| BioID | bio1880 |
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| Name | PITTSBURGH COMPOUND B |
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| ChEMBL ID | CHEMBL207456 |
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| Molecular Formula | C14H12N2OS |
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| Molecular Weight | 255.33 |
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| Molecular Weight (Monoisotopic) | 256.067 |
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| Type | Small molecule |
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| Max Phase | Phase 2 |
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| Target ID | Tar11 |
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| Target Name | Proto-oncogene c-RAF (c-RAF) |
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| Synonyms | (11C)PIB|PIB C-11|PITTSBURGH COMPOUND B C-11|Pittsburgh compound B |
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| Smiles | [11CH3]Nc1ccc(-c2nc3ccc(O)cc3s2)cc1 |
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| Inchi | InChI=1S/C14H12N2OS/c1-15-10-4-2-9(3-5-10)14-16-12-7-6-11(17)8-13(12)18-14/h2-8,15,17H,1H3/i1-1 |
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| Inchi Key | ZQAQXZBSGZUUNL-BJUDXGSMSA-N |
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| Molecular Species | NEUTRAL |
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| Targets | 21.0 |
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| Bioactivities | 290.0 |
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| Np Likeness Score | -1.28 |
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| Records Key | ['[11C]PIB', '[11C]-PIB', 'PIB', 'PIB', 'PIB', 'B, PIB', 'PIB', 'PIB', 'PIB, 6-OH-BTA-1', '6-OH-BTA, [11C]PIB', '1a, [11C]PiB', '1, [11C]PIB', '[11C]PIB', '[11C]PIB', '[11C]PIB', '[11C]-PIB', '[11C]6-OHBTA-1, 11C-PIB', '[11C]PIB', 'PIB, [11C]6-OH-BTA-1', 'PITTSBURGH COMPOUND B', '[11C]PIB', '39, PiB, PittsburghB', '1a[13C]PiB', '[11C]PIB', '[11C]6-OH-BTA-1; PIB'] |
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| Records Name | ['[11C]-2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', '[11C]-4-methylamino-phenyl-benzothiazol-6-ol', '[11C]-2-(4-(methylamino)phenyl)-6-hydroxybenzothiazole', N-methyl-[11C]2-(4'-methylaminophenyl)-6-hydroxybenzothiazole", '[11C]-2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', "6-hydroxy-2-(4'-N-[11C]methylaminophenyl)-1,3-benzothiazole", 'Pittsburg Compound B', '[11C]-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', '[11C]-2-(4-(methylamino)phenyl)-6-hydroxybenzothiazole', "6-Hydroxy-2-(4'-N-[11C]methylaminophenyl)-1,3-benzothiazole", '[11C]-2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', 'Pittsburgh compound B', '2-(4-([11C]methylamino)phenyl)-6-hydroxybenzothiazol', "6-Hydroxy-2-(4'-N-[11C]methylaminophenyl)-1,3-benzothiazole", "N-methyl-[11C]2-(4'-methylaminophenyl)-6-hydroxybenzothiazole", '[11C]-2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', '2-(4-([11C]methylamino)phenyl)benzo[d]thiazol-6-ol', '2-(4-([11C]methylamino)phenyl)benzo[d]thiazol-6-ol', 'Pittsburgh compound B', 'PITTSBURGH COMPOUND B', '2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', '[11C]-2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', '[13C]-2-(4-(methylamino)phenyl)benzo[d]thiazol-6-ol', '[11C]-2-[4-(methylamino)phenyl]-1,3-benzothiazol-6-ol', "2-(4'-(11C-methylamino)phenyl)-6-hydroxybenzothiazole"]" |
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| Withdrawn Flag | False |
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| Orphan | 0 |
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