| BioID | bio1912 |
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| Name | TEGAFUR |
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| ChEMBL ID | CHEMBL20883 |
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| Molecular Formula | C8H9FN2O3 |
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| Molecular Weight | 200.17 |
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| Molecular Weight (Monoisotopic) | 200.0597 |
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| Type | Small molecule |
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| Max Phase | Phase 4 |
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| Target ID | Tar11 |
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| Target Name | Proto-oncogene c-RAF (c-RAF) |
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| Synonyms | ATILLON|BMS-200604|CITOFUR|COPAROGIN|EXONAL|FENTAL|FRANROSE|FT-207|FTORAFUR|FULAID|FULFEEL|FURAFLUOR|FUROFUTRAN|FUTRAFUL|J356.722B|LAMAR|LIFRIL|MJF-12264|NEBERK|NITOBANIL|NSC-148958|SINOFLUROL|SUNFURAL|TEFSIEL C|TEGAFUR|TEGAFUR-URACIL|UFTORAL|YOUFUDING |
|---|
| Smiles | O=c1[nH]c(=O)n(C2CCCO2)cc1F |
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| Inchi | InChI=1S/C8H9FN2O3/c9-5-4-11(6-2-1-3-14-6)8(13)10-7(5)12/h4,6H,1-3H2,(H,10,12,13) |
|---|
| Inchi Key | WFWLQNSHRPWKFK-UHFFFAOYSA-N |
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| Molecular Species | NEUTRAL |
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| Targets | 159.0 |
|---|
| Bioactivities | 887.0 |
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| Np Likeness Score | -0.4 |
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| Records Key | ['2 (FT-207)', '2', 'Ftorafur', 'Ftorafur', 'Ftorafur', 'TEGAFUR', '12', 'TEGAFUR', 'Futraful', '1', 'Tegafur', 'SID26754499', 'SID8139878', '1, tegafur', '3, Thf-FU', 'SID144205202', 'TEGAFUR', 'TEGAFUR', 'SID144212129', '3, Thf-FU', '2', 'TEGAFUR', 'FT-207', 'SID29215356', 'FT, Ftorafur', 'TEGAFUR', 'Tegafur', '1, tegafur', 'Tegafur', 'Fluorofur', 'SID56422217', 'Ftorafur', 'SID170465809', 'COVC-0677695287', 'Fluorofur', 'TEGAFUR', '9', 'SAM001246561', 'FT-207', 'tegafur'] |
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| Records Name | ['5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione (FT-207)', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione (Ftorafur)', 'Tegafur', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione', 'TEGAFUR', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione (Futraful)', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione', 'Tegafur', 'SID26754499', 'SID8139878', '5-fluoro-1-(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione', '1-(Tetrahydro-2-furanyl)-5-fluorouracil', 'SID144205202', 'TEGAFUR', 'TEGAFUR', 'SID144212129', 'rac-1-(Tetrahydro-2-furanyl)-5-fluorouracil', '5-Fluoro-1-(tetrahydro-furan-2-yl)-1H-pyrimidine-2,4-dione', 'TEGAFUR', '(R)-Tegafur', 'SID29215356', '(R,S)-1-(Tetrahydro-2-furanyl)-5-fluorouracil', 'TEGAFUR', 'Tegafur', '5-fluoro-1-(tetrahydro-2-furyl)uracil', 'Tegafur', 'Fluorofur', 'SID56422217', 'Ftorafur', 'SID170465809', 'TEGAFUR', 'Fluorofur', 'TEGAFUR', 'Tegafur', 'C0164857', '5-fluoro-1-tetrahydrofuran-2-yl-pyrimidine-2,4-dione', 'tegafur'] |
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| Withdrawn Flag | False |
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| Orphan | 0 |
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