new zwitterionic cephems, than was PAO1, and they are four to eight times more susceptible to carbenicillin, sulbenicillin, imipenem, panipenem, biapenem, moxalactam, aztreonam, gentamicin, and kanamycin than PAO1. The mutation at the 46th amino acid position is sufficient for overproduction of OprJ and the multidrug resistance. nfxB corresponds to 2 loci in Pseudomonas aeruginosa PAO1 (gene name: esrC/nfxB) and 2 loci in Pseudomonas aeruginosa LESB58 (gene name: nfxB).
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
JH376461.1_1 100.0 3.57E-122 phzA1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzA1) phenazine biosynthesis protein PhzA [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_2 99.701 0.0 phzM VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzM) phenazine-specific methyltransferase PhzM (adenosylmethionine dependent methyltransferase) [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_53 61.328 1.16E-111 fepC VF0228 Enterobactin Nutritional/Metabolic factor VFC0272 An extremely effective iron chelator, with a formation constant for the iron complex of 1049. Fe3+ is coordinated by six catechol oxygens to form a metal chelate with a net negative charge of three (fepC) ferrienterobactin ABC transporter ATPase [Enterobactin (VF0228) - Nutritional/Metabolic factor (VFC0272)] [Escherichia coli CFT073] Escherichia coli (UPEC)
JH376461.1_174 98.876 6.36E-61 mucE VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucE) small envelope protein MucE [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_372 99.138 4.26E-82 spcS VF0083 TTSS Effector delivery system VFC0086 (spcS) chaperone for exoS [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_411 99.603 0.0 pilF VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilF) type 4 fimbrial biogenesis protein PilF [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_503 98.996 0.0 lasB VF0087 LasB Effector delivery system VFC0086 Secreted by type II secretion pathway (lasB) elastase LasB [LasB (VF0087) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_577 99.778 0.0 mucP VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucP) metalloprotease protease [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_590 66.784 3.34E-145 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JH376461.1_604 99.701 0.0 rpoS VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (rpoS) RNA polymerase sigma factor RpoS [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_678 100.0 0.0 algA VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algA) phosphomannose isomerase / guanosine 5'-diphospho-D-mannose pyrophosphorylase [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_679 99.02 3.66E-69 algF VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algF) alginate o-acetyltransferase AlgF [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_681 99.728 0.0 algL VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algL) poly(beta-d-mannuronate) lyase precursor AlgL [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_682 99.789 0.0 algX VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algX) alginate biosynthesis protein AlgX [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_683 100.0 0.0 algG VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algG) outer membrane protein AlgE [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_684 99.796 0.0 algE VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algE) alginate biosynthetic protein AlgK precursor [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_685 99.789 0.0 algK VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algK) alginate biosynthesis protein Alg44 [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_686 100.0 0.0 alg44 VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (alg44) alginate biosynthesis protein Alg8 [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_687 100.0 0.0 alg8 VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (alg8) alginate-c5-mannuronan-epimerase AlgG [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_688 100.0 0.0 algD VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algD) GDP-mannose 6-dehydrogenase AlgD [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_702 99.688 0.0 motY VF0273 Flagella Motility VFC0204 (motY) probable outer membrane protein precursor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_723 99.265 0.0 tse3 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse3) type VI secretion system effector Tse3, glycoside hydrolase [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_728 99.661 0.0 rhlA VF0089 Rhamnolipid Immune modulation VFC0258 Nonenzyme glycolipid (rhlA) rhamnosyltransferase chain A [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_729 100.0 0.0 rhlB VF0089 Rhamnolipid Immune modulation VFC0258 Nonenzyme glycolipid (rhlB) rhamnosyltransferase chain B [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_730 100.0 0.0 rhlR VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (rhlR) transcriptional regulator RhlR [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_731 99.005 5.69E-150 rhlI VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (rhlI) autoinducer synthesis protein RhlL [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_861 99.359 3.75E-107 flgN VF0273 Flagella Motility VFC0204 (flgN) flagella synthesis protein FlgN [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_862 99.065 4.14E-74 flgM VF0273 Flagella Motility VFC0204 (flgM) negative regulator of flagellin synthesis [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_863 98.276 1.33E-168 flgA VF0273 Flagella Motility VFC0204 (flgA) flagellar basal body P-ring biosynthesis protein FlgA [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_864 99.032 0.0 PA3349 VF0273 Flagella Motility VFC0204 (PA3349) chemotaxis protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_865 100.0 0.0 PA3348 VF0273 Flagella Motility VFC0204 (PA3348) chemotaxis protein methyltransferase [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1064 68.025 1.38E-159 wzz VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wzz) O-antigen chain length regulator [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1065 85.814 0.0 wbpA VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpA) UDP-N-acetyl-d-glucosamine 6-dehydrogenase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1066 77.07 1.33E-178 wbpB VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpB) UDP-N-acetyl-2-amino-2-deoxy-D-glucuronate oxidase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1067 77.368 1.25E-108 wbpD VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpD) UDP-2-acetamido-3-amino-2, 3-dideoxy-D-glucuronate N-acetyltransferase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1068 72.5 0.0 wbpE VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpE) UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1076 63.303 1.31E-142 wbpL VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpL) glycosyltransferase WbpL [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1077 98.797 0.0 wbpM VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (wbpM) nucleotide sugar epimerase/dehydratase WbpM [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1103 98.81 0.0 fimV VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimV) a polar peptidoglycan-binding protein involved in type IV pilus assembly [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1113 93.769 0.0 xcpQ VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpQ) general secretion pathway protein D [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1114 99.541 3.11E-158 xcpP VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpP) secretion