| BioID | bio1977 |
|---|
| Name | MAVELERTINIB |
|---|
| ChEMBL ID | CHEMBL3989970 |
|---|
| Molecular Formula | C18H22FN9O2 |
|---|
| Molecular Weight | 415.43 |
|---|
| Molecular Weight (Monoisotopic) | 415.188 |
|---|
| Type | Small molecule |
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| Max Phase | Phase 2 |
|---|
| Target ID | Tar12 |
|---|
| Target Name | Toll-like receptor 9 (TLR9) |
|---|
| Synonyms | EGFR T790M INHIBITOR PF-06747775|MAVELERTINIB|PF-06747775 |
|---|
| Smiles | C=CC(=O)N[C@@H]1CN(c2nc(Nc3cn(C)nc3OC)c3ncn(C)c3n2)C[C@H]1F |
|---|
| Inchi | InChI=1S/C18H22FN9O2/c1-5-13(29)21-11-8-28(6-10(11)19)18-23-15(14-16(24-18)26(2)9-20-14)22-12-7-27(3)25-17(12)30-4/h5,7,9-11H,1,6,8H2,2-4H3,(H,21,29)(H,22,23,24)/t10-,11-/m1/s1 |
|---|
| Inchi Key | JYIUNVOCEFIUIU-GHMZBOCLSA-N |
|---|
| Molecular Species | NEUTRAL |
|---|
| Targets | 27.0 |
|---|
| Bioactivities | 99.0 |
|---|
| Np Likeness Score | -1.11 |
|---|
| Records Key | ['MAVELERTINIB', '21; PF-06747775', 'MAVELERTINIB', 'COVC-1759979481'] |
|---|
| Records Name | ['MAVELERTINIB', 'N-((3R,4R)-4-fluoro-1-(6-(3-methoxy-1-methyl-1H-pyrazol-4-ylamino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide', 'MAVELERTINIB', 'MAVELERTINIB'] |
|---|
| Withdrawn Flag | False |
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| Orphan | 0 |
|---|
