| BioID | bio2632 |
|---|
| Name | AMBRISENTAN |
|---|
| ChEMBL ID | CHEMBL1111 |
|---|
| Molecular Formula | C22H22N2O4 |
|---|
| Molecular Weight | 378.43 |
|---|
| Molecular Weight (Monoisotopic) | 378.158 |
|---|
| Type | Small molecule |
|---|
| Max Phase | Phase 4 |
|---|
| Target ID | Tar12 |
|---|
| Target Name | Toll-like receptor 9 (TLR9) |
|---|
| Synonyms | AMBRISENTAN|Ambrisentan|Ambrisentan Mylan|GSK-1325760|GSK-1325760A|GSK1325760|GSK1325760A|LETAIRIS|LU-208075|VOLIBRIS |
|---|
| Smiles | COC(c1ccccc1)(c1ccccc1)[C@H](Oc1nc(C)cc(C)n1)C(=O)O |
|---|
| Inchi | InChI=1S/C22H22N2O4/c1-15-14-16(2)24-21(23-15)28-19(20(25)26)22(27-3,17-10-6-4-7-11-17)18-12-8-5-9-13-18/h4-14,19H,1-3H3,(H,25,26)/t19-/m1/s1 |
|---|
| Inchi Key | OUJTZYPIHDYQMC-LJQANCHMSA-N |
|---|
| Molecular Species | ACID |
|---|
| Targets | 73.0 |
|---|
| Bioactivities | 1101.0 |
|---|
| Np Likeness Score | -0.17 |
|---|
| Records Key | ['1', 'SID144205520', 'AMBRISENTAN', 'SID170465143', 'Ambrisentan', 'Ambrisentan', 'Ambrisentan脢', 'AMBRISENTAN', 'rac-2', 'Ambrisentan', '83', 'ambrisentan', 'ambrisentan', 'AMBRISENTAN', 'AMBRISENTAN', 'AMBRISENTAN', 'Ambrisentan', 'ambrisentan', 'AMBRISENTAN', 'Ambrisentan', 'Ambrisentan', 'AMBRISENTAN', 'Ambrisentan', 'Ambrisentan', 'Ambrisentan脗', 'COVC-1211572072', 'EUB0000764a', 'EUB0000764a', 'Ambrisentan', 'EUB0000764a', 'EUB0000764a', 'AMBRISENTAN', 'ambrisentan'] |
|---|
| Records Name | ['Ambrisentan', 'SID144205520', 'AMBRISENTAN', 'SID170465143', 'Ambrisentan', 'Ambrisentan', 'Ambrisentan脢', 'AMBRISENTAN', '(S)-2-(4,6-Dimethyl-pyrimidin-2-yloxy)-3-methoxy-3,3-diphenyl-propionic acid', 'Ambrisentan', 'Ambrisentan', 'ambrisentan', 'ambrisentan', 'AMBRISENTAN', 'AMBRISENTAN', None, 'Ambrisentan', 'ambrisentan', 'AMBRISENTAN', 'Ambrisentan', 'Ambrisentan', 'AMBRISENTAN', 'Ambrisentan', 'Ambrisentan', 'Ambrisentan脗', 'AMBRISENTAN', 'AMBRISENTAN', 'AMBRISENTAN', 'Ambrisentan', 'AMBRISENTAN', 'AMBRISENTAN', 'AMBRISENTAN', 'ambrisentan'] |
|---|
| Withdrawn Flag | False |
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| Orphan | 0 |
|---|