protein XcpP [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1115 100.0 0.0 xcpR VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpR) general secretion pathway protein E [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1116 100.0 0.0 xcpS VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpS) general secretion pathway protein F [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1117 99.324 8.73E-107 xcpT VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpT) general secretion pathway protein G [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1118 99.419 1.04E-120 xcpU VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpU) general secretion pathway protein H [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1119 99.225 1.07E-89 xcpV VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpV) general secretion pathway protein I [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1120 100.0 1.07E-173 xcpW VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpW) general secretion pathway protein J [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1121 99.699 0.0 xcpX VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpX) general secretion pathway protein K [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1122 99.476 0.0 xcpY VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpY) general secretion pathway protein L [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1123 100.0 1.14E-122 xcpZ VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpZ) general secretion pathway protein M [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1250 64.228 2.73E-106 flmH VF0473 Polar flagella Motility VFC0204 Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments (flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
JH376461.1_1251 65.753 1.64E-28 acpXL VF0367 LPS Immune modulation VFC0258 Brucella possesses a non-classical LPS as compared with the so-called classical LPS from enterobacteria such as Escherichia coli. B. abortus lipid A possesses a diaminoglucose backbone (rather than glucosamine), and acyl groups are longer (C28 rather than C12 and C16) and are only linked to the core by amide bounds (rather than ester and amide bonds).; In contrast to enterobacterial LPSs, Brucella LPS is several-hundred-times less active and toxic than E. coli LPS.; this is an evolutionary adaptation to an intracellular lifestyle, low endotoxic activity is shared by other intracellular pathogens such as Bartonella and Legionella. (acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M] Brucella melitensis
JH376461.1_1257 100.0 1.8E-85 pilZ VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilZ) type 4 fimbrial biogenesis protein PilZ [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1546 99.367 2.96E-115 tse2 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse2) type VI secretion system effector Tse2 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1559 63.725 0.0 fepA VF0562 Ent Nutritional/Metabolic factor VFC0272 Various iron acquisition systems in Klebsiella are needed to overcome host defenses in different anatomical compartments. (fepA) outer membrane receptor FepA [Ent (VF0562) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
JH376461.1_1562 74.513 0.0 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1564 99.051 0.0 tse5/rhsP1 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse5/rhsP1) Toxin protein Tse5 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376461.1_1827 67.395 0.0 adeG VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JH376462.1_139 71.023 0.0 mgtB VF0106 MgtB Nutritional/Metabolic factor VFC0272 A magnesium transporter (mgtB) Mg2+ transport protein [MgtB (VF0106) - Nutritional/Metabolic factor (VFC0272)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
JH376462.1_183 61.728 0.0 ureB VF0050 Urease Stress survival VFC0282 (ureB) urease beta subunit UreB, urea amidohydrolase [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JH376462.1_209 67.347 4.7E-102 ureG VF0050 Urease Stress survival VFC0282 (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JH376462.1_269 100.0 0.0 motB VF0273 Flagella Motility VFC0204 (motB) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_270 98.94 0.0 motA VF0273 Flagella Motility VFC0204 (motA) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_276 100.0 0.0 fimX VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimX) protein FimX [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_307 99.294 0.0 waaA VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaA) lipopolysaccharide core biosynthesis protein WaaP [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_328 99.627 0.0 waaP VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaP) UDP-glucose:(heptosyl) LPS alpha 1,3-glucosyltransferase WaaG [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_329 99.464 0.0 waaG VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaG) B-band O-antigen polymerase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_330 100.0 0.0 waaC VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaC) 3-deoxy-D-manno-octulosonic-acid (KDO) transferase [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_331 99.71 0.0 waaF VF0085 LPS Immune modulation VFC0258 Two distinct forms of LPS: A-band and B-band. A-band is a homopolymer of alpha-linked D-rhamnose, whereas B-band LPS is a heteropolymer (waaF) heptosyltransferase I [LPS (VF0085) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_359 100.0 0.0 pilQ VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilQ) type 4 fimbrial biogenesis protein PilQ [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_360 100.0 3.78E-128 pilP VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilP) type IV pilus biogenesis protein PilP [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_361 100.0 2.96E-154 pilO VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilO) type IV pilus inner membrane platform protein PilO [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_362 100.0 7.38E-146 pilN VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilN) type IV pilus inner membrane platform protein PilN [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_363 100.0 0.0 pilM VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilM) type IV pilus inner membrane platform protein PilM [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_409 96.644 0.0 pldB/tle5b VF1350 HSI-3 T6SS secreted effectors Effector delivery system VFC0086 (pldB/tle5b) phospholipase D [HSI-3 T6SS secreted effectors (VF1350) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_486 62.284 1.06E-131 wbtL VF0542 LPS Immune modulation VFC0258 The structure of Francisella spp. lipid A is unique in that it is modified by various carbohydrates that greatly reduce TLR4 activation and allow for immune evasion (wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JH376462.1_581 94.247 0.0 algP/algR3 VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algP/algR3) alginate regulatory protein AlgP [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_583 100.0 1.13E-117 algQ VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algQ) Alginate regulatory protein AlgQ [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_589 100.0 0.0 algR VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algR) alginate biosynthesis regulatory protein AlgR [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_590 100.0 0.0 algZ VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algZ) sigma factor AlgU [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_649 99.08 0.0 algC VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algC) phosphomannomutase AlgC [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376462.1_659 100.0 0.0 crc VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (crc) catabolite repression control protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_1 100.0 4.13E-98 phzA2 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzA2) phenazine biosynthesis protein PhzA [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_32 98.325 0.0 lasA VF0088 LasA Effector delivery system VFC0086 Secreted by type II secretion pathway (lasA) LasA protease precursor [LasA (VF0088) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_61 99.351 1.05E-113 tse1 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse1) type VI secretion system effector Tse1, peptidoglycanhydrolase [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_87 99.822 0.0 fimL VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimL) hypothetical protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_108 62.827 8.71E-91 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
