| BioID | bio1897 |
|---|
| Name | LY-3009120 |
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| ChEMBL ID | CHEMBL3577124 |
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| Molecular Formula | C23H29FN6O |
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| Molecular Weight | 424.52 |
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| Molecular Weight (Monoisotopic) | 424.2387 |
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| Type | Small molecule |
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| Max Phase | Phase 1 |
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| Target ID | Tar11 |
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| Target Name | Proto-oncogene c-RAF (c-RAF) |
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| Synonyms | DP-4978|LY-3009120|LY3009120|PAN-RAF INHIBITOR LY3009120 |
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| Smiles | CNc1ncc2cc(-c3cc(NC(=O)NCCC(C)(C)C)c(F)cc3C)c(C)nc2n1 |
|---|
| Inchi | InChI=1S/C23H29FN6O/c1-13-9-18(24)19(29-22(31)26-8-7-23(3,4)5)11-16(13)17-10-15-12-27-21(25-6)30-20(15)28-14(17)2/h9-12H,7-8H2,1-6H3,(H2,26,29,31)(H,25,27,28,30) |
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| Inchi Key | HHCBMISMPSAZBF-UHFFFAOYSA-N |
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| Molecular Species | NEUTRAL |
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| Targets | 40.0 |
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| Bioactivities | 108.0 |
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| Np Likeness Score | -1.35 |
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| Records Key | ['LY-3009120', 'LY3009120', 'LY3009120', 'LY3009120', 'LY3009120', '11; LY3009120', 'LY3009120', '13, LY3009120', '77; LY3009120', 'LY3009120', 'LY3009120', 'LY3009120', '1; LY3009120', 'EOS101523', '1; LY3009120'] |
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| Records Name | ['LY-3009120', 'LY3009120', 'LY3009120', 'LY3009120', 'LY3009120', '1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea', '1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea', '1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea', '1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea', '1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea', 'LY3009120', 'LY3009120', '1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea', 'LY3009120', '1-(3,3-dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea'] |
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| Withdrawn Flag | False |
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| Orphan | 0 |
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