2. PATHOGENS
Basic Information
Accession number
GCA_001188135.2
Release date
2018-01-19
Organism
Vibrio parahaemolyticus
Species name
Vibrio parahaemolyticus
Assembly level
Contig
Assembly name
ASM118813v2
Assembly submitter
University of Maryland School of Medicine Institute for Genome Sciences (IGS) - sequencing center
Assembly Type
haploid
Genome size
5.2 Mb
GC percent
45.5
Contig count
4
Collection date
1998
Sample location
USA: LA
Host
Environment
Isolation source
environmental
Isolate type
Environment
Strain
FDAARGOS_52
Isolate
Not Applicable
ARG List
ORF_ID Pass_Bitscore Best_Hit_Bitscore Best_Hit_ARO Best_Identities ARO Model_type SNPs_in_Best_Hit_ARO Other_SNPs Drug class Resistance mechanism AMR gene family Description
JWSR02000001.1_171 # 205389 # 205586 100.0 102.064 rsmA 90.91 ARO:3005069 protein homolog model fluoroquinolone antibiotic; diaminopyrimidine antibiotic; phenicol antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump rsmA is a gene that regulates virulence of Pseudomonas aeruginosa. However, its negative effect on MexEF-OprN overexpression has been noted to confer resistance to various antibiotics. It's Escherichia coli homolog is csrA.
JWSR02000001.1_442 # 515263 # 515964 50.0 51.9878 vanY gene in vanG cluster 23.27 ARO:3002959 protein homolog model glycopeptide antibiotic antibiotic target alteration vanY; glycopeptide resistance gene cluster Also known as vanYG, is a vanY variant found in the vanG gene cluster.
JWSR02000001.1_1583 # 1764530 # 1765483 400.0 536.184 TxR 86.29 ARO:3005008 protein homolog model tetracycline antibiotic antibiotic efflux ATP-binding cassette (ABC) antibiotic efflux pump TxR is a putative transcription regulator that plays a role in conferring tetracycline resistance. It is required for proper functioning of Tet35.
JWSR02000001.1_1585 # 1768138 # 1769739 710.0 723.005 tet(35) 95.66 ARO:3000481 protein homolog model tetracycline antibiotic antibiotic efflux ATP-binding cassette (ABC) antibiotic efflux pump Tet35 is a tetracycline efflux pump found in the Gram-negative Vibrio and Stenotrophomonas. It is unrelated to other tet resistance genes.
JWSR02000002.1_174 # 216980 # 217612 400.0 418.313 CRP 95.24 ARO:3000518 protein homolog model macrolide antibiotic; fluoroquinolone antibiotic; penam antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump CRP is a global regulator that represses MdtEF multidrug efflux pump expression.
JWSR02000002.1_230 # 273696 # 274781 175.0 184.111 vanT gene in vanG cluster 33.24 ARO:3002972 protein homolog model glycopeptide antibiotic antibiotic target alteration glycopeptide resistance gene cluster; vanT Also known as vanTG, is a vanT variant found in the vanG gene cluster.
JWSR02000004.1_652 # 718222 # 721374 750.0 795.808 adeF 42.09 ARO:3000777 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH.
JWSR02000004.1_1335 # 1500556 # 1501488 500.0 636.336 CARB-21 99.35 ARO:3003176 protein homolog model penam antibiotic inactivation CARB beta-lactamase CARB-21 is a beta-lactamase. Name originally from the historical Lahey list of beta-lactamases, some of which did not include sequence data.
JWSR02000004.1_1341 # 1506323 # 1509463 750.0 827.009 adeF 43.92 ARO:3000777 protein homolog model fluoroquinolone antibiotic; tetracycline antibiotic antibiotic efflux resistance-nodulation-cell division (RND) antibiotic efflux pump AdeF is the membrane fusion protein of the multidrug efflux complex AdeFGH.
JWSR02000001.1_2218 # 2494531 # 2496324 500.0 524.628 Haemophilus influenzae PBP3 conferring resistance to beta-lactam antibiotics 46.7 ARO:3004446 protein variant model S385T cephalosporin; cephamycin; penam antibiotic target alteration Penicillin-binding protein mutations conferring resistance to beta-lactam antibiotics PBP3 is a penicillin-binding protein and beta-lactam resistance enzyme encoded by the ftsI gene in Haemophilus influenzae. Mutations in ftsI confer resistance to beta-lactam antibiotics.
JWSR02000001.1_2238 # 2515292 # 2517172 1000.0 1060.83 Escherichia coli parE conferring resistance to fluoroquinolones 78.98 ARO:3003316 protein variant model D476N fluoroquinolone antibiotic antibiotic target alteration fluoroquinolone resistant parE Point mutation in Escherichia coli parE resulting in fluoroquinolones resistance.
VF List
Query_id %Identity E-value Related genes VF ID Virulence factor VFcategory VFcategoryID Characteristics Description Strain
JWSR02000001.1_14 61.997 0.0 mshH VF0515 MSHA pili Adherence VFC0001 (mshH) MSHA biogenesis protein MshH [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_18 68.271 0.0 mshL VF0515 MSHA pili Adherence VFC0001 (mshL) MSHA biogenesis protein MshL [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_19 61.922 9.28E-131 mshM VF0515 MSHA pili Adherence VFC0001 (mshM) MSHA biogenesis protein MshM [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_21 77.583 0.0 mshE VF0515 MSHA pili Adherence VFC0001 (mshE) MSHA biogenesis protein MshE [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_22 71.253 0.0 mshG VF0515 MSHA pili Adherence VFC0001 (mshG) MSHA biogenesis protein MshG [MSHA pili (VF0515) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_106 74.481 0.0 tapT VF0475 Tap type IV pili Adherence VFC0001 Polar; similar to the P. aeruginosa Pil system; constitutively expressed (tapT) twitching ATPase [Tap type IV pili (VF0475) - Adherence (VFC0001)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
JWSR02000001.1_140 64.398 3.13E-91 algU VF0091 Alginate Biofilm VFC0271 Alginate production is frequently referred to as mucoidy because colonies producing alginate have a wet glistening (mucoid) appearance, which is very different from that of colonies not producing alginate; most of the alginate biosynthetic genes are clustered in the algD operon; Alginate production is highly regulated. Regulatory genes are located in two areas far removed from the biosynthetic genes, with one exception algC (algU) alginate biosynthesis protein AlgZ/FimS [Alginate (VF0091) - Biofilm (VFC0271)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JWSR02000001.1_164 75.949 9.28E-171 rpoS VF0112 RpoS Regulation VFC0301 (rpoS) RNA polymerase sigma factor RpoS [RpoS (VF0112) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
JWSR02000001.1_171 76.271 2.22E-30 csrA VF0261 CsrA Regulation VFC0301 Belongs to a highly conserved family of global regulators that typically control stationary phase traits post-transcriptionally (csrA) carbon storage regulator CsrA [CsrA (VF0261) - Regulation (VFC0301)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JWSR02000001.1_180 88.889 3.2E-118 luxS VF0406 AI-2 Biofilm VFC0271 AI-2 is produced and detected by a wide variety of bacteria and is presumed to facilitate interspecies communications. (luxS) S-ribosylhomocysteinase [AI-2 (VF0406) - Biofilm (VFC0271)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_191 72.569 3.64E-155 pilD/vcpD VF0609 ChiRP Adherence VFC0001 Also known as PilA pilus (pilD/vcpD) A24 family peptidase [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio vulnificus
JWSR02000001.1_192 74.321 0.0 pilC VF0609 ChiRP Adherence VFC0001 Also known as PilA pilus (pilC) type II secretion system F family protein [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio vulnificus
JWSR02000001.1_193 74.021 0.0 pilB VF0609 ChiRP Adherence VFC0001 Also known as PilA pilus (pilB) type IV-A pilus assembly ATPase PilB [ChiRP (VF0609) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio vulnificus
JWSR02000001.1_248 74.504 2.46E-167 ompU VF0514 OmpU Adherence VFC0001 Conserved major outer membrane porin, widely present in pathogenic vibrio (ompU) outer membrane protein OmpU [OmpU (VF0514) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6] Vibrio vulnificus
JWSR02000001.1_404 61.947 1.81E-150 lpxD VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lpxD) UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_424 80.0 6.06E-114 gmhA/lpcA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (gmhA/lpcA) phosphoheptose isomerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_450 74.734 0.0 flaE VF0519 Flagella Motility VFC0204 Single polar flagellum (flaE) secreted flagellin involved in biofilm formation [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_451 83.862 0.0 flaD VF0519 Flagella Motility VFC0204 Single polar flagellum (flaD) flagellin [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_452 82.713 0.0 flaB VF0519 Flagella Motility VFC0204 Single polar flagellum (flaB) flagellin [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_454 64.881 0.0 fliD VF0519 Flagella Motility VFC0204 Single polar flagellum (fliD) flagellar hook-associated protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_456 86.765 9.18E-88 fliS VF0519 Flagella Motility VFC0204 Single polar flagellum (fliS) flagellar protein FliS [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_458 78.893 0.0 flrA VF0519 Flagella Motility VFC0204 Single polar flagellum (flrA) sigma-54 dependent transcriptional activator [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_459 84.29 0.0 fleS/flrB VF0519 Flagella Motility VFC0204 Single polar flagellum (fleS/flrB) sensory box sensor histidine kinase [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_460 83.824 0.0 fleR/flrC VF0519 Flagella Motility VFC0204 Single polar flagellum (fleR/flrC) sigma-54 dependent response regulator [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_461 75.728 1.15E-55 fliE VF0519 Flagella Motility VFC0204 Single polar flagellum (fliE) flagellar hook-basal body protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_462 81.271 0.0 fliF VF0519 Flagella Motility VFC0204 Single polar flagellum (fliF) flagellar M-ring protein FliF [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_463 86.994 0.0 fliG VF0519 Flagella Motility VFC0204 Single polar flagellum (fliG) flagellar motor protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_464 69.925 3.86E-141 fliH VF0519 Flagella Motility VFC0204 Single polar flagellum (fliH) flagellar assembly protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_465 91.304 0.0 fliI VF0519 Flagella Motility VFC0204 Single polar flagellum (fliI) flagellum-specific ATP synthase [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_466 69.231 2.95E-73 fliJ VF0519 Flagella Motility VFC0204 Single polar flagellum (fliJ) flagellar protein FliJ [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_468 75.595 3.11E-89 fliL VF0519 Flagella Motility VFC0204 Single polar flagellum (fliL) flagellar basal body-associated protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_469 87.536 0.0 fliM VF0519 Flagella Motility VFC0204 Single polar flagellum (fliM) flagellar motor switch protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_470 88.971 2.05E-85 fliN VF0519 Flagella Motility VFC0204 Single polar flagellum (fliN) flagellar motor switch protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_471 65.766 1.19E-41 fliO VF0519 Flagella Motility VFC0204 Single polar flagellum (fliO) flagellar protein FliO [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_472 79.779 1.21E-150 fliP VF0519 Flagella Motility VFC0204 Single polar flagellum (fliP) flagellar biosynthesis protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_473 84.27 3.09E-53 fliQ VF0519 Flagella Motility VFC0204 Single polar flagellum (fliQ) flagellar biosynthesis protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_474 78.462 7.77E-157 fliR VF0519 Flagella Motility VFC0204 Single polar flagellum (fliR) flagellar biosynthesis protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_475 82.447 0.0 flhB VF0519 Flagella Motility VFC0204 Single polar flagellum (flhB) flagellar biosynthesis protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_476 90.415 0.0 flhA VF0519 Flagella Motility VFC0204 Single polar flagellum (flhA) flagellar biosynthesis protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_477 74.9 0.0 flhF VF0519 Flagella Motility VFC0204 Single polar flagellum (flhF) flagellar biosynthesis protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_478 91.864 0.0 fleN/flhG VF0519 Flagella Motility VFC0204 Single polar flagellum (fleN/flhG) MinD-like ATPase [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_479 82.377 2.13E-154 fliA VF0519 Flagella Motility VFC0204 Single polar flagellum (fliA) flagellar biosynthesis sigma factor FliA [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_480 97.541 3.12E-85 cheY VF0519 Flagella Motility VFC0204 Single polar flagellum (cheY) chemotaxis protein CheY [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_481 69.106 4.83E-120 cheZ VF0519 Flagella Motility VFC0204 Single polar flagellum (cheZ) chemotaxis protein CheZ [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_482 72.864 0.0 cheA VF0519 Flagella Motility VFC0204 Single polar flagellum (cheA) chemotaxis protein CheA [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_483 83.82 0.0 cheB VF0519 Flagella Motility VFC0204 Single polar flagellum (cheB) chemotaxis-specific methylesterase [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_484 62.302 4.52E-121 AHML_RS07540 VF0473 Polar flagella Motility VFC0204 Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments (AHML_RS07540) CobQ/CobB/MinD/ParA family protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
JWSR02000001.1_486 92.683 4.69E-111 cheW VF0519 Flagella Motility VFC0204 Single polar flagellum (cheW) purine-binding chemotaxis protein CheW [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_575 66.146 2.5E-98 sodB VF0169 SodB Stress survival VFC0282 (sodB) superoxide dismutase [SodB (VF0169) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JWSR02000001.1_580 78.983 2.42E-177 motY VF0519 Flagella Motility VFC0204 Single polar flagellum (motY) sodium-type flagellar protein MotY [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_636 77.049 8.19E-138 flmH VF0473 Polar flagella Motility VFC0204 Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments (flmH) short chain dehydrogenase/reductase family oxidoreductase [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
JWSR02000001.1_637 63.636 5.92E-29 acpXL VF0367 LPS Immune modulation VFC0258 Brucella possesses a non-classical LPS as compared with the so-called classical LPS from enterobacteria such as Escherichia coli. B. abortus lipid A possesses a diaminoglucose backbone (rather than glucosamine), and acyl groups are longer (C28 rather than C12 and C16) and are only linked to the core by amide bounds (rather than ester and amide bonds).; In contrast to enterobacterial LPSs, Brucella LPS is several-hundred-times less active and toxic than E. coli LPS.; this is an evolutionary adaptation to an intracellular lifestyle, low endotoxic activity is shared by other intracellular pathogens such as Bartonella and Legionella. (acpXL) acyl carrier protein [LPS (VF0367) - Immune modulation (VFC0258)] [Brucella melitensis bv. 1 str. 16M] Brucella melitensis
JWSR02000001.1_1055 99.324 2.44E-107 vxsC VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vxsC) transcriptional regulator ExsC [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1056 98.551 7.26E-99 virG VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (virG) Type III secretion system chaperone VscW [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1057 100.0 0.0 exsA VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (exsA) transcriptional regulator ExsA [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1058 99.387 0.0 exsD VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (exsD) transcriptional regulator ExsD [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1059 99.296 6.64E-106 vscB VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscB) type III secretion system regulatory protein, YscB homolog [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1060 99.682 0.0 vscC VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscC) type III secretion system OM ring protein VscC [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1061 100.0 0.0 vscD VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscD) type III secretion system IM ring protein VscD [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1063 100.0 9.84E-56 vscF VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscF) type III secretion system needle protein VscF [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1064 100.0 2.03E-84 vscG VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscG) Type III secretion system chaperone VscG [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1065 99.038 5.78E-154 vscH VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscH) type III secretion system protein VscH [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1066 100.0 1.97E-80 vscI VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscI) type III secretion system inner rod protein VscI [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1067 99.194 0.0 vscJ VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscJ) type III secretion system IM ring protein VscJ [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1068 99.095 1.67E-164 vscK VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscK) type III secretion system cytoplasmic protein VscK [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1069 100.0 1.3E-156 vscL VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscL) type III secretion system cytoplasmic protein VscL [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1071 98.966 0.0 vopS VF0632 T3SS1 secreted effectors Effector delivery system VFC0086 (vopS) type III secretion system effector VopS, Adenylyltransferase [T3SS1 secreted effectors (VF0632) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio cholerae
JWSR02000001.1_1073 99.692 0.0 vopR VF0632 T3SS1 secreted effectors Effector delivery system VFC0086 (vopR) Type III secretion system effector VopR, phosphoinositide-binding protein [T3SS1 secreted effectors (VF0632) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio cholerae
JWSR02000001.1_1074 99.342 5.31E-111 vecA VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vecA) Type III secretion system chaperone VecA [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1075 97.967 0.0 vopQ VF0632 T3SS1 secreted effectors Effector delivery system VFC0086 (vopQ) type III secretion system effector VopQ [T3SS1 secreted effectors (VF0632) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio cholerae
JWSR02000001.1_1076 99.715 0.0 vscU VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscU) type III secretion system C-ring protein VscU [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1077 99.617 0.0 vscT VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscT) type III secretion system C ring protein VscT [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1078 100.0 5.62E-57 vscS VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscS) type III secretion system C-ring protein VscS [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1079 100.0 3.02E-156 vscR VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscR) type III secretion system C-ring protein VscR [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1080 98.754 0.0 vscQ VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscQ) type III secretion system cytoplasmic protein VscQ [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1081 92.825 0.0 vscP VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscP) type III secretion system needle length control protein VscP [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1082 100.0 1.32E-100 vscO VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscO) type III secretion system protein YscO [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1083 99.091 0.0 vscN VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscN) type III secretion system ATPase VscN [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1084 100.0 0.0 vopN VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vopN) type III secretion system protein VopN [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1085 100.0 1.05E-62 tyeA/vcr1 VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (tyeA/vcr1) type III secretion system regulatory protein [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1086 99.187 6.11E-88 sycN/vcr2 VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (sycN/vcr2) type III secretion system regulatory protein [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1087 98.4 4.66E-89 vscX VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscX) type III secretion system C-ring protein VscX for secretion specificity [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1088 99.123 1.34E-80 vscY VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vscY) type III secretion system C-ring protein VscY for secretion specificity [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1089 100.0 0.0 vcrD VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vcrD) type III secretion system C ring protein VcrD [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1090 98.54 4.98E-101 vcrR VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vcrR) type III secretion system protein VcrR [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1091 100.0 1.08E-64 vcrG VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vcrG) type III secretion system chaperone VcrG [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1092 81.633 0.0 vcrV VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vcrV) type III secretion system needle tip protein VcrV [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1093 100.0 3.04E-121 vcrH VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vcrH) type III secretion system chaperone VcrH [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1094 98.997 0.0 vopB VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vopB) type III secretion system translocator protein VopB [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1095 99.401 0.0 vopD VF0408 T3SS1 Effector delivery system VFC0086 Chromosome I encoded; similar to the Ysc secretion system in Yersinia; T3SS1 genes are positively regulated by VP1699 and negatively regulated by VP1698 (vopD) type III secretion system translocator protein VopD [T3SS1 (VF0408) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1139 99.887 0.0 mam7 VF0512 MAM7 Adherence VFC0001 MAM7 is conserved in many Gram-negative bacteria, contains a transmembrane motif at the N terminus and seven mammalian cell entry (mce) domains that are also found in Mycobacterium spp. and some Gram positive bacteria species (mam7) multivalent adhesion molecule MAM7 [MAM7 (VF0512) - Adherence (VFC0001)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000001.1_1330 69.62 0.0 tssC VF0943 HSI-2 Effector delivery system VFC0086 P. aeruginosa encodes three distinct T6SS loci, H1- to H3-T6SS. While H1-T6SS has only been involved in antibacterial activity so far, H2-T6SS and H3-T6SS can target both bacterial and eukaryotic cells possessing even as said earlier trans-kingdom effectors. (tssC) type VI secretion system contractile sheath large subunit [HSI-2 (VF0943) - Effector delivery system (VFC0086)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JWSR02000001.1_1625 63.922 0.0 acrB VF0568 AcrAB Antimicrobial activity/Competitive advantage VFC0325 (acrB) acriflavine resistance protein B [AcrAB (VF0568) - Antimicrobial activity/Competitive advantage (VFC0325)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
JWSR02000001.1_1708 70.356 1.64E-127 nueA VF0473 Polar flagella Motility VFC0204 Types of bacterial movement: swimming, swarming, gliding, twitching and sliding. Only swimming and swarming are correlated with the presence of flagella. Swimming is an individual endeavour, while swarming is the movement of a group of bacteria; constitutively expressed for motility in liquid environments (nueA) NeuA protein [Polar flagella (VF0473) - Motility (VFC0204)] [Aeromonas hydrophila ML09-119] Aeromonas hydrophila
JWSR02000001.1_1711 61.979 0.0 msbA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (msbA) lipid transporter ATP-binding/permease [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_1772 61.78 1.86E-95 clpP VF0074 ClpP Stress survival VFC0282 21.6 kDa protein belongs to a family of proteases highly conserved in prokaryotes and eukaryotes (clpP) ATP-dependent Clp protease proteolytic subunit [ClpP (VF0074) - Stress survival (VFC0282)] [Listeria monocytogenes EGD-e] Listeria monocytogenes
JWSR02000001.1_1852 79.73 2.52E-87 fur VF0113 Fur Regulation VFC0301 (fur) ferric iron uptake transcriptional regulator [Fur (VF0113) - Regulation (VFC0301)] [Salmonella enterica subsp. enterica serovar Typhimurium str. LT2] Salmonella enterica (serovar typhimurium)
JWSR02000001.1_1890 84.127 0.0 flaD VF0519 Flagella Motility VFC0204 Single polar flagellum (flaD) flagellin [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1892 76.623 0.0 flaA VF0519 Flagella Motility VFC0204 Single polar flagellum (flaA) flagellin [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1893 69.27 0.0 flgL VF0519 Flagella Motility VFC0204 Single polar flagellum (flgL) flagellar hook-associated protein 3 FlgL [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1894 67.802 0.0 flgK VF0519 Flagella Motility VFC0204 Single polar flagellum (flgK) flagellar hook-associated protein 1 FlgK [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1895 62.857 1.54E-136 flgJ VF0519 Flagella Motility VFC0204 Single polar flagellum (flgJ) peptidoglycan hydrolase [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1896 87.393 0.0 flgI VF0519 Flagella Motility VFC0204 Single polar flagellum (flgI) flagellar P-ring protein precursor FlgI [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1897 74.793 8.89E-133 flgH VF0519 Flagella Motility VFC0204 Single polar flagellum (flgH) flagellar L-ring protein precursor FlgH [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1898 85.878 5.42E-173 flgG VF0519 Flagella Motility VFC0204 Single polar flagellum (flgG) flagellar basal-body rod protein FlgG [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1899 81.526 2.45E-154 flgF VF0519 Flagella Motility VFC0204 Single polar flagellum (flgF) flagellar basal-body rod protein FlgF [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1900 81.693 0.0 flgE VF0519 Flagella Motility VFC0204 Single polar flagellum (flgE) flagellar hook protein FlgE [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1901 84.681 7.57E-146 flgD VF0519 Flagella Motility VFC0204 Single polar flagellum (flgD) flagellar basal-body rod modification protein FlgD [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1902 89.13 1.75E-86 flgC VF0519 Flagella Motility VFC0204 Single polar flagellum (flgC) flagellar basal body rod protein FlgC [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1903 82.443 9.8E-83 flgB VF0519 Flagella Motility VFC0204 Single polar flagellum (flgB) flagellar basal body rod protein FlgB [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1904 93.091 0.0 cheR VF0519 Flagella Motility VFC0204 Single polar flagellum (cheR) chemotaxis protein methyltransferase CheR [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1905 86.688 0.0 cheV VF0519 Flagella Motility VFC0204 Single polar flagellum (cheV) chemotaxis protein CheV [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1907 63.208 2.88E-42 flgM VF0519 Flagella Motility VFC0204 Single polar flagellum (flgM) negative regulator of flagellin synthesis FlgM, putative [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1908 69.504 2.08E-71 flgN VF0519 Flagella Motility VFC0204 Single polar flagellum (flgN) flagellar biosynthesis chaperone FlgN [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1909 83.077 4.91E-75 flgP VF0519 Flagella Motility VFC0204 Single polar flagellum (flgP) Vibrio-specific flagellar H-ring component FlgP [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1910 85.849 2.38E-141 flgO VF0519 Flagella Motility VFC0204 Single polar flagellum (flgO) Vibrio-specific flagellar H-ring component FlgO [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1911 73.867 0.0 flgT VF0519 Flagella Motility VFC0204 Single polar flagellum (flgT) Vibrio-specific flagellar H-ring component FlgT [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1928 80.071 4.89E-174 kdsA VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (kdsA) 2-dehydro-3-deoxyphosphooctonate aldolase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_1969 84.758 1.76E-161 IlpA VF0513 IlpA Adherence VFC0001 (IlpA) immunogenic lipoprotein A [IlpA (VF0513) - Adherence (VFC0001)] [Vibrio vulnificus YJ016] Vibrio vulnificus
JWSR02000001.1_1983 82.484 0.0 motB VF0519 Flagella Motility VFC0204 Single polar flagellum (motB) flagellar motor protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_1984 90.119 5.17E-158 motA VF0519 Flagella Motility VFC0204 Single polar flagellum (motA) flagellar motor protein [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000001.1_2094 60.89 0.0 icl VF0253 Isocitrate lyase Others VFC0346 (icl) Isocitrate lyase Icl (isocitrase) (isocitratase) [Isocitrate lyase (VF0253) - Others (VFC0346)] [Mycobacterium tuberculosis H37Rv] Mycobacterium tuberculosis
JWSR02000001.1_2207 74.342 2.89E-173 lpxC VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lpxC) UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_2244 65.021 0.0 rfaE VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rfaE) ADP-heptose synthase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_2428 77.062 0.0 ugd VF0560 Capsule Immune modulation VFC0258 The Klebsiella polysaccharide capsule is produced through a Wzy-dependent process, for which the synthesis and export machinery are encoded in a single 10-30 kb region of the genome known as the K locus.; 78 distinct capsule phenotypes have been recognized by serological typing, but many isolates are serologically non-typable.; capsular serotypes vary substantially in the degree of serum resistance; K1, K2 and K5 are highly serum resistant and are associated with hypervirulent strains that differ from classical K. pneumoniae in that they commonly cause community-acquired disease. (ugd) UDP-glucose 6-dehydrogenase [Capsule (VF0560) - Immune modulation (VFC0258)] [Klebsiella pneumoniae subsp. pneumoniae NTUH-K2044] Klebsiella pneumoniae
JWSR02000001.1_2435 63.983 0.0 YE_RS15420 VF0392 O-antigen Immune modulation VFC0258 Clinical Y. enterocolitica isolates from humans predominantly belong to serotypes O:3, O:9, O:8 and O:5,27; Y. enterocolitica O antigen expression is temperature regulated. (YE_RS15420) mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
JWSR02000001.1_2437 73.585 0.0 YE_RS15425 VF0392 O-antigen Immune modulation VFC0258 Clinical Y. enterocolitica isolates from humans predominantly belong to serotypes O:3, O:9, O:8 and O:5,27; Y. enterocolitica O antigen expression is temperature regulated. (YE_RS15425) GDP-L-fucose synthase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
JWSR02000001.1_2438 81.989 0.0 gmd VF0392 O-antigen Immune modulation VFC0258 Clinical Y. enterocolitica isolates from humans predominantly belong to serotypes O:3, O:9, O:8 and O:5,27; Y. enterocolitica O antigen expression is temperature regulated. (gmd) GDP-mannose 4,6-dehydratase [O-antigen (VF0392) - Immune modulation (VFC0258)] [Yersinia enterocolitica subsp. enterocolitica 8081] Yersinia enterocolitica
JWSR02000001.1_2455 74.038 5.01E-171 rfaD VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rfaD) ADP-L-glycero-D-mannoheptose-6-epimerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_2472 65.753 4.18E-143 wbtL VF0542 LPS Immune modulation VFC0258 The structure of Francisella spp. lipid A is unique in that it is modified by various carbohydrates that greatly reduce TLR4 activation and allow for immune evasion (wbtL) glucose-1-phosphate thymidylyltransferase [LPS (VF0542) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JWSR02000001.1_2473 64.565 2.51E-168 rffG VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (rffG) dTDP-glucose 46-dehydratase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_2477 63.095 3.74E-115 lgtF VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (lgtF) beta-1,4-glucosyltransferase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000001.1_2528 66.071 7.77E-157 epsK VF0613 Eps T2SS Effector delivery system VFC0086 (epsK) type II secretion system minor pseudopilin GspK [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395] Vibrio cholerae
JWSR02000001.1_2529 62.78 3.24E-101 epsJ VF0613 Eps T2SS Effector delivery system VFC0086 (epsJ) type II secretion system minor pseudopilin GspJ [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395] Vibrio cholerae
JWSR02000001.1_2530 80.357 5.24E-62 epsI VF0613 Eps T2SS Effector delivery system VFC0086 (epsI) type II secretion system minor pseudopilin GspI [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395] Vibrio cholerae
JWSR02000001.1_2532 90.278 2.03E-95 epsG VF0613 Eps T2SS Effector delivery system VFC0086 (epsG) type II secretion system major pseudopilin GspG [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395] Vibrio cholerae
JWSR02000001.1_2533 79.259 0.0 epsF VF0613 Eps T2SS Effector delivery system VFC0086 (epsF) type II secretion system inner membrane protein GspF [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395] Vibrio cholerae
JWSR02000001.1_2534 84.114 0.0 epsE VF0613 Eps T2SS Effector delivery system VFC0086 (epsE) type II secretion system ATPase GspE [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395] Vibrio cholerae
JWSR02000001.1_2535 82.318 0.0 epsD VF0613 Eps T2SS Effector delivery system VFC0086 (epsD) type II secretion system secretin GspD [Eps T2SS (VF0613) - Effector delivery system (VFC0086)] [Vibrio cholerae O395] Vibrio cholerae
JWSR02000002.1_60 77.919 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JWSR02000002.1_121 74.811 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JWSR02000002.1_159 85.308 8.85E-135 motX VF0519 Flagella Motility VFC0204 Single polar flagellum (motX) sodium-type flagellar protein MotX [Flagella (VF0519) - Motility (VFC0204)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000002.1_174 66.337 7.45E-101 vfr VF0082 Type IV pili Adherence VFC0001 PilA, B, C, D, E, F, M, N, O, P, Q, T, U, V, W, X, Y1, Y2, Z, and fimT, U, V are involved in the biogenesis and mechanical function of pili, pilG, H, I, K, chpA, B, C, D, E, pilS, R, fimS, rpoN, algR, algU, and vfr are involved in transcriptional regulation and chemosensory pathways that control the expression or activity of the twitching motility of the pili (vfr) cAMP-regulatory protein [Type IV pili (VF0082) - Adherence (VFC0001)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JWSR02000002.1_195 77.919 0.0 tufA VF0460 EF-Tu Adherence VFC0001 (tufA) elongation factor Tu [EF-Tu (VF0460) - Adherence (VFC0001)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JWSR02000002.1_223 64.865 5.17E-100 rpe VF0543 Capsule Immune modulation VFC0258 Group 4 capsule; high molecular weight (HMW) O-antigen capsule (rpe) ribulose-phosphate 3-epimerase [Capsule (VF0543) - Immune modulation (VFC0258)] [Francisella tularensis subsp. tularensis SCHU S4] Francisella tularensis
