| BioID | bio2636 |
|---|
| Name | ADRIFORANT |
|---|
| ChEMBL ID | CHEMBL1915540 |
|---|
| Molecular Formula | C13H22N6 |
|---|
| Molecular Weight | 262.36 |
|---|
| Molecular Weight (Monoisotopic) | 262.1906 |
|---|
| Type | Small molecule |
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| Max Phase | Phase 2 |
|---|
| Target ID | Tar12 |
|---|
| Target Name | Toll-like receptor 9 (TLR9) |
|---|
| Synonyms | ADRIFORANT|NVP-ZPL389-NX|PF-03893787|PF-3893787|ZPL-389|ZPL-389-NX|ZPL-3893787|ZPL389-NX |
|---|
| Smiles | CN[C@@H]1CCN(c2cc(NCC3CC3)nc(N)n2)C1 |
|---|
| Inchi | InChI=1S/C13H22N6/c1-15-10-4-5-19(8-10)12-6-11(17-13(14)18-12)16-7-9-2-3-9/h6,9-10,15H,2-5,7-8H2,1H3,(H3,14,16,17,18)/t10-/m1/s1 |
|---|
| Inchi Key | ISBHYKVAFKTATD-SNVBAGLBSA-N |
|---|
| Molecular Species | BASE |
|---|
| Targets | 18.0 |
|---|
| Bioactivities | 55.0 |
|---|
| Np Likeness Score | -1.49 |
|---|
| Records Key | ['ADRIFORANT', '13, PF-3893787', '3, PF-3893787', '5, PF-3893787', 'ADRIFORANT'] |
|---|
| Records Name | ['ADRIFORANT', 'N4-(cyclopropylmethyl)-6-[(3R)-3-(methylamino)pyrrolidin-1-yl]pyrimidine-2,4-diamine', '(R)-N4-(cyclopropylmethyl)-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine', '(R)-N4-(cyclopropylmethyl)-6-(3-(methylamino)pyrrolidin-1-yl)pyrimidine-2,4-diamine', 'ADRIFORANT'] |
|---|
| Withdrawn Flag | False |
|---|
| Orphan | 0 |
|---|
