| BioID | bio1885 |
|---|
| Name | JHU-75528 C-11 |
|---|
| ChEMBL ID | CHEMBL476413 |
|---|
| Molecular Formula | C23H21Cl2N5O2 |
|---|
| Molecular Weight | 469.36 |
|---|
| Molecular Weight (Monoisotopic) | 469.1072 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Early Phase 1 |
|---|
| Target ID | Tar11 |
|---|
| Target Name | Proto-oncogene c-RAF (c-RAF) |
|---|
| Synonyms | 11C-JHU 75528|11C-OMAR|JHU-75528 C-11|OMAR C-11|[11C]NIDA41020 |
|---|
| Smiles | [11CH3]Oc1ccc(-c2c(C#N)c(C(=O)NN3CCCCC3)nn2-c2ccc(Cl)cc2Cl)cc1 |
|---|
| Inchi | InChI=1S/C23H21Cl2N5O2/c1-32-17-8-5-15(6-9-17)22-18(14-26)21(23(31)28-29-11-3-2-4-12-29)27-30(22)20-10-7-16(24)13-19(20)25/h5-10,13H,2-4,11-12H2,1H3,(H,28,31)/i1-1 |
|---|
| Inchi Key | MCNQUWLLXZZZAC-BJUDXGSMSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 2.0 |
|---|
| Bioactivities | 2.0 |
|---|
| Np Likeness Score | -1.51 |
|---|
| Records Key | ['[11C]3, [11C]NIDA41020', '[11C]5a', 'JHU-75528 C-11'] |
|---|
| Records Name | ['4-cyano-1-(2,4-dichlorophenyl)-5-([11C]-4-methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide', '4-Cyano-1-(2,4-dichlorophenyl)-5-(4-[11C]methoxyphenyl)-N-(piperidin-1-yl)-1H-pyrazole-3-carboxamide', 'JHU-75528 C-11'] |
|---|
| Withdrawn Flag | False |
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| Orphan | 0 |
|---|