JWSR02000004.1_256 69.897 0.0 gbpA VF0619 GbpA Adherence VFC0001 Mucin contains extensively different types of carbohydrates, the residue, N-acetyl-D-glucosamine (GlcNAc), is one of the most abundant sugars in the carbohydrate side chains (gbpA) N-acetylglucosamine-binding protein GbpA [GbpA (VF0619) - Adherence (VFC0001)] [Vibrio cholerae O1 biovar El Tor str. N16961] Vibrio cholerae
JWSR02000004.1_305 62.682 0.0 lfhA VF0474 Lateral flagella Motility VFC0204 (lfhA) lateral flagellar biosynthesis protein [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449] Aeromonas salmonicida
JWSR02000004.1_308 60.674 4.91E-32 fliQ VF0273 Flagella Motility VFC0204 (fliQ) flagellar biosynthetic protein FliQ [Flagella (VF0273) - Motility (VFC0204)] [Pseudomonas aeruginosa PAO1] Pseudomonas aeruginosa
JWSR02000004.1_309 67.826 1.76E-102 fliP VF0474 Lateral flagella Motility VFC0204 (fliP) flagellar biosynthesis protein FliP [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449] Aeromonas salmonicida
JWSR02000004.1_318 60.497 0.0 lfiI VF0474 Lateral flagella Motility VFC0204 (lfiI) lateral flagellar FliI-like assembly ATPase [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449] Aeromonas salmonicida
JWSR02000004.1_425 74.419 0.0 katA VF0454 KatA Stress survival VFC0282 (katA) catalase [KatA (VF0454) - Stress survival (VFC0282)] [Neisseria meningitidis MC58] Neisseria meningitidis
JWSR02000004.1_476 63.469 5.74E-129 vopA/vopP VF0633 T3SS2 secreted effectors Effector delivery system VFC0086 (vopA/vopP) type III secretion system effector VopA, acetyltransferase [T3SS2 secreted effectors (VF0633) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio cholerae
JWSR02000004.1_481 68.712 8.93E-78 vscJ2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscJ2) type III secretion system protein VscJ2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_485 73.352 2.28E-180 vopB2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vopB2) type III secretion system translocator protein VopB2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_486 71.889 1.17E-113 vopD2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vopD2) type III secretion system translocator protein VopD2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_493 75.598 0.0 vcrD2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vcrD2) type III secretion system protein [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_494 75.652 0.0 vscU2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscU2) type III secretion system protein [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_498 70.681 1.48E-97 VP_RS21630 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (VP_RS21630) putative type III secretion system protein [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_499 67.143 3.85E-32 vscQ2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscQ2) type III secretion protein VscQ2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_500 68.852 2.79E-90 VP_RS21620 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (VP_RS21620) winged helix-turn-helix domain-containing protein [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_502 78.947 4.52E-113 vscR2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscR2) type III secretion system C-ring protein VscR2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_503 68.282 1.08E-113 vscT2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscT2) type III secretion system C-ring protein VscT2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_505 77.893 0.0 vscC2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscC2) type III secretion system protein VscC2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_506 89.762 0.0 vscN2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscN2) type III secretion system ATPase VscN2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_509 77.922 1.71E-39 vscS2 VF0409 T3SS2 Effector delivery system VFC0086 Chromosome II encoded; similar to the Inv-Mxi-Spa secretion system in Salmonella and Shigella (vscS2) type III secretion system protein VscS2 [T3SS2 (VF0409) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_531 60.633 0.0 ureB VF0050 Urease Stress survival VFC0282 (ureB) urease beta subunit UreB, urea amidohydrolase [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JWSR02000004.1_534 65.816 2.77E-93 ureG VF0050 Urease Stress survival VFC0282 (ureG) urease accessory protein (ureG) [Urease (VF0050) - Stress survival (VFC0282)] [Helicobacter pylori 26695] Helicobacter pylori
JWSR02000004.1_536 97.884 5.61E-141 tdh VF0517 TDH Exotoxin VFC0235 (tdh) thermostable direct hemolysin A [TDH (VF0517) - Exotoxin (VFC0235)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus
JWSR02000004.1_544 83.432 2.16E-108 hlyC VF0225 Alpha-Hemolysin Exotoxin VFC0235 Best-characterized RTX protein secreted by a type I secretion system: the structural gene encoding the hemolysin (hlyA) is part of an operon that also encodes a dedicated export system (HlyB and HlyD comprising a type I secretion system) and a toxin modifying enzyme (HlyC). The HlyC protein is responsible for acylation of HlyA, resulting in toxin activation; The hly operon is found on a plasmid of EHEC O157:H7, while the hly operon is often located adjacent to the P fimbrial genes on the same pathogenicity island on the chromosome of UPEC strains (hlyC) Hemolysin C [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073] Escherichia coli (UPEC)
JWSR02000004.1_545 80.364 0.0 hlyA VF0225 Alpha-Hemolysin Exotoxin VFC0235 Best-characterized RTX protein secreted by a type I secretion system: the structural gene encoding the hemolysin (hlyA) is part of an operon that also encodes a dedicated export system (HlyB and HlyD comprising a type I secretion system) and a toxin modifying enzyme (HlyC). The HlyC protein is responsible for acylation of HlyA, resulting in toxin activation; The hly operon is found on a plasmid of EHEC O157:H7, while the hly operon is often located adjacent to the P fimbrial genes on the same pathogenicity island on the chromosome of UPEC strains (hlyA) Hemolysin A [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073] Escherichia coli (UPEC)
JWSR02000004.1_546 91.796 0.0 hlyB VF0225 Alpha-Hemolysin Exotoxin VFC0235 Best-characterized RTX protein secreted by a type I secretion system: the structural gene encoding the hemolysin (hlyA) is part of an operon that also encodes a dedicated export system (HlyB and HlyD comprising a type I secretion system) and a toxin modifying enzyme (HlyC). The HlyC protein is responsible for acylation of HlyA, resulting in toxin activation; The hly operon is found on a plasmid of EHEC O157:H7, while the hly operon is often located adjacent to the P fimbrial genes on the same pathogenicity island on the chromosome of UPEC strains (hlyB) Hemolysin B [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073] Escherichia coli (UPEC)
JWSR02000004.1_547 80.753 0.0 hlyD VF0225 Alpha-Hemolysin Exotoxin VFC0235 Best-characterized RTX protein secreted by a type I secretion system: the structural gene encoding the hemolysin (hlyA) is part of an operon that also encodes a dedicated export system (HlyB and HlyD comprising a type I secretion system) and a toxin modifying enzyme (HlyC). The HlyC protein is responsible for acylation of HlyA, resulting in toxin activation; The hly operon is found on a plasmid of EHEC O157:H7, while the hly operon is often located adjacent to the P fimbrial genes on the same pathogenicity island on the chromosome of UPEC strains (hlyD) Hemolysin D [Alpha-Hemolysin (VF0225) - Exotoxin (VFC0235)] [Escherichia coli CFT073] Escherichia coli (UPEC)
JWSR02000004.1_949 61.538 6.0E-153 galE VF0044 LOS Immune modulation VFC0258 Lic1A (phosphorylcholine (ChoP) kinase) 5'-CAAT-3' within the 5'-end of its coding sequence; lic2A, also referred to as lexA, variation in the number of 5'-CAAT-3' repeats has been shown to correlate directly with phase variation of the Gal-alpha(1-4)beta-Gal LPS structure; But lgtC (glycosyltransferase), another phase-variable gene, ultimately dictates whether this structure is synthesized. lic3A encode a sialyl transferase which directs the substitution of LPS with sialic acid. (galE) UDP-glucose 4-epimerase [LOS (VF0044) - Immune modulation (VFC0258)] [Haemophilus influenzae Rd KW20] Haemophilus influenzae
JWSR02000004.1_1064 76.763 0.0 katB VF0168 KatAB Stress survival VFC0282 (katB) catalase-peroxidase KatB [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JWSR02000004.1_1103 65.246 1.89E-142 VV1_RS15615 VF0612 Flp pili Adherence VFC0001 Flp pili are polymers of the mature Flp pilin protein, and they are assembled and secreted by a complex of proteins encoded by the tad operon. (VV1_RS15615) type II secretion system F family protein [Flp pili (VF0612) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6] Vibrio vulnificus
JWSR02000004.1_1104 86.461 0.0 VV1_RS15610 VF0612 Flp pili Adherence VFC0001 Flp pili are polymers of the mature Flp pilin protein, and they are assembled and secreted by a complex of proteins encoded by the tad operon. (VV1_RS15610) CpaF family protein [Flp pili (VF0612) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6] Vibrio vulnificus
JWSR02000004.1_1107 71.946 0.0 VV1_RS15595 VF0612 Flp pili Adherence VFC0001 Flp pili are polymers of the mature Flp pilin protein, and they are assembled and secreted by a complex of proteins encoded by the tad operon. (VV1_RS15595) pilus assembly protein N-terminal domain-containing protein [Flp pili (VF0612) - Adherence (VFC0001)] [Vibrio vulnificus CMCP6] Vibrio vulnificus
JWSR02000004.1_1359 78.792 0.0 katB VF0168 KatAB Stress survival VFC0282 (katB) catalase-peroxidase KatB [KatAB (VF0168) - Stress survival (VFC0282)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JWSR02000004.1_1361 85.906 5.66E-98 ati1 VF0479 T3SS Effector delivery system VFC0086 Similar to the Yersinia T3SS (ati1) Ati2 chaperone [T3SS (VF0479) - Effector delivery system (VFC0086)] [Aeromonas salmonicida subsp. salmonicida A449] Aeromonas salmonicida
JWSR02000004.1_1362 99.396 0.0 VPA0450 VF0632 T3SS1 secreted effectors Effector delivery system VFC0086 (VPA0450) type III secretion system effector [T3SS1 secreted effectors (VF0632) - Effector delivery system (VFC0086)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio cholerae
JWSR02000004.1_1495 72.467 0.0 htpB VF0159 Hsp60 Adherence VFC0001 (htpB) Hsp60, 60K heat shock protein HtpB [Hsp60 (VF0159) - Adherence (VFC0001)] [Legionella pneumophila subsp. pneumophila str. Philadelphia 1] Legionella pneumophila
JWSR02000004.1_1510 60.748 1.2E-88 lfgH VF0474 Lateral flagella Motility VFC0204 (lfgH) lateral flagellar L-ring protein, LfgH [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449] Aeromonas salmonicida
JWSR02000004.1_1511 68.966 4.97E-130 lfgG VF0474 Lateral flagella Motility VFC0204 (lfgG) lateral flagellar basal-body rod protein LfgG [Lateral flagella (VF0474) - Motility (VFC0204)] [Aeromonas salmonicida subsp. salmonicida A449] Aeromonas salmonicida
JWSR02000004.1_1552 99.041 0.0 tlh VF0610 TLH Exotoxin VFC0235 High-conserved and widely distributed among Vibrio species; a full-protein of 418 amino acids (MW~47.3 kDa), and a post-transductional modification removes the N-terminal signal peptide, leaving a mature protein of 399 amino acids (tlh) thermolabile hemolysin TLH [TLH (VF0610) - Exotoxin (VFC0235)] [Vibrio parahaemolyticus RIMD 2210633] Vibrio parahaemolyticus