JH376463.1_187 99.065 5.62E-150 pscL VF0083 TTSS Effector delivery system VFC0086 (pscL) type III secretion systemt protein PscL [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_188 98.558 8.74E-146 pscK VF0083 TTSS Effector delivery system VFC0086 (pscK) type III secretion system protein PscK [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_189 99.59 3.84E-178 pscJ VF0083 TTSS Effector delivery system VFC0086 (pscJ) type III secretion system inner MS ring protein [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_190 99.107 9.39E-78 pscI VF0083 TTSS Effector delivery system VFC0086 (pscI) type III secretion system inner rod protein PscI [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_191 99.301 4.54E-98 pscH VF0083 TTSS Effector delivery system VFC0086 (pscH) type III secretion system protein PscH [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_192 99.13 8.11E-80 pscG VF0083 TTSS Effector delivery system VFC0086 (pscG) type III secretion system chaperone PscG for PscF [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_193 100.0 3.43E-58 pscF VF0083 TTSS Effector delivery system VFC0086 (pscF) type III secretion system needle filament protein PscF [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_194 97.015 1.96E-40 pscE VF0083 TTSS Effector delivery system VFC0086 (pscE) type III secretion system cochaperone PscE for PscG [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_195 98.38 0.0 pscD VF0083 TTSS Effector delivery system VFC0086 (pscD) type III secretion system basal body protein PscD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_196 99.833 0.0 pscC VF0083 TTSS Effector delivery system VFC0086 (pscC) type III secretion system secretin PscC [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_197 99.286 1.56E-92 pscB VF0083 TTSS Effector delivery system VFC0086 (pscB) type III secretion system protein PscB [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_198 99.275 0.0 exsD VF0083 TTSS Effector delivery system VFC0086 (exsD) type III secretion system regulatory protein ExsD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_199 100.0 0.0 exsA VF0083 TTSS Effector delivery system VFC0086 (exsA) type III secretion system regulatory protein ExsA [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_200 98.54 6.87E-95 exsB VF0083 TTSS Effector delivery system VFC0086 (exsB) type III secretion system pilotin ExsB [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_201 97.531 5.65E-53 exsE VF0083 TTSS Effector delivery system VFC0086 (exsE) type III secretion system regulatory protein ExsE [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_202 100.0 3.05E-103 exsC VF0083 TTSS Effector delivery system VFC0086 (exsC) type III secretion system regulatory protein ExsC [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_203 98.305 0.0 popD VF0083 TTSS Effector delivery system VFC0086 (popD) type III secretion system hydrophobic translocator, pore protein PopD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_204 98.974 0.0 popB VF0083 TTSS Effector delivery system VFC0086 (popB) type III secretion system hydrophobic translocator, pore protein PopB [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_205 98.214 2.13E-118 pcrH VF0083 TTSS Effector delivery system VFC0086 (pcrH) type III secretion system regulatory protein PcrH [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_206 98.98 0.0 pcrV VF0083 TTSS Effector delivery system VFC0086 (pcrV) type III secretion system hydrophilic translocator, needle tip protein PcrV [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_207 98.98 5.31E-64 pcrG VF0083 TTSS Effector delivery system VFC0086 (pcrG) type III secretion system cytoplasmic regulator PcrG [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_208 100.0 6.66E-103 pcrR VF0083 TTSS Effector delivery system VFC0086 (pcrR) type III secretion system regulatory protein PcrR [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_209 100.0 0.0 pcrD VF0083 TTSS Effector delivery system VFC0086 (pcrD) type III secretion system protein PcrD [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_210 100.0 1.69E-70 pcr4 VF0083 TTSS Effector delivery system VFC0086 (pcr4) type III secretion system protein Pcr4 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_211 99.174 7.74E-83 pcr3 VF0083 TTSS Effector delivery system VFC0086 (pcr3) type III secretion system protein Pcr3 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_212 99.187 6.22E-85 pcr2 VF0083 TTSS Effector delivery system VFC0086 (pcr2) type III secretion system protein Pcr2 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_213 100.0 1.02E-63 pcr1 VF0083 TTSS Effector delivery system VFC0086 (pcr1) type III secretion system protein Pcr1 [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_215 99.534 0.0 pscN VF0083 TTSS Effector delivery system VFC0086 (pscN) type III secretion system ATPase PscN [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_216 99.367 1.86E-103 pscO VF0083 TTSS Effector delivery system VFC0086 (pscO) type III secretion system protein PscO [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_217 99.242 6.88E-89 pscP VF0083 TTSS Effector delivery system VFC0086 (pscP) type III secretion system protein PscP [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_218 98.058 0.0 pscQ VF0083 TTSS Effector delivery system VFC0086 (pscQ) type III secretion system protein PscQ [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_219 100.0 5.21E-158 pscR VF0083 TTSS Effector delivery system VFC0086 (pscR) type III secretion system protein PscR [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_220 100.0 1.14E-57 pscS VF0083 TTSS Effector delivery system VFC0086 (pscS) type III secretion system protein PscS [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_221 99.237 0.0 pscT VF0083 TTSS Effector delivery system VFC0086 (pscT) type III secretion system protein PscT [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_222 99.427 0.0 pscU VF0083 TTSS Effector delivery system VFC0086 (pscU) type III secretion system protein PscU [TTSS (VF0083) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_242 99.392 0.0 stk1 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (stk1) serine-threonine kinase Stk1 [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_243 99.174 1.05E-174 stp1 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (stp1) serine/threonine phosphoprotein phosphatase Stp1 [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_244 99.66 0.0 tssM VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssM) type VI secretion system membrane subunit TssM [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_245 100.0 0.0 