| BioID | bio170238 |
|---|
| Name | BUPARLISIB |
|---|
| ChEMBL ID | CHEMBL2017974 |
|---|
| Molecular Formula | C18H21F3N6O2 |
|---|
| Molecular Weight | 410.4 |
|---|
| Molecular Weight (Monoisotopic) | 410.1678 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 3 |
|---|
| Target ID | Tar44 |
|---|
| Target Name | None |
|---|
| Synonyms | BKM-120|BKM-120NX|BKM120-NX|BUPARLISIB|Buparlisib|NVP-BKM-120|NVP-BKM120 |
|---|
| Smiles | Nc1cc(C(F)(F)F)c(-c2cc(N3CCOCC3)nc(N3CCOCC3)n2)cn1 |
|---|
| Inchi | InChI=1S/C18H21F3N6O2/c19-18(20,21)13-9-15(22)23-11-12(13)14-10-16(26-1-5-28-6-2-26)25-17(24-14)27-3-7-29-8-4-27/h9-11H,1-8H2,(H2,22,23) |
|---|
| Inchi Key | CWHUFRVAEUJCEF-UHFFFAOYSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 361.0 |
|---|
| Bioactivities | 625.0 |
|---|
| Np Likeness Score | -1.24 |
|---|
| Records Key | ['15, NVP-BKM120', '44, BKM120', '4696', 'BKM120', 'BKM120', 'BKM120', 'SID137275918', '5a', 'BUPARLISIB', 'BUPARLISIB', 'BKM120 (NVP-BKM120)', 'BKM120; NVP-BKM120', 'Buparlisib', 'Buparlisib', 'NVP-BKM120; BKM', 'BKM120 (NVP-BKM120)', 'BKM120; 27', 'BKM120', '4; BKM120', 'BKM120 (NVP-BKM120)', '4; BKM120', 'BKM120', 'BKM120 (NVP-BKM120)', '20', 'COVC-2818776470', 'BKM120', '10', 'BKM120', 'BKM120', '6; BKM120, NVP-120', 'BKM120', '6; BKM120', '6; NVP-BKM120, AN2025'] |
|---|
| Records Name | ['5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', None, '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', 'SID137275918', '5-(2,6-diMorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', 'BUPARLISIB', 'BUPARLISIB', 'BKM120 (NVP-BKM120)', 'Buparlisib', 'Buparlisib', 'Buparlisib', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', 'BKM120 (NVP-BKM120)', '5-[2,6-Bis(morpholin-4-yl)pyrimidin-4-yl]-4-(trifluoromethyl)-pyridin-2-amine', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', 'Buparlisib', 'BKM120 (NVP-BKM120)', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine; Buparlisib', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', 'BKM120 (NVP-BKM120)', 'Buparlisib', 'BUPARLISIB', '5-(2,6-Di-morpholin-4-yl-pyrimidin-4-yl)-4-trifluoromethyl-pyridin-2-ylamine', 'Buparlisib', 'Buparlisib', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', 'Buparlisib', '5-(2,6-dimorpholinopyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine', 'Buparlisib', 'Buparlisib'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 0 |
|---|
