Bioactive Compound Details
| BioID | bio1872 |
|---|---|
| Name | LIFIRAFENIB MALEATE |
| ChEMBL ID | CHEMBL4298146 |
| Molecular Formula | C62H46F6N8O18 |
| Molecular Weight | 1305.08 |
| Molecular Weight (Monoisotopic) | 478.1253 |
| Type | Small molecule |
| Max Phase | Phase 1 |
| Target ID | Tar11 |
| Target Name | Proto-oncogene c-RAF (c-RAF) |
| Synonyms | BGB-283 sesqui-maleate|LIFIRAFENIB MALEATE|LIFIRAFENIB SESQUIMALEATE |
| Smiles | O=C(O)/C=C/C(=O)O.O=C(O)/C=C/C(=O)O.O=C(O)/C=C/C(=O)O.O=C1CCc2c(Oc3ccc4c(c3)[C@@H]3[C@H](O4)[C@H]3c3nc4cc(C(F)(F)F)ccc4[nH]3)ccnc2N1.O=C1CCc2c(Oc3ccc4c(c3)[C@@H]3[C@H](O4)[C@H]3c3nc4cc(C(F)(F)F)ccc4[nH]3)ccnc2N1 |
| Inchi | InChI=1S/2C25H17F3N4O3.3C4H4O4/c2*26-25(27,28)11-1-4-15-16(9-11)31-24(30-15)21-20-14-10-12(2-5-17(14)35-22(20)21)34-18-7-8-29-23-13(18)3-6-19(33)32-23;3*5-3(6)1-2-4(7)8/h2*1-2,4-5,7-10,20-22H,3,6H2,(H,30,31)(H,29,32,33);3*1-2H,(H,5,6)(H,7,8)/b;;3*2-1+/t2*20-,21-,22-;;;/m00.../s1 |
| Inchi Key | CETNPISTLYWCDC-CSKNCWRTSA-N |
| Molecular Species | NEUTRAL |
| Targets | None |
| Bioactivities | None |
| Np Likeness Score | -0.35 |
| Records Key | ['LIFIRAFENIB MALEATE'] |
| Records Name | ['LIFIRAFENIB MALEATE'] |
| Withdrawn Flag | False |
| Orphan | 0 |
Molecular Structure