icmH/tssL VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (icmH/tssL) type IVB secretion system protein IcmH/DotU [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_246 99.549 0.0 tssK VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssK) type VI secretion system baseplate subunit TssK [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_247 99.405 3.74E-118 tssJ VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssJ) type VI secretion system lipoprotein TssJ [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_248 97.985 0.0 PA1665 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (PA1665) hypothetical protein [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_249 100.0 2.58E-30 PA1664 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (PA1664) hypothetical protein [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_250 98.901 0.0 PA1663 VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (PA1663) transcriptional regulator [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_251 99.771 0.0 tssH VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssH) type VI secretion system ATPase TssH [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_252 99.403 0.0 tssG VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssG) type VI secretion system baseplate subunit TssG [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_254 99.259 1.03E-96 tssE VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssE) type VI secretion system baseplate subunit TssE [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_255 100.0 0.0 tssC VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssC) type VI secretion system contractile sheath large subunit [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_256 100.0 3.42E-119 tssB VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssB) type VI secretion system contractile sheath small subunit [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_257 100.0 0.0 tssA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssA) type VI secretion system protein TssA [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_409 100.0 3.88E-100 hcpA VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (hcpA) Hcp family type VI secretion system effector [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_410 99.169 0.0 vgrG VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (vgrG) type VI secretion system tip protein VgrG [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_458 100.0 2.34E-115 PA1464 VF0273 Flagella Motility VFC0204 (PA1464) purine-binding chemotaxis protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_461 100.0 0.0 motD VF0273 Flagella Motility VFC0204 (motD) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_462 100.0 9.14E-176 motC VF0273 Flagella Motility VFC0204 (motC) flagellar motor protein [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_463 98.641 0.0 PA1459 VF0273 Flagella Motility VFC0204 (PA1459) chemotaxis-specific methylesterase [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_464 99.602 0.0 PA1458 VF0273 Flagella Motility VFC0204 (PA1458) two-component sensor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_465 100.0 0.0 cheZ VF0273 Flagella Motility VFC0204 (cheZ) protein phosphatase CheZ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_466 100.0 5.08E-90 cheY VF0273 Flagella Motility VFC0204 (cheY) chemotaxis protein CheY [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_467 100.0 3.38E-177 fliA VF0273 Flagella Motility VFC0204 (fliA) flagellar biosynthesis sigma factor FliA [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_468 100.0 0.0 fleN VF0273 Flagella Motility VFC0204 (fleN) flagellar synthesis regulator FleN [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_469 98.834 0.0 flhF VF0273 Flagella Motility VFC0204 (flhF) flagellar biosynthesis protein FlhF [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_470 99.859 0.0 flhA VF0273 Flagella Motility VFC0204 (flhA) flagellar biosynthesis protein FlhA [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_473 99.715 0.0 flhB VF0273 Flagella Motility VFC0204 (flhB) flagellar biosynthetic protein FlhB [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_474 99.225 8.84E-180 fliR VF0273 Flagella Motility VFC0204 (fliR) flagellar biosynthetic protein FliR [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_475 100.0 1.48E-57 fliQ VF0273 Flagella Motility VFC0204 (fliQ) flagellar biosynthetic protein FliQ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_476 99.608 0.0 fliP VF0273 Flagella Motility VFC0204 (fliP) flagellar biosynthetic protein FliP [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_477 100.0 3.57E-103 fliO VF0273 Flagella Motility VFC0204 (fliO) flagellar protein FliO [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_478 100.0 1.09E-111 fliN VF0273 Flagella Motility VFC0204 (fliN) flagellar motor switch protein FliN [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_479 100.0 0.0 fliM VF0273 Flagella Motility VFC0204 (fliM) flagellar motor switch protein FliM [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_480 100.0 2.92E-125 fliL VF0273 Flagella Motility VFC0204 (fliL) flagellar basal body protein FliL [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_481 99.297 0.0 fliK VF0273 Flagella Motility VFC0204 (fliK) flagellar hook-length control protein FliK [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_491 100.0 1.49E-152 lasI VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (lasI) autoinducer synthesis protein LasI [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_493 100.0 0.0 lasR VF0093 Quorum sensing Biofilm VFC0271 Consists of two separate but interrelated systems, las and rhl. The autoinducer signal molecules produced by P.aeruginosa are N-(3-oxododencanoyl) homeserine lactone(3O-C12-HSL) and N-butyryl homoserine lactone(C4-HSL); a novel, additional autoinducer has recently been demonstrated to be involved in quorum sensing. It is 2-heptyl-3-hydroxy-4-quinolone, an additional link between the Las and Rhl circuits (lasR) transcriptional regulator LasR [Quorum sensing (VF0093) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376463.1_666 99.582 0.0 aprA VF0090 Alkaline protease Exoenzyme VFC0251 Secreted by type I secretion pathway (aprA) alkaline metalloproteinase precursor [Alkaline protease (VF0090) - Exoenzyme (VFC0251)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_6 99.781 0.0 exoT VF0853 TTSS secreted effectors Effector delivery system VFC0086 (exoT) type III secretion system effector ExoT, ADP ribosyltransferase activity and GTPase-activating protein activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_14 99.672 0.0 phzH VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzH) phenazine-modifying enzyme [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_32 98.355 0.0 tagQ VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagQ) type VI secretiona ssociated protein TagQ, outer membrane lipoprotein [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_33 99.825 0.0 tagR VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagR) type VI secretion associated protein TagR, positively regulates PpkA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_34 100.0 0.0 tagS VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagS) type VI secretion associated protein TagS, forming a stable inner membrane complex with TagT [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_35 99.582 1.68E-167 tagT VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagT) type VI secretion associated protein TagT, ATP-binding component of ABC transporter [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_36 98.803 0.0 ppkA VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (ppkA) serine/threonine protein kinase PpkA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_38 99.587 2.45E-176 pppA VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (pppA) Pseudomonas protein phosphatase PppA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_39 99.558 5.65E-163 tagF/pppB VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (tagF/pppB) Pseudomonas protein phosphatase PppB [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_40 99.456 0.0 icmF1/tssM1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (icmF1/tssM1) type VI secretion system protein IcmF1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_41 100.0 0.0 dotU1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (dotU1) type VI secretion system protein DotU [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_42 100.0 0.0 hsiJ1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiJ1) type VI secretion system hcp secretion island protein HsiJ1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_43 100.0 9.67E-112 lip1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (lip1) lipoprotein [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_44 96.505 0.0 fha1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (fha1) type VI secretion system forkhead-associated protein Fha1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_45 99.709 0.0 hsiA1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiA1) type VI secretion system hcp secretion island protein HsiA1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_46 100.0 4.29E-125 hsiB1/vipA/tssB VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiB1/vipA/tssB) type VI secretion system tubule-forming protein VipA [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_47 99.799 0.0 hsiC1/vipB/tssC VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiC1/vipB/tssC) type VI secretion system tubule-forming protein VipB [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_48 100.0 2.12E-120 hcp1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hcp1) type VI secretion system substrate Hcp1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_49 100.0 0.0 hsiE1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiE1) type VI secretion system hcp secretion island protein HsiE1, interacting with HsiB1 to form a novel subcomplex of the T6SS [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_50 99.408 1.65E-120 hsiF1/tssE VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiF1/tssE) type VI secretion system hcp secretion island protein HsiF1, a gp25-like protein, but not exhibit lysozyme activity [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_51 99.677 0.0 hsiG1/tssF VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiG1/tssF) type VI secretion system hcp secretion island protein HsiG1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_52 99.138 0.0 hsiH1/tssG VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (hsiH1/tssG) type VI secretion system hcp secretion island protein HsiH1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_53 99.667 0.0 clpV1 VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (clpV1) type VI secretion system AAA+ family ATPase [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_54 99.689 0.0 vgrG1a VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1a) type VI secretion system substrate VgrG1 [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_59 99.535 0.0 tse6 VF1194 HSI-1 T6SS secreted effectors Effector delivery system VFC0086 (tse6) NAD(P)(+) glycohydrolase toxin Tse6 [HSI-1 T6SS secreted effectors (VF1194) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_61 99.19 0.0 vgrG1b VF0334 HSI-1 Effector delivery system VFC0086 HSI-1 is highly homologous to a group of genes found in many Gram-negative proteobacteria that have been termed the IcmF-associated homologous protein (IAHP) cluster and encodes a secretory system that may play a general role in mediating host interaction (vgrG1b) type VI secretion system substrate VgrG1b [HSI-1 (VF0334) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_146 66.242 9.28E-71 cheW VF0430 Flagella Motility VFC0204 (cheW) chemotaxis protein CheW [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243] Burkholderia pseudomallei
JH376464.1_147 60.106 5.67E-157 cheA VF0430 Flagella Motility VFC0204 (cheA) chemotaxis two-component sensor kinase CheA [Flagella (VF0430) - Motility (VFC0204)] [Burkholderia pseudomallei K96243] Burkholderia pseudomallei
JH376464.1_361 100.0 0.0 pilT VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilT) twitching motility protein PilT [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_362 99.738 0.0 pilU VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilU) twitching motility protein PilU [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_374 100.0 2.88E-98 pilG VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilG) twitching motility protein PilG [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_375 100.0 4.33E-87 pilH VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilH) twitching motility protein PilH [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_376 100.0 6.64E-130 pilI VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilI) twitching motility protein PilI [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_377 99.853 0.0 pilJ VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilJ) twitching motility protein PilJ [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_378 99.656 0.0 pilK VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilK) methyltransferase PilK [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_379 98.83 0.0 chpA VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpA) still frameshift probable component of chemotactic signal transduction system [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_380 99.125 0.0 chpB VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpB) probable methylesterase [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_381 98.214 1.02E-115 chpC VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpC) probable chemotaxis protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_382 100.0 0.0 chpD VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpD) probable transcriptional regulator [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_383 100.0 5.4E-142 chpE VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (chpE) probable chemotaxis protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376464.1_392 71.344 0.0 acrB VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
JH376464.1_578 63.801 7.18E-99 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JH376464.1_609 100.0 4.07E-160 vfr VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (vfr) cAMP-regulatory protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_99 100.0 4.9E-143 algU VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_100 100.0 3.9E-141 mucA VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucA) alkaline metalloproteinase precursor [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_101 99.684 0.0 mucB VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucB) anti-sigma factor MucA, inhibitor of alg gene expression [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_103 99.578 0.0 mucD VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (mucD) serine protease MucD precursor [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_188 99.178 0.0 plcH VF0092 PLC Exotoxin VFC0235 (plcH) hemolytic phospholipase C precursor [PLC (VF0092) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_251 73.333 4.53E-30 csrA VF0261 CsrA Regulation VFC0301 Belongs to a highly conserved family of global regulators that typically control stationary phase traits post-transcriptionally (csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JH376465.1_277 60.545 0.0 iroN VF0563 Sal Nutritional/Metabolic factor VFC0272 Salmochelin is a glycosylated Ent that requires the iroA locus for production and transport (iroN) salmochelin receptor IroN [Sal (VF0563) - Nutritional/Metabolic factor (VFC0272)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
