| BioID | bio1379 |
|---|
| Name | MK-3168 C-11 |
|---|
| ChEMBL ID | CHEMBL2386714 |
|---|
| Molecular Formula | C21H21ClN4OS |
|---|
| Molecular Weight | 411.95 |
|---|
| Molecular Weight (Monoisotopic) | 412.1125 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 1 |
|---|
| Target ID | Tar11 |
|---|
| Target Name | Proto-oncogene c-RAF (c-RAF) |
|---|
| Synonyms | 11C-MK-3168|MK-3168 C-11 |
|---|
| Smiles | CN(C)C(=O)[C@H]1C[C@@H]1c1ccc(-c2ncn([11CH3])c2Sc2ccc(Cl)cn2)cc1 |
|---|
| Inchi | InChI=1S/C21H21ClN4OS/c1-25(2)20(27)17-10-16(17)13-4-6-14(7-5-13)19-21(26(3)12-24-19)28-18-9-8-15(22)11-23-18/h4-9,11-12,16-17H,10H2,1-3H3/t16-,17+/m1/s1/i3-1 |
|---|
| Inchi Key | WRBFPGYDKJBYBI-LGNYVVAJSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 4.0 |
|---|
| Bioactivities | 5.0 |
|---|
| Np Likeness Score | -1.23 |
|---|
| Records Key | ['MK-3168 C-11', '[11C]-6, MK-3168'] |
|---|
| Records Name | ['MK-3168 C-11', '(1S,2S)-2-(4-{5-[(5-Chloropyridin-2-yl)thio]-1-[11C]methyl-1H-imidazol-4-yl}phenyl)-N,N-dimethylcyclopropanecarboxamide'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 0 |
|---|
