Bioactive Compounds List
Type Distribution
Max Phase Distribution
Bioactive Compounds List
| Bio ID | Target ID | Target Name | ChEMBL ID | Name | Type | Max Phase | Molecular Weight | Targets | Bioactivities | Molecular Formula | Details |
|---|---|---|---|---|---|---|---|---|---|---|---|
| bio3401 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL2017974 | BUPARLISIB | Small molecule | Phase 3 | 410.40 | 361.0 | 625.0 | C18H21F3N6O2 | Details |
| bio3402 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL1944698 | ZOTIRACICLIB | Small molecule | Phase 2 | 372.47 | 319.0 | 380.0 | C23H24N4O | Details |
| bio3403 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL3544914 | TEZACAFTOR | Small molecule | Phase 4 | 520.50 | 58.0 | 82.0 | C26H27F3N2O6 | Details |
| bio3404 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL4559134 | SELPERCATINIB | Small molecule | Phase 4 | 525.61 | 6.0 | 25.0 | C29H31N7O3 | Details |
| bio3405 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL3989970 | MAVELERTINIB | Small molecule | Phase 2 | 415.43 | 27.0 | 99.0 | C18H22FN9O2 | Details |
| bio3406 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL3931971 | RAZUPROTAFIB | Small molecule | Phase 2 | 586.72 | 1.0 | 1.0 | C26H26N4O6S3 | Details |
| bio3407 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL5095139 | PALSUCIBEP PEGOL | Protein | Phase 2 | -- | -- | -- | -- | Details |
| bio3408 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL4594281 | DUBERMATINIB TARTRATE | Small molecule | Phase 1 | 816.24 | -- | -- | C32H42ClN7O14S | Details |
| bio3409 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL5095167 | BEFOTERTINIB | Small molecule | Phase 2 | 567.62 | -- | -- | C29H32F3N7O2 | Details |
| bio3410 | Tar18 | Serine/threonine-protein kinase cot (COT) | CHEMBL4297629 | NEDISERTIB | Small molecule | Phase 1 | 481.92 | 4.0 | 6.0 | C24H21ClFN5O3 | Details |