JH376465.1_312 63.525 7.28E-113 CBU_1566 VF0696 T4SS secreted effectors Effector delivery system VFC0086 (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] Coxiella burnetii
JH376465.1_326 100.0 0.0 exoU VF0853 TTSS secreted effectors Effector delivery system VFC0086 (exoU) type III secretion system effector ExoU, phospholipase A2 activity [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa UCBPP-PA14] Pseudomonas aeruginosa
JH376465.1_421 100.0 7.62E-99 flgB VF0273 Flagella Motility VFC0204 (flgB) flagellar basal body rod protein FlgB [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_422 100.0 3.05E-107 flgC VF0273 Flagella Motility VFC0204 (flgC) flagellar basal-body rod protein FlgC [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_423 100.0 3.49E-172 flgD VF0273 Flagella Motility VFC0204 (flgD) flagellar basal-body rod modification protein FlgD [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_424 99.784 0.0 flgE VF0273 Flagella Motility VFC0204 (flgE) flagellar hook protein FlgE [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_425 100.0 0.0 flgF VF0273 Flagella Motility VFC0204 (flgF) flagellar basal-body rod protein FlgF [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_426 100.0 0.0 flgG VF0273 Flagella Motility VFC0204 (flgG) flagellar basal-body rod protein FlgG [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_427 100.0 7.18E-172 flgH VF0273 Flagella Motility VFC0204 (flgH) flagellar L-ring protein precursor FlgH [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_428 100.0 0.0 flgI VF0273 Flagella Motility VFC0204 (flgI) flagellar P-ring protein precursor FlgI [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_429 99.75 0.0 flgJ VF0273 Flagella Motility VFC0204 (flgJ) flagellar rod assembly protein/muramidase FlgJ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_430 87.555 0.0 flgK VF0273 Flagella Motility VFC0204 (flgK) flagellar hook-associated protein 1 FlgK [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_431 67.58 0.0 flgL VF0273 Flagella Motility VFC0204 (flgL) flagellar hook-associated protein 3 FlgL [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_445 66.4 5.76E-45 fliS VF0273 Flagella Motility VFC0204 (fliS) flagellar protein FliS [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_447 100.0 0.0 fleQ VF0273 Flagella Motility VFC0204 (fleQ) transcriptional regulator FleQ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_448 99.751 0.0 fleS VF0273 Flagella Motility VFC0204 (fleS) two-component sensor [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_449 100.0 0.0 fleR VF0273 Flagella Motility VFC0204 (fleR) two-component response regulator [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_450 100.0 7.9E-76 fliE VF0273 Flagella Motility VFC0204 (fliE) flagellar hook-basal body complex protein FliE [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_451 100.0 0.0 fliF VF0273 Flagella Motility VFC0204 (fliF) flagellar M-ring protein FliF [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_452 100.0 0.0 fliG VF0273 Flagella Motility VFC0204 (fliG) flagellar motor switch protein G [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_453 100.0 0.0 fliH VF0273 Flagella Motility VFC0204 (fliH) flagellar assembly protein H [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_454 99.778 0.0 fliI VF0273 Flagella Motility VFC0204 (fliI) flagellum-specific ATP synthase FliI [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_455 98.639 4.28E-102 fliJ VF0273 Flagella Motility VFC0204 (fliJ) flagellar protein FliJ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_484 99.692 0.0 rhlC VF0089 Rhamnolipid Immune modulation VFC0258 Nonenzyme glycolipid (rhlC) rhamnosyltransferase 2 [Rhamnolipid (VF0089) - Immune modulation (VFC0258)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_502 99.216 0.0 toxA VF0086 ExoA Exotoxin VFC0235 Secreted by type II secretion pathway; transported to the endoplasmic reticulum (ER) via a coat protein COPI-dependent retrograde pathway dependent on a KDEL motif (toxA) exotoxin A precursor [ExoA (VF0086) - Exotoxin (VFC0235)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376465.1_510 68.803 2.2E-110 bfmR VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JH376466.1_46 100.0 0.0 fapF VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapF) outer membrane secretin FapF [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_47 98.8 1.34E-179 fapE VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapE) chaprone FapE [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_48 99.558 1.13E-167 fapD VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapD) periplasmic accessory protein FapD [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_49 99.412 0.0 fapC VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapC) major amyloid subunit FapC [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_50 97.884 4.36E-128 fapB VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapB) minor amyloid subunit FapB [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_51 96.319 9.22E-106 fapA VF1191 Fap Adherence VFC0001 The Fap system displays many similarities to the curli system, but the two are not evolutionary related (fapA) periplasmic accessory protein FapA [Fap (VF1191) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_288 98.765 0.0 exoY VF0853 TTSS secreted effectors Effector delivery system VFC0086 (exoY) type III secretion system effector ExoY, adenylate cyclase [TTSS secreted effectors (VF0853) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_351 99.695 0.0 pvcA VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcA) paerucumarin biosynthesis protein PvcA [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_352 98.969 0.0 pvcB VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcB) paerucumarin biosynthesis protein PvcB [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_353 99.4 0.0 pvcC VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcC) paerucumarin biosynthesis protein PvcC [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_354 98.605 1.45E-156 pvcD VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvcD) paerucumarin biosynthesis protein PvcD [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376466.1_355 99.038 0.0 ptxR VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (ptxR) transcriptional regulator PtxR [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376467.1_78 98.621 0.0 xcpA/pilD VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (xcpA/pilD) type 4 prepilin peptidase PilD [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376467.1_79 60.891 2.29E-176 pilC VF1334 TFP Adherence VFC0001 (pilC) type II secretion system F family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JH376467.1_80 100.0 0.0 pilB VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilB) type 4 fimbrial biogenesis protein PilB [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376467.1_88 60.971 0.0 ibeC VF0237 Ibes Invasion VFC0083 IbeA is unique to E. coli K1. The ibeB and ibeC are found to have K12 homologues p77211 and yijP respectively. (ibeC) phosphoethanolamine transferase CptA [Ibes (VF0237) - Invasion (VFC0083)] [Escherichia coli O45:K1:H7 str. S88] Escherichia coli (NMEC)
