2. PATHOGENS
Basic Information
Accession number
GCA_001007775.1
Release date
2015-05-14
Organism
Acinetobacter baumannii
Species name
Acinetobacter baumannii
Assembly level
Contig
Assembly name
ASM100777v1
Assembly submitter
Translational Genomics Research Institute
Assembly Type
haploid
Genome size
4.1 Mb
GC percent
39.0
Contig count
63
Collection date
2011
Sample location
Argentina
Host
Homo sapiens
Isolation source
Pleural fluid
Isolate type
-
Strain
741019
Isolate
-
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
JZBZ01000006.1_2 # 361 # 1512 700.0 782.711 ADC-5 99.48 ARO:3003851 protein homolog model cephalosporin antibiotic inactivation ADC beta-lactamase without carbapenemase activity ADC-5 is a beta-lactamase found in Acinetobacter pittii.
JZBZ01000008.1_134 # 137894 # 138718 500.0 566.614 OXA-64 100.0 ARO:3001613 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-64 is a beta-lactamase found in A. baumannii.
JZBZ01000009.1_58 # 67069 # 68517 900.0 959.133 adeH 99.38 ARO:3000779 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeH is the outer membrane channel protein of the AdeFGH multidrug efflux complex.
JZBZ01000009.1_59 # 68530 # 71709 750.0 2138.23 adeF 99.91 ARO:3000777 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH.
JZBZ01000009.1_60 # 71716 # 72933 800.0 808.905 adeG 99.51 ARO:3000778 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeG is the inner membrane transporter of the AdeFGH multidrug efflux complex.
JZBZ01000009.1_61 # 73131 # 74162 650.0 694.501 adeL 100.0 ARO:3000620 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeL is a regulator of AdeFGH in Acinetobacter baumannii. AdeL mutations are associated with AdeFGH overexpression and multidrug resistance.
JZBZ01000009.1_66 # 77471 # 77800 175.0 209.92 abeS 100.0 ARO:3000768 protein homolog model macrolide antibiotic; aminocoumarin antibiotic antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump AbeS in an efflux pump of the SMR family of transporters found in Acinetobacter baumannii.
JZBZ01000009.1_328 # 365772 # 367250 600.0 959.518 Acinetobacter baumannii AmvA 98.58 ARO:3004577 protein homolog model macrolide antibiotic; disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AmvA has 14 alpha-helical transmembrane segments, qualifying it as a member of the DHA2 transporter family of the major facilitator superfamily (MFS). When AmvA was expressed in E. coli, the cells had at least four-fold decreased susceptibility to erythromycin, acridine orange, acriflavine, deoxycholate and methyl viologen. AmvA from the AC0037 strain of A. baumannii was tested.
JZBZ01000012.1_37 # 33558 # 36668 2000.0 2084.3 adeB 99.71 ARO:3000775 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeB is the multidrug transporter of the adeABC efflux system.
JZBZ01000012.1_38 # 36665 # 37855 750.0 793.112 adeA 98.48 ARO:3000774 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeA is the membrane fusion protein of the multidrug efflux complex AdeABC.
JZBZ01000012.1_39 # 38001 # 38744 480.0 504.212 adeR 99.6 ARO:3000553 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeR is a positive regulator of AdeABC efflux system. AdeR inactivation leads to susceptibility to aminoglycoside antibiotics.
JZBZ01000012.1_40 # 38776 # 39849 700.0 704.516 adeS 96.08 ARO:3000549 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeS is a sensor kinase in the AdeRS regulatory system of AdeABC. It is essential for AdeABC expression.
JZBZ01000014.1_94 # 98181 # 99281 700.0 736.873 LpsB 97.27 ARO:3005051 protein homolog model peptide antibiotic reduced permeability to antibiotic Intrinsic peptide antibiotic resistant Lps LpsB is involved in lipopolysaccharide synthesis. It confers intrinsic resistance to colistin and other peptide antibiotics.
JZBZ01000014.1_129 # 139652 # 140998 850.0 887.1 abeM 99.78 ARO:3000753 protein homolog model fluoroquinolone antibiotic; disinfecting agents and antiseptics antibiotic efflux multidrug and toxic compound extrusion (MATE) transporter AbeM is an multidrug efflux pump found in Acinetobacter baumannii.
JZBZ01000017.1_1 # 97 # 963 500.0 529.635 sul2 100.0 ARO:3000412 protein homolog model sulfonamide antibiotic antibiotic target replacement sulfonamide resistant sul Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria, usually found on small plasmids.
JZBZ01000017.1_3 # 1578 # 2783 700.0 786.563 tet(B) 99.5 ARO:3000166 protein homolog model tetracycline antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline, doxycycline, and minocycline, but not tigecycline.
JZBZ01000017.1_8 # 6156 # 6992 500.0 568.155 APH(6)-Id 99.64 ARO:3002660 protein homolog model aminoglycoside antibiotic antibiotic inactivation APH(6) APH(6)-Id is an aminoglycoside phosphotransferase encoded by plasmids, integrative conjugative elements and chromosomal genomic islands in K. pneumoniae, Salmonella spp., E. coli, Shigella flexneri, Providencia alcalifaciens, Pseudomonas spp., V. cholerae, Edwardsiella tarda, Pasteurella multocida and Aeromonas bestiarum.
JZBZ01000017.1_9 # 6992 # 7795 500.0 541.191 APH(3'')-Ib 99.63 ARO:3002639 protein homolog model aminoglycoside antibiotic antibiotic inactivation APH(3'') APH(3'')-Ib is an aminoglycoside phosphotransferase encoded by plasmids, transposons, integrative conjugative elements and chromosomes in Enterobacteriaceae and Pseudomonas spp.
JZBZ01000023.1_39 # 34885 # 35673 200.0 374.015 ANT(3'')-IIc 69.77 ARO:3004091 protein homolog model aminoglycoside antibiotic antibiotic inactivation ANT(3'') ANT(3'')-IIc is a aminoglycoside nucleotidyltransferase identified in Acinetobacter spp. via horizontal gene transfer mechanisms.
JZBZ01000024.1_1 # 295 # 867 330.0 389.037 AAC(6')-Ian 100.0 ARO:3003200 protein homolog model aminoglycoside antibiotic antibiotic inactivation AAC(6') AAC(6')-Ian is an amikacin acetyltransferase gene found on a transferable plasmid of the Serratia marcescens strain NUBL-11663. It catalyzes the transfer of an acetyl group from acetyl coenzyme A onto an amine at the 6'-position of various aminoglycosides.
JZBZ01000026.1_86 # 89195 # 90499 600.0 863.988 Acinetobacter baumannii AbaQ 99.77 ARO:3004574 protein homolog model fluoroquinolone antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AbaQ is an MFS transporter mainly involved in the extrusion of quinolone-type drugs in A. baumannii.
JZBZ01000027.1_236 # 262326 # 262580 100.0 102.064 rsmA 89.09 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
JZBZ01000031.1_2 # 322 # 1200 500.0 566.229 OXA-23 100.0 ARO:3001418 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-23 is a beta-lactamase found in A. baumannii.
JZBZ01000053.1_2 # 751 # 3927 2000.0 2149.4 adeJ 99.91 ARO:3000781 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeJ is a RND efflux protein that acts as the inner membrane transporter of the AdeIJK efflux complex. It has 57% identity with E. coli AcrB.
JZBZ01000053.1_3 # 3927 # 5381 950.0 974.926 adeK 100.0 ARO:3000782 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeK is the outer membrane factor protein in the adeIJK multidrug efflux complex.
JZBZ01000001.1_1 # 257 # 1117 565.0 582.408 AAC(3)-IIe 98.95 ARO:3004621 protein homolog model aminoglycoside antibiotic antibiotic inactivation AAC(3) AAC(3)-IIe is a plasmid-encoded aminoglycoside acetyltransferase in E. coli.
JZBZ01000003.1_39 # 39470 # 40759 700.0 863.218 Acinetobacter baumannii AbaF 99.77 ARO:3004573 protein homolog model phosphonic acid antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Expression of abaF in E. coli resulted in increased resistance to fosfomycin.
JZBZ01000006.1_213 # 242990 # 245704 1500.0 1835.08 Acinetobacter baumannii gyrA conferring resistance to fluoroquinolones 99.78 ARO:3003817 protein variant model S81L fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant gyrA Mutations in the A subunit of DNA gyrase reduce its affinity for fluoroquinolones, thereby conferring resistance.
JZBZ01000054.1_66 # 67727 # 69946 1400.0 1507.27 Acinetobacter baumannii parC conferring resistance to fluoroquinolones 99.86 ARO:3003818 protein variant model S84L, V104I, D105E fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant parC Mutations in Acinetobacter baumannii parC that result in resistance to fluoroquinolones.
JZBZ01000017.1_4 # 2865 # 3488 400.0 427.172 tetR 100.0 ARO:3003479 protein overexpression model tetracycline antibiotic antibiotic target alteration; antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline resistance gene (tetA) promoter operator sites. Mutations arise within tetR results in lower affinity for tetracyclin.
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
JZBZ01000006.1_8 97.943 0.0 basJ VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basJ) acinetobactin biosynthesis protein BasJ [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_9 88.048 2.76E-163 basI VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basI) phosphopantetheinyl transferase component of acinetobactin biosynthesis protein BasI [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_10 97.541 2.87E-180 basH VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basH) non-ribosomal peptide biosynthesis thioesterase BasH [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_11 99.058 0.0 barB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barB) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_12 97.388 0.0 barA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barA) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_14 98.695 0.0 basG VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_15 99.308 0.0 basF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basF) aryl carrier protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_16 98.708 0.0 entE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (entE) non-ribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_17 96.939 0.0 basD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basD) acinetobactin biosynthesis protein BasD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_18 99.083 0.0 basC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basC) acinetobactin biosynthesis protein BasC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_19 68.857 0.0 bauA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauA) TonB-dependent siderophore receptor BauA [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_20 98.758 0.0 bauB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauB) ferric siderophore ABC transporter, periplasmic siderophore-binding protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_21 99.609 0.0 bauE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauE) ferric siderophore ABC transporter, ATP-binding protein BauE [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_22 97.778 0.0 bauC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauC) ferric siderophore ABC transporter, permease protein BauC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_23 99.333 0.0 bauD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauD) ferric siderophore ABC transporter, permease protein BauD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_25 96.893 0.0 basB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basB) non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_26 95.285 0.0 basA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basA) acinetobactin biosynthesis protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_27 97.902 0.0 bauF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauF) siderophore-interacting protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000006.1_196 100.0 0.0 lpxM VF0466 LPS Immune modulation VFC0258 (lpxM) lysophospholipid acyltransferase family protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000008.1_83 97.806 0.0 gspK VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspK) general secretion pathway protein K [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000008.1_85 99.206 1.05E-90 gspI VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspI) general secretion pathway protein I [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000008.1_86 98.913 6.0E-136 gspH VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspH) general secretion pathway protein H [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000008.1_159 60.816 4.42E-101 CBU_1566 VF0696 T4SS secreted effectors Effector delivery system VFC0086 (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] Coxiella burnetii
JZBZ01000009.1_20 63.452 2.47E-88 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JZBZ01000009.1_58 99.378 0.0 adeH VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_59 99.906 0.0 adeG VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_60 99.507 0.0 adeF VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeF) membrane-fusion protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_74 99.316 0.0 gspE2 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_112 98.417 0.0 gspL VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspL) general secretion pathway protein L [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_113 100.0 1.73E-114 gspM VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspM) general secretion pathway protein M [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_157 100.0 9.77E-129 csuA/B VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuA/B) Csu pilus major pilin subunit CsuA/B [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_159 98.256 4.84E-125 csuB VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuB) Csu pilus subunit CsuB [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_160 98.917 0.0 csuC VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_161 99.639 0.0 csuD VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuD) Csu pilus usher protein CsuD [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_162 97.345 0.0 csuE VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuE) Csu pilus tip adhesin CsuE [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_220 98.194 0.0 pgaB VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaB) poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_221 100.0 0.0 pgaC VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_222 99.351 1.02E-111 pgaD VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaD) poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000009.1_329 98.145 0.0 cpaA VF1336 CpaA Exoenzyme VFC0251 CpaA is the best characterized and most abundant effector secreted by several medically relevant Acinetobacter strains; CpaA stability and secretion depend on the membrane-bound chaperone CpaB, which is encoded adjacent to CpaA (cpaA) metalloendopeptidase CpaA [CpaA (VF1336) - Exoenzyme (VFC0251)] [Acinetobacter baumannii BJAB0715] Acinetobacter baumannii
JZBZ01000010.1_1 81.579 1.66E-16 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JZBZ01000010.1_113 99.636 0.0 bfmS VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000010.1_114 100.0 3.98E-173 bfmR VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_23 100.0 0.0 pilF VF1334 TFP Adherence VFC0001 (pilF) type IV pilus biogenesis/stability protein PilW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_45 67.021 6.67E-97 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
JZBZ01000014.1_93 98.714 0.0 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_94 99.454 0.0 lpsB VF0466 LPS Immune modulation VFC0258 (lpsB) glycosyltransferase family 4 protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_98 98.018 0.0 fimV VF1334 TFP Adherence VFC0001 (fimV) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_152 100.0 7.06E-147 gspG VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspG) general secretion pathway protein G [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_153 100.0 0.0 gspF VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspF) general secretion pathway protein F [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_191 99.298 0.0 pilB VF1334 TFP Adherence VFC0001 (pilB) type IV-A pilus assembly ATPase PilB [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_192 100.0 0.0 pilC VF1334 TFP Adherence VFC0001 (pilC) type II secretion system F family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_193 97.902 0.0 gspO/pilD VF1334 TFP Adherence VFC0001 (gspO/pilD) A24 family peptidase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000014.1_240 82.051 1.28E-16 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JZBZ01000015.1_5 99.744 0.0 lpxB VF0466 LPS Immune modulation VFC0258 (lpxB) lipid-A-disaccharide synthase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000018.1_8 99.395 0.0 gspE1 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE1) general secretion pathway protein E [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_7 99.479 0.0 tsaP VF1334 TFP Adherence VFC0001 (tsaP) LysM peptidoglycan-binding domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_58 98.739 4.95E-180 abaR VF0471 Quorom sensing Biofilm VFC0271 (abaR) DNA-binding HTH domain-containing protein [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_60 98.907 4.04E-137 abaI VF0471 Quorom sensing Biofilm VFC0271 (abaI) N-acyl-L-homoserine lactone synthetase [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_98 98.465 0.0 ACICU_RS00500 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00500) phosphomannomutase/phosphoglucomutase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_99 99.408 0.0 galE VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galE) UDP-glucose 4-epimerase GalE [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_100 99.281 0.0 pgi VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pgi) glucose-6-phosphate isomerase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_101 98.81 0.0 ACICU_RS00485 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00485) nucleotide sugar dehydrogenase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_102 96.564 0.0 galU VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galU) UTP--glucose-1-phosphate uridylyltransferase GalU [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_103 76.119 3.76E-111 ACICU_RS00475 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00475) sugar transferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_109 69.88 9.61E-176 cap8E VF0003 Capsule Immune modulation VFC0258 Produced by over 90% of Staphylococcus aureus strains. Two serotypes (5 and 8) predominate among clinical isolates of S. aureus from humans (cap8E) type 8 capsular polysaccharide synthesis protein Cap8E [Capsule (VF0003) - Immune modulation (VFC0258)] [Staphylococcus aureus subsp. aureus MW2] Staphylococcus aureus
JZBZ01000023.1_114 64.793 2.44E-168 tviC VF0101 Vi antigen Immune modulation VFC0258 Vi is abbreviation for virulence; the viaB locus is within Salmonella pathogenicity island SPI-7, which also encodes SopE and a type IVB pilus; The viaB locus encodes genes involved in regulation (tviA), Vi biosynthesis (tviBCDE), export, and retention of the Vi on the bacterial cell surface (vexABCDE); A viaB locus is absent from S. Paratyphi A, and most gastroenteritis-causing serovars including S. Typhimurium (tviC) Vi polysaccharide biosynthesis protein, UDP-GlcNAcA 4-epimerase TviC [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18] Salmonella enterica (serovar typhi)
JZBZ01000023.1_115 82.075 0.0 tviB VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (tviB) Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_116 96.721 0.0 ACICU_RS00405 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00405) polysaccharide biosynthesis/export family protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_117 95.775 1.45E-103 ACICU_RS00400 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00400) low molecular weight phosphotyrosine protein phosphatase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_118 96.566 0.0 ACICU_RS00395 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00395) polysaccharide biosynthesis tyrosine autokinase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000023.1_125 98.615 0.0 plc1 VF0470 Phospholipase C Exotoxin VFC0235 (plc1) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000025.1_2 97.207 0.0 ACICU_RS04580 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04580) TonB-dependent receptor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000025.1_3 96.154 0.0 ACICU_RS04575 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04575) FecR domain-containing protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000025.1_4 98.844 7.76E-127 ACICU_RS04570 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04570) sigma-70 family RNA polymerase sigma factor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000025.1_5 98.986 0.0 ACICU_RS04565 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04565) LysR family transcriptional regulator [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000025.1_34 100.0 0.0 pilT VF1334 TFP Adherence VFC0001 (pilT) type IV pilus twitching motility protein PilT [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000025.1_35 100.0 0.0 pilU VF1334 TFP Adherence VFC0001 (pilU) PilT/PilU family type 4a pilus ATPase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000025.1_64 82.051 1.28E-16 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JZBZ01000026.1_30 61.429 2.0E-131 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JZBZ01000026.1_102 84.661 0.0 katA VF0454 KatA Stress survival VFC0282 (katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58] Neisseria meningitidis
JZBZ01000027.1_2 98.228 0.0 ACICU_RS04580 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04580) TonB-dependent receptor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000027.1_3 99.24 0.0 ACICU_RS04585 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04585) transferrin-binding protein-like solute binding protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000027.1_4 96.721 0.0 ACICU_RS04590 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04590) porin family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000027.1_5 95.425 0.0 ACICU_RS04595 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04595) TonB family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000027.1_6 99.495 1.88E-146 hemO VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (hemO) biliverdin-producing heme oxygenase [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000027.1_7 99.315 5.3E-106 ACICU_RS04605 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04605) YbaN family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000027.1_8 100.0 1.17E-65 ACICU_RS04610 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04610) hypothetical protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000027.1_100 61.0 2.5E-34 ureA VF0050 Urease Stress survival VFC0282 (ureA) urease alpha subunit UreA [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JZBZ01000027.1_105 61.421 8.95E-94 ureG VF0050 Urease Stress survival VFC0282 (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JZBZ01000028.1_56 65.902 9.77E-156 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000028.1_92 89.907 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000038.1_16 99.415 1.2E-126 fimT VF1334 TFP Adherence VFC0001 (fimT) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000038.1_17 99.719 0.0 ompA VF0464 OmpA Immune modulation VFC0258 (ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000040.1_18 100.0 0.0 lpxA VF0466 LPS Immune modulation VFC0258 (lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000040.1_20 99.157 0.0 lpxD VF0466 LPS Immune modulation VFC0258 (lpxD) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000041.1_5 99.63 0.0 plcD VF0469 Phospholipase D Exotoxin VFC0235 (plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_149 95.035 8.96E-89 pilE VF1334 TFP Adherence VFC0001 (pilE) type IV pilin protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_150 94.375 1.66E-103 ACICU_RS16840 VF1334 TFP Adherence VFC0001 (ACICU_RS16840) prepilin-type N-terminal cleavage/methylation domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_151 99.688 0.0 pilY1 VF1334 TFP Adherence VFC0001 (pilY1) VWA domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_152 99.632 0.0 pilX VF1334 TFP Adherence VFC0001 (pilX) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_153 98.799 0.0 pilW VF1334 TFP Adherence VFC0001 (pilW) PilW family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_154 100.0 3.74E-138 pilV VF1334 TFP Adherence VFC0001 (pilV) type IV pilus modification protein PilV [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_155 99.363 1.07E-110 fimU VF1334 TFP Adherence VFC0001 (fimU) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_174 99.861 0.0 pilQ VF1334 TFP Adherence VFC0001 (pilQ) type IV pilus secretin PilQ [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_175 98.857 4.08E-128 pilP VF1334 TFP Adherence VFC0001 (pilP) pilus assembly protein PilP [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_176 99.187 0.0 pilO VF1334 TFP Adherence VFC0001 (pilO) type 4a pilus biogenesis protein PilO [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_177 99.061 2.71E-160 pilN VF1334 TFP Adherence VFC0001 (pilN) PilN domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_178 99.716 0.0 pilM VF1334 TFP Adherence VFC0001 (pilM) pilus assembly protein PilM [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_318 100.0 0.0 lpxC VF0466 LPS Immune modulation VFC0258 (lpxC) UDP-3-O-acyl-N-acetylglucosamine deacetylase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000044.1_360 98.047 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000049.1_17 73.004 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JZBZ01000051.1_10 66.359 1.69E-98 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JZBZ01000052.1_3 99.191 0.0 plc2 VF0470 Phospholipase C Exotoxin VFC0235 (plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000053.1_93 100.0 0.0 pilJ VF1334 TFP Adherence VFC0001 (pilJ) methyl-accepting chemotaxis protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000053.1_94 98.876 1.14E-133 pilI VF1334 TFP Adherence VFC0001 (pilI) chemotaxis protein CheW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000053.1_95 100.0 1.26E-86 pilH VF1334 TFP Adherence VFC0001 (pilH) response regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000053.1_96 100.0 9.66E-94 pilG VF1334 TFP Adherence VFC0001 (pilG) twitching motility response regulator PilG [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000054.1_1 81.579 1.66E-16 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JZBZ01000054.1_5 100.0 0.0 gspD VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspD) general secretion pathway protein D [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000054.1_6 99.281 0.0 gspC VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspC) general secretion pathway protein C [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000054.1_7 100.0 0.0 gspN VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspN) type II secretion system protein N [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000054.1_37 99.701 0.0 pbpG VF0468 PbpG Immune modulation VFC0258 (pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000054.1_39 99.234 0.0 pilS VF1334 TFP Adherence VFC0001 (pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000054.1_40 99.366 0.0 pilR VF1334 TFP Adherence VFC0001 (pilR) sigma-54 dependent transcriptional regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000056.1_39 60.989 2.07E-175 rfbD VF0561 LPS Immune modulation VFC0258 In K. pneumoniae there are nine main O-serotypes. Three of these, O1, O2, and O3, are responsible for almost 80% of all Klebsiella infections.; Compared with other Enterobacteriaceae, such as Escherichia coli 161 defined O serotypes and Shigella flexneri at least 47 O serotypes, Klebsiella has a surprisingly low number of reported O serotypes which promises a more viable alternative for vaccine development compared with K-antigen-based vaccines; The O-antigen biosynthesis enzymes are encoded on the rfb locus. (rfbD) UDP-galactopyranose mutase [LPS (VF0561) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
JZBZ01000002.1_1 78.173 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JZBZ01000003.1_3 100.0 4.65E-120 tssB VF1337 T6SS Effector delivery system VFC0086 (tssB) type VI secretion system contractile sheath small subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_4 100.0 0.0 tssC VF1337 T6SS Effector delivery system VFC0086 (tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_5 100.0 5.53E-126 hcp/tssD VF1337 T6SS Effector delivery system VFC0086 (hcp/tssD) type VI secretion system tube protein Hcp [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_6 100.0 2.59E-116 tssE VF1337 T6SS Effector delivery system VFC0086 (tssE) type VI secretion system baseplate subunit TssE [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_7 99.337 0.0 tssF VF1337 T6SS Effector delivery system VFC0086 (tssF) type VI secretion system baseplate subunit TssF [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_8 99.398 0.0 tssG VF1337 T6SS Effector delivery system VFC0086 (tssG) type VI secretion system baseplate subunit TssG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_10 99.608 0.0 tssM VF1337 T6SS Effector delivery system VFC0086 (tssM) type VI secretion system membrane subunit TssM [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_14 99.664 0.0 clpV/tssH VF1337 T6SS Effector delivery system VFC0086 (clpV/tssH) type VI secretion system ATPase TssH [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_15 100.0 0.0 tssA VF1337 T6SS Effector delivery system VFC0086 (tssA) type VI secretion system protein TssA [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_16 99.559 0.0 tssK VF1337 T6SS Effector delivery system VFC0086 (tssK) type VI secretion system baseplate subunit TssK [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_17 99.627 0.0 tssL VF1337 T6SS Effector delivery system VFC0086 (tssL) type IVB secretion system protein TssL [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JZBZ01000003.1_19 100.0 0.0 tagX VF1337 T6SS Effector delivery system VFC0086 (tagX) type VI-associated gene X, peptidoglycan hydrolase [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii