2. PATHOGENS
Basic Information
Accession number
GCA_001028315.1
Release date
2015-06-16
Organism
Acinetobacter baumannii MRSN 58
Species name
Acinetobacter baumannii
Assembly level
Scaffold
Assembly name
gdodcwi05 v01
Assembly submitter
J. Craig Venter Institute
Assembly Type
haploid
Genome size
4.0 Mb
GC percent
39.0
Contig count
40
Collection date
2010-06
Sample location
USA
Host
Homo sapiens
Isolation source
wound
Isolate type
-
Strain
MRSN 58
Isolate
-
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
JPHW01000008.1_106 # 122712 # 123500 200.0 374.015 ANT(3'')-IIc 69.77 ARO:3004091 protein homolog model aminoglycoside antibiotic antibiotic inactivation ANT(3'') ANT(3'')-IIc is a aminoglycoside nucleotidyltransferase identified in Acinetobacter spp. via horizontal gene transfer mechanisms.
JPHW01000029.1_278 # 274759 # 275088 175.0 209.92 abeS 100.0 ARO:3000768 protein homolog model macrolide antibiotic; aminocoumarin antibiotic antibiotic efflux small multidrug resistance (SMR) antibiotic efflux pump AbeS in an efflux pump of the SMR family of transporters found in Acinetobacter baumannii.
JPHW01000029.1_283 # 278397 # 279428 650.0 692.575 adeL 99.7 ARO:3000620 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeL is a regulator of AdeFGH in Acinetobacter baumannii. AdeL mutations are associated with AdeFGH overexpression and multidrug resistance.
JPHW01000029.1_284 # 279626 # 280846 800.0 818.15 adeG 100.0 ARO:3000778 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeG is the inner membrane transporter of the AdeFGH multidrug efflux complex.
JPHW01000029.1_285 # 280853 # 284032 750.0 2139.38 adeF 100.0 ARO:3000777 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH.
JPHW01000029.1_286 # 284045 # 285493 900.0 962.6 adeH 99.79 ARO:3000779 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeH is the outer membrane channel protein of the AdeFGH multidrug efflux complex.
JPHW01000004.1_1 # 109 # 1260 700.0 786.178 ADC-191 100.0 ARO:3006360 protein homolog model cephalosporin antibiotic inactivation ADC beta-lactamases pending classification for carbapenemase activity ADC-191 is a ADC beta-lactamase.
JPHW01000034.1_7 # 5513 # 6046 300.0 313.153 AAC(3)-Ia 98.7 ARO:3002528 protein homolog model aminoglycoside antibiotic antibiotic inactivation AAC(3) AAC(3)-Ia is an aminoglycoside acetyltransferase encoded by plasmids, transposons, integrons in S. marcescens, E. coli, Acinetobacter baumannii, Klebsiella pneumoniae, Klebsiella oxytoca, P. aeruginosa, Salmonella typhimurium and Proteus mirabilis.
JPHW01000034.1_9 # 7102 # 7878 450.0 513.072 ANT(3'')-IIa 99.23 ARO:3004089 protein homolog model aminoglycoside antibiotic antibiotic inactivation ANT(3'') ANT(3'')-IIa is a aminoglycoside nucleotidyltransferase identified in Acinetobacter spp. via horizontal gene transfer mechanisms.
JPHW01000034.1_10 # 8042 # 8389 190.0 219.55 qacEdelta1 100.0 ARO:3005010 protein homolog model disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump QacEdelta1 is a resistance gene conferring resistance to antiseptics. It is different from QacE only at the 3'-terminus.
JPHW01000034.1_11 # 8383 # 9222 500.0 553.132 sul1 100.0 ARO:3000410 protein homolog model sulfonamide antibiotic antibiotic target replacement sulfonamide resistant sul Sul1 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria. It is linked to other resistance genes of class 1 integrons.
JPHW01000030.1_5 # 4028 # 5425 850.0 932.169 adeC 97.2 ARO:3003811 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeC is the outer membrane factor of the AdeABC multidrug efflux complex. It can be replaced by other outer membrane channels, and is not essential for antibiotic resistance.
JPHW01000030.1_6 # 5502 # 8612 2000.0 2082.37 adeB 99.52 ARO:3000775 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeB is the multidrug transporter of the adeABC efflux system.
JPHW01000030.1_7 # 8609 # 9799 750.0 797.349 adeA 98.99 ARO:3000774 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeA is the membrane fusion protein of the multidrug efflux complex AdeABC.
JPHW01000030.1_8 # 9945 # 10688 480.0 508.064 adeR 100.0 ARO:3000553 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeR is a positive regulator of AdeABC efflux system. AdeR inactivation leads to susceptibility to aminoglycoside antibiotics.
JPHW01000030.1_9 # 10720 # 11805 700.0 734.947 adeS 99.72 ARO:3000549 protein homolog model glycylcycline; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeS is a sensor kinase in the AdeRS regulatory system of AdeABC. It is essential for AdeABC expression.
JPHW01000030.1_58 # 64084 # 64557 300.0 321.627 dfrA1 99.36 ARO:3002854 protein homolog model diaminopyrimidine antibiotic antibiotic target replacement trimethoprim resistant dihydrofolate reductase dfr dfrA1 is an integron-encoded dihydrofolate reductase.
JPHW01000030.1_59 # 64652 # 65176 300.0 365.925 SAT-2 100.0 ARO:3002895 protein homolog model nucleoside antibiotic antibiotic inactivation streptothricin acetyltransferase (SAT) SAT-2 is a plasmid-mediated streptothricin acetyltransferase, which confers resistance to streptothricin, a nucleoside antibiotic. Originally described from an E. coli plasmid sequence by Heim et al., 1989.
JPHW01000019.1_31 # 31383 # 32672 700.0 860.907 Acinetobacter baumannii AbaF 99.77 ARO:3004573 protein homolog model phosphonic acid antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Expression of abaF in E. coli resulted in increased resistance to fosfomycin.
JPHW01000019.1_266 # 281275 # 282099 500.0 567.77 OXA-69 100.0 ARO:3001617 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-69 is a beta-lactamase found in A. baumannii.
JPHW01000022.1_109 # 124940 # 126286 850.0 886.33 abeM 99.55 ARO:3000753 protein homolog model fluoroquinolone antibiotic; disinfecting agents and antiseptics antibiotic efflux multidrug and toxic compound extrusion (MATE) transporter AbeM is an multidrug efflux pump found in Acinetobacter baumannii.
JPHW01000022.1_144 # 166654 # 167754 700.0 743.421 LpsB 98.09 ARO:3005051 protein homolog model peptide antibiotic reduced permeability to antibiotic Intrinsic peptide antibiotic resistant Lps LpsB is involved in lipopolysaccharide synthesis. It confers intrinsic resistance to colistin and other peptide antibiotics.
JPHW01000011.1_12 # 10445 # 10699 100.0 102.064 rsmA 89.09 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
JPHW01000006.1_45 # 40330 # 41634 600.0 864.759 Acinetobacter baumannii AbaQ 100.0 ARO:3004574 protein homolog model fluoroquinolone antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AbaQ is an MFS transporter mainly involved in the extrusion of quinolone-type drugs in A. baumannii.
JPHW01000009.1_121 # 123615 # 124268 420.0 448.743 adeN 99.08 ARO:3000559 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeN is a repressor of AdeIJK, a RND-type efflux pump in Acinetobacter baumannii. Its inactivation increases expression of AdeJ.
JPHW01000009.1_172 # 178336 # 179814 600.0 969.148 Acinetobacter baumannii AmvA 100.0 ARO:3004577 protein homolog model macrolide antibiotic; disinfecting agents and antiseptics antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump AmvA has 14 alpha-helical transmembrane segments, qualifying it as a member of the DHA2 transporter family of the major facilitator superfamily (MFS). When AmvA was expressed in E. coli, the cells had at least four-fold decreased susceptibility to erythromycin, acridine orange, acriflavine, deoxycholate and methyl viologen. AmvA from the AC0037 strain of A. baumannii was tested.
JPHW01000016.1_2 # 347 # 1552 700.0 786.563 tet(B) 99.5 ARO:3000166 protein homolog model tetracycline antibiotic antibiotic efflux major facilitator superfamily (MFS) antibiotic efflux pump Tet(B) is a tetracycline efflux protein expressed in many Gram-negative bacteria. It confers resistance to tetracycline, doxycycline, and minocycline, but not tigecycline.
JPHW01000005.1_1 # 134 # 955 500.0 565.459 OXA-23 100.0 ARO:3001418 protein homolog model carbapenem; cephalosporin; penam antibiotic inactivation OXA beta-lactamase OXA-23 is a beta-lactamase found in A. baumannii.
JPHW01000020.1_3 # 1158 # 2024 500.0 529.635 sul2 100.0 ARO:3000412 protein homolog model sulfonamide antibiotic antibiotic target replacement sulfonamide resistant sul Sul2 is a sulfonamide resistant dihydropteroate synthase of Gram-negative bacteria, usually found on small plasmids.
JPHW01000033.1_40 # 44923 # 46173 800.0 832.787 adeI 100.0 ARO:3000780 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeI is the membrane fusion protein of the AdeIJK multidrug efflux complex.
JPHW01000033.1_41 # 46186 # 49362 2000.0 2149.4 adeJ 99.91 ARO:3000781 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeJ is a RND efflux protein that acts as the inner membrane transporter of the AdeIJK efflux complex. It has 57% identity with E. coli AcrB.
JPHW01000033.1_42 # 49362 # 50816 950.0 974.926 adeK 100.0 ARO:3000782 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; lincosamide antibiotic; carbapenem; cephalosporin; tetracycline antibiotic; rifamycin antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic; penem antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeK is the outer membrane factor protein in the adeIJK multidrug efflux complex.
JPHW01000027.1_14 # 12910 # 15624 1500.0 1836.62 Acinetobacter baumannii gyrA conferring resistance to fluoroquinolones 99.89 ARO:3003817 protein variant model S81L fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant gyrA Mutations in the A subunit of DNA gyrase reduce its affinity for fluoroquinolones, thereby conferring resistance.
JPHW01000010.1_20 # 18942 # 21161 1400.0 1504.96 Acinetobacter baumannii parC conferring resistance to fluoroquinolones 99.73 ARO:3003818 protein variant model V104I, D105E fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant parC Mutations in Acinetobacter baumannii parC that result in resistance to fluoroquinolones.
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
JPHW01000008.1_27 97.23 0.0 plc1 VF0470 Phospholipase C Exotoxin VFC0235 (plc1) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_34 91.621 0.0 ACICU_RS00395 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00395) polysaccharide biosynthesis tyrosine autokinase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_35 92.254 8.93E-101 ACICU_RS00400 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00400) low molecular weight phosphotyrosine protein phosphatase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_36 91.53 0.0 ACICU_RS00405 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00405) polysaccharide biosynthesis/export family protein [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_37 79.717 0.0 tviB VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (tviB) Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_38 68.713 5.88E-175 tviC VF0101 Vi antigen Immune modulation VFC0258 Vi is abbreviation for virulence; the viaB locus is within Salmonella pathogenicity island SPI-7, which also encodes SopE and a type IVB pilus; The viaB locus encodes genes involved in regulation (tviA), Vi biosynthesis (tviBCDE), export, and retention of the Vi on the bacterial cell surface (vexABCDE); A viaB locus is absent from S. Paratyphi A, and most gastroenteritis-causing serovars including S. Typhimurium (tviC) Vi polysaccharide biosynthesis protein, UDP-GlcNAcA 4-epimerase TviC [Vi antigen (VF0101) - Immune modulation (VFC0258)] [Salmonella enterica subsp. enterica serovar Typhi str. CT18] Salmonella enterica (serovar typhi)
JPHW01000008.1_44 60.804 4.69E-92 ACICU_RS00475 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00475) sugar transferase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_48 95.876 0.0 galU VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (galU) UTP--glucose-1-phosphate uridylyltransferase GalU [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_49 92.619 0.0 ACICU_RS00485 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00485) nucleotide sugar dehydrogenase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_50 93.153 0.0 pgi VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (pgi) glucose-6-phosphate isomerase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_51 97.807 0.0 ACICU_RS00500 VF0465 Capsule Immune modulation VFC0258 A. baumannii pan-genome was shown to include a highly diverse repertoire of gene sequences. In particular, capsule gene cluster is highly variable. The cluster at the K locus often contains either capsule export genes (wza, wzb, and wzc) or genes for simple sugar synthesis (galU, ugd, gpi, gne1, and pgm), which flank a central variable region that would be required for the synthesis of a specific monosaccharide. (ACICU_RS00500) phosphomannomutase/phosphoglucomutase [Capsule (VF0465) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_86 99.454 1.79E-137 abaI VF0471 Quorom sensing Biofilm VFC0271 (abaI) N-acyl-L-homoserine lactone synthetase [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_88 98.739 4.95E-180 abaR VF0471 Quorom sensing Biofilm VFC0271 (abaR) DNA-binding HTH domain-containing protein [Quorom sensing (VF0471) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000008.1_138 98.958 0.0 tsaP VF1334 TFP Adherence VFC0001 (tsaP) LysM peptidoglycan-binding domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_149 94.326 4.3E-88 pilE VF1334 TFP Adherence VFC0001 (pilE) type IV pilin protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_150 94.375 3.67E-103 ACICU_RS16840 VF1334 TFP Adherence VFC0001 (ACICU_RS16840) prepilin-type N-terminal cleavage/methylation domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_151 97.741 0.0 pilY1 VF1334 TFP Adherence VFC0001 (pilY1) VWA domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_152 99.632 0.0 pilX VF1334 TFP Adherence VFC0001 (pilX) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_153 98.799 0.0 pilW VF1334 TFP Adherence VFC0001 (pilW) PilW family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_154 100.0 3.74E-138 pilV VF1334 TFP Adherence VFC0001 (pilV) type IV pilus modification protein PilV [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_155 98.089 4.55E-109 fimU VF1334 TFP Adherence VFC0001 (fimU) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_174 99.861 0.0 pilQ VF1334 TFP Adherence VFC0001 (pilQ) type IV pilus secretin PilQ [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_175 98.286 6.07E-126 pilP VF1334 TFP Adherence VFC0001 (pilP) pilus assembly protein PilP [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_176 99.187 0.0 pilO VF1334 TFP Adherence VFC0001 (pilO) type 4a pilus biogenesis protein PilO [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_177 99.061 2.16E-160 pilN VF1334 TFP Adherence VFC0001 (pilN) PilN domain-containing protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_178 99.432 0.0 pilM VF1334 TFP Adherence VFC0001 (pilM) pilus assembly protein PilM [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_307 100.0 0.0 lpxC VF0466 LPS Immune modulation VFC0258 (lpxC) UDP-3-O-acyl-N-acetylglucosamine deacetylase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000007.1_343 99.008 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_125 99.351 4.29E-112 pgaD VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaD) poly-beta-1,6-N-acetyl-D-glucosamine biosynthesis protein PgaD [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_126 99.759 0.0 pgaC VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaC) poly-beta-1,6 N-acetyl-D-glucosamine synthase [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_127 98.194 0.0 pgaB VF0472 PNAG Biofilm VFC0271 PNAG is produced by the Pga machinery consisting of PgaABCD proteins. Pga complex probably spans the inner and outer bacterial membrane. PgaC and PgaD form an inner membrane-intergrated complex. PgaC is the cataytic glycosyltransferase containing 4-5 predicted transmembrane helices (TMHs). PgaD probably contains two TMHs with a short periplasmic loop and small cytosolic C terminus. PgaA is an outer membrane porin and might associate with PgaB, a periplasmic lipoprotein that is probably anchored to the outer membrane. PgaB deacetylates a small fraction of the polymer's NAG units. (pgaB) poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB [PNAG (VF0472) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_192 97.935 0.0 csuE VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuE) Csu pilus tip adhesin CsuE [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_193 99.159 0.0 csuD VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuD) Csu pilus usher protein CsuD [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_194 98.917 0.0 csuC VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuC) Csu pilus chaperone protein CsuC [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_195 96.512 1.11E-123 csuB VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuB) Csu pilus subunit CsuB [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_197 100.0 9.77E-129 csuA/B VF0461 Csu fimbriae Biofilm VFC0271 Chaperone-usher pathway assembled fimbriae (csuA/B) Csu pilus major pilin subunit CsuA/B [Csu fimbriae (VF0461) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_237 100.0 1.73E-114 gspM VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspM) general secretion pathway protein M [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_238 99.208 0.0 gspL VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspL) general secretion pathway protein L [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_270 99.145 0.0 gspE2 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE2) putative secretion pathway ATPase [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_284 100.0 0.0 adeF VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeF) membrane-fusion protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_285 99.811 0.0 adeG VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeG) cation/multidrug efflux pump [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000029.1_286 99.793 0.0 adeH VF0504 AdeFGH efflux pump Biofilm VFC0271 Belongs to resistance-nodulation-cell division (RND)-type efflux system; RND efflux systems, composed of an inner membrane protein (RND pump) linked by a periplasmic adaptor protein (PAP) to an outer membrane factor (OMF), can extrude a wide range of substrates often unrelated in structure; To date, three Acinetobacter drug efflux (Ade) RND systems, AdeABC, AdeFGH, and AdeIJK, have been characterized in A. baumannii (adeH) outer membrane protein [AdeFGH efflux pump (VF0504) - Biofilm (VFC0271)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000035.1_94 62.944 1.11E-87 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JPHW01000027.1_54 73.004 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JPHW01000004.1_7 98.201 0.0 basJ VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basJ) acinetobactin biosynthesis protein BasJ [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_8 94.422 8.47E-177 basI VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basI) phosphopantetheinyl transferase component of acinetobactin biosynthesis protein BasI [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_9 98.77 0.0 basH VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basH) non-ribosomal peptide biosynthesis thioesterase BasH [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_10 97.74 0.0 barB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barB) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_11 96.269 0.0 barA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (barA) siderophore efflux system of the ABC superfamily [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_13 99.478 0.0 basG VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basG) acinetobactin biosynthesis protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_14 99.654 0.0 basF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basF) aryl carrier protein BasF [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_15 98.155 0.0 entE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (entE) non-ribosomal peptide synthetase adenylate-forming enzyme of acinetobactin synthesis [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_16 96.02 0.0 basD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basD) acinetobactin biosynthesis protein BasD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_17 99.771 0.0 basC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basC) acinetobactin biosynthesis protein BasC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_18 68.857 0.0 bauA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauA) TonB-dependent siderophore receptor BauA [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_19 99.379 0.0 bauB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauB) ferric siderophore ABC transporter, periplasmic siderophore-binding protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_20 99.609 0.0 bauE VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauE) ferric siderophore ABC transporter, ATP-binding protein BauE [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_21 98.095 0.0 bauC VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauC) ferric siderophore ABC transporter, permease protein BauC [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_22 99.333 0.0 bauD VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauD) ferric siderophore ABC transporter, permease protein BauD [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_25 95.858 0.0 basB VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basB) non-ribosomal peptide synthetase with condensation and peptidyl carrier protein domains [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_26 95.285 0.0 basA VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (basA) acinetobactin biosynthesis protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_27 98.252 0.0 bauF VF0467 Acinetobactin Nutritional/Metabolic factor VFC0272 (bauF) siderophore-interacting protein [Acinetobactin (VF0467) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000004.1_211 99.694 0.0 lpxM VF0466 LPS Immune modulation VFC0258 (lpxM) lysophospholipid acyltransferase family protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000034.1_39 100.0 0.0 pilR VF1334 TFP Adherence VFC0001 (pilR) sigma-54 dependent transcriptional regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000034.1_40 100.0 0.0 pilS VF1334 TFP Adherence VFC0001 (pilS) PAS domain-containing sensor histidine kinase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000034.1_42 99.701 0.0 pbpG VF0468 PbpG Immune modulation VFC0258 (pbpG) D-alanyl-D-alanine endopeptidase PBP7/8 [PbpG (VF0468) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000034.1_72 99.595 0.0 gspN VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspN) type II secretion system protein N [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000034.1_73 99.281 0.0 gspC VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspC) general secretion pathway protein C [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000034.1_74 100.0 0.0 gspD VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspD) general secretion pathway protein D [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000034.1_78 78.205 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JPHW01000019.1_2 99.686 0.0 tssM VF1337 T6SS Effector delivery system VFC0086 (tssM) type VI secretion system membrane subunit TssM [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_6 99.664 0.0 clpV/tssH VF1337 T6SS Effector delivery system VFC0086 (clpV/tssH) type VI secretion system ATPase TssH [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_7 100.0 0.0 tssA VF1337 T6SS Effector delivery system VFC0086 (tssA) type VI secretion system protein TssA [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_8 99.559 0.0 tssK VF1337 T6SS Effector delivery system VFC0086 (tssK) type VI secretion system baseplate subunit TssK [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_9 99.627 0.0 tssL VF1337 T6SS Effector delivery system VFC0086 (tssL) type IVB secretion system protein TssL [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_11 100.0 0.0 tagX VF1337 T6SS Effector delivery system VFC0086 (tagX) type VI-associated gene X, peptidoglycan hydrolase [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_241 60.816 4.42E-101 CBU_1566 VF0696 T4SS secreted effectors Effector delivery system VFC0086 (CBU_1566) Coxiella Dot/Icm type IVB secretion system translocated effector [T4SS secreted effectors (VF0696) - Effector delivery system (VFC0086)] [Coxiella burnetii RSA 493] Coxiella burnetii
JPHW01000019.1_314 100.0 3.61E-137 gspH VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspH) general secretion pathway protein H [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_315 99.206 4.39E-90 gspI VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspI) general secretion pathway protein I [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_317 99.06 0.0 gspK VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspK) general secretion pathway protein K [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000019.1_401 99.229 0.0 lpxB VF0466 LPS Immune modulation VFC0258 (lpxB) lipid-A-disaccharide synthase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_1 78.173 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JPHW01000022.1_47 97.902 0.0 gspO/pilD VF1334 TFP Adherence VFC0001 (gspO/pilD) A24 family peptidase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_48 100.0 0.0 pilC VF1334 TFP Adherence VFC0001 (pilC) type II secretion system F family protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_49 99.649 0.0 pilB VF1334 TFP Adherence VFC0001 (pilB) type IV-A pilus assembly ATPase PilB [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_85 99.751 0.0 gspF VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspF) general secretion pathway protein F [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_86 98.964 3.47E-145 gspG VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspG) general secretion pathway protein G [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_140 96.916 0.0 fimV VF1334 TFP Adherence VFC0001 (fimV) hypothetical protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_144 99.18 0.0 lpsB VF0466 LPS Immune modulation VFC0258 (lpsB) glycosyltransferase family 4 protein [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_145 99.035 0.0 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000022.1_191 67.021 6.67E-97 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
JPHW01000022.1_213 98.837 0.0 pilF VF1334 TFP Adherence VFC0001 (pilF) type IV pilus biogenesis/stability protein PilW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000031.1_91 99.798 0.0 gspE1 VF1335 T2SS Effector delivery system VFC0086 Although the T2SS machinery is conserved across Acinetobacter spp., the effector repertoire is diverse and varies from strain to strain;Secretion of type II effectors, CpaA and LipA, require specific membrane-associated chaperones, CpaB and LipB (gspE1) general secretion pathway protein E [T2SS (VF1335) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000024.1_23 66.359 1.69E-98 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JPHW01000024.1_65 100.0 3.98E-173 bfmR VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmR) biofilm-controlling response regulator [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000024.1_66 99.636 0.0 bfmS VF0463 BfmRS Regulation VFC0301 Two-component system: BfmS sensor kinase acts as a BfmR phosphatase to negatively regulate BfmR activity in certain conditions (bfmS) signal transduction histidine kinase [BfmRS (VF0463) - Regulation (VFC0301)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000024.1_179 78.205 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JPHW01000017.1_13 97.973 0.0 ACICU_RS04565 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04565) LysR family transcriptional regulator [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_14 98.266 4.12E-126 ACICU_RS04570 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04570) sigma-70 family RNA polymerase sigma factor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_15 97.633 0.0 ACICU_RS04575 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04575) FecR domain-containing protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_16 97.679 0.0 ACICU_RS04580 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04580) TonB-dependent receptor [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_17 99.24 0.0 ACICU_RS04585 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04585) transferrin-binding protein-like solute binding protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_18 96.311 0.0 ACICU_RS04590 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04590) porin family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_19 93.137 0.0 ACICU_RS04595 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04595) TonB family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_20 99.495 1.88E-146 hemO VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (hemO) biliverdin-producing heme oxygenase [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_21 100.0 1.2E-106 ACICU_RS04605 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04605) YbaN family protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_22 100.0 1.17E-65 ACICU_RS04610 VF0636 HemO cluster Nutritional/Metabolic factor VFC0272 (ACICU_RS04610) hypothetical protein [HemO cluster (VF0636) - Nutritional/Metabolic factor (VFC0272)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000017.1_115 61.0 2.5E-34 ureA VF0050 Urease Stress survival VFC0282 (ureA) urease alpha subunit UreA [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JPHW01000017.1_120 61.421 8.95E-94 ureG VF0050 Urease Stress survival VFC0282 (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JPHW01000032.1_14 72.727 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_130 65.902 3.81E-156 lpxL VF0466 LPS Immune modulation VFC0258 (lpxL) lauroyl acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_140 91.775 0.0 vgrG/tssI VF1337 T6SS Effector delivery system VFC0086 (vgrG/tssI) type VI secretion system tip protein VgrG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_175 100.0 4.65E-120 tssB VF1337 T6SS Effector delivery system VFC0086 (tssB) type VI secretion system contractile sheath small subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_176 100.0 2.4E-69 tssC VF1337 T6SS Effector delivery system VFC0086 (tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_177 100.0 0.0 tssC VF1337 T6SS Effector delivery system VFC0086 (tssC) type VI secretion system contractile sheath large subunit [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_178 100.0 5.53E-126 hcp/tssD VF1337 T6SS Effector delivery system VFC0086 (hcp/tssD) type VI secretion system tube protein Hcp [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_179 100.0 2.59E-116 tssE VF1337 T6SS Effector delivery system VFC0086 (tssE) type VI secretion system baseplate subunit TssE [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_180 99.337 0.0 tssF VF1337 T6SS Effector delivery system VFC0086 (tssF) type VI secretion system baseplate subunit TssF [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000011.1_181 100.0 2.65E-154 tssG VF1337 T6SS Effector delivery system VFC0086 (tssG) type VI secretion system baseplate subunit TssG [T6SS (VF1337) - Effector delivery system (VFC0086)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000009.1_30 61.429 2.0E-131 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JPHW01000009.1_107 100.0 0.0 lpxA VF0466 LPS Immune modulation VFC0258 (lpxA) acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000009.1_109 99.719 0.0 lpxD VF0466 LPS Immune modulation VFC0258 (lpxD) UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase [LPS (VF0466) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000009.1_169 98.922 0.0 plc2 VF0470 Phospholipase C Exotoxin VFC0235 (plc2) phospholipase C [Phospholipase C (VF0470) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000013.1_5 99.261 0.0 plcD VF0469 Phospholipase D Exotoxin VFC0235 (plcD) phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase [Phospholipase D (VF0469) - Exotoxin (VFC0235)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000026.1_1 78.173 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JPHW01000026.1_28 99.731 0.0 pilU VF1334 TFP Adherence VFC0001 (pilU) PilT/PilU family type 4a pilus ATPase [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000026.1_29 99.71 0.0 pilT VF1334 TFP Adherence VFC0001 (pilT) type IV pilus twitching motility protein PilT [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000033.1_168 100.0 0.0 pilJ VF1334 TFP Adherence VFC0001 (pilJ) methyl-accepting chemotaxis protein [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000033.1_169 98.876 1.14E-133 pilI VF1334 TFP Adherence VFC0001 (pilI) chemotaxis protein CheW [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000033.1_170 100.0 1.26E-86 pilH VF1334 TFP Adherence VFC0001 (pilH) response regulator [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000033.1_171 100.0 9.66E-94 pilG VF1334 TFP Adherence VFC0001 (pilG) twitching motility response regulator PilG [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000033.1_197 94.101 0.0 ompA VF0464 OmpA Immune modulation VFC0258 (ompA) outer membrane protein OmpA [OmpA (VF0464) - Immune modulation (VFC0258)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii
JPHW01000033.1_198 99.415 1.2E-126 fimT VF1334 TFP Adherence VFC0001 (fimT) GspH/FimT family pseudopilin [TFP (VF1334) - Adherence (VFC0001)] [Acinetobacter baumannii ACICU] Acinetobacter baumannii