JH376467.1_143 99.799 0.0 rpoN VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (rpoN) RNA polymerase factor sigma-54 [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376467.1_160 99.486 0.0 algW VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algW) AlgW protein [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376467.1_221 76.908 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JH376467.1_241 66.492 3.06E-99 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JH376468.1_117 99.777 0.0 algB VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algB) two-component response regulator AlgB [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_67 65.242 1.33E-160 PA2359 VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (PA2359) transcriptional regulator [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_72 99.446 0.0 PA2359 VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (PA2359) transcriptional regulator [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_73 97.814 0.0 tssA VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssA) type VI secretion system protein TssA [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_74 98.033 0.0 tssM VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssM) type VI secretion system membrane subunit [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_76 98.598 3.56E-147 tssK VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssK) type VI secretion system baseplate subunit TssK [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_77 98.936 1.35E-129 tssK VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssK) type VI secretion system baseplate subunit TssK [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_78 99.367 3.48E-116 PA2364 VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (PA2364) hypothetical protein [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_79 100.0 1.72E-129 tssB VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssB) type VI secretion system contractile sheath small subunit [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_80 100.0 0.0 tssC VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssC) type VI secretion system contractile sheath large subunit [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_81 100.0 1.26E-122 hcp/tssD VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (hcp/tssD) Hcp family type VI secretion system effector [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_82 96.454 6.54E-93 tssE VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssE) type VI secretion system baseplate subunit TssE [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_83 99.497 0.0 tssF VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssF) type VI secretion system baseplate subunit TssF [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_84 99.704 0.0 tssG VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssG) type VI secretion system baseplate subunit TssG [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_85 99.411 0.0 tssH VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssH) type VI secretion system ATPase TssH [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_88 96.407 0.0 tssI VF0944 HSI-3 Effector delivery system VFC0086 The expression of T6SSs in P. aeruginosa is regulated by the QS system. There are several QS systems in P. aeruginosa, two N-acyl-homoserine lactone based QS systems (las and rhl systems) and one quinolone PQS system (pqs). The expression of H1-T6SS is negatively regulated by both las and pqs QS systems, while the expression of H2- and H3-T6SS is positively regulated by las, rhl, and pqs (tssI) type VI secretion system tip protein VgrG [HSI-3 (VF0944) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_96 99.673 0.0 PA2383 VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (PA2383) transcriptional regulator [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_97 100.0 2.14E-74 PA2384 VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (PA2384) hypothetical protein [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_98 98.582 0.0 pvdQ VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdQ) 3-oxo-C12-homoserine lactone acylase PvdQ [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_99 99.034 4.03E-149 pvdA VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdA) L-ornithine N5-oxygenase PvdA [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_101 100.0 4.19E-115 fpvI VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (fpvI) RNA polymerase sigma factor [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_103 98.876 1.78E-56 fpvR VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (fpvR) protein FpvR [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_107 99.816 0.0 pvdP VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdP) tyrosinase required for pyoverdine maturation [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_108 100.0 0.0 pvdM VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdM) dipeptidase precursor [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_109 99.766 0.0 pvdN VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdN) pyoverdine biosynthesis protein PvdN [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_110 99.296 0.0 pvdO VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdO) pyoverdine biosynthesis protein PvdO [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_111 100.0 0.0 pvdF VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdF) pyoverdine synthetase F [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_112 100.0 0.0 pvdE VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdE) pyoverdine biosynthesis protein PvdE [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_113 99.75 0.0 fpvA VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (fpvA) ferripyoverdine receptor FpvA [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_115 99.768 0.0 pvdJ VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdJ) pyoverdine biosynthesis protein PvdJ [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_130 100.0 4.21E-52 mbtH-like VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (mbtH-like) MbtH-like protein from the pyoverdine cluster [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_131 99.787 0.0 pvdH VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdH) diaminobutyrate-2-oxoglutarate aminotransferase PvdH [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_143 99.447 0.0 pvdL VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdL) peptide synthase PvdL [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_144 99.213 0.0 pvdG VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdG) pyoverdine biosynthesis protein PvdG [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_145 100.0 2.14E-141 pvdS VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdS) extracytoplasmic-function sigma-70 factor [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376469.1_146 100.0 1.47E-110 pvdY VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdY) hypothetical protein [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_144 100.0 5.49E-103 pilE VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilE) type 4 fimbrial biogenesis protein PilE [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_145 100.0 1.69E-84 pilY2 VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilY2) type 4 fimbrial biogenesis protein PilY2 [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_146 93.476 0.0 pilY1 VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilY1) type 4 fimbrial biogenesis protein PilY1 [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_147 98.974 8.47E-143 pilX VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilX) type 4 fimbrial biogenesis protein PilX [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_148 100.0 0.0 pilW VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilW) type IV fimbrial biogenesis protein PilW [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_149 98.378 1.75E-136 pilV VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilV) type IV pilus biogenesis protein PilV [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_150 98.81 3.32E-123 fimU VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimU) type 4 fimbrial biogenesis protein FimU [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_151 96.45 1.24E-116 fimT VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (fimT) type 4 fimbrial biogenesis protein FimT [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_153 100.0 0.0 pilR VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilR) two-component response regulator PilR [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376470.1_154 99.811 0.0 pilS VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (pilS) two-component sensor PilS [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_1 100.0 1.63E-53 phzG1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzG1) phenazine biosynthesis protein PhzG, pyridoxamine 5'-phosphate oxidase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_2 99.254 0.0 phzS VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzS) flavin dependent hydroxylase PhzS [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_3 99.758 0.0 PA4218 VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (PA4218) transporter [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_4 98.403 0.0 PA4219 VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (PA4219) hypothetical protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_6 100.0 0.0 fptA VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (fptA) Fe(III)-pyochelin receptor precursor [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_7 98.398 0.0 pchI VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchI) ABC transporter ATP-binding protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_9 97.189 2.0E-155 pchF VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchF) pyochelin synthetase PchF [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_10 99.175 0.0 pchF VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchF) pyochelin synthetase PchF [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_11 98.887 0.0 pchE VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchE) dihydroaeruginoic acid synthetase PchE [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_12 100.0 0.0 pchR VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchR) transcriptional regulator PchR [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_13 99.086 0.0 pchD VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchD) pyochelin biosynthesis protein PchD [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376471.1_19 69.102 0.0 katA VF0454 KatA Stress survival VFC0282 (katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58] Neisseria meningitidis
JH376471.1_48 88.372 7.78E-51 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JH376474.1_2 100.0 2.79E-159 phzG2 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzG2) pyridoxamine 5'-phosphate oxidase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376474.1_3 100.0 0.0 phzF1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzF1) phenazine biosynthesis protein PhzF, isomerase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376474.1_4 99.841 0.0 phzE1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzE1) phenazine biosynthesis protein PhzE [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376474.1_5 100.0 6.37E-155 phzD1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzD1) phenazine biosynthesis protein PhzD, isochorismatase [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376474.1_6 100.0 0.0 phzC1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzC1) phenazine biosynthesis protein PhzC [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376474.1_7 89.286 9.96E-72 phzB1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzB1) phenazine biosynthesis protein PhzB [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376481.1_1 99.416 0.0 pvdD VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdD) pyoverdine synthetase D [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376484.1_3 86.567 1.26E-81 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JH376486.1_1 100.0 9.88E-36 pvdJ VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdJ) pyoverdine biosynthesis protein PvdJ [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376486.1_2 99.357 0.0 pvdD VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdD) pyoverdine synthetase D [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376487.1_2 60.448 3.25E-105 xcpR VF0084 Xcp secretion system Effector delivery system VFC0086 (xcpR) general secretion pathway protein E [Xcp secretion system (VF0084) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376490.1_1 100.0 7.52E-47 pchI VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchI) ABC transporter ATP-binding protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376490.1_2 98.062 2.21E-173 pchH VF0095 Pyochelin Nutritional/Metabolic factor VFC0272 The genes for pyochelin biosynthesis are in two separate operons, pchDCBA, involved in the synthesis of the pyochelin precursor salicylic acid and pchEFGHI. pchHI appear to have an export function. The fptA gene encoding the 75 kDa ferric pyochelin receptor occurs immediately downstream of pchI (pchH) ABC transporter ATP-binding protein [Pyochelin (VF0095) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376491.1_1 99.045 0.0 pvdI VF0094 Pyoverdine Nutritional/Metabolic factor VFC0272 A greenish-yellow compound, a hydroxyquinolone chromophore to which an amino acid tail is attached, the tail can vary in length; the synthesis of pyoverdine requires a special sigma factor, PvdS, which is in turn regulated by the Fur repressor; also called pseudobactin (pvdI) peptide synthase [Pyoverdine (VF0094) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376493.1_1 78.025 4.85E-171 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JH376494.1_1 99.383 9.06E-123 phzB1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzB1) phenazine biosynthesis protein PhzB [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376494.1_2 100.0 8.55E-95 phzA1 VF0100 Pyocyanin Nutritional/Metabolic factor VFC0272 One of the secreted pigments that give P.aeruginosa laboratory cultures their characteristic blue-green color. It is a redox-cycling compound consisting of modified phenazine ring that is derived from anthrinilate; The precursor molecule of pyocyanin is chorismic acid, the end product on the shikimate pathway. The conversion of chorismic acid to phenazine-1-carboxylic acid (PCA) is controlled by seven genes, encoded by two operons (phzA1B1C1D1E1F1G1 and phzA2B2C2D2E2F2G2). PCA is converted to 5-methylphenazine-1-carboxylic acid betaine (MPCBA), by means of a phenazine-specific methyltransferase (PhzM). In the second step, MPCBA is catalysed by flavin-dependent monooxygenase (PhzS), involving the hydroxylation of the MPCBA betaine to 1-hydroxy-5-methyl phenazine, i.e., pyocyanin. (phzA1) phenazine biosynthesis protein PhzA [Pyocyanin (VF0100) - Nutritional/Metabolic factor (VFC0272)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JH376507.1_1 78.392 1.32E-114 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JH376509.1_1 80.102 2.39E-114 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis