Bioactive Compound Details

BioIDbio1129
NameCAMPTOTHECIN
ChEMBL IDCHEMBL65
Molecular FormulaC20H16N2O4
Molecular Weight348.36
Molecular Weight (Monoisotopic)348.111
TypeSmall molecule
Max PhaseUnknown
Target IDTar11
Target NameProto-oncogene c-RAF (c-RAF)
SynonymsCAMPTOTHECINE|Camptothecin|NSC-94600|TOPOTECAN RELATED COMPOUND C
SmilesCC[C@@]1(O)C(=O)OCc2c1cc1n(c2=O)Cc2cc3ccccc3nc2-1
InchiInChI=1S/C20H16N2O4/c1-2-20(25)14-8-16-17-12(7-11-5-3-4-6-15(11)21-17)9-22(16)18(23)13(14)10-26-19(20)24/h3-8,25H,2,9-10H2,1H3/t20-/m0/s1
Inchi KeyVSJKWCGYPAHWDS-FQEVSTJZSA-N
Molecular SpeciesNEUTRAL
Targets958.0
Bioactivities5838.0
Np Likeness Score1.01
Records Key['Camptothecin', 'Camptothecin', '1', 'Camp/CPT', 'camptothecin', 'CPT', '1', '1', 'Camptothecin', 'Camptothecin', 'camptothecin', 'CPT', 'Complex 1', 'Camptothecin', '(20S0-(-)camptothecan(1)', 'Camptothecin', 'Camptothecin', '1 (Camptothecin)', '1a (20S)', 'camptothecin', 'Camptothecin', 'CPT', 'CPT', 'Camptothecin', 'CPT', '1', 'Camptothecin (table 1)', 'CPT', '1 (Camptothecin)', 'CPT', 'Camptothecin', '1 (CPT)', '1, CPT', '1 (Camptothecin)', '1, CPT', 'Camptothecin', 'CPT', 'Camptothecin', 'Camptothecin', 'Campothecin', 'CPT', 'CPT', '1 (Camptothecin, CPT)', '1', 'Camptothecin', '1, CPT', 'CPT', 'camptothecan', 'camptothecin', 'Camptothecin', '1', 'camptothecin', 'Camptothecin', 'SID26747154', 'SID11111011', 'C (20)(S)-1', 'Camptothecin', 'Camptothecin', '1a (Camptothecin)', 'CPT', '2 (Camptothecin)', 'CPT', 'Camptothecin', 'Camptothecin', 'Camptothecin', '1', 'Camptothecin', 'camptothecin', 'CPT', 'Camptothecin', 'CPT', '1, Camptothecin', '1 (Camptothecin)', 'camptothecin', 'SID11113913', 'CPT', '2, camptothecin', '2', 'Camptothecin', 'Cpt, camptothecin', 'Camptothecin', 'CPT', 'Camptothecin', '(20S)-Camptothecin(1)(094600)', '1', 'camptothecin', 'Camptothecin', 'CPT', 'CPT', 'Camptothecin', '1', 'CPT', 'Camptothecin', 'I, CPT', 'CPT', 'CPT', 'Camptothecin', 'Camptothecin', '1, CPT', 'Camptothecin', 'CPT', 'camptothecin', 'camptothecin', 'Camptothecin', '1, CPT', 'camptothecin', 'Camptothecin', 'Camptothecin', 'camptothecin', 'Camptothecin', 'Camptothecin', '1, camptothecin', 'Camptothecin', 'Camptothecin', 'camptothecin', 'camptothecin', '1', '1', '2', 'camptothecin', 'camptothecin', 'CPT', 'Camptothecin', 'CPT', 'CPT', 'CPT', 'Camptothecin', 'CPT, campothecin', 'Camptothecin', 'camptothecin', 'camptothecin', 'CPT', 'Camptothecin', 'Camptothecin', '1', 'Camptothecin', 'CPT, camptothecin', 'camptothecin', 'Camptothecin', 'CPT', '(S)-(+)-Camptothecin', 'camptothecin', 'camptothecin', '1, CPT', 'Camptothecin', 'SID50104726', '1, CPT', 'Camptothecin', 'Camptothecin', '1, CPT', '1, CPT', 'Camptothecin', 'Camptothecin', 'camptothecin', '1, camptothecin, CPT', '1', 'CPT', 'CPT', 'Camptothecin', 'Camptothecin', 'Camptothecin', 'camptothecin', 'camptothecin', 'CPT', '1, NSC-94600', 'CPT', 'Camptothecin', 'camptothecin', 'Camptothecin', 'CPT', 'SID26732559', 'camptothecin', 'camptothecin', 'CPT', 'camptothecin', '1, Camptothecin', 'Camptothecin', 'CPT', 'camptothecin', 'Camptothecin', '3', 'Camptothecin', '3a, CPT, Camptothecin', 'camptothecin', 'Camptothecin', 'CPT', 'CPT (Camptothecin)', 'Camptothecin', 'Camptotheci
Records Name['(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 4-ethyl-4-hydroxy-(4S)-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione", "4-ethyl-4-hydroxy-(4S)-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14-dione", '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', 'Camptothecin', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione (Camptothecin)', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-dione', 'Camptothecin', '(S)-4-Ethyl-4-hydroxy-1,12-dihydro-4H-2-oxa-6,12a-diaza-dibenzo[b,h]fluorene-3,13-di
Withdrawn FlagFalse
Orphan0

Molecular Structure

2D Molecular Structure