| BioID | bio1830 |
|---|
| Name | PLIXORAFENIB |
|---|
| ChEMBL ID | CHEMBL4303729 |
|---|
| Molecular Formula | C25H21F3N6O3S |
|---|
| Molecular Weight | 542.54 |
|---|
| Molecular Weight (Monoisotopic) | 542.1348 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 2 |
|---|
| Target ID | Tar11 |
|---|
| Target Name | Proto-oncogene c-RAF (c-RAF) |
|---|
| Synonyms | FORE-8394|FORE8394|PLIXORAFENIB|PLX 8394|PLX-8394|PLX8394 |
|---|
| Smiles | O=C(c1c(F)ccc(NS(=O)(=O)N2CC[C@@H](F)C2)c1F)c1c[nH]c2ncc(-c3cnc(C4CC4)nc3)cc12 |
|---|
| Inchi | InChI=1S/C25H21F3N6O3S/c26-16-5-6-34(12-16)38(36,37)33-20-4-3-19(27)21(22(20)28)23(35)18-11-32-25-17(18)7-14(8-31-25)15-9-29-24(30-10-15)13-1-2-13/h3-4,7-11,13,16,33H,1-2,5-6,12H2,(H,31,32)/t16-/m1/s1 |
|---|
| Inchi Key | YYACLQUDUDXAPA-MRXNPFEDSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 4.0 |
|---|
| Bioactivities | 10.0 |
|---|
| Np Likeness Score | -1.14 |
|---|
| Records Key | ['PLIXORAFENIB', 'PLX8394', 'PLX8394', 'PLX8394', 'PLX8394', 'PLX8394', 'PLX8394', 'EOS101251', 'PLIXORAFENIB'] |
|---|
| Records Name | ['PLIXORAFENIB', 'PLX8394', 'PLX8394', 'PLX8394', 'PLX8394', 'PLX8394', 'PLX8394', 'PLX8394', 'PLIXORAFENIB'] |
|---|
| Withdrawn Flag | False |
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| Orphan | 0 |
|---|
