| BioID | bio1486 |
|---|
| Name | CCX354 |
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| ChEMBL ID | CHEMBL4444976 |
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| Molecular Formula | C22H22ClN7O2 |
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| Molecular Weight | 451.92 |
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| Molecular Weight (Monoisotopic) | 451.1524 |
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| Type | Small molecule |
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| Max Phase | Phase 2 |
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| Target ID | Tar11 |
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| Target Name | Proto-oncogene c-RAF (c-RAF) |
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| Synonyms | CCX-354|CCX354|CCX354-C|GSK-2941266|GSK2941266 |
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| Smiles | COc1cc(N2CCN(C(=O)Cn3nc(-c4ncc[nH]4)c4cccnc43)CC2)ccc1Cl |
|---|
| Inchi | InChI=1S/C22H22ClN7O2/c1-32-18-13-15(4-5-17(18)23)28-9-11-29(12-10-28)19(31)14-30-22-16(3-2-6-26-22)20(27-30)21-24-7-8-25-21/h2-8,13H,9-12,14H2,1H3,(H,24,25) |
|---|
| Inchi Key | ZIMLRKWQDLVPEK-UHFFFAOYSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 2.0 |
|---|
| Bioactivities | 4.0 |
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| Np Likeness Score | -1.89 |
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| Records Key | ['CCX354', '4; CCX354', '4; CCX-354'] |
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| Records Name | ['CCX354', '2-(3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)-1-(4-(4-chloro-3-methoxyphenyl)piperazin-1-yl)ethanone', '2-(3-(1H-imidazol-2-yl)-1H-pyrazolo[3,4-b]pyridin-1-yl)-1-(4-(4-chloro-3-methoxyphenyl)piperazin-1-yl)ethanone'] |
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| Withdrawn Flag | False |
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| Orphan | 0 |
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